1 00:00:00,000 --> 00:00:06,480 Okay, Chelsea, this isn't an article per se. It's a... I actually posted this on the subreddit. 2 00:00:06,480 --> 00:00:07,680 Okay, I'm intrigued. 3 00:00:08,400 --> 00:00:12,160 And it has something to do with a topic that we've been kind of covering. And 4 00:00:13,440 --> 00:00:19,120 it's kind of mundane good news, plus a push to do better in life. 5 00:00:19,120 --> 00:00:20,560 What is it? Like a PDF? 6 00:00:21,200 --> 00:00:22,960 No, it's a scientific paper. 7 00:00:22,960 --> 00:00:23,120 Okay. 8 00:00:23,120 --> 00:00:28,400 And we're just going to be reading the abstract from it. This was published April 8th, 2022. 9 00:00:28,400 --> 00:00:34,640 And it is titled Effect of Plasma and Blood Donations on Level of Per Fluorolalcal and 10 00:00:34,640 --> 00:00:40,000 Polyfluorolalcal Substances in Firefighters in Australia, a randomized clinical trial. 11 00:00:40,000 --> 00:00:43,840 And I'm just going to shorten it to PFOS for that entire thing because I hate saying it. 12 00:00:43,840 --> 00:00:48,960 So the question that they're asking in this paper is, can levels of PFOS in the blood be 13 00:00:48,960 --> 00:00:56,080 reduced by blood or plasma donations? Findings. In this randomized clinical trial of 285 firefighters, 14 00:00:56,080 --> 00:01:02,880 both blood and plasma donations resulted in significantly lower PFOS levels than observation alone. 15 00:01:03,680 --> 00:01:09,120 Does it mean than observation alone? Like just looking at someone and making the PFOS drop in 16 00:01:09,120 --> 00:01:14,080 their blood? Yeah, I think they just mean like we're just observing you, whereas these other 17 00:01:14,080 --> 00:01:20,000 ones, they told them to go donate blood. Oh, so it dropped from them taking blood out? 18 00:01:20,800 --> 00:01:25,680 Yeah, from them donating blood or plasma. Plasma donation was the most effective intervention, 19 00:01:25,680 --> 00:01:34,560 reducing mean serum per fluoro-octane sulfonate levels by 2.9 nanograms per milliliter compared 20 00:01:34,560 --> 00:01:40,880 with 1.1 nanograms per milliliter reduction with blood donations. A significant difference, 21 00:01:40,880 --> 00:01:46,800 similar changes were seen with other PFOSs. So I'm going to go a bit more into detail with it, 22 00:01:46,800 --> 00:01:51,680 but that's got to be if you don't donate blood or plasma. Well, that's a reason for sure. It 23 00:01:51,680 --> 00:01:57,600 takes plastic out of you, which is there's so much of it going in. You just if you can find a way to 24 00:01:57,600 --> 00:02:03,440 get it to go out, that's great. They just love plastic so much in the 60s. They're like, it's 25 00:02:03,440 --> 00:02:10,880 got to be in everything, even us. We want to be like 70% plastic. Yeah, you say that, but it's 26 00:02:10,880 --> 00:02:17,040 like every year we produce more and more plastic to the point like 80% of all plastic ever created 27 00:02:17,040 --> 00:02:23,680 was in the last 10 years. That's the episode we had. They started the movement to like love plastic. 28 00:02:23,680 --> 00:02:29,520 Yeah. Now we're like, oh yeah, now we love plastic so much, we have to do plastic as much as we can. 29 00:02:29,520 --> 00:02:34,480 Like this cucumber needs to be wrapped in plastic and then we need to plastic wrap them all together. 30 00:02:35,360 --> 00:02:42,000 Just lay a cucumber down. It's not natural. No, the number likes to be fully engulfed in one layer 31 00:02:42,000 --> 00:02:47,760 of plastic, separating it from its other friends, then being held together with it. Yes. Yeah. It 32 00:02:47,760 --> 00:02:54,560 can't touch skin to skin. They must touch plastic to plastic. And I would never buy a plain cucumber, 33 00:02:54,560 --> 00:03:01,280 not wrapped in three layers of plastic. What's it doing there? There's the other kind of cucumbers 34 00:03:01,280 --> 00:03:05,920 you can get at the store and they look completely different, but they don't come wrapped in plastic. 35 00:03:05,920 --> 00:03:10,960 So yeah, that's a good point. They are different cucumbers. I mean, they look different because 36 00:03:10,960 --> 00:03:16,080 they're not wrapped in plastic. Maybe that's it. Maybe those ones actually are 60% plastic and 37 00:03:16,080 --> 00:03:21,440 actually occur that way. Yeah. Don't even recognize them as a cucumber. What do you mean? 38 00:03:21,440 --> 00:03:27,600 It looks like a cucumber. Is it a zucchini? So I am going to say a bit more about this paper. 39 00:03:27,600 --> 00:03:32,960 So this was a 52 week open label randomized clinical trial enrolled participants from 40 00:03:32,960 --> 00:03:39,520 May 23rd to August 23rd, 2019. Participants were 285 fire rescue Victoria staff or contractors 41 00:03:39,520 --> 00:03:45,360 with serum levels of PFOS of five nanograms per milliliter or more who were eligible to donate 42 00:03:45,360 --> 00:03:50,080 blood had not donated blood in the last three months prior to randomization and were able to 43 00:03:50,080 --> 00:03:55,600 provide written informed consent. Analysis was performed on an intention to treat basis from 44 00:03:55,600 --> 00:04:02,160 May to July, 2021. And the firefighters with baseline of PFOS levels of five nanograms of 45 00:04:02,160 --> 00:04:07,360 milliliter or more were randomly assigned to donate plasma every six weeks for 12 months and 46 00:04:07,360 --> 00:04:13,440 donate blood every 12 weeks for 12 months or be observed only. Primary endpoint were changes. 47 00:04:13,440 --> 00:04:20,080 Results total of 285 firefighters average age was 53 were enrolled 95 were randomly assigned to 48 00:04:20,080 --> 00:04:25,840 donate plasma 95 were randomly assigned donate blood 95 were randomly assigned to be observed. 49 00:04:25,840 --> 00:04:32,640 The mean level of PFOS at 12 months was significantly reduced by plasma donations and blood donations 50 00:04:32,640 --> 00:04:38,720 but was unchanged in the observation group. The mean level of some other acronym I've never seen 51 00:04:38,720 --> 00:04:46,400 before. It's like PFOS but like the script got messed up it's PF at HXS was significantly reduced 52 00:04:46,400 --> 00:04:50,480 in the plasma donations but no significant change was observed in the blood donation or 53 00:04:50,480 --> 00:04:55,760 observation groups. Analysis between groups indicated plasma donation had a larger treatment 54 00:04:55,760 --> 00:05:01,040 effect than blood donation but both were significantly more efficacious than observation and reducing 55 00:05:01,040 --> 00:05:06,080 PFOS levels. And the conclusion plasma blood donations caused greater reduction in serum 56 00:05:06,080 --> 00:05:13,040 PFOS levels than observation alone over a 12 month period. It's interesting that plasma donations do 57 00:05:13,040 --> 00:05:17,600 more but it makes sense because when you donate plasma they take a lot more blood out of you but 58 00:05:17,600 --> 00:05:23,920 they put it back in filtered. Oh I was just gonna ask with risk of sounding stupid because I've 59 00:05:23,920 --> 00:05:29,920 never done it. Is it because your body like generates more new blood or plasma or it's because 60 00:05:29,920 --> 00:05:33,760 they filter it and put it back in filtered. It's because they filter at least that's my guess. 61 00:05:33,760 --> 00:05:39,840 I donate plasma on a bi-weekly basis so I'm getting this here apparently. I would they filter it though. 62 00:05:40,400 --> 00:05:44,320 Well they filter it just because they want to make sure that the good stuff's going in because 63 00:05:44,320 --> 00:05:49,280 they want the good stuff. Oh okay. And I think they just also don't want the gunky stuff getting like jamming 64 00:05:49,280 --> 00:05:54,240 up the machine. Basically they take all the blood out they centrifuge it spin it really fast and take 65 00:05:54,240 --> 00:05:59,280 the plasma out and put everything else back. Yeah okay. I thought it was just like a kindness that 66 00:05:59,280 --> 00:06:05,440 they're doing like let me just filter that for you. You know what it's one of those added perks 67 00:06:05,440 --> 00:06:11,360 that they should actually advertise but they don't. We'll filter your blood before you put it back in. 68 00:06:11,360 --> 00:06:17,040 I didn't know that. Yes my blood filtering guy charges 20 bucks every other week. Yeah I mean 69 00:06:17,040 --> 00:06:23,040 it's expensive it's 20 bucks that's a steal. Yeah you should actually see my old blood filtering 70 00:06:23,040 --> 00:06:30,720 guy he's pretty good. Yeah I should. I also I really like that one of our answers to this high 71 00:06:30,720 --> 00:06:35,680 technology issue that we have is bloodletting basically which is something that we use to treat 72 00:06:35,680 --> 00:06:41,280 everything in the medieval times. Yeah I mean there's a reason we tried it. Yeah maybe. Probably. 73 00:06:41,280 --> 00:06:48,080 Yeah it cures the humors. I gotta go donate plasma. What's plasma like that ectoplasm that 74 00:06:48,080 --> 00:06:54,640 they have coming out of their noses at seances? No it's our life force. It's like a yellow part 75 00:06:54,640 --> 00:07:02,160 of your blood. It kind of looks like a beer and or pee at the end of the day but yeah it's all just 76 00:07:02,160 --> 00:07:07,680 like the liquidy part of blood. Really? Not the hemoglobin. And the hemoglobin are red? Yes. 77 00:07:08,720 --> 00:07:14,320 Yes. But yeah there's some knowledge if you've learned anything please go donate blood if you 78 00:07:14,320 --> 00:07:19,680 do tell them I sent you and that they should pay us. Same with his bloodletting guy. Yeah also 79 00:07:19,680 --> 00:07:24,480 that guy my blood filter guy let him know I sent you too. He doesn't give kickbacks though. 80 00:07:24,480 --> 00:07:46,640 Anyhow you got 48 hours to do this. Okay bye. Bye. Bye Bernie.