WEBVTT

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Right now, if you look under your kitchen sink

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or maybe on a shelf in your garage, you likely

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have a pressurized can of highly engineered neurotoxins.

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Yeah, probably sitting right next to the glass

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cleaner or the extra sponges. Exactly. It is

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designed to drop a hornet from 20 feet away.

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I mean, it's poison, plain and simple. Right.

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And we keep it around for the occasional pest,

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you know, never really giving it a second thought.

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But for nearly 20 percent of substance abusers

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in certain parts of rural Kentucky, which is

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an incredibly high number, it's staggering. But

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for that population, that exact same can of bug

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spray is being melted down, crystallized and

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injected directly into their veins. Primarily

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as a substitute for methamphetamine. Welcome

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to our latest deep dive into the source material.

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Today, we are looking at a single deeply unsettling

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document detailing a phenomenon that exists on

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the extreme invisible edge of alternative substance

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abuse. It's a practice known as Wasp Dope. Right.

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And our mission for this deep dive is to really

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understand the mechanics of this practice. We're

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going to break down the improvised street chemistry,

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the devastating biological mechanisms of what

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happens when a human consumes insecticide. And

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the hidden four -decade -long history behind

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it, which is maybe the most surprising part.

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Totally. OK, let's unpack this. What exactly

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is Wasp Dope? Well, Wasp Dope, which is also

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known by street names like Wasping, Wasmeth,

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Shock Dope. Hot shots. Wait, hot shots? Yeah,

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hot shots. Katie, Katie, or zombie. Zombie? Wow.

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It basically involves the deliberate ingestion

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of common household wasp and hornet sprays. And

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the active ingredients we are focusing on in

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these commercial sprays are a class of chemicals

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called pyrethroids. OK, pyrethroids. Right. These

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are synthetic compounds. And they're actually

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modeled after natural insecticidal chemicals

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found in chrysanthemum flowers. Oh, really? Chrysanthemum.

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Yeah. But these are specifically formulated in

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a lab. to attack an insect's nervous system.

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And people are using these sprays either in combination

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with or as a direct substitute for highly addictive

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illicit substances that cause euphoria. Mainly

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meth, right? Exactly. Primarily methamphetamine

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or crack cocaine. That is just a staggering reality

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to confront right out of the gate. We are talking

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about long -distance aerosol bug spray. Yeah.

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A pressurized can filled with liquid solvent,

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propellants, and a synthetic neurotoxin. You

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can't just consume that directly out of the nozzle.

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No, definitely not. So the immediate mechanical

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hurdle here is physical chemistry. How does someone

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take a commercial aerosol product and convert

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it into something that can be smoked or injected?

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What requires an improvised and highly dangerous

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manipulation of the chemical solution. There's

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a specific case report out of Texas that actually

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outlines the primary method used to alter the

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state of the bug spray. Okay, how do they do

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it? So an individual takes the liquid insecticide

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and sprays it continuously onto a highly heated

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surface. Like a stove. Like a hot plate or a

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heated piece of metal, yeah. And when the liquid

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hits that extreme heat, the volatile components

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within the spray, specifically the aerosol propellants

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and the liquid solvent carriers, they rapidly

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evaporate or flash off. Right, because they boil

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at a lower temperature. Exactly. The active chemicals,

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the pyrethroids, have a much higher boiling point.

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So as the solvent disappears, the pyrethroids

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precipitate out of the solution and crystallize

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into this solid crust on the hot surface. Unbelievable.

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And then this resulting material is scraped up

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to be inhaled, smoked, or sometimes dissolved

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into water. and inject it intravenously. See,

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the street -level terminology often refers to

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this process as purifying the drug. Right. But

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looking at the physical chemistry, that is a

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complete illusion. Oh, completely. It's less

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like making a purified compound and more like

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boiling a pot of dirty ocean water until all

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the liquid evaporates. Yeah, and you're just

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left with the salt. Right, a hard, concentrated

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crust of salt and pollutants. Applying heat doesn't

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make the bug poison any safer or remove the neurotoxin.

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It simply condenses it. You're stripping away

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the water and the propellants, leaving an incredibly

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dense concentrated dose of the exact chemical

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designed to shut down a nervous system. What's

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fascinating here is how this improvised chemistry

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demonstrates a highly functional albeit completely

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destructive application of physical principles.

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Brute force chemistry. Right. The individuals

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doing this are utilizing evaporation and crystallization

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to bypass the intended delivery mechanism of

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a commercial product. They are isolating the

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active compound to deliver it more efficiently

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into their own bloodstream. And from the source

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material, it's not just smoking and injecting.

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No. The routes of administration don't stop there

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at all. We see documentation of huffing, snorting,

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drinking, plugging, and vaping. Literally any

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way possible. Any conceivable route to bypass

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the body's external barriers and introduce this

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concentrated pyrethroid into the blood is being

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utilized. So if this streak chemistry is successfully

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condensing these pyrethroids into a dense crystal,

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and people are finding every possible way to

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introduce it into their bloodstream, what happens

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when that massive concentrated dose hits human

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biology? It's bad. The body must immediately

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recognize it as a poison. Right, it does. Yeah,

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and the biological response is a profound systemic

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emergency. To understand the symptoms you have

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to look at how pyrethroids actually function

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on a cellular level. Okay. These synthetic chemicals

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target something called voltage -gated sodium

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channels in nerve cells. Voltage -gated sodium

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channels. Right. Normally these channels open

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and close in fractions of a second to allow electrical

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signals to pass down a nerve. That is how your

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brain tells your muscles to move or how you feel

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a sensation. Okay, that makes sense. But pyrothoids

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bind to these channels and force them to stay

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locked in the open position. Oh wow, so it's

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essentially like a stuck doorbell. The electrical

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signal just keeps firing continuously uncontrollably

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without any way for the nervous system to reset

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itself. That is an excellent way to visualize

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it. Because the nerves are firing continuously,

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the resulting symptoms are severe neurological

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chaos. What does that actually look like for

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the person? The documented physiological effects

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start with erratic behavior, extreme nausea,

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agonizing headaches, and a severe burning sensation

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in the throat. That's just the start. Yeah, as

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the continuous nerve firing overwhelms the central

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nervous system, it escalates to intense redness

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and inflammation of the extremities, auditory

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hallucinations, violence convulsions, and eventually

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the brain simply cannot sustain the electrical

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storm. The patient drops into a coma, suffers

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irreversible neurological damage, or dies. That

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explains the systemic neurological collapse,

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but there is a specific localized medical report

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from July 2000 that documents what happens at

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the actual injection site. Yes. It was published

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in the Journal of Hand Surgery, which immediately

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tells you that the localized tissue damage is

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catastrophic enough to require specialized surgical

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intervention. The July 2000 report is a really

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grim milestone in understanding the localized

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toxicity of wasp dope. Pathologists and surgeons

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examined five different patients in the United

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States who had dissolved this crystallized bug

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poison and injected it directly into the veins

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of their upper extremities. And what did they

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find? What the surgeons found was not just extreme

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inflammation. The primary pathology they diagnosed

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was a condition known as liquefaction necrosis.

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Liquefaction necrosis, I mean necrosis is the

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death of body tissue, but liquefaction necrosis

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implies something much more active and destructive

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than tissue simply dying from a lack of oxygen.

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It is a runaway immune response when a massive

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dose of concentrated foreign neurotoxins is injected

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into localized tissue, the cells in that immediate

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area die rapidly. Sure, because it's poison.

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Exactly. And the body's immune system recognizes

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this catastrophic cell death and sends a flood

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of white blood cells, specifically neutrophils

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and macrophages, to the site to clear out the

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dead tissue and attack the foreign substance.

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That sounds like what it's supposed to do. It

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is. These white blood cells are armed with powerful

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hydrolytic enzymes, which are essentially digestive

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acids designed to down bacteria or cellular debris.

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But because the toxic insult is so massive, the

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immune response overreacts? Massively overreacts.

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The white blood cells dump so many of these digestive

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enzymes into the localized area that they don't

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just clear the dead cells, they begin digesting

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the surrounding structural tissue as well. If

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we connect this to the bigger picture. you are

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seeing the body's own defense mechanisms weaponized

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against itself by the presence of the pyrethroids.

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That is terrifying. The enzymes break down the

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structural proteins of the tissue, literally

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transforming solid muscle, fat, and vascular

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tissue into a viscous liquid mass. Hence the

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liquefaction. Right. It is a profound biological

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failure that typically results in permanent disfigurement.

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the necessity for total amputation of the limb,

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or overwhelming systemic infection as that necrotic

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liquid enters the broader bloodstream. When we

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look at household bug sprays, they are generally

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safe when used as directed precisely because

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of our external biological defenses. Exactly.

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Like if you spray a hornet's nest and accidentally

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inhale a microscopic mist, the mucous membranes

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in your respiratory tract, your skin, and your

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liver enzymes can generally filter and metabolize

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that trace exposure. Your body handles it. Right.

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But when someone boils off the propellants, creates

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a concentrated crust of pyrethroids, and injects

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it directly into a vein, they are completely

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bypassing millions of years of evolutionary defense

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mechanisms. We really are. They are delivering

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an inescapable dose of synthetic poison straight

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to the tissues and the central nervous system.

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which forces us to look beyond the chemistry

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and the biology. When the physiological cost

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is this absolute, when the result is continuous

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nerve firing, comas, and your own immune system

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digesting your limbs, we have to examine the

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psychological and economic drivers. Exactly.

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Why would any human being willingly subject their

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biology to this? It's the ultimate question here.

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This brings us to the demographics. Research

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published in 2020 focused on rural Appalachian

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Kentucky and the data they uncovered recontextualizes

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this entirely. It really shifts the perspective.

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They found that 19 percent of substance abusers

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in that specific region have ingested wasp dope.

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Almost one in five. It's a massive localized

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public health crisis. It is. The researchers

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identified this as a heavily emerging trend in

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the southern United States and they correlated

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the use of wasp dope with two overwhelming factors,

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chronic homelessness and severe methamphetamine

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use. What does this all mean? We are looking

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at a region historically battered by shifting

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economic realities, resource depletion, and overlapping

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waves of the opioid and methamphetamine epidemics.

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Yeah, the compounding factors are intense. Right.

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So if someone is unhoused, completely economically

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isolated, and cut off from traditional supply

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networks for illicit drugs, their chemical dependency

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doesn't just evaporate. No, it doesn't. Addiction

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fundamentally rewires the survival hierarchy

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of the human brain. We have deep -seated evolutionary

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software that tells us to avoid consuming poison.

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Obviously. But a severe chemical dependency on

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stimulants like methamphetamine can completely

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override that survival instinct. The physiological

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need for a neurochemical release becomes the

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dominant drive. Above food, above shelter, above

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basic safety. Yes. When traditional drugs are

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unavailable or financially out of reach, the

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addiction pivots to whatever is accessible. and

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an $8 can of hornet spray is omnipresent. It's

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everywhere. It is in every hardware store, every

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supermarket, and every gas station. It is cheap,

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it is completely legal to purchase, and it is

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entirely unregulated. It is the absolute last

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resort of a desperate dependency. The brain reclassifies

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a lethal localized neurotoxin as a viable source

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of relief simply because it is the only chemical

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compound within reach. Exactly. But here's where

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it gets really interesting. Looking at the 2020

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data from Appalachian, Kentucky, it is very easy

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to frame wasp dope as a modern byproduct of the

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contemporary methamphetamine crisis. Right, like

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a recent localized trend caused by modern supply

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chain issues. Exactly. But the historical timeline

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reveals a much deeper, more systemic failure.

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There are medical and law enforcement reports

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of insecticide abuse stretching back to the 1980s.

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And the documentation goes even further back

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than that. Wait, really? Yeah, it leads back

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to a specific federal intervention. A 1979 hearing

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before the United States House of Representatives.

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1979. Specifically, the Select Committee on Narcotics

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Abuse and Control, focusing on the abuse of dangerous,

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licit, and illicit drugs. So in 1979, the United

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States government was officially documenting

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reports that American drug users were heavily

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engaged in smoking raid wasp killer. Yes. We

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are talking about the late 70s, an era publicly

00:13:06.200 --> 00:13:08.919
defined by the rise of cocaine and the shifting

00:13:08.919 --> 00:13:12.139
landscape. of heroin use. Yet simultaneously,

00:13:12.620 --> 00:13:14.799
buried in congressional testimony, there were

00:13:14.799 --> 00:13:17.460
people actively crystallizing household bug spray

00:13:17.460 --> 00:13:20.419
to alter their brain chemistry. That historical

00:13:20.419 --> 00:13:23.080
data point completely dismantles the idea that

00:13:23.080 --> 00:13:25.360
this is a new phenomenon. It really does. It

00:13:25.360 --> 00:13:27.879
synthesizes into a much darker reality. Wasp

00:13:27.879 --> 00:13:30.519
dope is a persistent four -decade -long shadow

00:13:30.519 --> 00:13:33.340
phenomena. It is an undercurrent of alternative

00:13:33.340 --> 00:13:35.759
substance abuse that has been simmering beneath

00:13:35.759 --> 00:13:38.019
the surface of the American drug landscape for

00:13:38.019 --> 00:13:40.419
nearly half a century. Just out of sight. Right.

00:13:41.019 --> 00:13:43.580
It flares up during times of economic distress,

00:13:44.019 --> 00:13:47.169
recedes, and flares up again. almost exclusively

00:13:47.169 --> 00:13:49.750
among the most vulnerable, invisible populations.

00:13:49.950 --> 00:13:52.090
The fact that federal lawmakers were documenting

00:13:52.090 --> 00:13:56.110
people smoking Raid in 1979, hand surgeons were

00:13:56.110 --> 00:13:58.710
documenting extreme tissue liquefaction from

00:13:58.710 --> 00:14:02.090
bug poison injections in the year 2000, and 20

00:14:02.090 --> 00:14:05.210
years later, we are seeing a 19 % usage rate

00:14:05.210 --> 00:14:07.990
in a specific Kentucky population. Right. It

00:14:07.990 --> 00:14:10.629
shows an unbroken chain. An incredibly tragic

00:14:10.629 --> 00:14:13.070
chain. It proves this isn't just a bizarre anomaly

00:14:13.070 --> 00:14:16.340
that occasionally pops up. It is a long - ignored

00:14:16.340 --> 00:14:19.240
problem because it disproportionately impacts

00:14:19.240 --> 00:14:21.620
people living on the absolute fringes of society.

00:14:22.039 --> 00:14:24.399
The timeline highlights a systemic blind spot.

00:14:25.299 --> 00:14:27.299
Because the individuals resorting to wasp dope

00:14:27.299 --> 00:14:30.519
are often unhoused, severely addicted, and geographically

00:14:30.519 --> 00:14:33.259
isolated, their medical emergencies and chemical

00:14:33.259 --> 00:14:36.000
dependencies rarely register on broader public

00:14:36.000 --> 00:14:37.860
health radars. Until the numbers get too big.

00:14:38.139 --> 00:14:40.259
Right, until the localized data becomes impossible

00:14:40.259 --> 00:14:42.820
to ignore, as it did in that 2020 Kentucky study.

00:14:42.990 --> 00:14:47.090
It is a profound arc to take in. We began this

00:14:47.090 --> 00:14:49.509
deep dive by looking at the improvised physical

00:14:49.509 --> 00:14:52.590
chemistry, the act of boiling away aerosol propellants

00:14:52.590 --> 00:14:56.149
on a hot plate to precipitate a dense concentrated

00:14:56.149 --> 00:14:59.529
crust of synthetic pyrethroids. We traced how

00:14:59.529 --> 00:15:02.330
those pyrethroids jam the voltage gated sodium

00:15:02.330 --> 00:15:05.070
channels in the nervous system, leading to unceasing

00:15:05.070 --> 00:15:08.070
electrical firing, convulsions and systemic collapse.

00:15:08.269 --> 00:15:10.789
And we examined the catastrophic localized biology

00:15:10.789 --> 00:15:13.350
where the immune system over reacts to the poison

00:15:13.350 --> 00:15:16.129
and utilizes hydrolytic enzymes to literally

00:15:16.129 --> 00:15:19.370
digest the body's own tissue. Right. And we follow

00:15:19.370 --> 00:15:21.950
that biological reality to its socioeconomic

00:15:21.950 --> 00:15:24.590
roots. Knowledge in this space is most valuable

00:15:24.590 --> 00:15:26.789
when we refuse to stop at the shock value of

00:15:26.789 --> 00:15:28.830
the chemistry or the medical trauma. Absolutely.

00:15:29.029 --> 00:15:31.590
This extreme behavior, this willingness to override

00:15:31.590 --> 00:15:33.990
the evolutionary fear of poison and inject a

00:15:33.990 --> 00:15:36.429
crystallized neurotoxin is ultimately a symptom.

00:15:36.590 --> 00:15:39.230
A symptom of something much larger. Exactly.

00:15:39.500 --> 00:15:42.320
It is a symptom of severe economic isolation,

00:15:42.899 --> 00:15:45.740
the relentless rewiring grip of methamphetamine

00:15:45.740 --> 00:15:49.159
addiction, and a four -decade history of vulnerable

00:15:49.159 --> 00:15:52.379
populations turning to the unregulated chemical

00:15:52.379 --> 00:15:55.080
environment around them when all other avenues

00:15:55.080 --> 00:15:58.019
of support or supply have vanished. Well said.

00:15:58.460 --> 00:16:00.519
By understanding the mechanics of wasp dope,

00:16:01.059 --> 00:16:03.980
we gain a clear clinical window into the absolute

00:16:03.980 --> 00:16:07.049
limits of human desperation. It forces us to

00:16:07.049 --> 00:16:09.889
entirely re -evaluate the mundane spaces we inhabit.

00:16:10.669 --> 00:16:12.250
Which leaves me with a final thought for you

00:16:12.250 --> 00:16:14.710
to consider long after we finish today. Yeah.

00:16:14.889 --> 00:16:16.789
Look again at the everyday chemical environment

00:16:16.789 --> 00:16:19.299
you live in. We surround our lives with highly

00:16:19.299 --> 00:16:22.399
engineered, extremely cheap, and easily accessible

00:16:22.399 --> 00:16:24.700
synthetic compounds. They're everywhere. We use

00:16:24.700 --> 00:16:26.940
them to protect our crops, clear our drains,

00:16:27.220 --> 00:16:29.500
strip paint from our walls, and eradicate pests

00:16:29.500 --> 00:16:31.940
from our garages. We interact with these products

00:16:31.940 --> 00:16:34.220
purely based on their intended design, rarely

00:16:34.220 --> 00:16:36.220
considering their underlying chemical architecture.

00:16:36.340 --> 00:16:39.039
But when extreme poverty and severe addiction

00:16:39.039 --> 00:16:42.720
change the lens of reality, those benign household

00:16:42.720 --> 00:16:45.779
items are no longer seen as tools for domestic

00:16:45.779 --> 00:16:49.149
upkeep. They become accessible targets for dangerous

00:16:49.149 --> 00:16:52.090
chemical manipulation. It's a completely different

00:16:52.090 --> 00:16:54.669
perspective. It makes you wonder what other common

00:16:54.669 --> 00:16:57.129
unregulated products sitting quietly on the shelves

00:16:57.129 --> 00:16:59.470
of your local supermarket right now represent

00:16:59.470 --> 00:17:01.649
a hidden public health crisis just waiting to

00:17:01.649 --> 00:17:03.370
be catalyzed by human desperation.
