WEBVTT

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Welcome back to The Deep Dive. Today we're tackling

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something you hear, well, all the time in fitness

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circles. This idea that doing too much training

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volume for muscle growth, you know, beyond a

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certain point, it just becomes junk volume. Right,

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the point of diminishing returns or even negative

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returns. Exactly. And it often stems from this

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assumption that strength gains kind of hit a

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ceiling at pretty low volumes, maybe five sets

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a week or so. Yeah. And people then extrapolate

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that thinking muscle growth must also stall out

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right there. But is that really the whole story?

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That's what we're digging into today. This really

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fascinating and honestly. often debated relationship

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between volume, hypertrophy, that's muscle growth,

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and, of course, strength gains. Absolutely. We've

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pulled together quite a bit of research here.

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We're talking meta -analyses, recent studies,

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really trying to challenge that common view.

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Yeah, maybe find some surprises along the way.

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I think we will. The goal here is to cut through

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some of the noise, clear up maybe some misconceptions.

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And give you, our listeners, a much clearer evidence

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-based picture. You know, so you can figure out

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what actually makes sense for your training.

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Precisely. Help you make informed decisions.

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OK, so where do we kick this off? Let's start

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with that traditional view you mentioned, the

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one that's been so dominant. Sounds good. So

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let's lay out that common argument first. You

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mentioned those Pelin meta regressions. Big analysis,

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right? Combining lots of studies. And initially,

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they seem to show strength gains kind of petering

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out beyond, what, about five sets per muscle

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group per week? That was the initial interpretation.

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Yeah, around that mark. which then led people

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to think, okay, the real growth, the contractile

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stuff, the myofibrillar hypergraphy that makes

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you stronger, that must also plateau there. Right.

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And any exercise people saw with higher volumes,

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that got dismissed. Dismissed as what, like water

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weight or something? Pretty much. Things like

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temporary muscle swelling or maybe this other

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concept, sarcoplasmic hypertrophy growth of the

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non -contractile bits, basically not real strength

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producing muscle. OK, but you hinted earlier

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that maybe this comparison isn't quite right.

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Yeah, that's putting it mildly. The direct comparison

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between the strength results and the hypertrophy

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results in that Pellin paper, it's actually quite

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misleading. Misleading? How so? I thought meta

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-analyses were supposed to give us the big picture.

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If the studies weren't the same, what's the issue?

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Well, that is the issue. They weren't based on

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the same set of studies. It's a bit of an apples

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and oranges problem. OK, explain that. So the

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strength analysis had like 66 studies, over 2

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,000 people. The hypertrophy one, only 35 studies,

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about 1 ,000 people. Right, so fewer studies

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for hypertrophy. And crucially, only 21 studies

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were actually in both analyses. Ah, okay. So

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lots of studies were only in one or the other.

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Exactly. And a whole bunch of those studies that

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were only in the strength analysis used untrained

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subjects. Untrained people. Okay, why does that

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matter so much? They get stronger, right? They

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get stronger really fast, yeah. But a huge chunk

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of that initial strength gain comes from neural

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adaptations. Basically, their brain and nerves

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just get much better at firing the muscles they

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already have. Ah, so it's learning the movement,

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becoming more efficient. Not necessarily building

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bigger muscles, especially not at low volumes.

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Precisely. And when you include all those studies

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with massive neural gains in the strength analysis,

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but not in the hypertrophy one, it really warps

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the picture. It makes it look like strength plateaus

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way earlier relative to volume than it might

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actually do if you're just looking at muscle

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growth itself. OK, that makes sense. It's kind

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of muddied the waters by mixing beginners with

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experienced lifters. So what happens if we clean

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that up? If we look only at studies with training

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where they measured both strength and muscle

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size. Does the story change? Oh, absolutely.

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It changes significantly. When you isolate those

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studies, train folks. measuring both things like

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maybe squat strength and quant thickness, a very

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different pattern. We looked at data points from

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five such studies covering nine different strength

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measurements. The groups doing higher volume

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averaging around, say, 27 sets a week. OK, that's

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quite a bit. Yeah, they gained more strength

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in seven out of those nine comparisons compared

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to the lower volume groups who were doing maybe

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19 sets a week. Seven out of nine. That's pretty

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consistent. And muscle growth. Even more consistent.

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More muscle growth in eight out of nine comparisons

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for the higher volume groups. Wow. And here's

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the kicker. The only times higher volume didn't

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lead to more strength or more growth. Those were

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in the few comparisons involving untrained lifters

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included in those specific studies. So for trained

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people, the trend was clearly higher volume,

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more strength, more size. Exactly. It directly

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contradicts that whole idea that strength can

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stall out early, undermining that core low volume

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is enough argument, at least based on this line

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of reasoning. OK, that's really important clarification.

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But then why do some meta -analyses still seem

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to show strength benefits tapering off? Even

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if muscle growth keeps going up with volume,

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is there another factor? There is, yeah. It's

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about training specificity. Think about it. Low

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volume training is often super focused. Heavy

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weights, maybe just one or two main lifts, very

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specific to building maximal strength in that

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lift. Right, like power lifting training. Exactly.

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Whereas higher volume training, it's often aiming

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for both strength and size. So you might use

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a wider range of exercises, different rep ranges,

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maybe not always lifting maximally heavy on the

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main strength test exercise. Ah, so it's less

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specific to hitting a huge one rep max on that

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one lift the study measures. Precisely. Which

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is fine. It's arguably more like how many people

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train in the real world, ecologically valid,

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as we say. But in a meta -analysis, comparing

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strength out comes, that lower specificity can

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make the higher volume groups look slightly less

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effective for peak strength than they might actually

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be overall. Gotcha. So it's not that high volume

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doesn't build strength. It's just that the way

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strength is often tested might favor the lower

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volume or specific approach sometimes. That's

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a good way to put it. It influences the results

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we see in these big analyses. OK, so we've tackled

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the data comparing strength and size gains directly.

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But let's go a level deeper. There's this underlying

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assumption about why muscles get stronger, right?

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The idea that it's all about the contractile

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proteins. Yeah, the actin and myosin cross -bridges.

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The common thinking is more cross -bridges equals

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more force. End of story. But you're saying maybe

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not the end of the story. Definitely not. That

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premise, that strength capacity is solely down

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to the number of cross -bridges is actually false.

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There's more to it. Like what? What else contributes

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to how strong a muscle actually is? Well, a big

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one is connective tissue adaptations. These improve

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something called lateral source transmission.

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Lateral force transmission. OK, break that down.

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Think of it like this. The muscle fibers generate

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force. Right, but that force has to get transmitted

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outwards through the connective tissue layers

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surrounding the fibers and the whole muscle Eventually

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pulling on the tendon and bone. Okay, like the

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force needs a pathway out exactly and resistance

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training strengthens that pathway It increases

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specific proteins at the points where fibers

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attached to this connective tissue matrix This

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directly makes the whole muscle better at transmitting

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force independent of just the fibers getting

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bigger, huh? So the scaffolding gets stronger

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too. Precisely. And this isn't some new wild

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idea. Scientists were talking about this back

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in like 1989. Wow. And here's a potentially related

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really cool idea. Challenging high -volume training

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might actually cause tiny temporary unstickings,

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adhesions between the muscle fibers and their

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surrounding connective tissue. That sounds bad,

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like damage. Well, it might involve a protein

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called tenashin C. and it seems to be part of

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the repair and remodeling process. It might temporarily

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reduce strength capacity a tiny bit while things

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get rebuilt. But it's likely necessary for strengthening

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that extracellular matrix, the scaffolding, which

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ultimately allows the muscle to handle more stress

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and continue growing. So paradoxically, while

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your muscles are growing, they might also be

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undergoing these connective tissue upgrades that

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could cause temporary dips in strength capacity.

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So strength isn't just size, it's also how well

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the whole structure works together. And improving

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that structure might involve temporary trade

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-offs. That's complex. It is. It shows that the

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relationship isn't as simple as, bigger, you'll

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always stronger right now. This whole discussion,

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you know, really highlights a bigger point about

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how we understand things in fitness and maybe

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science in general. This tension between, like,

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logical arguments and actual hard data. Absolutely.

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It's kind of a classic philosophy of science

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thing. Rationalism versus empiricism. Explain

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that. So rationalism is building arguments based

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on logic, premises, known mechanisms. A leads

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to B. B leads to C. Therefore, A leads to C.

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A lot of common fitness beliefs are built this

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way. They sound logical. OK. And empiricism.

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Empiricism is about observation and measurement.

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It's about the data. What do experiments actually

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show? In science, especially experimental science

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like exercise phis, empiricism is ultimately

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the decider. Can you give an example? BCAAs are

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a great one. Branched chain? Branched chain amino

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acids. Logically, you could argue they should

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help muscle growth, right? They're involved in

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protein synthesis, they might reduce breakdown.

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Yeah, sounds reasonable. When you actually test

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empirically, study after study shows taking extra

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BCAAs doesn't really help people build more muscle

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compared to just getting enough total protein.

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So the logic seemed sound, but the data didn't

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support it. Exactly. And that's where pseudoscience

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often lives in plausible sounding logical arguments,

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while ignoring or dismissing the direct evidence.

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Empiricism forces us to confront reality. So

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the takeaway is, trust the data even if it contradicts

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a logical theory. Pretty much. Rationalism is

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great for generating hypotheses, ideas to test,

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but empiricism is what confirms or refutes them.

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It's how our understanding evolves, sometimes

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slowly, piece by piece, based on evidence, rather

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than sticking rigidly to a logical conclusion

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that the data doesn't back up. Okay, applying

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that empirical lens then. But let's go back to

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the high -volume arguments. What about that common

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counter -argument? Oh, the extra size you see

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from high -volume, it's just temporary swelling.

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It's edema. It's not real muscle. Right. That's

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a classic rationalist -sounding dismissal. But

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what does the data say? Yeah, what does it say?

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Well, muscle swelling does happen right after

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a workout, sure, especially if it's new or unusually

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hard. But studies show it decreases pretty rapidly

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as you adapt. How rapidly? Within, say, 24 to

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72 hours, it's largely resolved. We have recent

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studies confirming this. Even with really brutal,

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eccentric training protocols, untrained people

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adapt pretty quickly, maybe within eight weeks

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or so. All the markers of damage and inflammation

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go way down. OK, so the swelling effect is mostly

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short term, especially once you're adapted. Yes.

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And here's the really crucial empirical point.

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The effect of training volume on hypertrophy

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actual muscle growth becomes more obvious in

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longer studies. Well, longer studies. If swelling

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was the main reason high volume looked better,

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you'd expect the opposite, right? You'd expect

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the difference to be biggest in short studies

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before the swelling resolves or people adapt.

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Ah, good point. But we see the opposite. Exactly.

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The fact that the benefit of higher volume is

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clearer over longer durations strongly suggests

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it's causing actual tissue growth, not just temporary

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puffiness. The empiricism refutes the it's just

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swelling argument. OK, makes sense. What about

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the other related idea, sarcoplasmic hypertrophy?

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Is that just fake muscle or puffiness too? Yeah,

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it often gets lumped in with swelling. Sarcoplasmic

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hypertrophy is the idea that the non -contractile

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parts of the muscle fiber, the fluid, glycogen,

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mitochondria, et cetera, increase disproportionately

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compared to the contractile proteins. So bigger

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fibers, but not necessarily proportionally stronger.

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That's the idea. The sort of strongest indirect

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evidence for this came from a study back in 2015.

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It suggested bodybuilders had muscle fibers that

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produced less force for their size, but that

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study has largely been refuted. A follow -up

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study in 2021 found some methodological issues

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with the original research. Oh, like what? It

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seems the apparent difference in force production

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was likely an artifact, basically. the fibers

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were swelling up during the measurement process

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itself, making them look bigger and weaker than

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they really were. Ah, so a technical issue with

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how they measured it. Exactly. So our understanding

00:12:21.529 --> 00:12:24.590
of sarcoplasmic hypertrophy as a distinct major

00:12:24.590 --> 00:12:26.610
phenomena, it's still pretty fuzzy, honestly.

00:12:26.690 --> 00:12:28.750
So we don't really know if it's a big factor?

00:12:29.029 --> 00:12:31.850
We don't. There are hypotheses. Maybe it's temporary.

00:12:31.889 --> 00:12:34.129
Maybe it happens before myofibrillar growth kicks

00:12:34.129 --> 00:12:36.509
in. Maybe it happens only when fibers get really

00:12:36.509 --> 00:12:39.769
big. But it's also incredibly hard to measure

00:12:39.769 --> 00:12:42.879
accurately. Think about it, muscle biopsies take

00:12:42.879 --> 00:12:46.120
a tiny, tiny sample, try to precisely measure

00:12:46.120 --> 00:12:48.899
the proportion of contractile versus noncontractile

00:12:48.899 --> 00:12:52.399
stuff in that tiny sample and then extrapolate

00:12:52.399 --> 00:12:55.120
to the whole muscle. It's really challenging.

00:12:55.519 --> 00:12:59.059
So the it's just circle plasmic argument doesn't

00:12:59.059 --> 00:13:01.379
have super strong evidence behind it either not

00:13:01.379 --> 00:13:03.779
really strong direct evidence No, the bulk of

00:13:03.779 --> 00:13:05.720
the evidence still points towards higher volumes

00:13:05.720 --> 00:13:08.139
leading to more actual contractile tissue growth

00:13:08.139 --> 00:13:10.480
over time Okay, so bringing this back to practical

00:13:10.480 --> 00:13:13.419
advice based on the data We do have where does

00:13:13.419 --> 00:13:15.940
the evidence seem solid in terms of weekly sets?

00:13:15.940 --> 00:13:17.759
Is there a number we can feel confident about?

00:13:17.950 --> 00:13:20.110
Yeah, looking at where the data is reasonably

00:13:20.110 --> 00:13:21.870
dense, we can be pretty confident recommending

00:13:21.870 --> 00:13:24.870
up to around, say, 25 sets per muscle group per

00:13:24.870 --> 00:13:27.070
week. 25 sets. Beyond that point, the studies

00:13:27.070 --> 00:13:29.649
become much fewer and farther between, so our

00:13:29.649 --> 00:13:31.990
confidence level in making recommendations naturally

00:13:31.990 --> 00:13:34.370
drops off. Right. But what about the upper limit?

00:13:34.470 --> 00:13:37.750
You mentioned studies going up to 45 sets still

00:13:37.750 --> 00:13:40.149
showing benefits. Is there any evidence for that

00:13:40.149 --> 00:13:43.110
inverted U where doing too much actually makes

00:13:43.110 --> 00:13:45.509
you grow less? Has any study found that yet?

00:13:45.610 --> 00:13:47.370
That's the million -dollar question, isn't it?

00:13:47.450 --> 00:13:50.370
The honest answer is, we don't have clear evidence

00:13:50.370 --> 00:13:53.529
for that downturn yet. Really? Not even at 45

00:13:53.529 --> 00:13:55.490
sets? The studies pushing those high volumes,

00:13:55.590 --> 00:13:59.049
like 30, 40, 45 sets, they still generally show

00:13:59.049 --> 00:14:01.950
more growth compared to lower volumes. Now, theoretically,

00:14:02.230 --> 00:14:04.570
that inverted U should exist, right? You can't

00:14:04.570 --> 00:14:07.110
just add sets infinitely. Yeah, eventually you'd

00:14:07.110 --> 00:14:09.970
just break down. Exactly. But based purely on

00:14:09.970 --> 00:14:12.129
the hypertrophy data published so far, we haven't

00:14:12.129 --> 00:14:15.360
clearly identified that peak and downturn. Maybe

00:14:15.360 --> 00:14:17.659
the next study will find it. But for now, the

00:14:17.659 --> 00:14:19.500
limit seems to be higher than previously thought.

00:14:19.580 --> 00:14:21.840
Certainly higher than that old 10 -20 set idea.

00:14:22.240 --> 00:14:24.840
Speaking of that 10 -20 sets, where did that

00:14:24.840 --> 00:14:26.500
recommendation even come from? It feels like

00:14:26.500 --> 00:14:28.759
it was everywhere for a while. It really was.

00:14:29.179 --> 00:14:31.480
But it was never based on super strong direct

00:14:31.480 --> 00:14:34.159
evidence showing that's the optimal range. It

00:14:34.159 --> 00:14:37.299
seems to have stemmed from maybe a bit of a lazy

00:14:37.299 --> 00:14:39.620
interpretation, as some have called it, of a

00:14:39.620 --> 00:14:43.740
2017 meta -analysis. Or so. That analysis basically

00:14:43.740 --> 00:14:46.500
just lumped everything above 9 or 10 sets into

00:14:46.500 --> 00:14:49.740
one single high -volume category. It didn't really

00:14:49.740 --> 00:14:52.340
differentiate between 12 sets, 20 sets, or 30

00:14:52.340 --> 00:14:54.980
sets. Ah, so it just showed more than 10 is better

00:14:54.980 --> 00:14:57.000
than less than 10, but not how much more is better.

00:14:57.100 --> 00:14:59.500
Pretty much. And critically, during that period,

00:14:59.740 --> 00:15:01.320
there were a couple of influential studies that

00:15:01.320 --> 00:15:04.059
did seem to support lower volumes, like maybe

00:15:04.059 --> 00:15:06.919
5, 10 sets being optimal. OK. But those studies

00:15:06.919 --> 00:15:09.080
were later retracted because the data was found

00:15:09.080 --> 00:15:11.600
to be fabricated. Wow, seriously. Fabricated

00:15:11.600 --> 00:15:14.720
data. Yeah. And the time between when those studies

00:15:14.720 --> 00:15:17.080
were published and when they were retracted definitely

00:15:17.080 --> 00:15:19.179
skewed the perception and contributed heavily

00:15:19.179 --> 00:15:22.139
to that 10, 20 sets is probably enough consensus.

00:15:22.559 --> 00:15:24.419
Remove those faulty studies and the picture looks

00:15:24.419 --> 00:15:27.100
quite different. OK, that context is really important.

00:15:27.379 --> 00:15:31.919
But let's talk feasibility doing, say, 30 plus

00:15:31.919 --> 00:15:34.480
sets per muscle group. for all your muscle groups.

00:15:34.879 --> 00:15:37.379
That sounds like living in the gym. Is that even

00:15:37.379 --> 00:15:39.399
realistic? It's definitely a significant commitment,

00:15:39.559 --> 00:15:41.940
no doubt about it. When you look at surveys of

00:15:41.940 --> 00:15:44.080
competitive bodybuilders, you do see some reporting

00:15:44.080 --> 00:15:47.320
volumes in that 30 -40 set range per muscle group

00:15:47.320 --> 00:15:49.519
per week. Some do it, okay. But it's not the

00:15:49.519 --> 00:15:51.919
norm. The typical range reported is usually more

00:15:51.919 --> 00:15:55.200
like 12 to 24 sets. And the research we have

00:15:55.200 --> 00:15:57.580
doesn't strongly suggest high volumes only work

00:15:57.580 --> 00:16:01.350
if you focus on one or two muscles. Studies often

00:16:01.350 --> 00:16:03.210
have participants train multiple muscle groups

00:16:03.210 --> 00:16:05.669
with high volumes and see benefits across the

00:16:05.669 --> 00:16:08.470
board. But the downsides? Time, obviously. It

00:16:08.470 --> 00:16:11.210
takes a lot longer. And importantly, a higher

00:16:11.210 --> 00:16:13.710
risk of joint aches, tendon issues, that sort

00:16:13.710 --> 00:16:15.490
of thing, especially if you jump into it too

00:16:15.490 --> 00:16:18.690
quickly. So slow and steady ramp up is key if

00:16:18.690 --> 00:16:20.899
you try it. Absolutely crucial. We're talking

00:16:20.899 --> 00:16:23.179
gradually increasing over maybe three to six

00:16:23.179 --> 00:16:25.360
months, not trying to double your volume overnight.

00:16:25.759 --> 00:16:28.059
Your connective tissues need time to adapt. You

00:16:28.059 --> 00:16:30.139
mentioned earlier that not everyone responds

00:16:30.139 --> 00:16:32.779
the same way, though. Can you elaborate on that?

00:16:33.059 --> 00:16:35.639
Why might higher volumes work wonders for one

00:16:35.639 --> 00:16:38.399
person, but not another? Right. Individual response

00:16:38.399 --> 00:16:41.539
is huge here. While on average higher volume

00:16:41.539 --> 00:16:44.460
leads to more growth, the spread is wide. You

00:16:44.460 --> 00:16:47.480
might have roughly a quarter of people who respond

00:16:47.480 --> 00:16:50.740
dramatically better to high volume. Okay. Maybe

00:16:50.740 --> 00:16:53.139
another quarter see a moderate improvement. Another

00:16:53.139 --> 00:16:55.159
quarter might see no real difference compared

00:16:55.159 --> 00:16:57.360
to moderate volume. And then maybe another quarter

00:16:57.360 --> 00:16:59.639
actually do better on lower volumes. A quarter

00:16:59.639 --> 00:17:03.000
doing better on lower. Interesting. Why the difference?

00:17:03.139 --> 00:17:05.039
We don't know for sure, but there are potential

00:17:05.039 --> 00:17:08.920
reasons. Genetics play a role, obviously. Differences

00:17:08.920 --> 00:17:11.299
in things like ribosome biogenesis, how quickly

00:17:11.299 --> 00:17:13.940
your cells can build proteins. Satellite cell

00:17:13.940 --> 00:17:16.140
excavation, those are muscle stem cells involved

00:17:16.140 --> 00:17:19.019
in repair and growth. Fiber type distribution

00:17:19.019 --> 00:17:22.220
could matter too. People with more fatigue resistant

00:17:22.220 --> 00:17:25.319
type I fibers might tolerate and benefit more

00:17:25.319 --> 00:17:27.960
from higher volumes. Type I, the endurance fibers.

00:17:28.319 --> 00:17:30.799
Yeah, but they still grow quite a bit. And then

00:17:30.799 --> 00:17:34.589
there's the real world factor. In a controlled

00:17:34.589 --> 00:17:36.529
study, people might be pushed harder than they

00:17:36.529 --> 00:17:38.849
typically push themselves in their regular training.

00:17:39.349 --> 00:17:41.309
Maybe some people just don't maintain the necessary

00:17:41.309 --> 00:17:43.730
intensity when volume gets really high on their

00:17:43.730 --> 00:17:46.670
own. That makes sense. So genetics, fiber type,

00:17:47.150 --> 00:17:50.069
maybe even just practical effort levels. Given

00:17:50.069 --> 00:17:52.609
that high volumes can work, at least on average,

00:17:53.329 --> 00:17:56.750
why don't we see more people doing like 40 plus

00:17:56.750 --> 00:18:00.180
sets routinely in gyms everywhere? Besides the

00:18:00.180 --> 00:18:02.099
time factor you mentioned time is probably the

00:18:02.099 --> 00:18:04.559
biggest practical barrier. Let's be real getting

00:18:04.559 --> 00:18:07.599
maybe 20 % better results But spending 50 % more

00:18:07.599 --> 00:18:10.299
time in the gym that trade -off isn't worth it

00:18:10.299 --> 00:18:12.460
for most people who aren't competitive bodybuilders

00:18:12.460 --> 00:18:14.839
Yeah, the diminishing returns hit practicality

00:18:14.839 --> 00:18:17.700
hard Exactly. And there might also be a systemic

00:18:17.700 --> 00:18:20.180
recovery issue, even if each individual muscle

00:18:20.180 --> 00:18:22.299
could handle more. Maybe your overall system,

00:18:22.960 --> 00:18:25.579
nervous system, endocrine system, joints hits

00:18:25.579 --> 00:18:27.640
a recovery bottleneck when you try to push everything

00:18:27.640 --> 00:18:30.000
super hard simultaneously. Like a total body

00:18:30.000 --> 00:18:32.720
stress limit. Potentially, yeah. It's easier

00:18:32.720 --> 00:18:35.339
to blast one or two body parts with insane volume

00:18:35.339 --> 00:18:37.359
than it is to do it for everything all at once,

00:18:37.640 --> 00:18:40.220
week after week. OK, another question. These

00:18:40.220 --> 00:18:42.920
studies are often, what, 8, 10, 12 weeks long?

00:18:43.240 --> 00:18:46.279
They might show, say, 10 % more growth with high

00:18:46.279 --> 00:18:48.779
volume in that time. Can we just extrapolate

00:18:48.779 --> 00:18:51.539
that out? Does that mean you'll gain 10 % more

00:18:51.539 --> 00:18:53.759
muscle every three months than definitely if

00:18:53.759 --> 00:18:56.400
you stick with high volume? Ah, no, definitely

00:18:56.400 --> 00:18:59.519
not. Muscle growth isn't linear like that. It

00:18:59.519 --> 00:19:01.799
follows more of a logarithmic curve. Meaning

00:19:01.799 --> 00:19:04.119
it slows down over time. Exactly. Your gains

00:19:04.119 --> 00:19:06.339
are fastest when you're starting out or recovering

00:19:06.339 --> 00:19:08.819
lost muscle, and they slow down progressively

00:19:08.819 --> 00:19:10.759
as you get closer to your genetic potential.

00:19:11.460 --> 00:19:13.539
Higher volume seems to lead to faster gains,

00:19:13.680 --> 00:19:15.799
especially early on. So you get more growth sooner?

00:19:16.079 --> 00:19:18.859
Yes, and likely more total growth over, say,

00:19:19.000 --> 00:19:21.200
the first year or two compared to lower volumes.

00:19:21.900 --> 00:19:24.680
But it's possible that over a very long time

00:19:24.680 --> 00:19:27.160
frame, like five or 10 years, the total amount

00:19:27.160 --> 00:19:29.660
of muscle gain between someone doing moderate

00:19:29.660 --> 00:19:32.880
volume versus high volume might start to converge

00:19:32.880 --> 00:19:34.920
somewhat as they both approach their genetic

00:19:34.920 --> 00:19:37.710
ceiling. Hmm, interesting. But very low volume

00:19:37.710 --> 00:19:39.750
would still be lagging behind. Oh, yeah. Very

00:19:39.750 --> 00:19:42.349
low volumes, like just a few sets per week, are

00:19:42.349 --> 00:19:44.730
almost certainly suboptimal for maximizing long

00:19:44.730 --> 00:19:47.170
-term growth for most people. What about volume

00:19:47.170 --> 00:19:49.650
cycling? You hear about people increasing volume

00:19:49.650 --> 00:19:52.430
for a while, then backing off to resensitize,

00:19:52.450 --> 00:19:54.609
then pushing up again. Is there anything to that?

00:19:54.869 --> 00:19:57.809
That's an interesting theory. The idea is based

00:19:57.809 --> 00:20:01.150
on progressive overload that you need continuously

00:20:01.150 --> 00:20:05.460
increasing stress. So maybe Constantly pushing

00:20:05.460 --> 00:20:08.640
high volume leads to accommodation, but cycling

00:20:08.640 --> 00:20:11.000
yet allows you to keep adapting. Does the evidence

00:20:11.000 --> 00:20:14.059
support it? There's some indirect physiological

00:20:14.059 --> 00:20:17.000
rationale, maybe some suggestive findings, but

00:20:17.000 --> 00:20:19.240
no really definitive studies validating volume

00:20:19.240 --> 00:20:22.259
cycling as superior to just maintaining a consistently

00:20:22.259 --> 00:20:25.539
appropriate volume yet. However, even if cycling

00:20:25.539 --> 00:20:27.539
turns out to be beneficial, the principle likely

00:20:27.539 --> 00:20:31.000
still holds. Training with generally higher volumes,

00:20:31.480 --> 00:20:33.960
even if you cycle them down periodically, seems

00:20:33.960 --> 00:20:35.920
to be more effective than training with consistently

00:20:35.920 --> 00:20:38.720
low volumes. So the baseline average volume still

00:20:38.720 --> 00:20:41.240
matters? It seems to. Okay, let's revisit the

00:20:41.240 --> 00:20:44.200
mechanism. At the most basic level, how does

00:20:44.200 --> 00:20:47.539
doing more sets lead to more muscle? Is it just

00:20:47.539 --> 00:20:51.059
more stimulus, more growth? That's the simplest

00:20:51.059 --> 00:20:55.440
and likely largely correct answer. A greater

00:20:55.440 --> 00:20:58.319
total stimulus triggers a greater adaptive response,

00:20:58.420 --> 00:21:00.940
up to a point. Is there any more nuance to it?

00:21:01.259 --> 00:21:04.279
Potentially. One idea relates back to fiber types.

00:21:04.799 --> 00:21:07.039
Higher volumes, often involving more reps and

00:21:07.039 --> 00:21:09.700
maybe shorter rests, might be better at stimulating

00:21:09.700 --> 00:21:12.400
those fatigue -resistant type I fibers. Which

00:21:12.400 --> 00:21:14.400
you said contribute significantly to overall

00:21:14.400 --> 00:21:16.640
size. They really do. They might be underestimated

00:21:16.640 --> 00:21:19.519
in traditional strength training. Also, think

00:21:19.519 --> 00:21:21.819
about the bioenergetics, the energy systems within

00:21:21.819 --> 00:21:24.640
the muscle. Things like capillary density, more

00:21:24.640 --> 00:21:27.119
blood supply, and mitochondrial function, energy

00:21:27.119 --> 00:21:29.380
production, are crucial for supporting muscle

00:21:29.380 --> 00:21:32.200
growth. Higher volumes might promote these adaptations

00:21:32.200 --> 00:21:34.619
more effectively, removing potential metabolic

00:21:34.619 --> 00:21:36.640
roadblocks to fibers getting bigger. So it's

00:21:36.640 --> 00:21:38.779
not just triggering the growth signal, but also

00:21:38.779 --> 00:21:41.079
building the support systems needed for that

00:21:41.079 --> 00:21:42.640
growth. That could definitely be part of the

00:21:42.640 --> 00:21:44.839
picture, yeah. We talked about strength versus

00:21:44.839 --> 00:21:48.599
size earlier. How good is tracking your strength

00:21:48.599 --> 00:21:51.019
gains as an indicator whether you're actually

00:21:51.019 --> 00:21:53.359
gaining muscle, especially in these shorter time

00:21:53.359 --> 00:21:55.839
frames like a typical study? It's tricky. Over

00:21:55.839 --> 00:21:58.940
the long term, for a specific individual who

00:21:58.940 --> 00:22:01.140
is already trained and consistent with their

00:22:01.140 --> 00:22:03.859
technique, tracking strengths can be a reasonably

00:22:03.859 --> 00:22:06.839
good proxy for hypertrophy. If your lifts are

00:22:06.839 --> 00:22:09.259
consistently going up over months and years,

00:22:09.700 --> 00:22:11.799
you're probably gaining muscle. Okay, long term

00:22:11.799 --> 00:22:13.710
it works better. But in the short term, like

00:22:13.710 --> 00:22:16.809
those 8 -12 week studies, strength is often a

00:22:16.809 --> 00:22:19.589
poor indicator. Why? Because as we discussed,

00:22:19.970 --> 00:22:22.329
those early strength gains are so heavily dominated

00:22:22.329 --> 00:22:24.470
by neural adaptations, just getting better at

00:22:24.470 --> 00:22:27.009
the lift. The point where hypertrophy becomes

00:22:27.009 --> 00:22:29.869
the main driver of strength increases is probably

00:22:29.869 --> 00:22:32.690
around that 8 -12 week mark or even later for

00:22:32.690 --> 00:22:34.549
some exercises. Right, when the study often ends.

00:22:34.759 --> 00:22:37.640
Exactly. Plus, in smaller studies, you get more

00:22:37.640 --> 00:22:40.440
random variation sampling variance. One small

00:22:40.440 --> 00:22:42.500
study might show strength going up without much

00:22:42.500 --> 00:22:45.400
size gain. Another might show the opposite, just

00:22:45.400 --> 00:22:47.940
due to chance or measurement error, even if the

00:22:47.940 --> 00:22:50.140
underlying relationship across many studies is

00:22:50.140 --> 00:22:52.690
clearer. So don't put too much stock in week

00:22:52.690 --> 00:22:54.829
-to -week strength changes as proof of muscle

00:22:54.829 --> 00:22:58.329
gain, especially early on. Generally, no. Look

00:22:58.329 --> 00:23:00.150
at longer trends. Let's talk about diminishing

00:23:00.150 --> 00:23:02.710
returns again. You said higher volume leads to

00:23:02.710 --> 00:23:04.809
more growth, but with diminishing returns. Can

00:23:04.809 --> 00:23:07.190
you clarify what that means? Does diminishing

00:23:07.190 --> 00:23:10.109
returns mean it's not worth doing? That's a common

00:23:10.109 --> 00:23:12.509
misunderstanding. Diminishing returns just means

00:23:12.509 --> 00:23:14.849
each additional unit of input gives you less

00:23:14.849 --> 00:23:17.029
output than the previous one. OK. So maybe going

00:23:17.029 --> 00:23:19.250
from 5 to 10 sets gives you x amount of growth.

00:23:19.869 --> 00:23:21.990
Going from 10 to 15 sets gives you less than

00:23:21.990 --> 00:23:25.170
x, maybe 0 .7x. Going from 15 to 20 gives you

00:23:25.170 --> 00:23:28.210
even less, maybe 0 .5x. Right, the benefit per

00:23:28.210 --> 00:23:31.190
set decreases. Yes. But importantly, diminishing

00:23:31.190 --> 00:23:33.630
returns does not mean lower total returns. In

00:23:33.630 --> 00:23:36.089
that example, 20 sets still gave you more total

00:23:36.089 --> 00:23:40.200
growth. x plus 0 .7x plus 0 .5x, then 10 sets,

00:23:40.299 --> 00:23:43.779
just x. Ah, okay. So even though the efficiency

00:23:43.779 --> 00:23:46.640
per set goes down, the total result can still

00:23:46.640 --> 00:23:50.099
go up. Exactly. So the goal of maximizing efficiency,

00:23:50.819 --> 00:23:53.640
most growth per set, often favoring lower volumes,

00:23:53.660 --> 00:23:57.019
and the goal of maximizing total results, most

00:23:57.019 --> 00:23:59.759
growth overall, often requiring higher volumes,

00:24:00.220 --> 00:24:02.440
can be contradictory. And people need to decide

00:24:02.440 --> 00:24:04.460
which goal is more important to them considering

00:24:04.460 --> 00:24:08.180
the trade -offs. Precisely. Time, effort, injury

00:24:08.180 --> 00:24:11.279
risk, recovery capacity, all need to be weighed

00:24:11.279 --> 00:24:13.839
against how much growth you're aiming for. OK,

00:24:13.940 --> 00:24:17.039
so let's try to synthesize all this. What's the

00:24:17.039 --> 00:24:18.920
practical recommendation for someone listening?

00:24:19.059 --> 00:24:21.339
How should they figure out their ideal volume?

00:24:21.559 --> 00:24:23.339
Well, first things first. If what you're currently

00:24:23.339 --> 00:24:25.259
doing is working, if you're consistently making

00:24:25.259 --> 00:24:28.839
progress, you're happy with don't change anything.

00:24:29.000 --> 00:24:31.359
Don't fix what ain't broke. Exactly. A bird in

00:24:31.359 --> 00:24:33.220
the hand is worth two in the bush. Don't mess

00:24:33.220 --> 00:24:35.380
with success just because some studies suggest

00:24:35.380 --> 00:24:37.359
something else might be slightly more optimal

00:24:37.359 --> 00:24:39.900
on average. Good advice. But what if you have

00:24:39.900 --> 00:24:42.380
plateaued, or you feel like your progress is

00:24:42.380 --> 00:24:45.339
way slower than you'd like? Then, based on everything

00:24:45.339 --> 00:24:47.720
we've discussed, increasing your training volume

00:24:47.720 --> 00:24:51.319
is a very valid evidence -based strategy to try.

00:24:52.099 --> 00:24:53.980
How should someone approach that? Just double

00:24:53.980 --> 00:24:57.420
their sets next week? Definitely not. Gradual

00:24:57.420 --> 00:25:00.049
increase is key. A reasonable starting point

00:25:00.049 --> 00:25:02.910
might be to aim for about a 20 % increase in

00:25:02.910 --> 00:25:05.950
weekly sets for a target muscle group. 20%, okay.

00:25:06.190 --> 00:25:08.410
And then what? Stick with that for maybe two,

00:25:08.490 --> 00:25:10.990
four weeks. See how recovery feels, then maybe

00:25:10.990 --> 00:25:13.809
add another 20 % if things are going well. Do

00:25:13.809 --> 00:25:16.049
this gradually over, say, two, three months.

00:25:16.170 --> 00:25:17.890
And how do you know if it's working? Monitor

00:25:17.890 --> 00:25:20.529
your progress objectively. Are your training

00:25:20.529 --> 00:25:23.559
loads? weight on the bar for the same reps, starting

00:25:23.559 --> 00:25:25.940
to consistently exceed what you were doing before

00:25:25.940 --> 00:25:28.900
on the original lower volume, that's a great

00:25:28.900 --> 00:25:31.259
sign you're responding well. So getting stronger

00:25:31.259 --> 00:25:34.200
on the higher volume is key. Yes. If your loads

00:25:34.200 --> 00:25:36.299
are just staying the same despite doing more

00:25:36.299 --> 00:25:38.380
sets, that's kind of a neutral signal. You're

00:25:38.380 --> 00:25:40.359
building work capacity, maybe some endurance,

00:25:40.759 --> 00:25:43.119
but perhaps not driving maximal hypertrophy effectively.

00:25:43.480 --> 00:25:45.200
And if your training loads actually start to

00:25:45.200 --> 00:25:47.240
decrease and stay lower after a couple months

00:25:47.240 --> 00:25:49.829
on a higher volume, That's a bad sign. That's

00:25:49.829 --> 00:25:52.009
a pretty strong sign that that level of volume

00:25:52.009 --> 00:25:54.670
isn't productive for you right now and you should

00:25:54.670 --> 00:25:57.529
probably back off or explore other strategies

00:25:57.529 --> 00:26:00.549
like changing exercises, improving nutrition,

00:26:01.309 --> 00:26:04.130
or focusing on recovery. What about those specialization

00:26:04.130 --> 00:26:06.390
blocks you mentioned? Yeah, focusing high volume

00:26:06.390 --> 00:26:08.410
on just one or two muscle groups for a period

00:26:08.410 --> 00:26:10.809
while maintaining lower volume elsewhere can

00:26:10.809 --> 00:26:13.009
be a great way to test your individual response.

00:26:13.509 --> 00:26:15.289
It gives you a clearer signal because you're

00:26:15.289 --> 00:26:17.369
not trying to push everything at once. It's about

00:26:17.369 --> 00:26:20.349
finding your sweet spot through careful experimentation.

00:26:20.750 --> 00:26:23.450
Exactly. The goal isn't necessarily to hit some

00:26:23.450 --> 00:26:27.130
magic number like 25 sets or to do the absolute

00:26:27.130 --> 00:26:30.250
maximum volume you can possibly tolerate. The

00:26:30.250 --> 00:26:32.029
goal is finding the amount of volume that you

00:26:32.029 --> 00:26:34.289
need to stimulate the progress you want, balancing

00:26:34.289 --> 00:26:37.569
results with recovery, time, and enjoyment. Individual

00:26:37.569 --> 00:26:40.509
context is everything. Wow, okay, we really went

00:26:40.509 --> 00:26:43.289
deep today. We unpacked why those old assumptions

00:26:43.289 --> 00:26:45.269
about strength plateaus limiting muscle growth

00:26:45.269 --> 00:26:47.230
don't really hold up when you look closely at

00:26:47.230 --> 00:26:49.049
the data, especially for trained individuals.

00:26:49.470 --> 00:26:52.250
Yeah, we saw that higher volumes generally do

00:26:52.250 --> 00:26:54.930
lead to more growth and importantly more strength

00:26:54.930 --> 00:26:57.410
gains, too, contrary to some interpretations.

00:26:57.680 --> 00:26:59.839
And we touched on the role of connective tissue,

00:26:59.980 --> 00:27:02.599
that strength isn't just muscle fiber size and

00:27:02.599 --> 00:27:05.640
the importance of relying on empirical data over

00:27:05.640 --> 00:27:08.660
just logical arguments. Definitely. Trusting

00:27:08.660 --> 00:27:11.660
the data, even when it's complex or contradicts

00:27:11.660 --> 00:27:15.279
old beliefs, is key. This whole exploration,

00:27:15.579 --> 00:27:17.599
it's more than just how many sets should I do.

00:27:17.720 --> 00:27:19.839
It's really about thinking critically, right?

00:27:20.160 --> 00:27:22.180
Applying these scientific principles to your

00:27:22.180 --> 00:27:25.039
own training journey. Absolutely. And maybe it

00:27:25.039 --> 00:27:27.400
prompts a question for you, the listener. If

00:27:27.400 --> 00:27:30.430
your goal is to optimize your progress, What

00:27:30.430 --> 00:27:32.569
aspects of your current routine are you just

00:27:32.569 --> 00:27:34.609
taking for granted based on old assumptions?

00:27:34.869 --> 00:27:37.089
Yeah, what new possibilities might open up if

00:27:37.089 --> 00:27:39.029
you looked at your training with this fresh evidence

00:27:39.029 --> 00:27:41.289
-based perspective we've discussed today? Something

00:27:41.289 --> 00:27:43.650
to think about. Keep exploring, keep questioning,

00:27:43.950 --> 00:27:45.809
keep learning. Couldn't said it better myself.

00:27:46.329 --> 00:27:47.990
Thanks for joining us on the Deep Dive.
