WEBVTT

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Have you ever stopped and really thought about

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how crazy it is that your brain just figures

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out the world? Seriously, there's this constant

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flood of information hitting you from all your

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senses, sights, sounds, smells, everything, right?

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But you don't have to consciously think about

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putting it all together. It just like. happens

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automatically. It really is remarkable when you

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put it that way. Right. So how does that even

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work? Like, how does the brain take all that

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raw input and just create this like this whole

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reality that we experience? Yeah, that's a question

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that neuroscientists have been grappling with

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for, well, I mean, forever, really. And it feels

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so effortless for us, doesn't it? Totally. And

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speaking of this whole like figuring things out

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thing, there's this theory I came across recently

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that I just like. had to dive into. It's called

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the free energy principle or FEP. Oh yeah, I've

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heard of that. Yeah and get this was developed

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by this like brilliant neuroscientist Dr. Carl

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Friston and the really cool thing is there's

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been some like really solid experimental validation

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of it recently. So like this deep dive we're

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going to try to unpack what this FEP is all about

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and really dig into how it's like changing the

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way we think about how our brains learn. It's

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a timely discussion, for sure. I mean, for years

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now, we've seen these huge advances in artificial

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intelligence, particularly in machine learning.

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But they've kind of hit a wall in some fundamental

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ways, wouldn't you say? Totally. Like, think

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about it. These AI systems, they need just mountains

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of data to work, right? And then even when they

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work well, it's often really hard to understand

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how they actually got to their conclusions. Like,

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we call it the black box problem. Yeah, exactly.

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And there's this ongoing debate, you know, is

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it truly intelligent, or is it just really sophisticated

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pattern recognition? It's not quite the same

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thing, right? Right. And that's what makes this

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FEP approach so interesting. It's a totally different

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way of looking at intelligence, both for us and

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for potential AI. You know, so in this deep dive,

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our goal is to really get to the heart of what

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the FPP is all about and understand why this

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recent proof is such a big deal, not just for

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understanding our own minds, but like for the

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whole future of AI too. And, you know, this deep

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dive was actually inspired by some awesome resources

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that you, our listeners, shared with us. So thank

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you for that. Absolutely. So to kick things off,

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let's think about the sheer scale of what our

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brains are dealing with every single second.

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You know, you mentioned this flood of information,

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and it truly is like an ocean, just this massive

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amount of data constantly hitting our senses.

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It's kind of overwhelming when you think about

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it like that. Right. And our brains somehow manage

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to filter through all of that, extract what's

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important, and make sense of it all. So like,

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think about trying to follow a conversation in

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a really noisy crowded room, or like trying to

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pick out a friend's face in a huge crowd. That's

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what our brains are doing all the time, right?

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Exactly. And it's not a simple task at all. It's

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like trying to solve this incredibly complicated

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puzzle in reverse. The world throws all these

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effects at us, the sounds, the sights, and our

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brains have to figure out the hidden causes.

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What's making that specific sound? What's causing

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that particular pattern of light that our eyes

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are picking up? It's like being a detective,

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but you only have the clues and you have to work

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backward to figure out the crime And to make

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it even more complicated, the same underlying

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cause can produce wildly different effects depending

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on all sorts of things, right? Precisely. Like,

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think about recognizing someone's face. That

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same face can look totally different depending

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on the lighting, their expression, the angle

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you're seeing them from, all sorts of variables.

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But our brains still manage to, like, instantly

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recognize that it's the same person. It's mind

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-blowing. It is. And this is where the free energy

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principle comes in. This theory proposes that

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our brains aren't just passively absorbing all

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this sensory data like a sponge. Instead, it

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suggests that our neurons are constantly generating

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these what we call top -down predictions about

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what they're going to encounter. It's like our

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brains are actively trying to guess what's going

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to happen next, to explain away the incoming

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sensory data before it even fully arrives. So

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it's like our brains are making these mini hypotheses

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about the world all the time. Exactly. And those

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predictions aren't always going to be accurate.

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Right. And that's where learning comes in. When

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there's a mismatch between our predictions and

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the actual sensory input we receive, that creates

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what's called a prediction error. A prediction

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error. Yeah. And those prediction errors act

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as a signal to the brain that its internal model

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of the world Its current best guess about how

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things work isn't quite right. So the brain uses

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those errors to learn and improve its predictions.

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Exactly. It's constantly updating its beliefs,

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refining its internal model so that it can make

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better, more accurate predictions in the future.

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You can think of the brain as this incredibly

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sophisticated inference machine, constantly trying

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to figure out the best explanation for the sensory

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data it's receiving. So it's not just about reacting

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to what's happening, but more about proactively

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trying to understand the underlying causes, the

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why behind everything. Nicely. That makes a lot

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of sense. And you know, it's interesting because

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for a while, the FEP was this really compelling

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framework, but there wasn't much direct experimental

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evidence to support it. Like it made sense theoretically,

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but it was hard to prove that this was actually

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how brains were working at a fundamental level.

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Yeah, you need that real -world validation. Exactly.

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And that's where this amazing research out of

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the Riken Research Institute in Japan comes in.

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They actually managed to get some really solid

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experimental proof for the SEP. It was a groundbreaking

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study. Totally. So, like, tell us more about

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the study. What did they actually do? Well, they

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started by creating these miniature controlled

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networks of neurons using cells from rat embryos.

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Essentially, they were working with these tiny,

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simplified versions of brains in a dish. Wow,

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that's wild. It is, right. And then, they delivered

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these patterns of electrical stimulation that

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were designed to mimic auditory sensations. Like,

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imagine you're listening to two different speakers

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talking at the same time. That kind of complex,

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mixed audio signal. They replicated that for

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these little neuron networks. So it was like

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they created a miniature, simplified version

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of a noisy environment for these brain cell cultures.

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Exactly. And initially, the networks reacted

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kind of randomly, which is what you'd expect

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from a system that's just starting to form and

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hasn't learned anything yet. But then, over time,

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something really remarkable happened. What happened?

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These initially chaotic networks started to self

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-organize. They began to selectively respond

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to one of the simulated speakers or the other,

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filtering out the noise from the other speaker.

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It was as if they were learning to tune into

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a single voice in a crowded room, just like we

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were talking about earlier. So they were actually

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able to separate out those mixed sensory signals

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and identify the likely sources, even though

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they'd never encountered anything like that before.

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Exactly. And the most compelling part, this self

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-organization wasn't just random. The researchers

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compared the way these biological networks structure

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themselves To computer models that were based

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on the free energy principle and guess what a

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match they matched perfectly The biological networks

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were organizing themselves in a way that was

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completely consistent with the predictions made

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by the FEP based computer models They essentially

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reverse engineered the computational models that

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these living neuronal networks seemed to be implicitly

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using. It was like they had cracked the code

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of how these networks were learning and adapting.

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So they could actually predict how the learning

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would unfold just by applying the free energy

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principle. Precisely. And they also saw that

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the mismatches between the network's internal

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state, its expectations, and the incoming sensory

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data were causing changes at the synaptic level.

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the connections between neurons. These synaptic

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changes were essentially fine -tuning the network's

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internal model of the world, making it better

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at predicting what was going to happen next.

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So it was this constant feedback loop, right?

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Prediction, error, update, repeat. Exactly. And

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they didn't stop there. They wanted to test the

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theory even further. So they used these special

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drugs to temporarily change the activity of the

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neurons. They could make them either more or

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less likely to fire kind of mess of their normal

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functioning a bit. And what happened when they

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did that? Well, the FEP predicted that these

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changes would affect the learning process in

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a very specific way, and that's exactly what

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they observed. By disrupting the network's internal

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models, they could actually control how the learning

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process unfolded. It was like providing even

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stronger evidence that the FEP was indeed the

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guiding principle behind how these networks were

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learning. So it's not just a theoretical concept,

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it's actually how real brains work. Precisely.

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And one of the lead researchers on the project,

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Takuya Isomura, put it really well. He said,

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I'm quoting here, our results suggest that the

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free energy principle is the self -organizing

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principle of biological neural networks. That's

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a pretty powerful statement. It is. And it has

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huge implications, not just for understanding

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our own brains, but also for the future of AI.

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Absolutely. Because if we can figure out how

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to build AI systems that learn and adapt in the

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same way that our brains do, using these principles

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of the FEP, that could be a real game changer.

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It could. And you know, Dr. Friston, the guy

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who came up with the FEP, is actually the chief

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scientist at a company called Versus AI. And

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they're doing some really fascinating work in

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this area. They're developing what's called Active

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Inference AI. So active inference AI, how is

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that different from the kind of AI that we're

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used to hearing about, like machine learning

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and all that? Well, traditional AI is very data

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-driven. You need these massive data sets to

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train the algorithms. And it can be really computationally

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expensive. Active inference AI, on the other

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hand, is inspired by how biological systems learn.

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It's all about using Bayesian inference, like

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our brains do, to constantly update and refine

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internal models of the world. So it's not just

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about passively processing data. It's about actively

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making predictions and learning from the results.

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Exactly. And it's much more efficient, too. Active

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inference AI systems can learn from much smaller

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amounts of data, and they can adapt to new situations

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more quickly. It's like they're more curious,

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more proactive in their learning. In a way, yes.

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They're not just waiting to be fed information.

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They're actively seeking it out and testing their

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predictions against the world. And that's a big

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part of why people are so excited about the potential

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of active inference AI. So, you know, we've talked

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a lot about these internal models that our brains

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create, but how does that actually work in practice?

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Like, what does an internal model even look like?

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That's a great question. And it's one that researchers

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are still trying to fully understand. But we

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can think of an internal model as a kind of simplified

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representation of the world. It captures the

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relationships between different things, the causes

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and effects, the patterns and regularities, and

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it allows us to make predictions about what's

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going to happen next, even in new and unfamiliar

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situations. So like, if I see a ball rolling

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towards me, my internal model of physics tells

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me that it's going to keep rolling unless something

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stops it. Exactly. And your internal model allows

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you to predict where the ball is going to go,

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how fast it's going to be moving, and even what's

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going to happen if you try to catch it. So these

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internal models are what allow us to navigate

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the world, make decisions, and plan for the future.

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Precisely. And that's what makes the free energy

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principle so powerful. It provides a unifying

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framework for understanding all sorts of different

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cognitive processes, from perception to learning

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to decision -making. And it also has huge implications

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for AI, because if we can build AI systems that

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have these sophisticated internal models, they'll

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be able to do so much more than just pattern

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recognition. They'll be able to actually understand

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the world, reason about it, and make intelligent

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decisions. Exactly. And that's why this recent

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experimental validation of the FEP is so significant.

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It suggests that we're on the right track. We're

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starting to understand the fundamental principles

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that underlie intelligence. And we're starting

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to build AI systems that are inspired by those

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principles. It's a really exciting time to be

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following this field. And for our listeners who

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want to dive deeper into this, there are some

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great resources available online. Versus AI,

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the company that Dr. Friston is involved with,

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has a really informative website. You can find

00:12:07.399 --> 00:12:10.600
them at versus .ai. And for those interested

00:12:10.600 --> 00:12:12.639
in the broader context of how this might all

00:12:12.639 --> 00:12:15.100
fit together in the future, the Spatial Web Foundation

00:12:15.100 --> 00:12:17.860
is doing some really interesting work on creating

00:12:17.860 --> 00:12:20.740
this kind of shared, intelligent digital space,

00:12:21.000 --> 00:12:23.539
a sort of metaverse for AI. You can check them

00:12:23.539 --> 00:12:26.320
out at spatialwebfoundation .org. And Denise

00:12:26.320 --> 00:12:28.519
Holt, she's got this awesome blog where she breaks

00:12:28.519 --> 00:12:31.200
down all these complex AI concepts in a way that's

00:12:31.200 --> 00:12:33.080
really easy to understand. You can find her at

00:12:33.080 --> 00:12:36.320
DeniseHolt .us. Oh, fantastic resources. So I

00:12:36.320 --> 00:12:38.139
guess the big question that this all leaves us

00:12:38.139 --> 00:12:40.440
with is, if our brains are essentially prediction

00:12:40.440 --> 00:12:43.500
machines, constantly shaping our perception of

00:12:43.500 --> 00:12:46.289
reality based on our internal models, What does

00:12:46.289 --> 00:12:48.850
that say about the nature of reality itself?

00:12:49.129 --> 00:12:51.649
Like, is reality even objective or is it just

00:12:51.649 --> 00:12:53.809
a construction of our own minds? It's a deep

00:12:53.809 --> 00:12:55.730
philosophical question and one that I don't think

00:12:55.730 --> 00:12:58.529
we have a definitive answer to yet. But I think

00:12:58.529 --> 00:13:01.210
the free energy principle gives us a really interesting

00:13:01.210 --> 00:13:04.490
new perspective on this whole debate. It suggests

00:13:04.490 --> 00:13:07.350
that the reality we experience is, at least in

00:13:07.350 --> 00:13:10.470
part, a product of our own expectations and predictions.

00:13:10.809 --> 00:13:12.570
And it's a pretty mind blowing idea to think

00:13:12.570 --> 00:13:14.850
about. It really is. Thanks for joining us on

00:13:14.850 --> 00:13:16.769
this deep dive into the free energy principle.

00:13:17.149 --> 00:13:19.549
Until next time, keep those brains predicting.
