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Welcome to the deep dive.

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We're diving into AI and medicine today,

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especially its potential for creating new treatments.

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You've given us some really interesting stuff to work with,

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a transcript from a Harvard Medical School seminar

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on AI and medicine, and then some research excerpts

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on, well, algorithmic bias.

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So let's unpack this,

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we'll pull out the important bits from all this,

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look at some surprising real world examples,

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and by the end, to be left with a question

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to really chew on, hopefully, sound good.

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Sounds great.

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Perfect.

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So let's jump right in.

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The potential of AI for discovering new treatments,

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that's where we'll start.

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Yeah, I mean, AI is already having a bay impact

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on how we treat patients,

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and it's only gonna get bigger from here.

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I was really struck by that story in the seminar

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about a six year old child.

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This kid just suddenly loses the ability to walk and talk.

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Oh, wow.

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Like it sounds like a movie plot,

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that this really happened.

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Yeah, absolutely.

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Imagine how desperate the parents were.

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I mean, doctor after doctor,

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and nobody could figure out what was wrong.

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Thankfully, they were able to get into this program

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called the Undiagnosed Disease Network.

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And this network, they use AI to analyze

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millions of genetic records,

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looking for anything that could explain,

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you know, explain what was happening to this child.

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Wow.

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And in this case, the AI was able to pinpoint

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a rare gene mutation as the cause.

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So it's like AI found the needle in the haystack.

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Right.

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And here's the really wild part.

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Just by making a simple change to the child's diet,

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again identified through AI,

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they were able to regain the ability to walk and talk.

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It's amazing, right?

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It's mind blowing.

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It's like, yeah, AI can tackle

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those really complex, difficult cases.

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Right.

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But it's also changing how we approach everyday healthcare.

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Absolutely.

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I think one really good example of that is,

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you know, that smartphone app that was developed

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to diagnose melanoma from skin images.

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Like early detection of melanoma is so critical.

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Right.

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And we have AI that's putting that power

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right in our pockets.

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Right.

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Okay.

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So moving on, the seminar also talked about

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how AI can help us make the best use of existing drugs.

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It's kind of like we have this huge medicine cabinet,

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but sometimes we just don't know

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which medicine to take, right?

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Absolutely.

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AI can really help with that.

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By analyzing data like gene expression patterns

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and, you know, patient histories,

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AI can identify treatment options

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that might not be obvious to human doctors.

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Right.

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And we had this amazing story in the seminar

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about a teenager with severe ulcerative colitis.

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I mean, nothing was working.

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Oh, wow.

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And this poor kid was facing a colectomy,

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which is major surgery.

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Right.

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Awful.

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So a team of computer scientists got involved.

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Yes.

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Started analyzing the patient's gene expression data.

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Okay, I have to guess.

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Okay.

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Was it essential oils?

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No, not quite.

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Okay.

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It turned out that a treatment derived from indigo, you know.

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Why?

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Like the dye.

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The dye?

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Yeah, indigo.

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It has anti-inflammatory properties.

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That's amazing.

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Who would have thought?

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I know.

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It's really cool.

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Indigo, the dye.

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So it might seem counterintuitive, but it worked.

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The teenager avoided surgery

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and they've been in remission for three years now.

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So it's like AI is all about connecting the dots,

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sometimes in ways that we just wouldn't think of.

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Right.

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Which is what makes it so powerful.

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Absolutely.

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It's not just medication though, right?

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It can actually help us refine surgical techniques.

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Totally.

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And the seminar talked about a study on AI-assisted suturing.

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This was in pigs.

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Okay.

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And the AI actually helped make the suturing

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much more precise, which led to better overall outcomes.

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So you're thinking robot surgeons in the future?

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Potentially, yeah.

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That's wild, okay.

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But with all this amazing potential,

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I mean, I can't help but think about the downsides too.

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What about those biases that we always hear about with AI?

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Yeah.

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I mean, it's really important to understand that AI systems,

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they learn from the data that they are given.

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And if that data reflects societal biases,

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then the AI system might perpetuate them, unfortunately.

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So if there are already disparities in healthcare,

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the AI could unintentionally make those disparities worse.

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That's right.

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Think about something like maternal mortality rates,

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which are already significantly higher

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for certain demographics.

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Right.

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If an AI is trained on data that reflects those disparities,

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then it might not recommend the best course of treatment

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for everyone equally.

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So it's like the AI is inheriting the same biases

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that already exist in the real world.

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Exactly.

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That's unsettling.

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And we also need to consider representation

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in genetic studies and clinical trials.

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Right.

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Because if certain populations are underrepresented

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in that data, then the AI might not be as effective for them.

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Yeah.

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So it's not just about developing the AI,

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it's about making sure that it's trained on data

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that's truly representative of everyone.

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Absolutely.

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If we want AI to benefit all of us,

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it needs to learn from a data set

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that's diverse and inclusive.

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And the research you provided,

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it actually included some real world examples

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that really drive this point home,

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like that New Zealand passport photo algorithm.

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Oh yeah.

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There was that case where it failed

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to recognize a man's open eyes.

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Probably because the training data

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didn't include enough images

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of people from his ethnicity.

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That's so frustrating.

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Like imagine being told that your eyes aren't open

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when they clearly are, just because a computer program

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doesn't recognize your face properly.

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Right.

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It can have real world impacts.

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And there was that other case with,

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you know, a recidivism prediction algorithm

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that was used in the justice system.

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Yeah.

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And it turned out that it was assigning

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higher risk scores to black defendants.

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Wow.

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Even if they didn't reoffend compared to white defendants

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with similar histories.

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That's a little scary.

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It really emphasizes the need to,

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to not just blindly trust these AI systems.

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Right.

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Without, without understanding their limitations

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because the consequences can be, can be really serious.

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Yeah. Absolutely.

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AI is a powerful tool.

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Yeah.

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But like any tool, it can be misused.

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So how do we, how do we ensure that AI and medicine

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is used ethically and for the good of everyone?

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Well, it really starts with how we design

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and train these systems.

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We need to make sure that they're trained on data

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that is diverse and representative.

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And we need to be very aware of the potential for bias.

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It's almost like raising a child, right?

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You have to, you have to teach them the right values.

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You have to make sure that they're exposed to,

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to a wide range of experiences.

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That's a great analogy.

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Yeah.

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Like we need to be just as careful

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about the information that we feed these AI systems

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as we are about the information that we give,

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you know, to our children.

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And we need to be vigilant.

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Mm-hmm.

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Right?

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We can't just assume that AI is gonna solve

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all our problems without creating any new ones.

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Exactly.

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AI is a powerful tool, but it's not a magic bullet.

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Right.

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It's not a test to use it wisely and responsibly.

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So I'm curious, like what are some specific things

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that we can do to mitigate bias

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and ensure that AI is being used for good in medicine?

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Well, I think one crucial step is carefully

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framing the problem for the AI.

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Like we need to be incredibly clear

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about what we're asking the AI to do

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and make sure that its goals really align

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with our ethical considerations.

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Like imagine you're giving instructions to someone.

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Like when I order my coffee.

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Okay.

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And then we need to be very specific.

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Exactly.

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We have to be just as precise when we're instructing AI,

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making sure it understands our priorities

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and that it doesn't inadvertently produce biased outcomes.

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So, you know, we've talked about the importance

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of diverse and representative training data.

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Right.

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Which, you know, it's kind of like how clinical trials

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need to have a variety of participants.

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Absolutely.

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It's all about reflecting the real world.

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Right.

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Not just the narrow sliver of it.

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And then there's this other really interesting aspect

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using AI to actually detect and quantify bias itself.

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Oh, interesting.

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Yeah.

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Like we can analyze how an algorithm's output changes

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when we, you know, tweak factors like race or gender.

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And that can help us pinpoint potential biases.

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So we can actually use AI to fight against bias.

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Right. Exactly.

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That's incredible.

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Yeah.

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It's just the beginning.

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And as AI continues to evolve,

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we're going to find even more ways

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to ensure its ethical and responsible use.

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This has been really eye-opening conversation.

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And we've only just scratched the surface.

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But before we jump into part two,

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I want to leave our listeners with something to think about.

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Imagine that there's a highly accurate AI melanoma detection

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app available right now.

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Uh-huh.

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Would you use it?

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If not, why?

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What factors would influence your decision?

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That's a great question.

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It really gets to the heart of this whole idea

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of how we balance technological advancement

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with personal agency and trust in medical AI.

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And, you know, there are no easy answers,

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but it's definitely a conversation worth having.

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Definitely.

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We'll be back with part two soon.

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We'll delve even deeper into other exciting aspects

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of AI and medicine.

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So stay tuned.

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Back again for more of the deep dive.

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So we're really getting into it now,

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00:08:51,080 --> 00:08:53,400
exploring the potential of AI and medicine.

281
00:08:53,400 --> 00:08:55,480
And one thing that stood out in that Harvard seminar

282
00:08:55,480 --> 00:08:58,720
transcript, it was how the role of doctors

283
00:08:58,720 --> 00:09:00,960
is going to change in this future with AI.

284
00:09:00,960 --> 00:09:04,880
I mean, are we going to see, like, robot doctors anytime soon?

285
00:09:04,880 --> 00:09:06,640
Well, that's the question everybody's asking.

286
00:09:06,640 --> 00:09:10,400
But the seminar really emphasized that AI is,

287
00:09:10,400 --> 00:09:12,960
it's more like a highly skilled assistant, you know?

288
00:09:12,960 --> 00:09:13,960
Right.

289
00:09:13,960 --> 00:09:17,560
It's really about augmenting doctors' abilities,

290
00:09:17,560 --> 00:09:19,880
not necessarily replacing them entirely.

291
00:09:19,880 --> 00:09:20,380
OK.

292
00:09:20,380 --> 00:09:22,480
So think of it more as a powerful tool that

293
00:09:22,480 --> 00:09:25,160
helps doctors do their jobs even better.

294
00:09:25,160 --> 00:09:27,880
So like a super-powered sidekick for doctors.

295
00:09:27,880 --> 00:09:28,760
Exactly.

296
00:09:28,760 --> 00:09:30,680
OK, that makes me feel a little bit better.

297
00:09:30,680 --> 00:09:33,800
But in what ways, like, what are some specific ways

298
00:09:33,800 --> 00:09:37,000
that this sidekick could actually change how doctors work?

299
00:09:37,000 --> 00:09:41,560
Well, imagine if AI could handle all of those data-heavy tasks.

300
00:09:41,560 --> 00:09:45,720
You know, pulling up relevant research, analyzing lab results,

301
00:09:45,720 --> 00:09:48,640
even suggesting potential diagnoses based on a patient

302
00:09:48,640 --> 00:09:51,280
symptoms that would free up doctors to really focus

303
00:09:51,280 --> 00:09:54,320
on what they do best, which is interacting with patients,

304
00:09:54,320 --> 00:09:56,240
applying their years of experience,

305
00:09:56,240 --> 00:09:58,080
making those nuanced decisions.

306
00:09:58,080 --> 00:10:00,160
So it's like having a super-efficient research

307
00:10:00,160 --> 00:10:02,240
assistant who can just instantly give you all

308
00:10:02,240 --> 00:10:03,240
the information you need.

309
00:10:03,240 --> 00:10:03,740
Exactly.

310
00:10:03,740 --> 00:10:05,680
So you can spend more time actually talking

311
00:10:05,680 --> 00:10:07,880
to the patient, understanding their concerns.

312
00:10:07,880 --> 00:10:08,360
Right.

313
00:10:08,360 --> 00:10:10,280
That personalized approach is really key.

314
00:10:10,280 --> 00:10:13,160
It helps us move away from that one-size-fits-all model

315
00:10:13,160 --> 00:10:13,720
of medicine.

316
00:10:13,720 --> 00:10:14,320
Right.

317
00:10:14,320 --> 00:10:16,080
And toward a more tailored approach,

318
00:10:16,080 --> 00:10:18,800
where treatments are really designed for each patient's

319
00:10:18,800 --> 00:10:20,560
unique circumstances and needs.

320
00:10:20,560 --> 00:10:22,160
And that actually reminds us of the story

321
00:10:22,160 --> 00:10:24,520
we were talking about earlier about the teenager

322
00:10:24,520 --> 00:10:26,120
with ulcerative colitis.

323
00:10:26,120 --> 00:10:29,280
Like, the AI didn't just spit out a general treatment

324
00:10:29,280 --> 00:10:30,280
recommendation.

325
00:10:30,280 --> 00:10:33,680
It actually analyzed that patient's specific gene

326
00:10:33,680 --> 00:10:37,400
expression data to figure out what was going to work for them.

327
00:10:37,400 --> 00:10:37,720
Yeah.

328
00:10:37,720 --> 00:10:39,800
And that's just the, I mean, that's one example.

329
00:10:39,800 --> 00:10:40,200
Yeah.

330
00:10:40,200 --> 00:10:41,400
Think about drug development.

331
00:10:41,400 --> 00:10:45,200
Like, AI can identify subgroups of patients

332
00:10:45,200 --> 00:10:49,440
who are most likely to benefit from a particular medication,

333
00:10:49,440 --> 00:10:52,280
even if those medications weren't effective in larger,

334
00:10:52,280 --> 00:10:54,240
more general trials.

335
00:10:54,240 --> 00:10:57,520
So that has huge implications for how we design and test

336
00:10:57,520 --> 00:10:58,320
new therapies.

337
00:10:58,320 --> 00:11:01,040
So instead of spending years and millions of dollars

338
00:11:01,040 --> 00:11:03,720
on drug trials that ultimately might not work,

339
00:11:03,720 --> 00:11:07,120
you could actually use AI to target those trials more

340
00:11:07,120 --> 00:11:09,160
effectively and bring life-saving medications

341
00:11:09,160 --> 00:11:10,240
to people faster.

342
00:11:10,240 --> 00:11:11,160
Exactly.

343
00:11:11,160 --> 00:11:11,720
Yeah.

344
00:11:11,720 --> 00:11:13,840
It's really, it's really amazing what it can do.

345
00:11:13,840 --> 00:11:15,920
And it's not just drug development.

346
00:11:15,920 --> 00:11:19,280
The seminar also talked about how AI can help doctors

347
00:11:19,280 --> 00:11:22,480
stay up to date, you know, with this ever-growing mountain

348
00:11:22,480 --> 00:11:23,600
of medical knowledge.

349
00:11:23,600 --> 00:11:24,720
I can imagine.

350
00:11:24,720 --> 00:11:26,360
Keeping up with all the latest research,

351
00:11:26,360 --> 00:11:28,560
it must feel like drinking from a fire hose.

352
00:11:28,560 --> 00:11:30,080
It really is, yeah.

353
00:11:30,080 --> 00:11:32,360
So AI can kind of act as a filter.

354
00:11:32,360 --> 00:11:32,800
OK.

355
00:11:32,800 --> 00:11:35,080
For that fire hose of information,

356
00:11:35,080 --> 00:11:37,040
highlighting the most relevant studies,

357
00:11:37,040 --> 00:11:40,440
flagging new developments that might impact a doctor's practice.

358
00:11:40,440 --> 00:11:42,600
So it's like having a personalized medical journal.

359
00:11:42,600 --> 00:11:43,240
That's pretty cool.

360
00:11:43,240 --> 00:11:44,960
It would save doctors so much time.

361
00:11:44,960 --> 00:11:45,360
Right.

362
00:11:45,360 --> 00:11:46,840
And it would help ensure that they're not

363
00:11:46,840 --> 00:11:47,960
missing out on anything important.

364
00:11:47,960 --> 00:11:49,200
Yeah, absolutely.

365
00:11:49,200 --> 00:11:49,560
OK.

366
00:11:49,560 --> 00:11:51,760
So it all sounds pretty amazing.

367
00:11:51,760 --> 00:11:56,480
But I know there are also concerns about the potential

368
00:11:56,480 --> 00:11:58,840
downsides of AI in medicine.

369
00:11:58,840 --> 00:11:59,680
What are those?

370
00:11:59,680 --> 00:12:00,080
Yeah.

371
00:12:00,080 --> 00:12:03,160
Well, of course, we have to be aware of those potential pitfalls.

372
00:12:03,160 --> 00:12:06,600
I think one concern is the risk of overreliance on AI,

373
00:12:06,600 --> 00:12:08,480
you know, where doctors might start seeing it

374
00:12:08,480 --> 00:12:11,680
as the sort of magical solution to every medical problem.

375
00:12:11,680 --> 00:12:15,040
And they might start losing their critical thinking skills.

376
00:12:15,040 --> 00:12:15,440
Right.

377
00:12:15,440 --> 00:12:17,360
So it's important to remember that it's a tool.

378
00:12:17,360 --> 00:12:18,080
Yes.

379
00:12:18,080 --> 00:12:19,800
Not a replacement for human judgment.

380
00:12:19,800 --> 00:12:20,480
Exactly.

381
00:12:20,480 --> 00:12:21,280
And expertise.

382
00:12:21,280 --> 00:12:24,720
Yeah, it's like relying solely on your GPS navigation.

383
00:12:24,720 --> 00:12:25,200
Right.

384
00:12:25,200 --> 00:12:25,680
Yeah.

385
00:12:25,680 --> 00:12:28,320
It might get you to your destination most of the time,

386
00:12:28,320 --> 00:12:30,360
but you still need to be able to think for yourself

387
00:12:30,360 --> 00:12:32,360
and figure out alternative routes

388
00:12:32,360 --> 00:12:35,920
if the GPS sends you down a dead end street.

389
00:12:35,920 --> 00:12:37,280
That's a good analogy.

390
00:12:37,280 --> 00:12:41,520
I also worry about AI negatively impacting

391
00:12:41,520 --> 00:12:43,200
that doctor-patient relationship.

392
00:12:43,200 --> 00:12:43,680
Right.

393
00:12:43,680 --> 00:12:47,080
Which is, I mean, so much of it is built on trust and empathy.

394
00:12:47,080 --> 00:12:47,720
Yeah.

395
00:12:47,720 --> 00:12:50,080
And I feel like if patients start to feel like they're

396
00:12:50,080 --> 00:12:54,200
interacting more with a machine than with a human,

397
00:12:54,200 --> 00:12:56,520
that that could really erode that bond of trust.

398
00:12:56,520 --> 00:12:57,640
It's a valid concern.

399
00:12:57,640 --> 00:12:59,160
But you know, I think AI can also

400
00:12:59,160 --> 00:13:01,040
be used to enhance that relationship.

401
00:13:01,040 --> 00:13:02,440
Because if doctors have more time,

402
00:13:02,440 --> 00:13:04,680
they can actually spend more time with their patients

403
00:13:04,680 --> 00:13:06,480
really listening to their concerns.

404
00:13:06,480 --> 00:13:08,320
So it really comes down to how we use it.

405
00:13:08,320 --> 00:13:08,720
Right.

406
00:13:08,720 --> 00:13:11,160
It can be a powerful tool for good.

407
00:13:11,160 --> 00:13:13,480
But it's up to us to make sure it's

408
00:13:13,480 --> 00:13:16,840
being used in a way that benefits both doctors and patients.

409
00:13:16,840 --> 00:13:17,600
Exactly.

410
00:13:17,600 --> 00:13:19,840
It's about striking that balance, you know,

411
00:13:19,840 --> 00:13:22,920
between technological advancement and that human

412
00:13:22,920 --> 00:13:24,280
touch in medicine.

413
00:13:24,280 --> 00:13:26,160
And speaking of human touch, I mean,

414
00:13:26,160 --> 00:13:29,560
we can't ignore the issue of access and equity.

415
00:13:29,560 --> 00:13:30,160
Right.

416
00:13:30,160 --> 00:13:33,760
AI-powered health care needs to be accessible to everyone.

417
00:13:33,760 --> 00:13:34,360
Absolutely.

418
00:13:34,360 --> 00:13:37,840
Regardless of their socioeconomic status or their background.

419
00:13:37,840 --> 00:13:38,840
Yeah.

420
00:13:38,840 --> 00:13:41,640
We need to be mindful of those potential disparities

421
00:13:41,640 --> 00:13:44,800
and work towards a future where everyone benefits

422
00:13:44,800 --> 00:13:48,320
from the incredible potential of AI in medicine.

423
00:13:48,320 --> 00:13:53,360
It's about making sure that AI serves humanity as a whole,

424
00:13:53,360 --> 00:13:54,880
not just a privileged few.

425
00:13:54,880 --> 00:13:55,480
Absolutely.

426
00:13:55,480 --> 00:13:57,720
And I think we need to talk about regulation and oversight

427
00:13:57,720 --> 00:13:58,360
as well.

428
00:13:58,360 --> 00:14:01,400
As AI becomes more integrated into health care,

429
00:14:01,400 --> 00:14:04,080
we need to make sure that we have robust frameworks in place

430
00:14:04,080 --> 00:14:05,960
to ensure that these systems are safe,

431
00:14:05,960 --> 00:14:08,120
that they're effective, that they're being used ethically.

432
00:14:08,120 --> 00:14:10,520
It's a complex, constantly evolving field.

433
00:14:10,520 --> 00:14:11,800
We can't be complacent.

434
00:14:11,800 --> 00:14:14,080
So it's not just about developing the technology.

435
00:14:14,080 --> 00:14:16,760
It's about making sure we use it responsibly.

436
00:14:16,760 --> 00:14:19,360
And I think that leads to one of the biggest questions that

437
00:14:19,360 --> 00:14:21,200
was raised in the seminar, which is,

438
00:14:21,200 --> 00:14:23,240
who's accountable when AI goes wrong?

439
00:14:23,240 --> 00:14:26,760
If an AI system makes a mistake that harms a patient,

440
00:14:26,760 --> 00:14:27,880
who do we blame?

441
00:14:27,880 --> 00:14:29,720
That's the million dollar question, right?

442
00:14:29,720 --> 00:14:32,960
It's such a tangled web of responsibility.

443
00:14:32,960 --> 00:14:34,680
You have the doctor, the developer, the hospital.

444
00:14:34,680 --> 00:14:35,600
They all play a role.

445
00:14:35,600 --> 00:14:40,440
It's a really complex issue that legal scholars and ethicists

446
00:14:40,440 --> 00:14:42,320
are really grappling with right now.

447
00:14:42,320 --> 00:14:43,920
It reminds me of all those discussions

448
00:14:43,920 --> 00:14:45,320
about self-driving cars.

449
00:14:45,320 --> 00:14:45,840
Right.

450
00:14:45,840 --> 00:14:47,760
Like if a self-driving car gets into an accident,

451
00:14:47,760 --> 00:14:48,440
who's at fault?

452
00:14:48,440 --> 00:14:48,940
Right.

453
00:14:48,940 --> 00:14:53,040
The passenger, the manufacturer, the software developer.

454
00:14:53,040 --> 00:14:55,120
It's a similar dilemma.

455
00:14:55,120 --> 00:14:55,520
Exactly.

456
00:14:55,520 --> 00:14:58,280
And in health care, the stakes are obviously even higher.

457
00:14:58,280 --> 00:14:58,560
Right.

458
00:14:58,560 --> 00:15:01,680
Because we're talking about people's lives and well-being.

459
00:15:01,680 --> 00:15:03,360
So what can we do?

460
00:15:03,360 --> 00:15:06,760
How do we ensure accountability, protect patients

461
00:15:06,760 --> 00:15:10,280
in this new era of AI-driven medicine?

462
00:15:10,280 --> 00:15:11,960
Well, I think we need to be proactive.

463
00:15:11,960 --> 00:15:15,400
Like, rigorous testing and validation of AI systems,

464
00:15:15,400 --> 00:15:17,800
are they're ever used in a clinical setting?

465
00:15:17,800 --> 00:15:20,640
And having clear lines of responsibility and legal

466
00:15:20,640 --> 00:15:23,720
frameworks to address any unintended consequences,

467
00:15:23,720 --> 00:15:25,080
I think that's really important.

468
00:15:25,080 --> 00:15:27,160
It sounds like we're in uncharted territory here.

469
00:15:27,160 --> 00:15:27,880
We are.

470
00:15:27,880 --> 00:15:29,600
But that makes it all the more important

471
00:15:29,600 --> 00:15:31,560
to be having these conversations now.

472
00:15:31,560 --> 00:15:34,600
Before AI becomes so deeply integrated into health care

473
00:15:34,600 --> 00:15:36,680
that it's too late to sort of course correct.

474
00:15:36,680 --> 00:15:37,320
Right.

475
00:15:37,320 --> 00:15:40,960
We need to make sure that AI is used responsibly

476
00:15:40,960 --> 00:15:42,920
and that patients are protected.

477
00:15:42,920 --> 00:15:46,200
And that includes being transparent with patients,

478
00:15:46,200 --> 00:15:46,880
right?

479
00:15:46,880 --> 00:15:48,280
Letting them know how these systems work,

480
00:15:48,280 --> 00:15:50,560
giving them a voice in their own care.

481
00:15:50,560 --> 00:15:51,880
Absolutely, yeah.

482
00:15:51,880 --> 00:15:54,040
Transparency and trust are essential

483
00:15:54,040 --> 00:15:57,560
for any kind of successful integration of AI

484
00:15:57,560 --> 00:15:58,680
into health care.

485
00:15:58,680 --> 00:16:01,120
This deep dive is really highlighting just how much

486
00:16:01,120 --> 00:16:03,120
there is to consider.

487
00:16:03,120 --> 00:16:06,120
AI has the potential to revolutionize medicine.

488
00:16:06,120 --> 00:16:09,240
But we have to approach it thoughtfully, ethically,

489
00:16:09,240 --> 00:16:11,960
with this human-centered focus.

490
00:16:11,960 --> 00:16:13,480
So what else did the seminar talk about?

491
00:16:13,480 --> 00:16:15,520
Well, it also raised this really fascinating question

492
00:16:15,520 --> 00:16:18,560
of how AI might actually change the very definition of what

493
00:16:18,560 --> 00:16:19,800
it means to be a doctor.

494
00:16:19,800 --> 00:16:20,800
Oh, that's interesting.

495
00:16:20,800 --> 00:16:24,080
So as AI takes on more of those tasks that doctors

496
00:16:24,080 --> 00:16:27,720
traditionally do, what does it mean to be a doctor?

497
00:16:27,720 --> 00:16:32,960
Like if AI can diagnose diseases and even perform surgery,

498
00:16:32,960 --> 00:16:34,440
what's left for the humans to do?

499
00:16:34,440 --> 00:16:36,000
That's the big question.

500
00:16:36,000 --> 00:16:38,400
And there's no easy answers.

501
00:16:38,400 --> 00:16:40,840
But the seminar suggested that maybe

502
00:16:40,840 --> 00:16:44,200
the role of the doctor might evolve to focus more

503
00:16:44,200 --> 00:16:48,080
on guiding and counseling and advocating for patients.

504
00:16:48,080 --> 00:16:53,160
It's about embracing those uniquely human qualities

505
00:16:53,160 --> 00:16:56,000
of empathy and communication and understanding

506
00:16:56,000 --> 00:16:58,720
a patient's individual needs and values.

507
00:16:58,720 --> 00:17:02,160
So even in a world of AI-driven health care,

508
00:17:02,160 --> 00:17:05,400
that human connection is still at the heart of it all.

509
00:17:05,400 --> 00:17:07,520
That's the key takeaway.

510
00:17:07,520 --> 00:17:09,480
AI is this powerful tool, but it's

511
00:17:09,480 --> 00:17:11,600
up to us to use it in a way that really

512
00:17:11,600 --> 00:17:14,560
complements and enhances that human element of health care,

513
00:17:14,560 --> 00:17:15,440
not replace it.

514
00:17:15,440 --> 00:17:17,400
This has been such a thought-provoking conversation,

515
00:17:17,400 --> 00:17:19,200
but I feel like we've just scratched the surface.

516
00:17:19,200 --> 00:17:19,760
I know.

517
00:17:19,760 --> 00:17:20,800
What's coming up in part three?

518
00:17:20,800 --> 00:17:22,800
Well, in part three, we're going to shift gears a bit

519
00:17:22,800 --> 00:17:25,960
and delve into that groundbreaking research

520
00:17:25,960 --> 00:17:28,680
that you provided on AI's potential

521
00:17:28,680 --> 00:17:31,760
to unlock new treatments and therapies,

522
00:17:31,760 --> 00:17:34,520
taking personalized medicine to a whole new level.

523
00:17:34,520 --> 00:17:35,520
Ooh, can't wait.

524
00:17:35,520 --> 00:17:37,520
Sounds exciting.

525
00:17:37,520 --> 00:17:39,000
All right, we're back for the final part

526
00:17:39,000 --> 00:17:41,920
of our deep dive into AI in medicine.

527
00:17:41,920 --> 00:17:44,120
And this time, we're zeroing in on something

528
00:17:44,120 --> 00:17:46,280
I know you're particularly interested in,

529
00:17:46,280 --> 00:17:49,360
this cutting-edge research into AI's potential

530
00:17:49,360 --> 00:17:51,520
for developing new treatments and therapies.

531
00:17:51,520 --> 00:17:52,800
Yeah, it's an area that's really

532
00:17:52,800 --> 00:17:55,320
generating a lot of excitement, both among researchers

533
00:17:55,320 --> 00:17:56,280
and clinicians.

534
00:17:56,280 --> 00:17:58,480
I've been going through those research excerpts you sent,

535
00:17:58,480 --> 00:18:00,760
and I've got to say, I'm pretty blown away

536
00:18:00,760 --> 00:18:01,920
by the possibilities.

537
00:18:01,920 --> 00:18:05,560
AI is already changing how we approach drug discovery

538
00:18:05,560 --> 00:18:07,400
and treatment development, and we're really just

539
00:18:07,400 --> 00:18:08,200
at the beginning.

540
00:18:08,200 --> 00:18:09,800
One thing that really struck me was just

541
00:18:09,800 --> 00:18:13,040
how AI can analyze massive amounts of data.

542
00:18:13,040 --> 00:18:15,880
We're talking everything from genetic information

543
00:18:15,880 --> 00:18:19,120
and clinical records to lifestyle factors.

544
00:18:19,120 --> 00:18:22,320
It's like having a whole team of super sleuths combing

545
00:18:22,320 --> 00:18:23,600
through mountains of evidence.

546
00:18:23,600 --> 00:18:24,320
Oh, well, but.

547
00:18:24,320 --> 00:18:25,880
Trying to crack the case of disease.

548
00:18:25,880 --> 00:18:27,400
Yeah, that's a great analogy.

549
00:18:27,400 --> 00:18:29,800
AI can identify these patterns and connections

550
00:18:29,800 --> 00:18:31,880
that humans might just completely miss,

551
00:18:31,880 --> 00:18:33,720
and that can lead to all sorts of new insights

552
00:18:33,720 --> 00:18:37,240
into the causes of disease and potential treatment avenues.

553
00:18:37,240 --> 00:18:41,720
I was particularly fascinated by the research on AI's role

554
00:18:41,720 --> 00:18:44,440
in developing new treatments for Alzheimer's.

555
00:18:44,440 --> 00:18:46,720
It seems like we've been hitting a wall with those traditional

556
00:18:46,720 --> 00:18:47,320
approaches.

557
00:18:47,320 --> 00:18:48,160
Yeah.

558
00:18:48,160 --> 00:18:51,840
But maybe AI is the key to unlocking some new breaksers.

559
00:18:51,840 --> 00:18:54,760
Alzheimer's is such a complex disease,

560
00:18:54,760 --> 00:18:58,480
and it has been really tough to develop effective treatments.

561
00:18:58,480 --> 00:19:00,840
But AI does offer some new hope.

562
00:19:00,840 --> 00:19:01,840
In what way?

563
00:19:01,840 --> 00:19:05,240
Well, AI can analyze brain imaging data,

564
00:19:05,240 --> 00:19:08,800
genetic profiles, cognitive test results, all of that

565
00:19:08,800 --> 00:19:11,720
to identify those early signs of Alzheimer's

566
00:19:11,720 --> 00:19:14,360
and even predict how the disease might progress.

567
00:19:14,360 --> 00:19:16,960
This could lead to interventions that could slow down

568
00:19:16,960 --> 00:19:19,520
or even prevent the onset of symptoms.

569
00:19:19,520 --> 00:19:22,360
So instead of waiting for the disease to really take hold,

570
00:19:22,360 --> 00:19:24,800
you could potentially intervene much earlier.

571
00:19:24,800 --> 00:19:25,280
Exactly.

572
00:19:25,280 --> 00:19:27,480
And maybe even change the trajectory of the disease

573
00:19:27,480 --> 00:19:28,200
entirely.

574
00:19:28,200 --> 00:19:28,880
That's the idea.

575
00:19:28,880 --> 00:19:30,960
And this isn't just limited to Alzheimer's either.

576
00:19:30,960 --> 00:19:34,000
AI is being applied to such a wide range of conditions.

577
00:19:34,000 --> 00:19:36,160
Everything from cancer and heart disease

578
00:19:36,160 --> 00:19:38,120
to rare genetic disorders.

579
00:19:38,120 --> 00:19:40,160
The research mentioned a case where AI

580
00:19:40,160 --> 00:19:43,280
was used to create a personalized cancer treatment.

581
00:19:43,280 --> 00:19:44,120
Oh, wow.

582
00:19:44,120 --> 00:19:46,360
Based on the patient's unique genetic profile,

583
00:19:46,360 --> 00:19:48,400
it's almost like having a drug that's

584
00:19:48,400 --> 00:19:49,640
tailor made just for you.

585
00:19:49,640 --> 00:19:51,760
Yeah, that's the promise of precision medicine, right?

586
00:19:51,760 --> 00:19:52,440
Right.

587
00:19:52,440 --> 00:19:55,520
Using AI to analyze a patient's tumor DNA,

588
00:19:55,520 --> 00:19:57,520
identify the specific mutations that

589
00:19:57,520 --> 00:19:59,600
are driving that cancer, and then predict

590
00:19:59,600 --> 00:20:02,040
which drugs are most likely to be effective.

591
00:20:02,040 --> 00:20:04,800
It's a completely different approach to cancer treatment.

592
00:20:04,800 --> 00:20:06,520
It sounds like something out of science fiction.

593
00:20:06,520 --> 00:20:06,920
I know.

594
00:20:06,920 --> 00:20:07,880
It's pretty incredible.

595
00:20:07,880 --> 00:20:09,000
But it's happening right now.

596
00:20:09,000 --> 00:20:09,400
It is.

597
00:20:09,400 --> 00:20:10,400
It's really happening.

598
00:20:10,400 --> 00:20:14,680
And AI is also revolutionizing drug discovery,

599
00:20:14,680 --> 00:20:17,880
helping us identify promising new compounds,

600
00:20:17,880 --> 00:20:21,200
speeding up the development of life-saving medications.

601
00:20:21,200 --> 00:20:22,800
I mean, traditionally, drug discovery

602
00:20:22,800 --> 00:20:25,160
has been such a long and expensive process.

603
00:20:25,160 --> 00:20:25,840
It really has.

604
00:20:25,840 --> 00:20:27,960
With no guarantee of success.

605
00:20:27,960 --> 00:20:29,640
But it seems like AI has the potential

606
00:20:29,640 --> 00:20:31,520
to completely change that.

607
00:20:31,520 --> 00:20:32,720
Think of it this way.

608
00:20:32,720 --> 00:20:34,960
AI can act like a virtual chemist.

609
00:20:34,960 --> 00:20:35,440
OK.

610
00:20:35,440 --> 00:20:38,480
Analyzing huge libraries of chemical compounds

611
00:20:38,480 --> 00:20:41,760
and predicting which ones might have therapeutic effects.

612
00:20:41,760 --> 00:20:44,600
So that could drastically reduce the time and cost

613
00:20:44,600 --> 00:20:46,000
of bringing new drugs to market.

614
00:20:46,000 --> 00:20:47,080
Yeah, potentially.

615
00:20:47,080 --> 00:20:49,440
That's incredible, making life-saving treatments

616
00:20:49,440 --> 00:20:51,480
available to patients so much sooner.

617
00:20:51,480 --> 00:20:52,640
It's really exciting.

618
00:20:52,640 --> 00:20:55,200
But we do need to proceed with caution.

619
00:20:55,200 --> 00:20:58,160
We need to ensure that AI is being developed and used

620
00:20:58,160 --> 00:21:00,400
responsibly, ethically.

621
00:21:00,400 --> 00:21:02,920
That's something that's come up a lot in our conversation.

622
00:21:02,920 --> 00:21:04,600
It's such an important point.

623
00:21:04,600 --> 00:21:08,200
As powerful as AI is, it's still just a tool.

624
00:21:08,200 --> 00:21:10,280
And like any tool, it can be misused.

625
00:21:10,280 --> 00:21:10,960
Right.

626
00:21:10,960 --> 00:21:12,880
One concern is that AI could actually

627
00:21:12,880 --> 00:21:15,240
worsen existing health disparities.

628
00:21:15,240 --> 00:21:16,400
Oh, how so?

629
00:21:16,400 --> 00:21:19,080
Well, if access to AI-powered health care

630
00:21:19,080 --> 00:21:21,680
is limited to certain groups, it could actually

631
00:21:21,680 --> 00:21:25,120
widen that gap between those who have access to the best care

632
00:21:25,120 --> 00:21:26,240
and those who don't.

633
00:21:26,240 --> 00:21:29,960
So it's really crucial that the benefits of AI and medicine

634
00:21:29,960 --> 00:21:31,320
are accessible to everyone.

635
00:21:31,320 --> 00:21:31,840
Absolutely.

636
00:21:31,840 --> 00:21:35,000
No matter their background, socioeconomic status,

637
00:21:35,000 --> 00:21:35,840
all of that.

638
00:21:35,840 --> 00:21:36,280
Right.

639
00:21:36,280 --> 00:21:39,920
And we also have to be mindful of potential biases

640
00:21:39,920 --> 00:21:43,400
in the data that's used to train these AI systems.

641
00:21:43,400 --> 00:21:45,960
We have to actively work to mitigate those biases.

642
00:21:45,960 --> 00:21:47,880
So if we're not careful, AI could

643
00:21:47,880 --> 00:21:50,160
end up perpetuating and even amplifying

644
00:21:50,160 --> 00:21:52,160
existing inequalities in health care.

645
00:21:52,160 --> 00:21:55,360
It all comes back to that idea of responsible development.

646
00:21:55,360 --> 00:21:58,640
Deployment of AI, making sure it serves humanity as a whole.

647
00:21:58,640 --> 00:21:59,480
Absolutely.

648
00:21:59,480 --> 00:22:04,040
AI has incredible potential to improve health care for everyone.

649
00:22:04,040 --> 00:22:06,640
But it's up to us to make sure that happens.

650
00:22:06,640 --> 00:22:09,080
Well, this deep dive has been quite the journey.

651
00:22:09,080 --> 00:22:11,520
We've explored the possibilities, the challenges,

652
00:22:11,520 --> 00:22:12,920
of AI and medicine.

653
00:22:12,920 --> 00:22:14,680
We've talked about the potential of AI

654
00:22:14,680 --> 00:22:16,080
to discover new treatments.

655
00:22:16,080 --> 00:22:18,080
We've talked about the ethical considerations,

656
00:22:18,080 --> 00:22:19,320
equitable access.

657
00:22:19,320 --> 00:22:22,600
We've really seen how AI is already changing health care

658
00:22:22,600 --> 00:22:25,280
and how it will continue to shape the future of medicine.

659
00:22:25,280 --> 00:22:27,120
Yeah, it's been a pleasure diving deep with you.

660
00:22:27,120 --> 00:22:28,720
Hopefully, this conversation has given you

661
00:22:28,720 --> 00:22:31,920
a better understanding of this complex and rapidly evolving

662
00:22:31,920 --> 00:22:33,680
world of AI and medicine.

663
00:22:33,680 --> 00:22:37,080
We hope you found this deep dive informative and engaging.

664
00:22:37,080 --> 00:22:39,120
We encourage you to keep exploring this topic,

665
00:22:39,120 --> 00:22:42,280
keep asking questions, and be an active participant

666
00:22:42,280 --> 00:22:44,480
in shaping the future of AI in health care.

667
00:22:44,480 --> 00:22:46,840
And remember, just like with any new technology,

668
00:22:46,840 --> 00:22:48,640
it's so important to stay informed

669
00:22:48,640 --> 00:22:51,240
and to engage in those thoughtful discussions

670
00:22:51,240 --> 00:22:53,600
about the potential benefits and risks.

671
00:22:53,600 --> 00:22:59,040
Thank you for joining us on the deep dive.

