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You know that you've been invited into that room for a reason, so just show up and be

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your authentic self.

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You're only going to do great science if you're really happy and if it fits in your life.

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It's also good to learn from the other people that you're working with.

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In the long run it's very satisfying, but it is an uphill battle and the only thing

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that sort of keeps you going is the mentors and allies and friends and collaborators that

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you meet along the way.

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What's your advice to a young graduate student charting a path for themselves?

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Be honest to yourself and know whether you really love what you're doing.

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Nothing good comes out of doing something for an outcome, for the PhD, for the MD, for

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this or that.

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If you love the doing of it, the process, it will never feel hard, even if that reward

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at the end gets to be a moving target, which usually it is.

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If you love the doing of it, if you walk into your lab or to your office and you sit down

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thinking something good is going to happen today or I have to get through this so that

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I can do something else that I'm really looking forward to.

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If you are honest to yourself and you don't force yourself to do something because you

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or somebody else has an expectation of you to behave or perform or do something else,

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you're going to be happy and it will come with a lot of good things.

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I got advice from an old mentor long ago who said if you're really interested in something

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like neuroscience, you should do something outside of neuroscience to see if you like

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it, right?

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So I did that.

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In orthopedics, it was unusual, I was like, oh, you know, I would be interested in the

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bone, you know, I'll do orthopedics.

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And it actually turned out to work out really well.

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When maybe you and I were coming up through the system, you became an expert in a very

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specific domain and that today we really try, you really have to start to work across disciplines.

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Yeah, it's harder for sure.

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And in neuroscience now in particular, because what you could possibly do with the range

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of tools that has emerged, the expectation for a high profile paper is that it's going

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to have a little bit of everything.

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And how could you do all that?

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So I think it becomes more important to work as a team and to have different people in

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the group that you see more co-first author or even three co-all gave the same amount

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of effort to the paper going on.

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But it's also good to learn from the other people that you're working with.

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The thing I try to do is just always like, know your stuff, you know, like bring some

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scholarship along, but just look at it with really open eyes, you know, curiosity, look

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at it for what's out there, you know, is this question everything.

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So I think, you know, I don't, it doesn't always work, but it kind of helps you getting,

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you know, stuck in like, you know, fashion corners of the field.

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Yeah, absolutely.

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So and then projecting out, like if you were giving some advice to the younger, obviously

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you do this all the time with your graduate students and trainees and that, you know,

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what do you say to them about that?

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Like getting on stock or framing out the questions in a way that will make them meaningful and

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important?

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Yeah, I sometimes feel for people in my lab because, you know, I really push them hard

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to make their own decisions and really to think like, is this really interesting to

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you?

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Do you care about this?

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Do you, you know, what do you think is going to, you know, how is this going to change

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the way you think about things?

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Is this going to change our understanding?

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I really try to operate at that very basic low level where I think things are really

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important.

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So I really try and I think, you know, there are many ways to be a successful mentor, but

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sort of my approach is really to try to help each individual find meaning and joy and their

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own, you know, pathway of the balance of productivity for themselves.

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So I try not, you know, I'm not one of those things like everyone has to do this every

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month and here we do, you know, it's all very more organic, kind of intense and organic.

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Working on personhood as well as just like, you know, this is a great project.

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And not just the person as a scientist, but the whole person, you know, like, I mean,

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I think you're only going to do great science if you're really happy and if it fits in your

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life.

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You've had a, you know, an extraordinary career.

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I mean, you really, really have and, you know, looking back on the things that happened and

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the people that you met, has it given you a sense for the path to success?

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And, you know, if you were to take that and turn it into advice for a youngster today,

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you have some pearls of wisdom.

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We always ask this question.

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Yes.

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Well, the world is changing dramatically, so I feel like I'm a bit dated already.

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Serendipity has been a big part of this.

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I started my lab out of graduate school from UCSF, went back to Japan.

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It was not something that I had imagined doing, but they were launching a new institute, the

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Riken Brain Science Institute.

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And the goal was to create something more Western, not the traditional hierarchical

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system of Japanese university.

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And I thought, well, who am I?

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I'm just starting out, you know, and I had a lot of interesting ideas, I thought, for

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the research, but was just untested.

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But I felt that I could bring the kind of Western infrastructure or ecosystem to a new

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institution.

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And in that way, felt like I could contribute right away in addition to eventually science.

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That was a very, very lucky break.

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I was, of course, anxious about doing that, but excited at the same time.

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It was an institution that had no tenure.

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It was on a five-year review cycle.

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And the challenge was there.

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The moving far from the familiar.

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But chances come around very rarely.

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And so I think my advice would be if a young person had an opportunity, they shouldn't

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be afraid.

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Yeah.

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Seize the day.

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Seize the day.

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Right.

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For youngsters up and coming, you know, you've traveled a certain path, you know, from an

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immigrant family, other humanities, and so on.

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When you turn around and you talk to your graduate students or even if you're out in

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the school system, what do you say to youngsters?

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What do you say about, you know, do you have some nuggets tips for life?

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For life?

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Oh, wow.

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Or the academy.

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It's interesting because I was not by any means a traditional success story.

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I think it took a long time for me to get off the ground.

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I mean, in terms of, you know, I was a postdoc for something like seven years, which may

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be more typical nowadays, just a larger commentary on academia in general.

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But you know, I didn't think that I would succeed in this career path.

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There was no indication I would for many, many years.

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I struggled.

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I didn't get my first faculty position until, you know, about 10 years ago.

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It's a lot of investment that you put in, not sort of knowing what will come out the

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other end.

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But, you know, and people will give you all kinds of advice, but it's kind of the survivorship

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bias.

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And that's for me, that doesn't necessarily mean it'll work for anybody else.

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But one thing that I found that I couldn't move away from was this kind of like, I have

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a unique perspective and I'm just going to keep doing the thing that I think needs to

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be done, whether it's looking at spontaneous brain activity when nobody else cared about

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that or, you know, whether it's looking at certain populations using certain approaches.

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I have a unique perspective and I'm going to be here and I'm going to bring that perspective

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to academia, whether they want it or not.

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It turns out eventually they do want it because, you know, sometimes if you're not from the

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majority group, you don't see anyone else that looks like you.

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You think, well, I'm the odd one out.

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I must be wrong.

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But the truth is, you know, that as we've talked about, you know, the diversity is what

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like drives the innovation in science.

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And so when you, you know, you stick it out, you stick to your, you know, try to bring

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people along, I guess, to your perspectives, in the long run, it's very satisfying, but

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it is a uphill battle.

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And the only thing that sort of keeps you going is the mentors and allies and friends

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and collaborators that you meet along the way who support you in that path.

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So there's the both sort of don't lose your hope, even though it sometimes looks bleak,

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but also like rely on those friends and connections and collaborations because that's what makes

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it all possible and worthwhile.

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A lot of our PhD graduates now, choosing not the academic route, choosing to walk away

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from the research enterprise.

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And of course, there's a big sucking sound as the big data firms, the Googles, the Facebooks,

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take the PhD students that would formerly have gone down that route into their more

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corporate world.

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Are you worried about that?

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And what would you say to a youngster looking at that fork in the road and saying, you know,

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I could go over into this corporate world and make a lot of money, let's face it, or

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should I stay in the academic track?

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Is there something that we should be saying to somebody to say, look, you know, stay the

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course, it's worthwhile.

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Academic research, you know, is fantastic.

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Who can have a better job than what we do, right?

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I mean, we wake up every morning and our goal is to just to come and think about, you know,

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what are the next questions we want to.

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So there's no other job that offers you this.

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So that's one, so I think personally what I feel is that what I tell students is that

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if you have the, if you feel that this is something critical for you and you have this

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drive inside yourself, you don't have, you know, to come and then, oh, what do I do today?

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I don't know where I'm going.

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So if you come, you know, every day and you get to the lab and you get, and you have this,

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all this thing driving you, that means that you have something inside you that is, you

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know, that is done for science, right?

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That's one thing where you should, because you need to have that.

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If you don't have that, probably you're not at the right place because you need that because

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it's, we know, we know what the cons are, right?

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It's competitive.

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There is a lot of people, there is a lot of very, a lot of ton of people who would want

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to go after the same, you know, funding that you will be doing, but there is place for

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you if you have that.

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And then of course, after that, you know, you need to take this and take advantage of

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that.

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Take your career, you need to take your career in your hands and move in forward.

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You know, you need to take the lead on your career and go with it positively and find

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with it, surround yourself with a good team of people, taking advantage of the resources

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that your graduate program offers you, taking, making a network, you know, talking with people.

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You need to develop network.

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So you need a lot of things that you need to, yourself, to take care of.

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But if you do that, people will be pleased, you know, and excited to give you and train

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you and help you advancing that.

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But you need to take the lead on your own career and you need to have this motivation.

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If you have that, there's no reason why you should not, you know, you should not succeed.

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There is place for you in research.

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I mean, that would be my thing.

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Have you picked up a specific mentoring style yourself?

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Is there something that you bring or that you'd say this is a key component?

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I think, you know, thus far in my experience, you know, so I've been at Yale for 14 years

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or so.

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Every student is different, right?

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You know, and I don't, I think if I have a mentoring style, it might be mostly centered

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around being very patient, you know, very, trying to be very, very tolerant of the differences

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between other people, how their styles might, might interact with others in the lab group

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or with me.

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You know, I, I try not to impose too many of my own, the expectations I had for myself,

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I try not to impose them on my students because their style and their, their learning style

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might be different from mine or their goals in life might be different from mine.

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So yeah, I love that answer.

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And I often get asked the same thing.

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And I say like, you know, people in the lab are just human beings, like the human beings

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in your world, in your life, and they come in all shapes and sizes and you have to figure

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out a way to fit around that.

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Yeah, everybody has a real life too.

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You know, it isn't, it isn't science 100% of the time, although sometimes it is, like,

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I have trouble turning off the science in my head.

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But you know, people come to the lab and they have had a bad day or they have, you know,

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a family crisis or, you know, or something else is more important that day than, you

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know, this one experiment.

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And you know, that's, that's a real thing.

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It's not just science, it's also everybody's real life too.

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You've had an amazing life really, you know, you've reached the absolute pinnacle of the

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Academy from a small town in Virginia.

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When you talk to your graduate students or youngsters in the schools, and they say like,

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you know, what do I, how do I do it?

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How do I, how do I do what Brian Boyd did?

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Do you have, do you have some pearls of wisdom for them?

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Yeah, yeah, I guess two pieces of advice.

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For me, and I think for other people in the field that I've interacted with as well, I

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think, you know, mentors are really important.

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You know, find your supportive mentoring network.

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And sometimes you need mentors for different reasons.

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Sometimes it's not just about the science.

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Sometimes it's just about navigating academia.

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When I was in my doctoral program, one of my mentors was a Latina woman.

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And I talked to her about what it's like being a minority in the Academy.

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And those are the conversations we had.

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But they were really important for my career.

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So find your mentoring network, that support.

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The other I would say to people, and I often hear this from students who are from marginalized

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backgrounds, this whole concept of imposter syndrome.

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And I feel like an imposter.

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And I would say that, again, most people I've talked to in the Academy, at some point in

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their career, felt like an imposter.

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So know that you've been invited into that room for a reason.

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So just show up and be your authentic self.

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So those are my two pieces of advice.

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As somebody who's really had a fantastic career, what's that one pearl of wisdom?

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What do you say to them?

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What's going to get them through?

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Yeah.

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So single pearls are always a problem for me.

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We have one minute.

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You can do five.

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And I think one might be to identify not a problem right this moment that you want to

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attack that's important, but what would give your entire career in its inevitable arc meaning

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and importance so that if you got there, you would have felt fulfilled.

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And to some of us, that has some sort of highfalutin kinds of words like changing the world or

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discovering things that will help large classes.

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To some people, it might be equally important, but to answer this question that's always

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been unknown, and if you have that, I think the complexities of life become just steps

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toward that fascinating goal.

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And that might be toward human health, toward the betterment of the world, or maybe just

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discovering the subatomic forces that explain black holes.

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Just that.

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Thank you.

