WEBVTT

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Hey everybody, welcome back. It's your host,

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Neogentrics here with Food for Thought, Thoughts

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that Fit for You, A Dark Cancer Production Season

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3. And we're back with another episode. Today

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we're going to be talking about these synthetic

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opioids. I have four of them listed here. Last

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time we talked about one of the most common but

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most dangerous organic opioids. But today we're

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going to talk about two, three, maybe four of

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them. of the synthetic ones, but we're going

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to also cover the most dangerous one of them

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all, fentanyl. And we're going to go ahead and

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get started with that right quick in a few seconds.

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Now, just to give a quick update, there's been

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a lot of stuff going on in my life that have

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been delaying me from doing some of the stuff

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that I would love to do. But like I said, I plan

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to be making more episodes more often for each

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and every one of you. So again, thank you for

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your time and thank you for listening in. And

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I hope you enjoy. So let's get started. All right,

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all right, all right, everybody. Let's get started.

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First up on the docket is the synthetic opioid.

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Now, if you remember, real quick before we go

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any further, that we have been talking about

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opioids for the last couple of days. And we talked

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about the difference between organic and synthetic.

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And the fact that the synthetic ones are man

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-made. And they're just as dangerous, if not

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more dangerous, depending on which one it is.

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Regardless of that fact, though. for human consumption

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in large quantities. So we're going to pick up

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where we left off with the synthetic opioids,

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starting with hydrocodone. It's similar to oxycodone,

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except this one is a synthetic opioid drug, okay?

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It's used to relieve moderate to severe pain,

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and it's often combined with other medications

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such as acetaminophen and ibuprofen. It's also

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available in various formulations, including

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tablets, capsules, and syrups. So it just depends

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on how you receive it. Typically, you would get

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this from a doctor, but you can buy it over the

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counter in small quantities. It works by binding

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specific receptors in your brain and the spinal

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cord, which then reduces the sensations of pain

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that you feel. And like oxycodone, hydrocodone

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is also a schedule two controlled substance,

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which means it also has a high potential for

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abuse and dependency depending on how it's used

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or if it's misused. And if misused, and continuously

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so, it can lead to addiction, overdose, death.

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Same similar stuff as the other one. Okay. It's

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crucial for patients to understand that the risks

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associated with taking hydrocodone, and that,

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like I mentioned before, with the other one,

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they must follow the doctor's instructions very

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carefully, to a T if they can, and it should

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only be taken as prescribed. Never shared recreationally,

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never shared regardless to anybody, especially

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someone who you don't even know if the person

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will have side effects to it that you don't have

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just because it didn't affect you the same way.

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And on the topic of side effects, it's important

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to be aware of potential side effects of hydrocodone.

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Much similar to oxycodone, it includes nausea,

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vomiting, constipation, dry mouth, and dizziness.

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Like I mentioned before, if you experience any

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serious side effects, be sure to contact your

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doctor right away. The reason I bring this up

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is because hydrocodone is a very, very, very,

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very powerful opioid pain medication. And it's

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commonly prescribed for those type of pain, like

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moderate to severe pain. Like if you've been

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in a wreck, an accident, been hit by a truck.

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Yes, that's a scenario apparently nowadays. anything

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of the sort. But like anything else, there have

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been a high number of unfortunate incidents reported

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in the recent years that involve hydrocodone.

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And like I said, one of the major issues with

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it is the addiction and overdosing of it. So

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with that understanding, okay. It's a highly

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addictive substance, right? And long -term use

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can lead to dependency and withdrawal symptoms.

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And when I say dependency, I mean it can lead

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to an addictive type, characteristic type behavior

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with a need or drug -seeking behavior that the

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person is unable to control. Meaning they are

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going to try to get this drug. no matter what

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it takes, regardless of what they have to do.

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Now, with that being said, the prevalence...

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Actually, let me go ahead and say it like this.

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There's another issue. Unrelated to everything

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that I've just been spouting for the last four

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minutes, is the prevalence of counterfeit or

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illegally obtained hydrocodone. The reason I

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say this, much like everything else on this list,

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It can be mixed with other drugs, including fentanyl,

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which increases the risks of overdosing and people

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becoming addicted to it. And the people who purchase

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these drugs, especially on the street, will never

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know whether or not this drug is pure or not,

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okay? Which has led to one of the highest concentrations

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of the opioid crisis here in America. But it's

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spreading. to high numbers of people with a large

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number of people ODing on it to the point where

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they die every single year. So if you know someone

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who's taking it and they don't have a reason

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to be taking it, you need to find them help.

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Don't try to stop them yourself because that

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puts you and them at risk, but you should try

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to seek help for them and try to convince them

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to go to counseling of some sort or go to therapy

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to help them, you know, get over it, okay? So

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just to recap, it's a very powerful drug. It's

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highly addictive. It's usually used for managing

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moderate to severe pains. There are high OD risks

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with it, and there are high rates of addiction,

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overdose, and death, along with counterfeit or

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illegally obtained hydrocodone that can have

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severe or serious side effects or high -level

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dependencies on it because it's mixed with something

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else. Okay, so we got hydrocodone out of the

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way. Like I said, most of the information about

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it is pretty similar to oxycodone. I don't need

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a full episode on that. Just about five minutes

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and that was fine. Now let's move on to something

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that's a little more potent, if not more dangerous

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than oxycodone or hydrocodone. And that would

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be the synthetic opioid fentanyl. Okay, fentanyl.

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like, uh, hydrocodone is also a synthetic opioid

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that is, and I might, I'm not exaggerating this

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when I say this, it is 50 to a hundred times

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more potent than morphine. Okay. For those of

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you who know what morphine is, if you don't,

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uh, check out the episode, I'm probably do later

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on what morphine and other drugs similar to that

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is, but for now, uh, it is. basically prescribed

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for extreme to severe pain such that it's caused

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by cancer or surgery so it's not likely to be

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something that doctors are going to give out

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like candy i promise you there has to be a severe

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need or urgency for them to want to give this

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out to anybody now like i said it's it's prescribed

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for severe or extreme pain and such as that it's

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caused by cancer surgery and is often used in

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the form of a patch or a lozenge for obvious

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reasons. However, it can also be illegally produced

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and sold, often mixed with other drugs such as

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heroin or cocaine, which we'll talk about on

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another episode. This illegal use has led to

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significant increases in overdose deaths over

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the last couple of years, and like most of the

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other opioids, fentanyl works by binding to the

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body's opioid receptors. which are found in the

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brain and spinal cord. And this binding reduces

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the perception of pain and can also cause feelings

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of euphoria, almost like LSD. However, because

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of its potency, even small amounts of fentanyl

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can cause respiratory depression, which can lead

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to an instant overdose and death, which is why

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when it's prescribed, it's prescribed in the

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smallest of doses. And I'm talking about smaller

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than milligrams, because depending on how much

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you need and depending on how severe the pain

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is will determine how much the doctor gives you,

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because depending on your body will determine

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how your body process it and whether or not it

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can get to the point where your body either needs

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it to survive or you start becoming dependent

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on it, which they don't want. So, again, this

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is something that they rarely will ever give

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you. Okay. Fentanyl overdose symptoms typically

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include slow or shallow breathing, confusion,

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drowsiness, small pupils. If someone is suspected

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of having fentanyl overdoses, they should be

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given naloxone. It's a medication that can reverse

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the effects of opioids and seek medical attention

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immediately. With that being said, by the way,

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because... Even though this does reverse some

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of the effects, it will not make them non -codependent.

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This takes time. The use and abuse of fentanyl

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has become a public health crisis in many countries.

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And the Center for Disease Control, or the CDC,

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estimates that more than 31 ,000... overdose

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deaths in the united states in 2008 alone uh

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involved synthetic opioids which included fentanyl

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which has for whatever reason resurfaced at the

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end of 2022 the beginning of this year and i

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have no idea what that's about but that just

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means that you need to be very very careful when

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going outside and going places especially when

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picking up random stuff on the sides of the road

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that looks like they should be harmless but they

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probably aren't The government and public health

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organizations are working to raise awareness

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about the dangers of fentanyl and to provide

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resources for those who are struggling with that

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addiction. So there are resources out there for

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people who need it. You just have to go and look

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for it. Long story short, or rather in conclusion

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on what I'm trying to say about fentanyl. Long

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story short, it's a synthetic opioid that is

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highly potent, can be very dangerous when misused.

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It's important to only use as prescribed and

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to be aware of the risks of overdosing by taking

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even a little bit too much. If you know someone

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who is struggling with addiction to fentanyl

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or other opioids, help is available. And you

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can contact the Substance Abuse and Mental Health

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Services Administration or SAMHSA national helplines

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for those who need help or for yourself if you

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think you need help. Hold on here. Actually,

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I do believe I have it. Yeah. So the phone number

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is 1 -800 -662 -HELP or 4357. For more information,

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this number may or may not vary depending on

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the state you're in. But for the general phone

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line, I do believe this is the number. Just something

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to keep in mind. Alright everybody, I'm not quite

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done yet. There's still a few more that I, still

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another one I need to talk about. I did mention

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fentanyl, and yes, it is extremely dangerous,

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but there's something similar to fentanyl that's

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just as dangerous, probably more dangerous than

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fentanyl. Just not as common, but it is there.

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and that would be the synthetic opioid carfentanil.

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Just add the word car in front of the word fentanyl.

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I promise you, you probably have seen this before,

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but didn't know how to pronounce it, or you may

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have never heard of it, but you didn't realize

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it. Anyway, carfentanil is a synthetic opioid,

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much like the other two. that is estimated to

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be about 100 times more potent than fentanyl

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and 10 ,000 times more potent than morphine,

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meaning it's extremely effective. And this specific

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drug, and dare I even say this for most people

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who shouldn't even know this, but it is primarily

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used in tranquilizers for large animals such

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as elephants, but it has been found in illegal

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drug markets in recent years. And you're like,

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well, Nia, why are you bringing up car fencing

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if it's mainly used in tranquilizers for animals?

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You'd be surprised. In other countries, drugs

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aren't regulated like they are here. So a tranquilizer

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dart that they use on humans may be the same

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tranquilizer dart they use on animals, which

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means that there's a high risk that you can still

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end up with this in your system without realizing

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it. There's also a chance that you could come

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across it mixed with something else entirely,

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like carfentanil could be mixed with fentanyl,

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morphine, and a bunch of other drugs together

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and you wouldn't even know. That being said,

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carfentanil, like the others, is a scheduled

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-to -control substance, and in the United States,

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which it means that it has a high potency for

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abuse and dependence, as like everything else.

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It can be prescribed by a healthcare professional

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for the management of severe pain, but it should

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only be used under, again, close medical supervision.

00:15:19.389 --> 00:15:23.710
Okay, well, that's fine and all, but again, carfentanil

00:15:23.710 --> 00:15:26.490
is mainly used for tranquilizers, and we don't

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really use tranquilizers on humans, or at least

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we would like to believe that, because, you know,

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it's inhumane. Well, you may believe that, but

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a lot of people out there don't, and there are

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people out there who still do this. The high

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potency of carfentanil makes it particularly

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dangerous for misuse and accidental ingestion

00:15:45.690 --> 00:15:48.950
as well. Even a very small amount of this drug

00:15:48.950 --> 00:15:52.009
can cause an overdose, which can lead to respiratory

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failure, a coma, or in some people's cases, death.

00:15:56.190 --> 00:15:58.190
That being said, and this is something I didn't

00:15:58.190 --> 00:16:00.509
mention before with fentanyl, but carfentanil

00:16:00.509 --> 00:16:02.450
and fentanyl can also be absorbed through the

00:16:02.450 --> 00:16:07.419
skin as a powder, so keep that in mind. Another

00:16:07.419 --> 00:16:09.860
issue is its prevalence of counterfeit or illegally

00:16:09.860 --> 00:16:13.179
obtained carfentanil. These drugs can often be

00:16:13.179 --> 00:16:14.919
mixed with other substances, as I've mentioned

00:16:14.919 --> 00:16:18.360
before, such as heroin or cocaine, and that also

00:16:18.360 --> 00:16:21.720
increases its risk of overdosing. And since you

00:16:21.720 --> 00:16:24.019
can't check the purity of these drugs when you

00:16:24.019 --> 00:16:26.779
get them on the black market or such, it's very,

00:16:26.820 --> 00:16:29.000
very dangerous to even accept it from anyone,

00:16:29.200 --> 00:16:33.519
especially when you don't know what it is. You

00:16:33.519 --> 00:16:35.860
know, like I mentioned earlier, the opioid crisis

00:16:35.860 --> 00:16:38.639
here in the United States has been mainly driven

00:16:38.639 --> 00:16:41.740
in part by the proliferation of synthetic opioids,

00:16:42.000 --> 00:16:45.480
including carfentanil, fentanyl, hydrocodone,

00:16:45.639 --> 00:16:48.440
and tramadol, just to name a few, okay? This

00:16:48.440 --> 00:16:51.799
isn't all of them. This is just a few that I'm

00:16:51.799 --> 00:16:54.139
talking about now just to bring some attention

00:16:54.139 --> 00:16:58.240
to it, okay? The opioid epidemic has resulted

00:16:58.240 --> 00:17:00.799
in high number of overdose deaths each year,

00:17:01.080 --> 00:17:03.039
carfentanil being one of the most potent and

00:17:03.039 --> 00:17:04.920
dangerous synthetic opioids that's available

00:17:04.920 --> 00:17:08.299
on the market. And much like everything else,

00:17:08.319 --> 00:17:11.160
like I said, should not be taken recreationally

00:17:11.160 --> 00:17:13.380
and must be taken under medical supervision.

00:17:13.539 --> 00:17:19.220
So to recap just how bad this is, the misuse

00:17:19.220 --> 00:17:22.299
of carfentanil. can lead to addiction, overdose,

00:17:22.539 --> 00:17:25.559
and death. It is estimated to be, as a synthetic

00:17:25.559 --> 00:17:28.680
opioid, to be 100 times more potent than fentanyl

00:17:28.680 --> 00:17:32.079
and 10 ,000 times more potent than morphine.

00:17:32.339 --> 00:17:35.500
And while it's mainly used in tranquilizers for

00:17:35.500 --> 00:17:38.900
animals, it can still be bought illegally, which

00:17:38.900 --> 00:17:41.680
makes it just as dangerous and just as high a

00:17:41.680 --> 00:17:44.779
chance of misuse or accidental ingestion without

00:17:44.779 --> 00:17:47.640
paying attention or by picking up something random

00:17:47.640 --> 00:17:50.000
on the side of the road. We both... all know

00:17:50.000 --> 00:17:52.380
that homeless people exist on the side of the

00:17:52.380 --> 00:17:54.240
road. Not every homeless person is innocent.

00:17:54.400 --> 00:17:56.740
This is true. But not every homeless person is

00:17:56.740 --> 00:17:59.859
a druggie or a drug head. Okay? That being said...

00:18:00.329 --> 00:18:02.410
We don't know what all is being passed around

00:18:02.410 --> 00:18:04.849
between them or what else is there, so if one

00:18:04.849 --> 00:18:06.710
of them drops something that looks like it's

00:18:06.710 --> 00:18:09.049
a pouch or something, your best action would

00:18:09.049 --> 00:18:12.049
be to probably just leave it alone and walk away.

00:18:12.230 --> 00:18:14.269
Though I know probably out there, there are a

00:18:14.269 --> 00:18:16.289
lot of people out there who will not do this.

00:18:16.589 --> 00:18:19.529
And for that, all I can say is to each their

00:18:19.529 --> 00:18:21.990
own. If you want to take that risk, by all means,

00:18:22.049 --> 00:18:26.690
go for it. But just be advised, be safe, and

00:18:26.690 --> 00:18:30.400
take precautions. Got one more to go. Let's do

00:18:30.400 --> 00:18:49.140
this. Hey, everybody. Welcome back. I was going

00:18:49.140 --> 00:18:51.920
to say that carfentanil was the last of the synthetic

00:18:51.920 --> 00:18:54.220
opioids that I was going to cover today, but

00:18:54.220 --> 00:18:56.579
I feel like I should cover something that's a

00:18:56.579 --> 00:18:58.779
little less potent than the three I mentioned.

00:18:59.519 --> 00:19:02.359
And I said it earlier in one of the previous

00:19:02.359 --> 00:19:04.799
parts of this episode, but I'll just go ahead

00:19:04.799 --> 00:19:07.220
and state it again for clarity. And that's the

00:19:07.220 --> 00:19:11.099
synthetic opioid Tramadol. Spelled T -R -A -M

00:19:11.099 --> 00:19:15.160
-A -D -O -L. It is an opioid medication that's

00:19:15.160 --> 00:19:17.539
used to manage moderate to severe pain, just

00:19:17.539 --> 00:19:20.180
like all of them are, because that's essentially

00:19:20.180 --> 00:19:23.349
what opioids do. but it works by binding to specific

00:19:23.349 --> 00:19:25.769
receptors in the brain that reduce the perception

00:19:25.769 --> 00:19:28.170
of pain. It's different from the other ones,

00:19:28.230 --> 00:19:31.750
as it only affects the levels of certain neurotransmitters

00:19:31.750 --> 00:19:35.650
in your brain, which can increase its effects.

00:19:36.089 --> 00:19:40.390
However, Tramadol is available in both immediate

00:19:40.390 --> 00:19:42.849
release and extended release formulations, and

00:19:42.849 --> 00:19:46.529
it can be used or taken orally or by injection.

00:19:47.480 --> 00:19:49.680
It's typically prescribed for short -term pain

00:19:49.680 --> 00:19:53.359
management, usually after surgeries or an injury.

00:19:53.720 --> 00:19:56.359
It's usually the better alternative than the

00:19:56.359 --> 00:20:00.259
others. However, it can also be prescribed for

00:20:00.259 --> 00:20:03.420
chronic pain, such as in the case of cancer.

00:20:04.839 --> 00:20:07.960
While Tramadol, unlike the others, is considered

00:20:07.960 --> 00:20:10.339
to be less potent than the other opioids, it

00:20:10.339 --> 00:20:13.000
still has the potential for abuse and dependence

00:20:13.000 --> 00:20:16.430
and overdosing. The difference is it's not as

00:20:16.430 --> 00:20:19.210
bad, but it's still there. Long -term use of

00:20:19.210 --> 00:20:21.410
Tramadol can lead to physical dependence, which

00:20:21.410 --> 00:20:24.329
means the person adapts to the drug and requires

00:20:24.329 --> 00:20:26.910
more of it to achieve the safe effect that it

00:20:26.910 --> 00:20:29.289
does. And of course, misuse of Tramadol leads

00:20:29.289 --> 00:20:31.509
to addiction, characterized by the compulsive

00:20:31.509 --> 00:20:34.410
drug -seeking behavior I mentioned earlier, and

00:20:34.410 --> 00:20:36.809
the inability to control the use, let alone their

00:20:36.809 --> 00:20:39.680
desire for it. Obviously, mixing Tramadol with

00:20:39.680 --> 00:20:41.779
other substances such as alcohol can lead to

00:20:41.779 --> 00:20:44.059
risks of overdosing or serious side effects.

00:20:44.200 --> 00:20:46.880
So definitely don't do that. And it can also

00:20:46.880 --> 00:20:49.859
interact with other medications such as antidepressants.

00:20:50.119 --> 00:20:52.859
So it's important to inform your healthcare provider

00:20:52.859 --> 00:20:54.960
of all the medications you are taking before

00:20:54.960 --> 00:20:58.160
you start taking this. Because unlike the other

00:20:58.160 --> 00:21:01.039
ones, this one will mix with what's there and

00:21:01.039 --> 00:21:02.680
will either increase its effects or slightly

00:21:02.680 --> 00:21:06.819
change its effects based off of it. Also... Since

00:21:06.819 --> 00:21:09.660
I've done brought this up, it's also important

00:21:09.660 --> 00:21:11.680
to note that trombone may also cause withdrawal

00:21:11.680 --> 00:21:14.200
symptoms if it's just suddenly stopped. This

00:21:14.200 --> 00:21:16.519
is one of those drugs that you have to slow your

00:21:16.519 --> 00:21:19.440
roll off of if you've been taking for a while.

00:21:20.000 --> 00:21:22.819
And it's important to follow the dosage schedule

00:21:22.819 --> 00:21:24.740
that is directed by healthcare professionals,

00:21:24.980 --> 00:21:27.319
especially the one who assigned it to you, and

00:21:27.319 --> 00:21:30.480
to talk to your doctor before you just stop taking

00:21:30.480 --> 00:21:32.579
it. This is not something you can just stop.

00:21:33.829 --> 00:21:37.170
Okay? While it's not as dangerous as the other

00:21:37.170 --> 00:21:41.410
ones, as far as potency is concerned, it's still

00:21:41.410 --> 00:21:44.529
just as effective, if not as dangerous, in the

00:21:44.529 --> 00:21:46.630
sense that it's not something that you can walk

00:21:46.630 --> 00:21:49.430
away from and just be like, okay, I'm done taking

00:21:49.430 --> 00:21:52.509
this today, and you're done. That's not how this

00:21:52.509 --> 00:21:57.990
one works. In summary, Tramadol is a synthetic

00:21:57.990 --> 00:22:00.730
opioid medication that is used for monitoring

00:22:00.730 --> 00:22:03.980
severe pain. It's less potent than the other

00:22:03.980 --> 00:22:06.019
opioids, but still has the potential for abuse,

00:22:06.099 --> 00:22:09.420
dependency, and overdose. And it's very important

00:22:09.420 --> 00:22:12.539
to be aware of the risks and to take steps to

00:22:12.539 --> 00:22:14.220
protect yourself and your loved ones when you

00:22:14.220 --> 00:22:16.900
have to take it, if you have to take it at all.

00:22:17.900 --> 00:22:21.359
Okay? So with that, that's all I'm going to cover

00:22:21.359 --> 00:22:24.539
on synthetic opioids, or at least certain names

00:22:24.539 --> 00:22:27.920
or branded ones. for now we're going to take

00:22:27.920 --> 00:22:29.680
a break we're going to go back to talking about

00:22:29.680 --> 00:22:31.059
learning styles and then we're going to come

00:22:31.059 --> 00:22:33.920
back and talk about certain stimulants that are

00:22:33.920 --> 00:22:36.579
available as narcotics as well as depressants

00:22:36.579 --> 00:22:40.980
hallucinogens inhalants and of course at some

00:22:40.980 --> 00:22:43.519
point we have to get to cannabis but like i said

00:22:43.519 --> 00:22:45.640
there are many other things that i want to cover

00:22:45.640 --> 00:22:47.500
things that i said i was going to cover that

00:22:47.500 --> 00:22:51.180
i haven't covered um but That's the thing that

00:22:51.180 --> 00:22:54.000
we're going with now. Also, if you know anybody

00:22:54.000 --> 00:22:56.859
who has had to deal with this or had to deal

00:22:56.859 --> 00:22:59.319
with any of these opioids, feel free to leave

00:22:59.319 --> 00:23:01.019
a comment down below. I thank you for your time.

00:23:01.299 --> 00:23:06.140
This is your host, Neogentrix, signing out. And

00:23:06.140 --> 00:23:08.759
I hope you have a great rest of your day. Try

00:23:08.759 --> 00:23:11.200
to stay drug -free and be blessed.
