For today's episode, Nicole Rincon returns to
talk about various gastrointestinal related problems,
biomarkers, and treatments related to autism.
Nicole will take us through a few pre -pregnancy,
pregnancy, and for the autistic child to increase
our awareness and tools to consider for reducing
the rates of autism and for mitigating symptomatic
problems. with GI and autism. Nicole Rincon is
a board -certified physician assistant with over
17 years working in medicine. Currently, Nicole
works at the Razignol Medical Center, which includes
doctors Dan Razignol and Richard Fry. With over
17 years in medicine, working with various conditions,
and her drive as a mother, Nicole continues to
offer tremendous knowledge on the topic of autism
and other related conditions. Check out the show
notes for more information on Nicole. But for
now, an important message about Daylight Computer
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off Nicole welcome back. I'm so happy that you
joined again Thanks for having me. It's great
to see you again. Yeah, so fun talking to you
on and offline actually perfect Well, you can
reach out anytime. I'm really I've been trying
to be more active on my ex profile. So, you know,
I'm answering a lot of just patient emails, but
just, just, you know, general people inquiries.
So if you ever want to, Hey, Nicole, what about
this? Or what's the study? Or what do you think?
Just reach out. I'm there. I'm what's my handle
at Nicole Rincon PA, I believe. Yeah. I put that
in the show notes again. It's a wonderful follow.
You're a great follow. I have something that
from about a month ago that I want to ask you
about later on. that you mentioned on X and it
was like, wow. I was hoping that we could start
with a pre -pregnancy related to gastrointestinal
things that a mother could be on the lookout
for as she's going into, let's say like a planning
pregnancy. Maybe she has a child with autism
already or not. Maybe you can discriminate between
that, what that looks like. But are there standard
checks related to GI? that a mother could look
out for? Yeah, that's a great question. And I
think we touched on it at one of our last podcasts,
but definitely maternal abnormalities can contribute.
They found that there's a lot of maternal risk
factors for autism spectrum in their offspring.
And so I think I mentioned we do this at our
office sometimes. Like you said, even for pregnant
people that are high risk, maybe there's a family
history of autism, or there was a previous child
that had autism and they want to try and prevent
it. So there is a lot of things we can do and
should do prior to even conception. You mentioned
GI. I mean, we do, let me start with the blood
work first. So we typically do a blood work panel.
And I think we did mention that last time, thyroid
is very important. I know we mentioned that.
We always look at vitamin D levels, make sure
those are between 60 and 80. The standard is
like 30 for standard medicine saying that that's
the cutoff. That's low. I mean, it typically
is associated with higher disease outcomes. So
we're looking at, we want to get it. Last time
I checked mine was 83 and I was ecstatic. That's
about where I want it to be. So vitamin D3 is
important. Looking at anemias, making sure that
iron is appropriate. So the best way to assess
for iron deficiency anemia with iron stores is
ferritin. So you normally get a hemoglobin and
a hematocrit, but then you get the iron levels.
Make sure that usually we want those above 50
for most people. So again, the reference range
is really, you know, kind of not appropriate
if it's, you know, some people say, oh, it's,
I think it's 20 depending on the lab, but we
try to get it up to 50. We'll look at things
like MTHFR genes. So if there's methylation issues,
we see that a lot with miscarriages. I know we
talked about the folate receptor antibodies.
Definitely that is associated with higher. miscarriage
outcomes. So we want to make sure they're getting
good appropriate folate on board. So again, I
mentioned that last time, it's so important to
treat the MTHFR. You might need maybe one milligram
of methylfolates, but to treat the folate receptor
antibodies, there's been a big push on X. Everybody's
been talking about it. And it's true. It's a
really big breakthrough in research in the past
decade. You're going to want to take higher doses
of active but not methylated folate, like folinic
acid specifically. So we look at that and we
will supplement, you know, put mothers on leucovorin
and or methylfolate. We want to look at some
mitochondrial dysfunction. If the mother's energy
production is low for some reason metabolically,
then that can be associated with autism. So we'll
look at things like carnitine, which is associated
with metabolic mitochondrial dysfunction. Other
things, you know, we can look at CoQ10 levels.
That can be very important. The other things,
you know, obviously the general screenings are
going to do liver function, kidney function,
you know, diabetes, make sure blood sugar is
normal. Western medicine is pretty good about
looking at that. And inflammation is big too.
So we have the CRP. ESR, you know, these markers
are just they don't obviously indicate where
the inflammation is coming from. But if there
is an inflammatory condition in the mother, especially
like autoimmune disorder type inflammation, like
rheumatoid arthritis, that kind of thing, then
we should definitely be looking at that. And,
you know, ideally, depending on how high the
inflammation is and what the kind of what the
profile looks like, we may want to treat that
first. And that doesn't necessarily just mean,
OK, let's put them on Plaquenelle or whatever
they're going to normally treat autoimmune with,
but really trying to look at the root cause.
So a lot of what we do in the moms is really
like what we're going to do in the kids. And
we're just hopefully prepping the mom to avoid
the disease in the kid. Because oftentimes you'll
find these abnormalities. And you're saying,
oh, well, a lot of this was genetic, came from
the mom, there was toxins passed down, inflammation
passed down, mitochondrial deficits, that kind
of thing. So those are kind of generalized. markers
that we look at for blood. And a stool analysis,
yeah. I mean, if a mom's coming in and she's
like, yeah, I've had constipation my whole life,
I've had diarrhea or bloating after every meal,
different GI, then definitely the gold standard
that we do for just generalized stool analysis
is comprehensive stool analysis, like a CSA,
and that's what it's called. And they do... You
know it gives you a comprehensive what's growing
in your really in your lower intestine in the
colon So it'll give you bacteria fungus We'll
check for parasites. I do find parasites. It's
crazy. I mean you don't think in the Western
world like you You know you read it online, but
it really is a thing and it really does actually
even come up on the stool so checking for that
Inflammation in the gut so if you're suspecting
that there's inflammation for the blood look
at the gut first You know you can do to calprotectin
a zonulin level looking for a leaky gut And all
these things, like I said, usually come included
on the stool analysis. So that's a really big
one. And oftentimes, I think I might have mentioned
this last time, let's say that the mom has rheumatoid
arthritis, and we test her gut, and she's got
this huge amount of Proteus Mirabilis. And it's
like, well, that might be coming from the gut.
So Proteus Mirabilis overgrowth is associated
with rheumatoid arthritis. There's been several
studies. You can look at PubMed. you really understand
that the immune system is usually coming from
the gut. So we look there. And so it's really,
actually it's really cool. I mean, it's unfortunate,
but I mean, it's cool when you find these correlates,
like, oh, your symptoms correspond with this
test and holy cow, like now we can treat it.
So it's one of those awesome aha moments that
we do get. I mean, I don't always get it. We
hope for it, but I do sometimes get it. So it's
great that we can make an actionable plan. And
then the other test, a lot of providers talk
about it online, and I totally agree. There's
an organic acid test. Right now, it used to be
Great Plains Laboratory. Now it's Mosaic, I believe.
We're not affiliated with them in any way, but
it is kind of the gold standard for an organic
acid test. And that can show... Very well other
chronic infections, so it'll show metabolites
of yeast of other fungus like molds bacteria
Clostridia It'll give you some mitochondrial
inflammation oxidative stress vitamins. It's
really a comprehensive test The downsize is it's
just one snapshot of one urine test and I mean
that's kind of all tests in general and sometimes
things are missed but It can really show a good
amount of chronic infection sources, you know
between like like I said the fungus and bacteria
kind of genre it's not very good at viruses,
but But that can be it can be a big piece. So
those are kind of the two GI tests I would say
you're asking specifically by GI is the oat organic
acid test and the and The stool test so super
helpful And, you know, that really does give,
I mean, if the oat looks perfect, it's gorgeous,
then we're thinking, okay, this is pretty good,
but I've seen them in, you know, neurotypical
people and they're healthy, they're walking around
and their oats look pretty bad. Are you having
symptoms? Are you having problems sleeping? Are
you having joint pain? Oh yeah, my back does
hurt a lot. I just thought it was aging, you
know? And so there's a lot of symptoms that people
just chalk up to. just getting old or whatnot,
this is me, you know, and it's really an infection
that they didn't know about or dysbiosis, you
know, some kind of abnormal balance. Brian, I
can't hear you anymore. I'm not sure if that's.
How about now? There you are. Perfect. Now I
got you. Yeah, as you as you were talking, though,
I was like, stop talking to myself. So maybe
that was just it. Right. CSA, I put it together.
That's comprehensive stool analysis. That's what
that's just what it is. Yes. Yeah, I was doing
that a lot. Oh, sorry. Sorry. Because I'm ever
confusing because it's hard, you know, you have
the curse of knowledge. So I say these things
and think, oh, everybody knows this is standard
in my world. But of course, so please ask because,
you know. Yeah. These types of labs are like
so new to me. Yes. I'm famous on this. That's
why I want to talk to you about it. Yeah. Can
we go back to the MTHFR lab? What is that lab
work or what is that draw? That's a good question.
So it's a blood draw and now it's nice. You can
get it through Quest or LabCorp, just your standard
blood, you know, stations. And it's one test
and it looks for the genetics specifically associated
with methylated folate, you know, prior to the
methylation cycles. So we, there's two gene variants
that they look at C677 and then 1298 and They'll
give you basically what genes you have. If you
have all four of them as bad genes, like both
alleles on both genes, I know that's kind of
a lot of genetics, but basically you can have...
four out of four of them good, three out of four
of them good, two out of four, one out of four,
and then zero out of four. Usually anybody that
has more than two bad, it's not a viable pregnancy.
So like most, you won't really find anybody walking
around with three or more bad alleles in those
two genes. So, because it just won't support
life. And you know, the DNA won't get methylated
properly, people won't grow, the development
won't happen. So, but it's really important,
and I have so many patients. I had one of my
best friends, I mean, she was having a lot of,
she just had another baby, and she was on her,
after her fourth pregnancy, super fatigued, not
feeling well, and we were just talking, and I
thought, I asked her, have you tried methylfolate?
You know, methylfolate, she's like, what's that?
You know, so I gave her, I don't know what I
gave her, I think it was five milligrams a day,
because. She wanted to see results, and she said
it was game -changing. She said, this is life
-changing. I have my energy back. I can take
care of my kids. So some people, even if, like
I said, you're not on the spectrum, you need
that support. And it really does help. I take
it every day. I feel much better. I know when
I miss some of my methylated vitamins. I can
totally tell. I'm just dragging, my brain's not
as sharp. I'm walking around, I'm doing it, but
I'm not as clear. So it does matter. Is that
something that's prescribed or can you get that
over the counter? That one you can get over the
counter, actually. Yeah, you can buy it at any
health food store online. Yeah, like I said,
it's cheap, too. It's not expensive as far as
supplements go. So ideally, we'd test for the
gene and see if you have it and try the supplement.
But if you're just on a budget and you're like,
I can't afford to do this, you can try it on
your own. Obviously, this is not medical advice.
I am not giving you direct medical advice. But
in general, the studies show that the side effects
are very low. it's very well tolerated, especially
the supplement dose you're gonna get over the
counter. They do have now some crazy high dose
methylfolate, like 15 milligrams, and that's
super high. I don't recommend anyone starting
there because I do have parents that'll write
me and say, hey, we started this and kids bouncing
off the wall. And I'm like, no, no, no, that's
way too high to start. Like that will almost
always induce hyperactivity for a kid that's
naive to methylfolate, like that hasn't taken
it before. Yeah, so just be cautious. This is
why I tell people, you know, it is ideal to work
with a provider because You know parents think
oh we tried methylfolate and it was so bad and
it was just it was so bad for us And I don't
know what you're talking about But it was just
the wrong dosing and you almost always have to
titrate it start low and and and titrate up.
So, huh? Yeah, in my small community. I know
of someone that tried that and they have an autistic
son Yeah, and they said it just didn't work and
I'm wondering if it just wasn't given properly
Yeah. Well, and the thing was, so like I said,
there's the methylation deficits, and sometimes
you can notice pretty quickly, but if we're dealing
with cerebral folate deficiency, it takes a long
time. You know, the blood brain barrier has to
shuttle in this folate, and it's kind of an active
process. It's not a passive one, so it's not
just kind of diffusing like osmosis. You know,
it's not just traveling, so it has to be shuttled
in. So we find that it can take months. I mean,
I have patients that don't... you know, three
months, six months. Usually I will say we do
it for, you know, the high -dose folate, the
leucovore for six months. So before we're going
to say did it work or not. And if you look at
– and the number one thing I look at usually
is cognition. I try to find – I mean, there's
speech. Speech is a good marker because you can
say, hey, how many words was he saying? Oh, he
was saying one -word sentences or two, and now
he's on to three, and that's a good sign, right?
Anything – so we try to quantify it just so that
we know if it's working. But also cognition.
How's he doing in school? How are his grades?
Is he learning something new now? I like I know
with my son We've been bumping up the doses of
his lucavorn and I just I'm floored. I we'd stopped
it for a couple of years Because I've been doing
this, you know for my own triplets and my my
two boys with autism for a decade But I stopped
it for a couple of years thinking, well, you
know, it's hard. It's a marathon. So we just
stopped it because it was expensive and we didn't
have insurance coverage for it at the time. And
then we restarted it and he went from struggling
and, you know, barely making grades and kind
of a gen ed. special ed kind of setting, but
now he's in full gen ed and he's getting straight
A's. And I, I just, I, maybe it's the Luca Voron,
maybe it's not, I don't know, but it was a big,
dramatic change. And even as teachers are pulling
me aside, like what's this kid's really, what
happened? Like he's like the last year and I'm
like, oh, we started Luca Voron a year ago again.
So, you know, I am a huge fan and I see it in
other patients too. It's not just my story. So
like I said, it's been really popular online.
Everybody's been sharing these stories. I think
because Dr. Fry, you saw that article. He was
on CBS, I think. And so now it's just crazy because
everybody's like, what is this antibody and how
do we treat it? Nobody knew about it. And I love
that. I love it because You know that there's
this idea that we're finally getting to some
root causes There's an antibody that prevents
folate from getting into the brain. It doesn't
grow properly. It makes sense It makes sense
from a developmental standpoint and it it it
helps I mean there's I just presented we we did
at the talk a conference There was a big meta
analysis and it every time if there's been a
couple now and they're statistically significant
I mean it does show that it helps in double blind
placebo trials. So It's not just hearsay and
anecdotal stories. So it's pretty cool stuff.
And again, it's wrapping it around a pregnancy.
You can give it to mothers too. I have it. So
maybe that was part of my issue. I don't know
if I had it during my pregnancy. I mean, we didn't
even know about it back when I was pregnant,
but I wish I had, but I take it now. And yeah,
I mean, it's helped me a lot. Seems like from
the mother it could help her develop the placenta
is what I'm thinking. I don't know but because
she has a vital role with the placenta. Yeah
I mean it's it's critical I mean the studies
have shown that the developmental changes that
they've found in utero seem to happen yeah that
early development that first trimester so obviously
placenta develops within the first few weeks
of pregnancy um but yeah that first 12 weeks
you know the First trimesters use it first 12
13 weeks. So Yeah, make sense But yeah Yeah,
and in speech communication is a big Improvement
and I was thinking about the canner papers the
the initial canner paper. He had three non verbals
in there. Yeah, Richard Herbert in Virginia and
two of them at the time of the publishing We're
beginning to talk. Yeah, I was wondering I wonder
if that with this flenic acid is doing is like
helping the connections like between where they
key and broker just helping out the connections
there with the yeah, still connect areas. Yeah.
This is what I was imagining. Yeah, I mean, connectivity
in the brain is huge. And you have to have growth.
I mean, DNA replication and growth. I mean, just
the simple like, you know, terms that we learned
in biology, you know, I mean, it drives the whole
process. And so like I said, it Like, yeah, I
mean, when you have more connectivity, you're
going to be less focused on one particular area
of your brain, you know? And, you know, it's
hard, it's hard with autism. I mean, I wanted
to get, we'll get to this later, but I did want
to bring up those telepathy tapes because it
brings up a whole, I mean, it blew my mind when
I listened to it. I'm kind of half obsessed with
it because, you know, as my scientist brain,
I'm starting thinking, OK, so maybe it is the
connectivity. Maybe they don't have as much connectivity.
Maybe there's certain areas of the brain that
are more active than a typical brain that's working
all together. And so maybe they do. That's part
of the, you know, part of the savant -ish skills.
You know, I have so many kind of quack theories
on my own that I just sit at night at 2 a .m.
and come up with that I'd love to test, but obviously
we don't know. So, I mean, there's a lot of people
that are like, oh, it's hooey and it's not real.
And I understand skepticism. It's healthy to
have skepticism, but I love doing the opposite.
I'm like, well, what if it's true? I mean, we
don't know it's true, but let's assume it's true.
It's a science, right? And then take that hypothesis
further. What would that mean? What would that
look like? How would that happen? So anyway.
There's been independent studies on telepathy
outside of autism and non verbals. Yes Significant
papers to you. Yeah. Yeah, I don't know. It's
um K was on Joe Rogan recently. Yes. Oh, hi.
Yeah. Yeah. Hi Yeah, so I said they don't like
to be they don't like whenever their question
their capacity to think or question You know,
they don't they don't want to be proven wrong
and so forth So it's kind of a tough arena to
get into. It is, it is tough. And I think unfortunately,
I mean, or fortunately, I mean, that's where
the money's made, right? I mean, it's people
that are thinking outside the box that are, you
know, that are that are questioning. Why is this?
What is this? And that's where the breakthroughs
happen. It's not like, well, yes, this is what
we know, and we're just going to go down the
same road. I mean, you know, if it's working,
it's working. But in the case of autism, I mean,
the rates are increasing. And, you know, I mean,
my my kids tell me, you know, like, yeah, there's
a lot of kids. I mean, there's one in in my kids
classrooms, there's one in 20 kids, you know,
one every kid, there's at least a kid with autism
in each classroom. So, you know, and Yeah, and
so that's why I'm here. What are we gonna do?
What are we doing about it? Let's do something
Meaningful meaning like there's a delay or respond,
you know, right But it sounds like what you described
so far is like the pre -pregnancy Into the pregnancy
is kind of the same thing. It's just different
time points Essentially yeah, I mean I you know
like like for example with the dysbiosis and
I was I think about PCOS is in maternal PCOS
polycystic ovarian syndrome It's correlated with
Autism and offspring. I think it's like there
was a study that was like it was four times more
likely You know if to have a child with with
autism and so, you know, the question is okay,
so what causes PCOS, and that's typically a dysbiosis,
and there's hormonal involvement. And so what
are the hormones involved? And then that seems
to pass on to children as well, as far as there's
kind of correlating back to your cholesterol.
I know where you're going with this, is that...
There's a lot of hormonal abnormalities in kids
with autism, and I see it. I see that, you know,
there's kids with high testosterone. I see a
lot of kids with excess estrogen, a lot of cortisol
deficiency, and then we also see hypo -cholesterol,
you know, EMEA, like low cholesterol, and we
see that. I see it pretty frequently. I mean,
to the point where it's maybe, I don't know,
I would guess one in four, five. where it's lower
than the threshold that we talk about. And so
sometimes you'll see that in the moms, like low
cholesterol in moms can be associated with lower
cholesterol in the children, which can lead to
impaired brain development as well. So hormones
are a big deal to check as well. Yeah. Is that
the total cholesterol or what on the lipid panel
is it specifically? Yeah, so what we obviously
there I mean cholesterol is its own kind of functional
medicine Specialty and you can go really in depth
with adults and I've listened to talks with By
by Peter Tia and things that he really gets into
it. I love him, but I just for our purposes and
from what we try to base it off of the literature
specifically with autism So we look at total
cholesterol most of the studies look at total
cholesterol. And so that's what we base it off
of We don't usually get um, at least in the younger
kids a full lipid profile. We just get the total
and in our practice, I mean we typically treat
when it's less than 145 and I mean, it's it's
crazy because you know, like I said there is
a subpopulation of kids with autism that have
this low cholesterol and You can see it very
frequently. I mean In the mood disorders, you
know, the kids will be very grumpy. They will
usually be very irritable Moody up -and -down
mood swings, you know, they're just they feel
very emotionally dysregulated and Aggression,
you know, we'll see it and even But cognition
can be tricky. But when I see a moody child,
I'm like, let's check cholesterol. It's one of
the things we look at. And what's going on there?
Because I mean, cholesterol is such a tricky.
It's such a tricky topic because it's been kind
of Western medicine eyes for so long and we think
it's the devil and we're like this is just Cholesterol's
clogging arteries and causing death and I mean
it is an absolute essential nutrient for brain
growth I mean it myelin it's the nerves it causes,
you know So, you know transmission communication.
I mean, there's a lot going on with that, you
know with healthy fat with cholesterol and so
Yeah, I mean, we know this, and even in generalized
medicine, you can do a PubMed search, and it's
associated with other neurodegenerative disorders
like Parkinson's and Alzheimer's. If you do a
PubMed search like low cholesterol, there's several
studies that say low cholesterol causes Parkinson's
or has contributed to with Parkinson's or Alzheimer's.
So I think it's important that we really question,
like, well. where does it need to be, you know?
I mean, it's low definitely seems to be bad.
I mean, at a certain point. Now, you know, do
I let, I mean, kids run around with a total cholesterol
300. I don't know. I mean, maybe, you know, I
think at a certain point we need to look at both
ends of the spectrum. But, you know, there is
a point I think where too low is dangerous and
we see it. We see it in our kids, you know? And
we treat it. We treat it. It's actually really
cool. I mean, there is a supplement. it's called
sonic cholesterol, and it's actually cholesterol
capsules. I mean, we, ironically, everybody's
trying to lower cholesterol. And we actually,
we prescribe cholesterol to some our kids if
they're low on labs. And it helps, it helps like
sometimes stabilize mood. And it helps with sometimes
attention, sometimes cognition. But, you know,
and of course, too. we try to treat with food,
usually one of those capsules is equivalent to
about the amount of cholesterol in one egg. So
if the child's not allergic to eggs, then I'll
say, hey, let's get some free range, you know,
organic eggs and try to do two of them a day.
It's usually where we kind of start, but obviously
depending on the child and what they need. But
it's true in mothers too. So looking at cholesterol.
I think, you know, I just saw, and I can't quote
this, I just saw it on X and somebody had posted
this small little abstract, but they had an odds
ratio of disease development and they actually
found that, like the optimal cholesterol level,
total cholesterol to decrease overall mortality
was 220. was around the optimal range. And that
when it got below like 160, they found that the
disease ratio went up. And then when it got above
like 280, the disease ratio also went up. So
it was kind of this bull curve of like, you know,
cholesterol, like around 200 or 220 even higher
is, it seems to be really protective, protective
of the body and the brain and yeah, particularly
the brain. But it is responsible for hormone
production. So you need it to make cortisol.
and to buffer you from stress. Wow. Yeah, that's
why I had a bookmarked for later because... I
know, I'm sorry. I could have jumped into it,
but it was relating to hormones. Yeah, yeah,
you're fine. I'm glad we got to talk about it
because whenever I saw that post on Next, I was
like, whoa, that's... I've never considered that.
Yeah. Low cholesterol and this correlating with
these problems. Yeah, well just as a personal
story. I mean I can share I've had I've always
had my family we have high cholesterol like the
hyper familial cholesterol and I You know, it's
always been a little high. I don't know like
220 maybe 230 You know, it's been a little always
a little over 200 and my doctor's like even when
I was like 19 You know and my doctor's like that's
kind of weird. You're kind of young for that
because I've never been terribly overweight and
so When I got married and we had our wedding
in Cancun, I did what all women do. I lost all
this weight and I went on this ultra low calorie,
low fat diet and I lost a bunch of weight. And
I don't know, I think I got my BMI down to like
20 or something. And I remember my doctor. Tested
my cholesterol and he's like, oh wow, this is
the first time your cholesterol has been normal.
I congratulations and I'm like, well, yeah, that's
great But I haven't I haven't menstruated in
over a year and he's like what so I know it's
a little personal But I actually stopped when
my cholesterol got normal my hormones shut down
and I just stopped menstruating like for my body
Getting to that lean body mass BMI of 20 21 getting
my cholesterol normal my hormones shut down and
they even did like a They did a progesterone
challenge test for me. Like, well, maybe you
need progesterone, but not estrogen. And I failed
it. He's like, you don't even have any hormones.
Like you don't have enough estrogen or progesterone.
And he was kind of baffled. I remember he was
sitting there and I'm like, I don't know, but
my body just knows. And I wasn't eating enough.
And as soon as I started eating more and going
back on a normal diet, then, you know, I started
menstruating again and everything was in. And
then my cholesterol went back up to 230 and he's
like, well, here you are again. And I'm like,
Yeah, you know, I don't mean so I just it was
a lesson for me like I have to listen to my body
my body You know is telling me and you know,
and I remember back then too, you know And there
was probably my thyroid wasn't happy with me
either. I mean I was cold I was a little more
fatigued I wasn't as like energetic and I'm like,
oh shoot like I so I kind of dumped that cholesterol
paradigm just off of my own personal story a
while ago like cuz they you know And my family's
like that too. Like they all kind of have it.
And so maybe it's buffering toxins. Maybe I need
more for my cortisol because I'm a high energy
person, you know, I mean, maybe, you know, I
mean, I've, I don't know. I mean, I could, I
could make theories, but my whole point is yeah,
cholesterol is definitely not the devil. You
definitely need it, you know, and we don't need
to lower the, we don't need to lower everybody
as low as we can get to make the, that's, it's
not, I don't think that's a picture of health.
You know, I think that's what health looks like.
The ranges are pretty suspicious, I think. Maybe
I shouldn't say suspicious. It's just very questionable.
Yeah. Like the new ranges. Yeah. Yeah. Yeah.
I mean, it's pretty aggressive. You know, when
I have done primary care, I... You know, I try
to just be reasonable, you know Like you said
there is a point where I think you should treat
and you know If it's getting up to 300 and there's
risk factors and things that can okay. Let's
let's look at this but But yeah, I mean some
of the the recommendations are pretty low for
people if post stroke or heart attack It's you
know, they're getting their total cholesterol
really low. So yeah Makes me worry. Yeah. Yeah,
and just It's suffering so fading with vitamin
D I mean, it's optimal. That's the way it should
be. Yeah. That's what it's supposed to be doing.
The 7 -DHC, I think. 7 -DHC and the vitamin D.
I like my hormones. I mean, we need hormones.
Yeah, I like my cortisol and my estrogen and
my testosterone and testosterone and vitamin
D and all, you know, yeah. I mean, it's all good.
It's all good. We need it. I'll take it. What
are some of the symptoms of dysbiosis? Could
you explain that to me? Yeah, yeah, that's a
great question. Well, you know, and we see it
like most kids have some form of dysbiosis. And
what does that mean? I mean, it's this kind of
weird word. It just basically means something
is kind of atypical or off about the microbiome.
So it's a blanket all term, but, you know. Studies
have shown like so autism is interesting It has
its own kind of metabolic profile in the gut
like this own microbiome profile so they find
that what they they can almost look at neurotypical
kids and then look at their microbiome and look
at autistic kids and There's a different they
can see the difference even just by looking at
this little fingerprint of bacteria And there's
several key things that are different a lot of
studies. There's been several that have shown
that it's It's kind of very in -depth in microbiology,
but there's something called formicides and then
bacteroides, and these are kind of larger groups,
larger genre of bacteria. And most people in
the Western world have more formicides than they
do as bacteroides. And that's actually... in
general, buffers for carbohydrate metabolism.
It buffers. It's more anti -inflammatory in general.
But with autism, there's this skewed ratio of
having this increased bacteroides. And so there's
a lot of theories, and it all is, from what I
have understood, just theories at this point.
Maybe they don't digest carbohydrates as well,
or maybe, you know, who knows? I mean, maybe
this is what inflammation does. I mean, I don't
think they're really I haven't read anything
that we know what the root cause is, but there
seems to be a fingerprint. And so what we find
is that there's a lot of overgrowth of these
pathogenic bacteria at a much greater rate than
a neurotypical child. So, you know, you'll have
oftentimes these bad clostridia, like C. diff,
clostridia difficile overgrowth. And so you asked,
to your point, like symptoms you might find.
And usually, again, with a lot of bacterial overgrowth,
I'll find diarrhea, you know, I mean, but, you
know, any kind of floating stools, malabsorption,
like, so you see actual, like, maldigestion,
so you'll see food in the in the toilet, you
know, in the stool. You'll see a lot of bloating.
Bloating is probably the number one symptom I
see in young kids. You won't necessarily know.
because sometimes little kids kind of have a
little belly anyway, right? But kids that are
what they call posturing, so if they're leaning
over a table, and I can't show you here on the
video, but just kind of like pressing on things,
like they'll usually go to the corner of a table
and push their belly on it, and they're kind
of scrunched up. Or just curling up in a ball,
like they'll often be pressing on it. And not
usually with their hands, ironically, I don't
know why. They're usually pressing on it with
an outside object, like a couch. or something
and they'll lean on it. And so that's kind of
a symptom of bloating dysbiosis. And you can
see that even in little babies, when a symptom
is that the babies will be in that fetal position,
they'll be on their, they'll be kneeling with.
Like I said their knees on the ground and they'll
kind of be like this and their butts in the air
if you've ever seen how they kind of push they
kind of scrunch up and have their butt in the
air and that's kind of a sign of fetal bloating
and digestion even you know under kids under
one year old and so and obviously gas is big
with you know you'll have the gas the bloating
the burping and a young baby a lot of reflex
and those readings are I mean they happen on
occasion and we all get those but if it's a chronic
daily thing then you need to check it out, you
know? Yeah. So again, adults, yeah, it can be
any of those. Yeah. Yeah. For children, I had
a question about how do you get the child, especially
an autistic child, even nonverbal, how do you
get them to convey what is actually going on
with some of these symptoms? It's hard. It's
hard. And, you know, that is a big Complaint
I hear all the time of parents like how do I
know how do I know and so and you don't always
know I mean Again, there's the pressing on the
belly. There's frequent gas, but I'm always assuming
You know when I hear of a lot of self -injurious
behaviors, we usually test So I mean and personally
like I said with my son on you know at the time
he was too and he regressed and I know it was
his stool totally regressed with him. I mean
he was having fairly regular bowel movements
and then it started to get mushy and then you
know smelly and then he was smearing it and he
stopped talking and then he was smearing it all
over the wall like he and you could tell it bothered
him because he would just reach in and be like
he wanted it off of him you know and then he
just then it was gross and he just he just was
it was bothering him he was always having his
hands in his pants and um And so I, you know,
I just kind of knew, okay, this isn't normal.
Like he regressed, but his stool also regressed.
And, you know, I had to treat that and we had
to do something. Cause it just, it seemed he
didn't really want to eat. He started, he started,
you know, refusing food that he had normally
eaten. So again, picky eaters is another big
sign. If they're not wanting to eat, you know,
food versions, I'm thinking, okay, what's going
on in there. And so, there's a lot of reasons.
I mean, anything whether they're not, you know,
their stool's abnormal, they're not eating, but
yeah, oh, and so my point was, the self -injurious
behavior, as part of it, when he regressed, he
would just start hitting his head against the
wall. And this was out of nowhere, and I just
would see him, and he'd just be banging it. And
I mean, as a mother, you're like, holy, like,
what do I do? You know, it's so distressing.
But I just had this sense that, intuitively,
that he was in pain. It looks like pain. Is there
something bothering him? So when you think pain,
I always think first, the gut. Something's going
on there. So yeah, self -injurious, definitely
we look at that. And it can be hard. It's very
hard. Some of these kids, it's hard to treat.
It's hard to figure out, because there's different
kinds of dysbiosis. Like I said, there's some
kinds of... bacterial overgrowth and there's
fungal overgrowth or both, and then they'll have,
you know, C. diff on top of it. And, you know,
it can be very complicated. But, you know, we
have to try and piece it apart. I mean, it's,
it's, in my opinion, I'm, I'm, I'm very aggressive
with the gut, because I think, just in testing
and treatment, because it's like, if you leave
it, it's not usually, I mean, sometimes it gets
better if there was a, if there was a, like,
say they get a virus, like my kids, like, they
got the flu a few weeks ago, and, you know, they
didn't want to eat, and they kind of vomited
a few times, and, but, you know, now that they're
better, it seems to be getting better, but, you
know, if it's a chronic issue, then you have
to address it, otherwise it won't resolve on
its own. It may not. Sometimes it does, but it
may not. Yeah. Gastrointestinal problems is there's
like three comorbid problems that are so common
with autism and gastrointestinal is one of those.
Yes, autistic child or even adult will have gastrointestinal
problems. Yeah. And I mean, the first thing that
we do when we when I see patients is I, you know,
I ask them, how are you, how are you pooping?
And almost all of them are constipated, not all,
but maybe. three -quarters, maybe two -thirds.
So, you know, getting the bowel movement is key
to getting things started, to just, you know,
removing toxins. These kids, either from the
inflammation in their gut or the mitochondrial
dysfunction or just, you know, not enough good
bacteria, you know, sometimes the gut will just
shut down. It just stops moving. The peristalsis
slows down. And then that's when they get really
sick because they're not digesting. They're not
kicking out toxins. The body's meant to poop
every day. And if it's not, they don't feel well.
So it's like the first thing we talk about at
a visit. Like, how is he pooping? Because it
is just that important. It's hard to recover
a child or make a lot of improvement if you're
not working on the gut alongside other issues.
It's so fascinating how that correlates there.
And I think vitamin D is involved, if I had to
guess. It's a factor. Yeah, because the vitamin
D provides us a cage on our surface. That way
all of our electrical processes on our insides
can run optimally. And I think it's a big problem
here. Yeah. It's like the energy is not being,
I don't know, it's just not working because of
the low vitamin D. Have you ever seen someone
with autism with normal vitamin D? Um, yes. Um,
I mean, have I ever? Yes. Yes. Um, it's not common.
I mean, it's not common. I mean, almost all I
would almost all of our patients are on vitamin
D. I mean, I would say 90 % of them. I mean,
it's, it's, it's highly correlated with low vitamin
D. It's one of the supplements that I've given
my kids and we've taken, I've taken and pretty
much everybody is because it seems to be your
diet. I mean, it is a, you know, are we not getting
enough sunlight? Is it an inflammatory process?
Is there not enough hormones, cholesterol? I
mean, is there, I don't know. You know, it seems
to be that is not autism specific. I mean, I
think that most people I find are vitamin D deficient
even in a primary care setting. So do I see kids
like when I say that they're normal, like we'll
test them and their vitamin D might be 35, you
know, or 40. Um, but we still put them on it
because we want to get them in that optimal range.
So, but I mean, I've seen kids with vitamin D
of like two, I mean, I've seen it like, holy
cow, like you have no vitamin D. Um, and so,
you know, and it helps. I mean, there's studies
that show that vitamin D just in and of itself
as a supplement improves overall autistic symptoms.
I mean, um, so. You know, yeah. Yeah, I don't
know. I mean, I try and get my kids out. I try
and get sunlight. I think I think I'm huge into
this. I can tell when my daughter's low. It's
she has, you know, they have like this, this
kind of a grayish tinge. It's like this kind
of transparent kind of sallow and I'm like oh
no we need vitamin D and sunlight and you know
so I start I start getting on them you know and
you can see it in other people it's kind of this
this pale transparency of their skin and that's
when I see that I'm like okay that's either zinc
deficiency or vitamin D or probably both um but
you know a lot of autism a lot of children with
autism they're very very pale yes It's unbelievable.
Once you see it, it's like every one of them.
It's so powerful. But I want to ask you about
the vitamin D supplementation. Yeah. What kind
of doses are you doing? And are you using anything
like K2 or magnesium alongside with it so it
kind of synthesizes correctly? Yeah. How long
does it take for you to see results? Yeah. depending,
but I do like to recommend vitamin D3 with K2.
Usually in most people, most kids, I'll start
at around 2000, I use a day of the vitamin D3.
Different brands, I think, have different potencies,
and I like the ones that are fat soluble. So
the ones that are actually, you know, either
as a liquid dropper or in a fat capsule. like
those gel caps, it seems to be better absorbed
and it seems to raise the levels higher, so quicker.
So if we're trying to get them higher, then I'll
put, you know, and quickly I'll put them on a
liquid drop. And yeah, I mean, it can work fairly
quickly within weeks if, you know, if you're
using the right product. I mean, if you're taking
it for three to six months and it's not increasing,
you're on the wrong product in my opinion. Is
it a brand? Is it like the folinic acid where?
Well, not necessarily folamic acid, but with
the folate, where there's various options, is
vitamin D the same? Mostly, I would attribute
most of that to production quality. Actually,
the standardization of supplements is... pretty
much non -existent. So, you know, you don't really,
it's the Wild West. I tell everybody, like, you
don't really know what you're getting. And so
that's the scariest part, I think, about supplementation.
So, you know, I try to use, like, I buy all my
stuff on, you know, Fullscript and they have,
like, they're supposed to have had, if you believe
them, third -party verification where they do
verify their products or some of their products
to have, to actually have what they say contains
in it. because the FDA doesn't do that in the
United States. So I think that's mostly it. It's
like, just because it says it's in there, it
doesn't mean it's in there. I mean, you can look
at some of these. Like I used to look, I think
it's closed now. I looked recently, but there
was a website called Labdoor and they would review
common supplements for actually what was in them.
And I used to spend a lot of time on there just
in a lot of things like those Centrum. you know,
one a day. I mean, it has nothing in it. It's
just like magnesium stearate. It's just, it's
just filler. And you read the actual analysis
from the labs. You're like, holy cow, they're
just selling sugar pills and people buy them.
And it's really sad. So, you know, so I think
it's just the quality. So if they're taking something
and it's not working, let's switch the brand.
And, you know, there are some good ones out there.
And people should stay away from proprietary
blends. Whenever there's like a couple of different
ingredients listed and it's like, five grams,
but there's like six, eight ingredients. Listen,
you don't have, you, you have no idea how much
of each ingredient is making up that fiber. Correct.
I don't buy anything with the proprietary blend.
I don't know. I'm like, no, you either tell me
what I'm taking or I'm not taking it. I want
to know exactly what I'm taking. Thank you. Yeah.
Just abbreviate the crucial things and you know,
the filler, like you said. Right. Right. So you
got to be careful. You do have to be careful.
But I did actually, and I started, I did want
to bring up something that has been on the dysbiosis
and the gut topic that's been going around a
lot online. And I just wanted to talk about as,
you know, the fungal overgrowth is a big deal.
And a lot of people are sharing these studies
of itchoconazole, like curing a kid with autism.
And everybody was commenting, this was a few
weeks ago, was commenting on it, sharing it.
And I was trying to kind of jump in there and
contribute. And I do see, and so let me start.
Normally I test for most of my fungal markers
with an oat test, like we talked about earlier.
If I see more than like one marker, so Arabinose
is typically, there's a marker on there called
Arabinose, it's typically associated with Candida.
Or just regular yeast. But a lot of the other
ones on there are like mold byproducts. They're,
you know, they're like Aspergillus or, you know,
Fusarium. different kinds of mold byproducts.
So you want to treat those when you see them.
And so I do, I do treat that and, and there are
different, and it is, I think, important. And
with my own kids, I saw, um, like I, I think
I told you last time, I think part of their regression
was, it was multifactorial, but there was definitely
mold in our house because we were remediating
it inappropriately. We had a leak and blah, blah,
blah. And so, and I think they got really toxic
from fungus. And so I had to do, you know, clean
out, but we ended up back then, I didn't know
what to do. I was pouring over trials. We ended
up doing grapefruit seed extract because I was
like, I can't, I didn't have a, you know, I wasn't
doing this yet. I wasn't in the functional medicine
space. Um, and it really helped. Like it actually
helped. And I don't think it's the cure all for
everybody, but I know when I treated the yeast
at my kids at that age, treating the fungus,
um, They calmed way down. The behaviors went
way down. Just the repetitive, you know, stimming
and the self -adjurious stuff. I mean, and we
ended up, we didn't end up going on intraconazole,
but we ended up on nystatin, which is an antifungal
that really just stays in the gut. And it's better
for yeast than it is. It's not as broad spectrum
as some of the other antifungals like intraconazole,
but We were on it for like two years, and I couldn't
get my kids off. I'd stop the Nystatin, and then
the behaviors would come back. And then they'd
start spinning in circles and running around
the house, you know, screaming. And then I'd
go back on the Nystatin, and then they'd just
sit there and happy, you know, like, just calm.
So, I mean, we were on it forever. And so it
happened. And I have patients like that. So I
do, I want to encourage parents like, I think...
Don't think that that study is rare. I think
that a lot of kids do have fungal overgrowth
specifically I think mycotoxins are a big deal
And I we anybody that's really treating autism
in a functional medicine space You know needs
to needs to look at fungus and like how to get
rid of it, you know And and it's not always killing
it. It's it's not always like oh you need this
high high dose antifungal forever A lot of it's,
you know, kind of detoxing, you know, moving
out of the mold, remediating your house, you
know, eating, going on a low mycotoxin diet,
you know, like not eating moldy foods like bread
and juice and things. I usually put kids on a
short course of binders. I'm a big fan of binders,
like not forever, but a lot of them, they can't
always process these mycotoxins. And so they'll
just keep recycling them in their body. And then
their toxic burden just gets to a threshold that
They start regressing and breaking down. I mean,
I think that's what kind of happened in my household
Binders can help be helpful to get rid of some
of the toxins. What are those? What binders?
Oh, it's a good question. Um, so basically So
they're Insoluble basically the products that
don't get absorbed into the bloodstream. So the
most classic example would be activated charcoal.
So charcoal would be a binder, right? So if you,
in Western medicine, like if you overdose on
certain poisons, right, they'll give you activated
charcoal, even in the ER. Like if you can't,
if you're past the vomiting stage, like sometimes
they'll try to like induce you to vomit, but
if it's been too long since the ingestion, they'll
actually give you activated charcoal. Say you
drink like I I'm not I'm not good at my ER medicine
anymore But I know that there are certain toxins
that have an affinity for charcoal So they'll
basically we've been doing this in Western medicine
for a while And so they'll bind it and then you'll
just poop it out You can't you don't absorb it
in your GI tract and then it comes out in your
stool and so you can rid your body of GI toxins
And so this is really really helpful for kids
with really different kinds of toxicities It's
good for mycotoxins It's good for even metals.
I mean, this is why everybody online is talking
about zeolite Well zeolite the binder and it's
a it's a pretty potent binder especially I mean
if you get the right brand and especially for
Metals, you know, but it can actually zeolite
binds a lot of mycotoxins as well. So I I do
like to do a trial and some parents say that
it was better. I mean I have parents you know,
that say, hey, when he's on this binder, like
he's got better eye contact, he's more focused,
he's calmer, you know. And so, like I said, that's
kind of part of the treatment protocol if you're
dealing with a dysbiosis, in my opinion. But
you definitely don't want to ever give it without
starting to move the bells first. So. you know,
like basically if the child is constipated don't
give a binder because it makes constipation worse
and then it'll just sit there this big ball of
Whatever you're giving zeolite charcoal Bentonite
clay, you know, there's different ones. You don't
want to do it Until they're having daily bowel
movements So that's my big warning to parents
and I'll make sure if you're gonna give your
kids any kind of binders Have daily bowel movements
first That makes sense. Because it's popular
online. Everybody's buying them. Everybody's
trying them. And I'm all for power to parents
and self -advocacy for your kids. But yeah, you
got to make sure that you're not making them
sicker because they haven't pooped in like, I've
had parents that are like, oh yeah, he hasn't
pooped in five days and we're giving zeolite.
And I'm like, no, you can't do that. Stop. So
usually we recommend some kind of magnesium and
high dose at night to get the bowel movement.
That works the best. There's magnesium citrate,
there's magnesium oxide ozonated in the form
of like, it's called oxy powder. That's my favorite.
But you can do high dose vitamin C. I have, you
know, there's obviously the senicots and things
like that that are stimulant laxatives. But yeah,
get the bowels moving first before you do binders.
So I'll say it three times because I've just
heard, you know, I've heard a lot of parents
with issues. And again, it's like, it's not the
binder's fault. It's not that it's the wrong
treatment. It's just without the knowledge of
knowing how to implement it. It's valuable. And
good for whoever named the binders binders because
it's just binding. Right. Names can be complicated.
Well, I think it's a colloquial term. I mean,
I don't think it's actually like an official
term. I don't even know. But it's just everybody
uses it. So we all just kind of use it. And I
have a couple that are my favorite. you know,
some are more gentle than others, like charcoal
is pretty harsh. Charcoal is very, like, it's
very nauseating, and it can be more constipating
than other ones, so. But, you know. Yeah. So
anyway, so yeah, so treating the mold, binding,
eliminating, getting the bowels moved, moving
out of it. maybe you need some antifungals, talk
to your doctor about it, you know, find a good
doctor, because you don't want to be trying to
find itchoconazole online. You know, some of
these studies come out, and I always just worry
that parents are like, oh, I'm going to buy it
from India and then try it. I mean, the stuff
that the study was very, the itchoconazole was
very hard on the liver. And it can actually increase
estrogen and over long term use. I mean, short
term, it's fine. But, you know, just I love I
love going on this podcast to kind of like clear
up. You know, like don't do this, you know, because
just just talk cautionary tales, you know, because
like you said, how do you know if you don't know?
I mean, I only know because I got into this for
my kids. So ten years ago. It's very valuable.
Your information is very valuable. Oh, thanks,
Ryan. I always enjoy talking to you. Thanks.
Is there anything else related to the GI that
we haven't covered that you might think could
be informative? No, I mean, Well, we talked about
the fungal markers, getting a note, treating
those, getting a stool test, treating their bacteria
there. Clostridia can, the C. diff and other
clostridia strains can be associated with a lot
of aggression. So my last like kind of statement
would be if you see a kid that's just really
aggressive, like hitting people, biting people,
and especially if it seemed to happen overnight
or it's just... There's triggers. Look at Clostridia.
We do see that it seems to make kids very angry
and very depressed, either angry or depressed.
But that particular bug seems to cause mood issues.
And so I think of some parents, I just don't
want you to think, well, this is my child. He
just... bites people and in reality there's you
know there's a there's a bad bug in their gut
so that you really got to look at so there there
are several different types of dysbiosis and
again I we will treat them and usually for the
C. diff we do use antibiotics because you really
got to get rid of them it's a spore forming bacteria
so that means that you know when you kill the
kind of adult form of it It'll form a little
sport and just hang out there. It'll go inactive,
but it'll just wait. It'll just sit there and
then basically wait for it to bloom again. So
it forms these little... Yeah, it just kind of
seeds itself in there and it doesn't want to
go away. So you have to treat it usually for
several weeks. Sometimes you have to do several
rounds. Give it with an anti -biofilm agent.
I mean, there's ways to treat it, but it is a
difficult to treat bug. But treating it... you
know, my son had it for a while at four and we
were going through cycles and yeah, he was just
really Grumpy like really grumpy and now he's
just happy as a clam So I mean we finally got
his gut on better track and I really pushed the
second thing about the the the gut stuff I'd
like to say is just that in general I try and
push a lot of good bacteria and there's some
you know, some practitioners say well, this is
gonna increase serotonin, or this is going to
cause a dysbiosis in and of itself. And that's
valid. I mean, I think there's room for discussion.
But I got tired of treating with my kids with
antibiotics. Like, we were doing these cycles
of, like, I'd treat them with antibiotics, and
then they'd have opportunistic infections, and
then they'd get fungus -y, and oh my god, it
was just this cycle. So I started just... drowning
them in probiotics basically and I'd rotate them
and give them different ones and we do some kombucha's
and I do some like this bio -K that's an active
probiotic like gut shot. We do capsules, different
strains. I've tried all different strains and
you know I find that actually helps them more
long term. Like now we don't need as much antibiotics
like so I try and push good bacteria versus killing
when I can for the long term. Okay, so in general
that's that's all okay. I always heard that Anytime
you're doing antibiotics, you should do a probiotic
as well I don't know if there's any truth to
that but the source of it is this very he's very
good. So yeah kind of Believe you. Yeah. No.
Yeah. I that's in general a good a good rule
of thumb Okay Because again the gut knows what
to do. I mean it we had we've had If you have
enough good bacteria, they actually produce,
it's really fascinating science. They produce
a ton of antimicrobial compounds that kill other
bad bacteria and they reduce inflammation and
they increase motility, they increase butyrate
that fuels the gut. So if you have enough good
bacteria, it will crowd out the bad. It really
will fight the bad for you. So these kids, a
lot of times they just don't have enough good.
And I see it all the time when we test them.
They're missing lactobacillus, they're listening.
missing bifido, they're missing key E. coli strains
that are normally found in the gut, and then
they get these dysbiosis. So, you know, that
instead of treating the gut bugs when we increase
the, you know, treating the bad bugs, we give
good bugs is always the goal if we can. Yeah,
yeah, okay. It's incredible information. Yeah.
Very, a lot of good takeaways so far. Do you
want to pivot over to the telepathy tapes? Oh,
I you know, I I don't know really what I want
to say about it I just I just wanted to talk
to you about it because I just think it's fascinating
and like It sparks my interest so much and I
don't know even how to how to wrap my mind around
it Like I want to get into research regarding
it. I like I want I wish and I'm putting it out
there in the universe Because I'd love to I love
working with the autism population and I really
would love to try and You know understand, you
know, like I said, I've come up with all these
wacky theories like we we know that kids Studies
have shown that in a lot of meta analysis of
these huge, you know populations copper Dominance
is huge in the autism spectrum population. So
a lot of these kids have copper excess like probably
most it's one of the number one metabolic Markers
associated with autism. So I mean maybe I'm thinking
okay copper. What do we do about copper? I mean,
we know a lot of things about the metabolism
But like what if they're little conductors what
if they're somehow generating, you know, I don't
know I mean, you know drawing electricity drawing
some kind of magnetism. I don't understand it
I know copper's not magnets per se but you know
Maybe the metallopathies that we see in autism
contribute to these skills that they have Again,
I start going down rabbit holes. We know that
a lot of them have a lot of fungal overgrowth
in their gut and sometimes in their sinuses and
things. Maybe it's more like the psilocybin deal.
Maybe they're connected to some mycelium network
because they have a lot of fungus grown in their
gut. Maybe they're getting knowledge that way.
These are the things I contemplate at night.
When we talked about maybe it's just because
certain parts of their brain are Extra active
more than the normal brain, you know, like we
um, I think we mentioned last time that dr Amen,
you know with his spec scans that he looks at
the brain calls autism the brain on fire in the
sense that it's It's just hyperactive more than
any other brain scans that in a population he
finds so maybe it's just the activation of the
brain In a in a I don't know. I don't know. I
mean, what are your thoughts on it? I'd love
to hear what you think The first time I really
got into telepathy was from a Rick Rubin podcast.
And he was a very valuable neurosurgeon and a
neurobiologist from Stanford on it. And they've
talked about this. And this is where I found
out that, well, telepathy has been published
in well -respected journals. It's not like it's
something new. And this was before the telepathy
tapes came out. They were talking about water.
and quantum coherence, and how water can signal
and communicate distal without axonal connections.
It's the water that's doing this. And a neurosurgeon
mentioned that there's a guy named Del Gouche,
or something like that, Del Gouche. And he took
vibrations of water, and he could replicate the
DNA exactly from across... from US to Europe.
So I'm thinking like with autism, because there
is this dysfunction and it's the process of like
the sensory and the movement of electricity is
off. It's so wound up because of the bad connections.
I'm wondering if it's just the the sensory processing
and just being aware of the environment is so
accelerated here because of there's no proper
distal connections being how we would sensory
process, or sensory perception processing, how
it's just one connection to the other. If they
can just do this because of what you were mentioning
about how it's just that brain on fire, essentially,
and then the water vibrations happening. or like
local areas that aren't allowed to connect properly.
I don't know if there's too much going on or
if it's just the same amount. Let's just say
as a whole, you're processing this energy. If
the autistic person with telepathy is just bound
at one local area, and that allows this recruiting
of different connections and with the environment,
instead of that overall whole electrical capacitor
here being just moved normally through axons.
I don't know, but that's what I think about whenever
I think about telepathy. Yeah, I mean water is
that that's an interesting theory just I I mean
we hear a lot of people that talk about oh I
got this idea in the shower or I you know, I
you know, I You know that the normal people kind
of get more Intuition from being in water. I
don't know. I don't know. I mean Yeah Definitely
it could be the hyper focus in the brain. Like
you said, you know when when when Mean we we've
known when people lose other senses, right? Like
if you're if you're blind and you have kind of
this hyper Sensor hearing, you know, I mean,
you know bats for example, obviously it's not
humans But they have echolocation and they may
have different organ receptors I'm not sure but
but nevertheless even in humans. We know that
people that lose senses will have extra sensitive
other senses So, you know, maybe it is the lack
of speech that allows their mind to calm you
know in a sense that they're, they're, they're
focused on certain areas of their brain that
the rest of us are just kind of running around
in our frontal lobe, pay the bills, okay, make
lunch, you know, and they're just like, not using
that part and they're focused on, you know, this
extra part. Yeah, there's some areas known with
autism, post -mortem studies and whatever that
the, that the, that the areas related for or
that sensory integration is there. abnormal.
Yes. These areas, you know, that takes multiple
senses, you know, and makes sense of them and
goes off and recruits other distal connections
through the brain. These areas are bad in autism.
Yeah. Yeah. Well, I would love to get involved.
If you ever hear anything, Ryan, any kind of
studies or anybody working on it or anything
like just let me know because I'd love to somehow
jump in and get involved. Would like to see video
footage of it so I can really see You know, it's
hard for me to listen to the telepathy tapes
because I can't see it so I guess you could go
on the website or the I guess I guess I guess
they do have it for viewing. I think if to pay
for it Yeah, yeah, there's like I know that she
mentions it sometime so I'd have to do a Google
search But there are videos like associated with
the testing But I went I went looked on the website
and I think you had to pay for it and that's
unfortunately where I stopped so but But yeah,
anyway, that's just that's my two cents and that's
did I did I cover any of your questions? Yeah,
I think so that it was a very fantastic exploration
through the GI Yeah, I mean there's a lot to
talk about. I mean, there's you know, these are
just kind of baselines, but definitely I appreciate
you having me on I really love educating just
people and Yeah, I really want everyone to know
I want everyone to know what I know I wish I
could just like transplant my knowledge just
because you know, it's like it things because
it took me ten years to get here and I wish I
could just download it because Yeah, so I'm happy
to share it because you know, there's so many
things that it there are you know, some aha moments
I know I say it on every podcast yours, but there
is a lot of hope and there are things you can
do and so I always try and translate you know
that that message um yeah just try it do something
find somebody if you're feeling inspired if you
have a gut feeling like I don't know I think
it's I had a parent that came to me he's like
I think it's metals I think my son's lead toxic
and I'm like why do you think that and he's like
I don't know and so we we did a test we did a
chelation challenge test because he was and he
was right the kid's lead was like 54 times the
upper limit Like, wow, your kid is actually full
-led. So if you have this intuition about your
child, like, I think it's this. It's certainly
worth investigating. I always, I mean, I humor
everybody. Like, yeah, I assume everything that
everybody tells me is true. And then I kind of
work backwards. And then I'm like, well, it doesn't
look like this at all. It's actually this. But
we always investigate it. So follow your gut.
I've done that several times with my kids. And
half the time, it's right. No, it's not always
right. But my parents are always right. um without
any bias there it allows you to kind of zoom
out and take a look at the full picture i think
whenever you know you're listening to these other
people sometimes that's people have a hard time
doing that especially if you're like a specialist
yeah it you know i i just trust i just trust
parents intuition and it you know, I think that
they, I mean, parents are deeply connected to
their kids. Like don't let telepathy tapes, like
there's this deep connection. And a lot of people
have, you just kind of like most moms know like
something's wrong. You know, I mean, when you're
connected to your child and, and you know, and
then I am the objective party that says, okay,
let's assume that's true. Let's look for it.
Let's test for it, you know, because I don't
ever, you know, you want to have objective data
too. And so that's good. It validates what they
know. And then we're moving forward with a good
solid plan. Cause yeah, if I had attested this
kid and we We did a chelation and there was nothing.
I'd be like, well, shoot, I don't think, you
know, you may be off, you know, and I, and I
wouldn't proceed. I would say, you know, I don't
think we should be doing this anymore. It doesn't
seem appropriate necessarily. And you can argue
that maybe we were using the wrong substances.
You know, I have some parents with, oh, no, well,
it's still in there. And that might be true too.
We're living in a bubble. So maybe I, there was
the wrong dose, you know, maybe the wrong test.
But, you know. It just that point is just we
go down the road because a lot of times we find
stuff we do Oh cool. Look at that Paris knows
so much. It's so fascinating. Yeah. Yeah Yep.
Well, thanks Ryan. Thanks for having me on again.
I super appreciate you And like I said, I just
want to tell listeners this none of this is medical
advice. I work I work at Rossignol Medical Center
Dr. Rossignol is my supervising doc there and
he's always he never wants He always wants me
to tell everybody, no, this is not medical advice.
Talk to your doctor. But we're a great center.
We have like three locations in the U .S. and
we're seeing new patients. But if you just want
to contact me, I'm on X. I have a website personally,
www .nicholeryncon .com. You can contact me there
as well. So yeah, I'm available and I'm open
for any discussions. and opportunities too, for
further research. Oh yeah, and the research,
yeah, we're always doing research at our clinic,
so. And I'm always looking forward to your research,
yeah, so. Yeah, I'm always looking forward to
what your group's pushing out. Dr. Fry is coming
on next week as well. Oh, is he? Oh, great, wonderful.
He's gonna come on for a second once a year.
I'm like so blessed that your group here is so
willing to come on and share. Yeah, he's a good
guy. He's a wealth of knowledge. And he's my
he's the PhD, you know, he's he'll tell you all
the nitty gritty about the science. So I, you
know, I appreciate him a lot. Yeah. It's great
work from you guys. Thanks. Thanks for coming
on. Thanks, Ryan. We'll have a good week. Hopefully
we'll we'll chat soon again. Let me know. We'll
have to figure out our next topic. Yeah. Okay.
Thanks, Ryan.