1 00:00:00,000 --> 00:00:14,000 Welcome to From the Spectrum Podcast. This is a podcast about autism. It is my goal to explain what is autism. 2 00:00:14,000 --> 00:00:22,000 I plan to use a mixture of scientific literature, personal experience, and opinion. 3 00:00:22,000 --> 00:00:35,000 With opinion, I will explain why, I fill the way I do, and give examples. I will provide links to various references for each episode. 4 00:00:35,000 --> 00:00:41,000 For each episode, we will discuss various aspects of autism. 5 00:00:41,000 --> 00:00:56,000 For today's episode, we will briefly, briefly discuss physical theories in atoms and molecules. Essentially, we will discuss energy. 6 00:00:56,000 --> 00:01:13,000 We will explore quantum biology, quantum coherence, quantum thermodynamics, water, DHA, and expand on NFKB. 7 00:01:13,000 --> 00:01:25,000 Remember NFKB from Dr. Hannah Stevens. From that episode, you can find a clip from the NFKB discussion. 8 00:01:25,000 --> 00:01:38,000 The goal of today's episode is further explain energy and transferring energy from the environment across our biology. 9 00:01:38,000 --> 00:01:45,000 Remember previous discussions about electrons and some protons. 10 00:01:45,000 --> 00:01:57,000 Remember Dr. Richard Fry letting us know that the whole reason we breathe is so cytochrome-sioxidase can function. 11 00:01:57,000 --> 00:02:08,000 This produces water in the electron transport chain, which is the fourth cytochrome, sometimes called complexes. 12 00:02:08,000 --> 00:02:16,000 This is the last stage in how the ATPase pumps out ATP. 13 00:02:16,000 --> 00:02:25,000 The energy molecule our mitochondria are making, a brief refresh on our mitochondria. 14 00:02:25,000 --> 00:02:30,000 You know it as the so-called powerhouse of the cell. 15 00:02:30,000 --> 00:02:40,000 It takes energy from the environment. It could be food, but certainly light and oxygen. 16 00:02:40,000 --> 00:02:50,000 Remember the four red light chromophores and the VDR vitamin D receptors, which are UV light detectors. 17 00:02:50,000 --> 00:02:54,000 Light is electromagnetic. 18 00:02:54,000 --> 00:03:00,000 Remember the iron sulfur clusters and iron being magnetic. 19 00:03:00,000 --> 00:03:10,000 Oxygen is paramagnetic, meaning it collects two particles or molecules and so forth that are magnetic. 20 00:03:10,000 --> 00:03:17,000 It hitches a ride on iron or anything magnetic. 21 00:03:17,000 --> 00:03:24,000 Now you can understand iron and hebo-globin too. 22 00:03:24,000 --> 00:03:27,000 This is transferring energy. 23 00:03:27,000 --> 00:03:31,000 Last thing on the mitochondria for now. 24 00:03:31,000 --> 00:03:34,000 The ATPase has an FO head. 25 00:03:34,000 --> 00:03:46,000 This is a quantum rotary engine and it spins upwards to 9000 spins per second, which pumps out the ATP. 26 00:03:46,000 --> 00:03:52,000 Okay, enough recap. We need to get on with today's topic. 27 00:03:52,000 --> 00:04:05,000 Quantum biology is a discipline explaining biological phenomena that uses various features such as coherence, tunneling, entanglement. 28 00:04:05,000 --> 00:04:14,000 It suggests biological systems evolved using these mechanisms over billions of years. 29 00:04:14,000 --> 00:04:19,000 Photosynthesis is the easy go-to. 30 00:04:19,000 --> 00:04:25,000 Enzyme catalyst is another. We just talked about enzymes. 31 00:04:25,000 --> 00:04:29,000 So also think protein synthesis. 32 00:04:29,000 --> 00:04:36,000 Think Paschal Jordan, Niles Bohr, Erwin Schrodinger. 33 00:04:36,000 --> 00:04:42,000 These theories explain how the environment influences molecules. 34 00:04:42,000 --> 00:04:47,000 I should say atoms and molecules. 35 00:04:47,000 --> 00:04:50,000 This is everything. 36 00:04:50,000 --> 00:05:00,000 This is the whole purpose and the whole explanation for how autism magically shows up in human evolution. 37 00:05:00,000 --> 00:05:06,000 Transferring energy from the environment through our biology. 38 00:05:06,000 --> 00:05:13,000 We are no different than the trees outside, except we eat food. 39 00:05:13,000 --> 00:05:21,000 Whereby we are supplementing the earth's nutrients because we are not connected to the earth. 40 00:05:21,000 --> 00:05:25,000 We don't grow upwards from the ground. 41 00:05:25,000 --> 00:05:30,000 So therefore we must eat the food. 42 00:05:30,000 --> 00:05:33,000 Quantum coherence. 43 00:05:33,000 --> 00:05:49,000 Okay. Coherence is the role whereby light initiated reactions in photosynthetic organisms such as mammals, trees, fruit bushes, and so forth. 44 00:05:49,000 --> 00:05:53,000 Anything that receives light. 45 00:05:53,000 --> 00:05:57,000 Integrate energy transfer. 46 00:05:57,000 --> 00:06:04,000 It moves states. Quantum states. Coherent states. 47 00:06:04,000 --> 00:06:08,000 Particles like electrons and photons. 48 00:06:08,000 --> 00:06:15,000 Atoms exhibit multiple states such as superposition. 49 00:06:15,000 --> 00:06:20,000 The coherence maintains a relationship. 50 00:06:20,000 --> 00:06:26,000 If one take away, life on earth is driven by light. 51 00:06:26,000 --> 00:06:30,000 Light gives life. 52 00:06:30,000 --> 00:06:38,000 Connected to the ground or on the ground or moving about on the ground. 53 00:06:38,000 --> 00:06:43,000 We are talking about the atoms creating molecules. 54 00:06:43,000 --> 00:06:48,000 The fundamental building blocks of matter. 55 00:06:48,000 --> 00:06:56,000 Remember Einstein. Light provides energy after it hits matter. 56 00:06:56,000 --> 00:07:02,000 The reason here is these mechanisms underpin our biology. 57 00:07:02,000 --> 00:07:12,000 Light, water, oxygen, and so forth are seasonal and change with the environment. 58 00:07:12,000 --> 00:07:19,000 Today humans are indoor creatures in large part. 59 00:07:19,000 --> 00:07:23,000 Not all communities, but most. 60 00:07:23,000 --> 00:07:28,000 Follow that trend. Zoom out. Give yourself a chance here to see this. 61 00:07:28,000 --> 00:07:30,000 Look at the Amish. 62 00:07:30,000 --> 00:07:33,000 Look at the communities around the equator. 63 00:07:33,000 --> 00:07:38,000 Look at countries that are not fully modernized. 64 00:07:38,000 --> 00:07:41,000 Now let's compare the rates. 65 00:07:41,000 --> 00:07:45,000 Ok. Quantum thermodynamics. 66 00:07:45,000 --> 00:07:47,000 This is a good one. 67 00:07:47,000 --> 00:07:49,000 Phinomenon won a Nobel. 68 00:07:49,000 --> 00:07:55,000 But I guess to be accurate, so did Einstein, Bohr, and Schrodinger. 69 00:07:55,000 --> 00:08:01,000 The absorption of the photon, meaning matter. 70 00:08:01,000 --> 00:08:08,000 For humans, our skin is the largest organ and is very powerful. 71 00:08:08,000 --> 00:08:14,000 It's a solar panel. Remember Milano sites and Carantino sites. 72 00:08:14,000 --> 00:08:22,000 Remember melanin is much, much more than skin, eye, and hair color. 73 00:08:22,000 --> 00:08:30,000 Light hits matter and transfers the energy to the electron. 74 00:08:30,000 --> 00:08:34,000 This excites it to a higher state. 75 00:08:34,000 --> 00:08:39,000 Remember the recent mentions of states. 76 00:08:39,000 --> 00:08:45,000 There are rules to this mechanism. Of course, physics loves rules. 77 00:08:45,000 --> 00:08:49,000 In large part, it's probability. 78 00:08:49,000 --> 00:08:58,000 The matter increases energy. In other words, does its business and emits a photon? 79 00:08:58,000 --> 00:09:07,000 Bio-photon. Sunlight has 20,000 to 30,000 lux in the morning sun and its sunset. 80 00:09:07,000 --> 00:09:16,000 100,000 or even upwards to maybe 120,000 lux during midday. 81 00:09:16,000 --> 00:09:19,000 Remember, this can change seasonally. 82 00:09:19,000 --> 00:09:30,000 Also, data are strong on autism rates based on, one, the season, the season of the birth, 83 00:09:30,000 --> 00:09:37,000 and two, the latitude. These are undeniable. 84 00:09:37,000 --> 00:09:42,000 With everything that we know, such as the GI, autism and GI, 85 00:09:42,000 --> 00:09:50,000 and everything we now know from the placenta and the wombs relationship, from Dr. Hannah Stevens, 86 00:09:50,000 --> 00:09:57,000 everything we know about the underdeveloped cells and problems with protein synthesis 87 00:09:57,000 --> 00:10:02,000 and problems with energy in the autistic phenotype. 88 00:10:02,000 --> 00:10:08,000 All of this is known and not really disputed. It's not controversial. 89 00:10:08,000 --> 00:10:20,000 Yet, we cannot fully grasp this concept, physical law concept, about how humans evolved, how mammals evolved. 90 00:10:20,000 --> 00:10:28,000 Yet, if we hear somebody say, well, a lot of our neurotransmitters and proteins are synthesized through the skin 91 00:10:28,000 --> 00:10:33,000 and gut via those malano sites and carantino sites, 92 00:10:33,000 --> 00:10:42,000 and when you hear that 95% of our serotonin is in our GI tract, this isn't really complicated. 93 00:10:42,000 --> 00:10:51,000 That's agreed. Yet, whenever we apply a cause, if this is abnormal, then we can complicate things. 94 00:10:51,000 --> 00:10:53,000 We love that. 95 00:10:53,000 --> 00:10:58,000 In quantum thermodynamics, there's also scattering. 96 00:10:58,000 --> 00:11:06,000 The blue sky is the easy example and also refraction and reflection. 97 00:11:06,000 --> 00:11:15,000 Most importantly, the new know or you ought to know electrons drives mitochondria. 98 00:11:15,000 --> 00:11:27,000 Mitochondria is where cells get their energy, which is where and how we develop in simple terms. 99 00:11:27,000 --> 00:11:33,000 Cells develop trillions and trillions of cells. 100 00:11:33,000 --> 00:11:39,000 Where do you think humans get our energy? From food? 101 00:11:39,000 --> 00:11:45,000 Modern humans, especially under our centralized paradigm, probably think food. 102 00:11:45,000 --> 00:11:50,000 This is incorrect in large part. This is false. 103 00:11:50,000 --> 00:11:53,000 I did not say we don't need food. 104 00:11:53,000 --> 00:12:01,000 Remember the lux from the sun? Remember, light has wavelengths. 105 00:12:01,000 --> 00:12:11,000 Now, artificial light, same mechanism, photon, energy, matter, and so forth. 106 00:12:11,000 --> 00:12:21,000 Artificial light are isolated wavelengths and much lower lux. 107 00:12:21,000 --> 00:12:32,000 Living rooms, offices, school classrooms, and so forth, roughly 500 to 800 lux. 108 00:12:32,000 --> 00:12:36,000 You can see, it's a big difference. 109 00:12:36,000 --> 00:12:46,000 So, from tens of thousands, up to 100,000, to a couple of hundred. 110 00:12:46,000 --> 00:12:53,000 Do you get that? Not only are we missing the full spectrum of light from UV to those infrareds. 111 00:12:53,000 --> 00:13:03,000 280 nanometer light to 3100 nanometer light. We're just getting isolated in the visual spectrum, mostly. 112 00:13:03,000 --> 00:13:06,000 Modern light is blue light. 113 00:13:06,000 --> 00:13:09,000 I'm hoping to connect this. 114 00:13:09,000 --> 00:13:15,000 Hoping that this is understood. And now, you can also understand obesity. 115 00:13:15,000 --> 00:13:23,000 Do you get why? Big Harma is cleaning house with GLP-1s? 116 00:13:23,000 --> 00:13:32,000 They're just replacing the sunlight, the energy lost from the sunlight with this vastly expensive new drug, this new technology, 117 00:13:32,000 --> 00:13:38,000 with unknown side effects, unknown longitudinal studies. 118 00:13:38,000 --> 00:13:42,000 But people will flock to this because it's easy, it's quick. 119 00:13:42,000 --> 00:13:52,000 It's something that they don't have to be uncomfortable with, because they don't have to remove themselves from this new, modern, and comfortable environment. 120 00:13:52,000 --> 00:13:56,000 We'll see. We'll see the connections here. 121 00:13:56,000 --> 00:14:02,000 All of this, all of this is just a massive loss of energy. 122 00:14:02,000 --> 00:14:11,000 This stuff is so simple. It is so simple if you go here. 123 00:14:11,000 --> 00:14:19,000 Autism is a lack of energy and development. 124 00:14:19,000 --> 00:14:31,000 It's hard for people to accept. We want to hear something we can make sense of and think, that must be it, or that is it. 125 00:14:31,000 --> 00:14:40,000 We don't like that critical thinking, that those underlying feelings that are uncomfortable when we don't know something. 126 00:14:40,000 --> 00:14:44,000 This is human nature. This is in all forms of learning. 127 00:14:44,000 --> 00:14:56,000 Every time you learn, every time you attempt new things or you want to change, the central nervous system just wants to respond. 128 00:14:56,000 --> 00:15:00,000 It doesn't like those insults. 129 00:15:00,000 --> 00:15:16,000 We love when something confirms what we are, what we think, our beliefs, and we hate when something offends those, offends us, offends our capacity to think and understand. 130 00:15:16,000 --> 00:15:21,000 It is just human nature. 131 00:15:21,000 --> 00:15:33,000 The evolution of artificial light changes, follows the rates of modern chronic health implications. 132 00:15:33,000 --> 00:15:39,000 Light hits matter and energy happens. 133 00:15:39,000 --> 00:15:49,000 Electrons in biology. This is the title of the paper. Let's talk how the energy happens. 134 00:15:49,000 --> 00:15:54,000 Water, more cytochrome c-oxidase. 135 00:15:54,000 --> 00:16:08,000 Water forms coherent domains. There are links to three podcast episodes that are fantastic in an explanation about water. 136 00:16:08,000 --> 00:16:14,000 Water has interactions with electromagnetic fields. 137 00:16:14,000 --> 00:16:25,000 This organizes molecules. This influences cellular functions, growth, and death. 138 00:16:25,000 --> 00:16:32,000 Health can be defined as how much water your mitochondria are producing. 139 00:16:32,000 --> 00:16:39,000 And as we age, we naturally decrease water production, roughly 10% a decade. 140 00:16:39,000 --> 00:16:52,000 However, in diseases and pathology, inflammation and so forth, water is even reduced further than that, more than that. 141 00:16:52,000 --> 00:16:59,000 Semiconductions, melanin and water are powerful and necessary. 142 00:16:59,000 --> 00:17:08,000 Melanin receives the light. The business of sales are happening based on the brief mechanisms from earlier. 143 00:17:08,000 --> 00:17:14,000 Increasing electrons is the goal. 144 00:17:14,000 --> 00:17:25,000 DHA. Look up the nomenclature of DHA. I'm not attempting to say this. 145 00:17:25,000 --> 00:17:31,000 DHA is a method for increasing electron efficiency. 146 00:17:31,000 --> 00:17:41,000 DHA interacts with cellular functions and has a huge role in the cell membrane. 147 00:17:41,000 --> 00:17:49,000 The DHA has a long chain and double bonds. Long chains just describe the carbons. 148 00:17:49,000 --> 00:17:55,000 Not important for us, important, but not for us, for the takeaway. 149 00:17:55,000 --> 00:18:02,000 The bonds describes the methyl and it helps reduce its melting point. 150 00:18:02,000 --> 00:18:16,000 This allows it to support the cell, the synapses, and the plasticity, how we change and develop, how we adapt to the environment. 151 00:18:16,000 --> 00:18:29,000 One thing to mention, DHA has never changed or said differently, has never evolved into something different. There's no need to. 152 00:18:29,000 --> 00:18:35,000 DHA provides the core of photoreceptors. 153 00:18:35,000 --> 00:18:42,000 Photoreceptors. Remember, we are solar powered creatures. 154 00:18:42,000 --> 00:18:58,000 And these photoreceptors, which we have many, we have many photoreceptors, they convert energy of photons that in turn stimulate our nervous systems, 155 00:18:58,000 --> 00:19:17,000 and in large part, the brain. DHA are fascinating and are in cephalopods, fish, amphibians, reptiles, birds, mammals, including humans. 156 00:19:17,000 --> 00:19:36,000 A quick sidebar here. During the roles of oxytocin and basopressin on the autistic phenotype during that episode, I made a comment that it appears that oxytocin has very dynamic and diverse roles that it has. 157 00:19:36,000 --> 00:19:47,000 A very simple peptide, nine proteins. It shows that oxytocin's role in human development is vast. 158 00:19:47,000 --> 00:19:54,000 Maybe the reason why we are completely upright and has given us more complex life. 159 00:19:54,000 --> 00:20:09,000 DHA is also in this category. DHA is likely another component or molecule, I should say, of what makes humans so complex and developed. 160 00:20:09,000 --> 00:20:27,000 Something very interesting is the history, the phylogeny of oxytocin and DHA go back millions of years, certainly in much less organisms, simple organisms. 161 00:20:27,000 --> 00:20:37,000 This has a long history. And they were also seen, DHA and oxytocin, in similar species, similar types of creatures. 162 00:20:37,000 --> 00:20:42,000 So we've evolved using these molecules. 163 00:20:42,000 --> 00:20:54,000 Vasotocin into oxytocin and basopressin. However, DHA remains DHA. 164 00:20:54,000 --> 00:21:03,000 It is the primary, acyl component of photoreceptor, synaptic and neural signaling membranes. 165 00:21:03,000 --> 00:21:12,000 The goal here is quantum transfer and communication of pi electrons. Pi electrons, huge in the double bonds. 166 00:21:12,000 --> 00:21:22,000 You can see these on the stick molecules, the kind of ball and stick drawings that you can see of atoms and molecules and such. 167 00:21:22,000 --> 00:21:34,000 This dynamic row suggests it is DHA that dictates DNA. We should go here, we should understand this. 168 00:21:34,000 --> 00:21:46,000 It is about environmental signals processed through our biology. And for that reason, mostly the central paradigm is wrong. 169 00:21:46,000 --> 00:21:56,000 If you hear a discussion or if we discuss, this is true for foliage, things growing in the environment, in the woods, in our yard and so forth. 170 00:21:56,000 --> 00:22:01,000 This all makes perfect sense for us. We can understand that. 171 00:22:01,000 --> 00:22:12,000 But if we think about, we are created through environmental signals the same way we have evolved. And we're here on Earth. 172 00:22:12,000 --> 00:22:20,000 We have life on Earth because of these environmental signals such as the light, the sunlight, and the Earth's electromagnetic field. 173 00:22:20,000 --> 00:22:27,000 Humans' resonance. We can make sense of that. This is all accepted. 174 00:22:27,000 --> 00:22:36,000 But as soon as we talk about humans evolved like this, and this is how we are created, it's very complicated. We'd love to complicate that. 175 00:22:36,000 --> 00:22:52,000 It's hard for us to go here. I want to read a quote, a very significant and I just love this quote from someone who teaches quantum physics, quantum biology, better than anybody, in my opinion. 176 00:22:52,000 --> 00:23:00,000 He says, I realize that all biochemistry is the bridesmaid to physics. 177 00:23:00,000 --> 00:23:07,000 I then realize that physics are how the business of cells gets completed. 178 00:23:07,000 --> 00:23:17,000 Light is the biophysical levers that control substrate level biochemistry and cells. 179 00:23:17,000 --> 00:23:25,000 That's Dr. Jack Frues. Very worthy of checking out his Patreon. 180 00:23:25,000 --> 00:23:34,000 I'm not a tie to that, but I will tell you. It's very valuable for health, information, and longevity. 181 00:23:34,000 --> 00:23:42,000 Cells and cell tissue. DHA is crucial for this process. 182 00:23:42,000 --> 00:23:53,000 The fatty acid and lipids are huge. Neurotransmission, receptor functions, and the plasticity of the synapsis. 183 00:23:53,000 --> 00:24:01,000 This is huge in autism, which is not controversial. There are many data reporting this. 184 00:24:01,000 --> 00:24:07,000 Many people accepting this as a problem in autism. 185 00:24:07,000 --> 00:24:16,000 Developing, learning, memory, and evolving as organisms. 186 00:24:16,000 --> 00:24:31,000 We interact and change. We interact with each other, with the environment, within ourselves, especially autism. 187 00:24:31,000 --> 00:24:36,000 We interact with the environment. 188 00:24:36,000 --> 00:24:45,000 The data are impressive for omega-3 in pregnancy and for the autistic post birth. 189 00:24:45,000 --> 00:24:51,000 Remember Dr. Hannah Stevens and the role of the placenta and womb. 190 00:24:51,000 --> 00:25:05,000 This is so important. This is the origins of autism. The beginning, upstream process of what is autism. 191 00:25:05,000 --> 00:25:21,000 DHA is vital for inflammation, endothelial processes, cell signaling, immune responses, cell cycle regulation, 192 00:25:21,000 --> 00:25:28,000 and in autism cleaning up the cells or pruning is a problem. 193 00:25:28,000 --> 00:25:37,000 The synaptic plasticity, the so-called fluidity for neuro membranes, very important. 194 00:25:37,000 --> 00:25:51,000 A previous discussed neurotropin, BDNF, brain derived, neutropic factor from episode 5 is crucial for development. 195 00:25:51,000 --> 00:26:01,000 This is abnormal in autism. It is abnormal in any types of abnormal development. 196 00:26:01,000 --> 00:26:10,000 Intellectual disability, development delay, any problems with learning, learning disabilities, so forth. 197 00:26:10,000 --> 00:26:14,000 These are all similar downstream phenotypes. 198 00:26:14,000 --> 00:26:22,000 The whole weather is always this, autism and XYZ, especially for younger autistics. 199 00:26:22,000 --> 00:26:29,000 There is full of these underdeveloped chronic health implications. 200 00:26:29,000 --> 00:26:41,000 The allergies and the eczema, this praxia, repetitive restricted behaviors, the stemming, the stereotyping motor movements. 201 00:26:41,000 --> 00:26:51,000 Once the organism develops to a certain epoch, a certain stage of one's life, all of these things start showing up very similarly. 202 00:26:51,000 --> 00:26:54,000 There are all these downstream implications here. 203 00:26:54,000 --> 00:27:06,000 My problem is, the autism research, they don't go far enough upstream to really funnel out all of these similarities to get to the true root cause. 204 00:27:06,000 --> 00:27:11,000 And that's my goal. That's the sole goal now of the podcast. 205 00:27:11,000 --> 00:27:20,000 Let's go upstream to the very beginnings of when is autism developing and where. 206 00:27:20,000 --> 00:27:28,000 Maybe the placenta-womb interaction, maybe it's the embryogenesis or the third trimester even. 207 00:27:28,000 --> 00:27:33,000 There's so much data on autism in the womb. 208 00:27:33,000 --> 00:27:42,000 And things got real complicated with the DSM classifications and the public perception of autism. 209 00:27:42,000 --> 00:27:50,000 Let's define autism. I ask you to go look up the definition of autism or autistic. 210 00:27:50,000 --> 00:27:53,000 This is what autism is. 211 00:27:53,000 --> 00:27:58,000 Now we just lump several different conditions into autism. 212 00:27:58,000 --> 00:28:07,000 Autism is just social withdrawal. No lack or regard for the environment, the surroundings. 213 00:28:07,000 --> 00:28:12,000 We are just very in tune in our inner world. 214 00:28:12,000 --> 00:28:26,000 Right? You know it's sponsored from schizophrenia, very lower levels, without the auditory and visual abnormal hallucinations or the psychotic delusional features. 215 00:28:26,000 --> 00:28:31,000 We are just inside of our own little inner world. 216 00:28:31,000 --> 00:28:40,000 The outside world is very complicated. It's very unpredictable and very uninteresting, quite frankly. 217 00:28:40,000 --> 00:28:47,000 Autism in relationships, human relationships, are across the board challenging. 218 00:28:47,000 --> 00:29:02,000 However, relationships to subjects, topics and objects are well defined, well observed from the 1930s and still present and still. 219 00:29:02,000 --> 00:29:07,000 The core feature of what is autism? 220 00:29:07,000 --> 00:29:11,000 Criteria B3, know that. 221 00:29:11,000 --> 00:29:18,000 If you don't know the symptoms, the criteria, then how do you think you understand autism? 222 00:29:18,000 --> 00:29:21,000 What is your source of information? 223 00:29:21,000 --> 00:29:29,000 My takeaways are, DHA is a fiber optic for electrons. 224 00:29:29,000 --> 00:29:37,000 You might know the role and the eyes. The eyes are more than just vision. 225 00:29:37,000 --> 00:29:41,000 The eyes are the interstate to the brain. 226 00:29:41,000 --> 00:29:45,000 We've talked about the differences between myelin as well. 227 00:29:45,000 --> 00:29:51,000 Myelin is like driving on a highway or Audubon or interstate. 228 00:29:51,000 --> 00:29:57,000 Unmyelinated is more of a, like a gravel road, tough terrain. 229 00:29:57,000 --> 00:30:01,000 Things aren't moving across it as efficiently. 230 00:30:01,000 --> 00:30:05,000 This is why DHA is huge here in the eye. 231 00:30:05,000 --> 00:30:16,000 The central retinal pathway must be, arguably, the most efficient area in our biology for signaling. 232 00:30:16,000 --> 00:30:22,000 If not, everything downstream is off, delayed. 233 00:30:22,000 --> 00:30:24,000 Remember melanin? 234 00:30:24,000 --> 00:30:28,000 Melanin is applied here too. This is why. 235 00:30:28,000 --> 00:30:31,000 The semiconductors. 236 00:30:31,000 --> 00:30:40,000 DHA conveys the information of the environment to the molecules in our biology. 237 00:30:40,000 --> 00:30:47,000 This is why proteins are doing when synthesized. 238 00:30:47,000 --> 00:30:57,000 In addition to the central retinal pathway, which covers the brain, DHA are huge in liver and gut. 239 00:30:57,000 --> 00:31:12,000 Interesting now that Dr. Stevens informed us about the placenta and the womb and how that develops the central nervous system of the embryo, or said differently, of the child. 240 00:31:12,000 --> 00:31:21,000 Now we can also begin to understand the roles of pre-pregnancy, getting into the pregnancy, and the environment of the mother. 241 00:31:21,000 --> 00:31:36,000 The environment of modern humans, especially the mother, is going to be the most crucial, the most likely source to improve the rates of autism. 242 00:31:36,000 --> 00:31:42,000 If we don't go here, we won't do anything with the rates. 243 00:31:42,000 --> 00:31:44,000 OK. 244 00:31:44,000 --> 00:31:47,000 NFKB. 245 00:31:47,000 --> 00:31:57,000 Nuclear factor. Kappa light. Chain enhancer of activated B cells. 246 00:31:57,000 --> 00:32:07,000 Light. Not light from earlier, but light in the terms of weight or density. 247 00:32:07,000 --> 00:32:17,000 NFKB is a transcription factor highly involved in inflammatory responses. 248 00:32:17,000 --> 00:32:30,000 Interesting. In autism samples, in the orbital frontal cortex, a prefrontal area involved in socialness and cognitive processes. 249 00:32:30,000 --> 00:32:39,000 We have calculators. Sets of rules used in learning and memory and evaluating current states. 250 00:32:39,000 --> 00:32:48,000 Risk rewards. Reward prediction error. Aversion prediction error. Conflict monitoring and so forth. 251 00:32:48,000 --> 00:32:59,000 We have all of these internal calculators. We have these and they are constantly running calculations and updating in real time. 252 00:32:59,000 --> 00:33:07,000 The OFC, the orbital frontal cortex, provides data for these processes. 253 00:33:07,000 --> 00:33:24,000 The episode with Dr. Stevens intended to discuss the dorsal striatum because this area receives the inputs from the prefrontal and the sensory motor and the midbrain areas used in these calculations. 254 00:33:24,000 --> 00:33:30,000 Remember adaptive responses and our metabolic bank account. 255 00:33:30,000 --> 00:33:42,000 Do I have enough resources to cover this task in real time, in physical form or in thoughts and planning? 256 00:33:42,000 --> 00:33:52,000 NFKB coherence and signaling by which it helps regulate inflammation and immune. 257 00:33:52,000 --> 00:34:04,000 In autism, NFKB related genes and non-coding RNAs and peripheral blood is shown in autism. 258 00:34:04,000 --> 00:34:14,000 A region of interest is if NFKB implicates symbiochemistry changes. 259 00:34:14,000 --> 00:34:20,000 The explanation from Dr. Stevens covered this better than I. 260 00:34:20,000 --> 00:34:27,000 I will end on this. It has several interesting roles with cell survival. 261 00:34:27,000 --> 00:34:29,000 Proliferation. 262 00:34:29,000 --> 00:34:31,000 Apoptosis. 263 00:34:31,000 --> 00:34:33,000 The cytoplasm. 264 00:34:33,000 --> 00:34:37,000 And cytokines, which are big in cell adhesion. 265 00:34:37,000 --> 00:34:39,000 Migration. 266 00:34:39,000 --> 00:34:43,000 Helping cells adapt and in development. 267 00:34:43,000 --> 00:34:59,000 A role in the central nervous system. Remember the conversation with Dr. Eric Weiss talked about the cytokines in this umbilical cord stem cell and regenerative medicine approach that they use. 268 00:34:59,000 --> 00:35:05,000 Cytokines is a huge part of this process. 269 00:35:05,000 --> 00:35:12,000 If you are listening to the podcast or listening to the episode, please feel free to leave a review or rating. 270 00:35:12,000 --> 00:35:21,000 In podcasting, reviews, ratings and downloads are huge and I very much appreciate your feedback. 271 00:35:21,000 --> 00:35:31,000 You can contact me on X where we can have discussions about autism at RPS 47586. 272 00:35:31,000 --> 00:35:47,000 You can check out the hop link for links to all of the shows and contact information, including email. Info.FromTheSpectrum.com. 273 00:35:47,000 --> 00:36:02,000 Thank you for listening to From The Spectrum podcast.