1 00:00:00,000 --> 00:00:10,840 Welcome to From the Spectrum Podcast. This is a podcast about autism. It is my goal to 2 00:00:10,840 --> 00:00:20,880 explain what is autism. I plan to use a mixture of scientific literature, personal experience, 3 00:00:20,880 --> 00:00:29,200 and opinion. With opinion, I will explain why. I show the way I do and give examples. 4 00:00:29,200 --> 00:00:36,040 I will provide links to various references for each episode. For each episode, we will 5 00:00:36,040 --> 00:00:47,160 discuss various aspects of autism. For today's episode, we will cover mitochondria. The 6 00:00:47,160 --> 00:00:56,920 mitochondria, which is plural, mitochondrion, is singular, or vast for living organisms. 7 00:00:56,920 --> 00:01:07,000 Often, mitochondria are considered the powerhouse of the cell. We've covered light, water, and 8 00:01:07,000 --> 00:01:17,040 magnetism as the central foundation of life, including human life. Today, we will have 9 00:01:17,040 --> 00:01:25,720 more understanding of these three critical components in our living organism. 10 00:01:25,720 --> 00:01:34,960 Today's episode is an introduction because mitochondria is very critical in this discussion 11 00:01:34,960 --> 00:01:43,280 and we cannot cover everything. We will prepare for a future episode featuring an expert, an 12 00:01:43,280 --> 00:01:53,680 MD, and a PhD in biophysics to explain the roles of autism and mitochondria. If you 13 00:01:53,680 --> 00:02:01,840 go to PubMed and type in just a broad search of mitochondria into the PubMed's search 14 00:02:01,840 --> 00:02:09,840 engine, you will see recently, over the last one to two decades, the number of publishings 15 00:02:09,840 --> 00:02:18,360 on mitochondria has a vast and sharp increase. The understanding of mitochondria is becoming 16 00:02:18,360 --> 00:02:27,480 more apparent. The roles in human biology and health versus senescence and death is becoming 17 00:02:27,480 --> 00:02:38,040 more recognized. What we will talk about are not topics that help our life. They are topics 18 00:02:38,040 --> 00:02:47,960 in our biology that gives us life. Most cells have mitochondria. All cells accept red blood 19 00:02:47,960 --> 00:02:55,720 cells and two types of cells from the autism and gastrointestinal episodes. Bacteria and 20 00:02:55,720 --> 00:03:04,240 archaea. Red blood cells use deuterium water and you will find out mitochondria is a role 21 00:03:04,240 --> 00:03:13,800 of producing water. Mitochondria needs a different type of water than blood or hemoglobin. Red 22 00:03:13,800 --> 00:03:21,600 blood cells use hemoglobin which allows optimal oxygen transportation. You will soon find 23 00:03:21,600 --> 00:03:31,160 out oxygen and the mitochondria is delicate. Bacteria and archaea, their absence of mitochondria 24 00:03:31,160 --> 00:03:40,720 is because those are prokaryotic cells. Prokaryotic cells are less complex and then eukaryotic 25 00:03:40,720 --> 00:03:50,560 cells are more complex. All the organelles within a cell nucleus including mitochondria, 26 00:03:50,560 --> 00:03:57,360 it's believed that everything in the cell nucleus was once independent or separate from 27 00:03:57,360 --> 00:04:05,520 each other. And the collection of these different organelles coming together in the cell nucleus 28 00:04:05,520 --> 00:04:15,600 gives rise to more complex living organisms to more complex life. In the prokaryotic bacteria 29 00:04:15,600 --> 00:04:26,360 and archaea it shares a cytochrome c-oxidase with eukaryotic mitochondria cells. In eukaryotic 30 00:04:26,360 --> 00:04:35,480 cells that more complex cell nucleus and mitochondria, cytochrome c-oxidase is the fourth of five 31 00:04:35,480 --> 00:04:45,160 cytochromes. We've talked about humans use photosynthesis. This is here and crucial parts 32 00:04:45,160 --> 00:04:53,760 of hemoglobin and mitochondria. Hemoglobin and chlorophyll are nearly the same except 33 00:04:53,760 --> 00:05:03,920 hemoglobin uses iron. Chlorophyll uses magnesium. Iron will be a critical part for today. Iron 34 00:05:03,920 --> 00:05:13,120 in both blood and the mitochondria have magnetic properties. This is a heme sometimes called 35 00:05:13,120 --> 00:05:22,560 hemo protein. These are molecules containing iron which binds to oxygen. Remember the magnetic 36 00:05:22,560 --> 00:05:33,600 part of the story. Hems store and transport globins. Hence hemo-globin conserves energy. 37 00:05:33,600 --> 00:05:41,480 Another area for today photosynthesis and respiratory cytochromes which will be most 38 00:05:41,480 --> 00:05:52,080 of our conversation is also a catalyst meaning starting or accelerating and hemes since changes 39 00:05:52,080 --> 00:06:00,800 in redox states. So more involvement with oxygen. So a brief recap the elements that 40 00:06:00,800 --> 00:06:12,360 we will discuss. It's energy, oxygen, water, proteins, ions both negative ions which are 41 00:06:12,360 --> 00:06:22,320 electrons and positive ions which are protons and the electromagnetic fields. Light is a 42 00:06:22,320 --> 00:06:31,960 driving force. Light or a lack of light depending on the cellular state and function. Meaning 43 00:06:31,960 --> 00:06:39,200 if the cell is active and functioning and healthy it's receiving optimal light, optimal 44 00:06:39,200 --> 00:06:50,320 electromagnetic fields. If the cell is lacking energy or cell death even it is neglected 45 00:06:50,320 --> 00:06:59,080 from these energy properties. The powerhouse of the cell, the mitochondria and cellular 46 00:06:59,080 --> 00:07:06,920 respiration. There are three components that we will spend most of the time on. These are 47 00:07:06,920 --> 00:07:19,040 all energy producing paths. One is glycolysis. Two is citric acid cycle or sometimes called 48 00:07:19,040 --> 00:07:29,920 TCA cycle or even Crab cycle. This is briefly mentioned in cause of autism episode. Hans 49 00:07:29,920 --> 00:07:38,600 Krebs the Nobel winner this was mentioned around minute 16 of the cause of autism episode. 50 00:07:38,600 --> 00:07:46,480 Also Albert St. George's another Nobel winner has critical roles here with that the protein 51 00:07:46,480 --> 00:07:51,880 discovering the semiconductor. Essentially what we're talking about with all of those 52 00:07:51,880 --> 00:07:59,920 ingredients mentioned earlier those elements we are creating semiconductor properties. 53 00:07:59,920 --> 00:08:09,080 And the third component of the cellular respiration is oxidative phosphorylation. This will include 54 00:08:09,080 --> 00:08:17,160 the electron transport chain also briefly mentioned in previous episodes. The ATPase 55 00:08:17,160 --> 00:08:26,640 and chymiosmosis or the movement of ions across membranes and across the gradient. First is 56 00:08:26,640 --> 00:08:36,520 glycolysis. This is glucose metabolism that creates two molecules of pyruvate. You probably 57 00:08:36,520 --> 00:08:44,840 know glucose is released for energy. This is where it takes action. This is the cells 58 00:08:44,840 --> 00:08:56,200 cytoplasm. The goal is to break down glucose and use a transporter to enter the mitochondria. 59 00:08:56,200 --> 00:09:03,160 Glucose binds to insulin and there is a straw like feature for a transporter which allows 60 00:09:03,160 --> 00:09:16,600 the glucose to enter. Pyruvate kinase isoform M2 or PKM2 is labeled metabolic budgeting 61 00:09:16,600 --> 00:09:31,040 system. This is a factor in autistic biology. Pyruvate has ATP and NADH outputs. ATP is 62 00:09:31,040 --> 00:09:38,800 adenosine triphosphate which transfers energy. This is what we are trying to achieve in 63 00:09:38,800 --> 00:09:50,160 cellular respiration. The NADH carries electrons. With oxygen and pyruvate, acetyl coenzyme 64 00:09:50,160 --> 00:10:01,240 A sometimes shown as aceto coa is created and the citric acid the TCA cycle needs it. 65 00:10:01,240 --> 00:10:11,200 It needs it. The citric acid cycle. This occurs in the mitochondria matrix and is central 66 00:10:11,200 --> 00:10:19,760 driver for cellular respiration. The cycle is used to release stored energy from oxidation 67 00:10:19,760 --> 00:10:29,240 of acetyl coenzyme A which is derived from carbohydrates and fats or protein into carbon 68 00:10:29,240 --> 00:10:44,080 dioxide and chemical energy of ATP. It also produces NADH and FADH2. These are coenzymes. 69 00:10:44,080 --> 00:10:59,520 FADH2 is a cofactor. These are required for metabolism. FADH2 and NADH are catabolism 70 00:10:59,520 --> 00:11:05,520 which breaks down complex molecules which we've discussed into simpler forms. Simpler 71 00:11:05,520 --> 00:11:15,320 molecules, then mechanisms can use these simple forms for energy. This is life. This is upstream 72 00:11:15,320 --> 00:11:28,640 metabolism. NADH and FADH2, the electron carriers are crucial. We will cover all five of the 73 00:11:28,640 --> 00:11:38,840 cytochromes in the electron transport chain and the ATPase momentarily. Both glycolysis 74 00:11:38,840 --> 00:11:50,160 and the citric acid cycle uses NAD plus breaking it down to NADH. Glycolysis and the citric 75 00:11:50,160 --> 00:11:58,320 acid cycle just many components moving parts. They are like conveyor belts feeding into 76 00:11:58,320 --> 00:12:07,720 the cytochromes in the electron transport chain. Now oxidative phosphorylation. This 77 00:12:07,720 --> 00:12:19,200 is where the magic happens but without glycolysis and without the citric acid oxidative phosphorylation 78 00:12:19,200 --> 00:12:28,680 suffers. This is the final stage of cellular respiration. This includes the electron transport 79 00:12:28,680 --> 00:12:42,560 chain and ATP synthase and chymiosmosis. ATP generated in one of these two metabolic pathways 80 00:12:42,560 --> 00:12:51,560 glycolysis and or oxidative phosphorylation. We've discussed just briefly the electron 81 00:12:51,560 --> 00:13:00,560 transport chain and the cytochromes involved. Cytochromes are chromophores. In other words 82 00:13:00,560 --> 00:13:11,080 these are a unique type of protein. This translates into color and carriers of chromophores. I'll 83 00:13:11,080 --> 00:13:21,760 say again translates into color and carriers of. It means they absorb specific wavelengths 84 00:13:21,760 --> 00:13:30,320 of light and you know the position on the cause of autism and all of the chronic diseases 85 00:13:30,320 --> 00:13:39,680 that are just downstream of essentially everything we're talking about today. Today's conversation 86 00:13:39,680 --> 00:13:47,600 will take us essentially as far upstream in human functioning, human metabolism and biological 87 00:13:47,600 --> 00:14:01,120 sequencing as we can go. Cytochrome 1 or sometimes called ubiquinone. The products of glycolysis 88 00:14:01,120 --> 00:14:14,000 are oxidized here transferring two electrons from NADH to FMN or Flavin. You might have 89 00:14:14,000 --> 00:14:22,400 heard of Flavin products such as green tea or supplemental form. The electrons are then 90 00:14:22,400 --> 00:14:30,840 used in CoQ10. You might have even heard about this or seen it on your supplement aisle in 91 00:14:30,840 --> 00:14:42,160 your supplement store or grocery store. CoQ10 is a coenzyme and these are lipophilic and 92 00:14:42,160 --> 00:14:51,160 it's reduced form ubiquinol also in cytochrome 1 or 8 iron sulfur clusters. So here we are 93 00:14:51,160 --> 00:15:01,080 with the iron. Remember the magnetic field and hydrogen. Hydrogen and electrons are produced. 94 00:15:01,080 --> 00:15:09,680 They are broken down from these separate processes and produced here. Then we move to cytochrome 95 00:15:09,680 --> 00:15:20,000 2. This uses electrons from succunate in the citric acid cycle and we are passing electrons 96 00:15:20,000 --> 00:15:32,280 down the path using iron sulfur clusters and CoQ10 to cytochrome 3. Succunate is a catalyst 97 00:15:32,280 --> 00:15:41,640 of the oxidative process being fed to cytochrome 3 which will turn these products into water. 98 00:15:41,640 --> 00:15:50,840 Essentially we are making water and ATP. You might have heard of ROS, reactive oxidative 99 00:15:50,840 --> 00:15:58,800 stress. This is cytochrome 3, this process that we are working up to will take oxygen 100 00:15:58,800 --> 00:16:07,280 and create water. The whole purpose of breaking these molecules down into smaller molecules 101 00:16:07,280 --> 00:16:16,560 is this. Cytochrome 3 is called cytochrome C reductase. Heme proteins and iron sulfur 102 00:16:16,560 --> 00:16:25,880 clusters are used. Heme groups alternate between ferrous and ferric. Proton gradients begin 103 00:16:25,880 --> 00:16:34,680 to add up a two step Q cycle is used to move into cytochrome C oxidase. This is a transfer 104 00:16:34,680 --> 00:16:42,080 in breaking down of processes or elements because cytochrome C can only accept a single 105 00:16:42,080 --> 00:16:52,000 electron at one time. So this occurs in two steps. The cytochrome 3 also releases the 106 00:16:52,000 --> 00:16:59,720 four protons. Just a special note about the hydrogen 2. Hydrogen is building up and is 107 00:16:59,720 --> 00:17:07,240 necessary. So we are processing different elements, different molecules I should say, 108 00:17:07,240 --> 00:17:13,800 into the matrix and the inter membrane. And this brings us to maybe the most underrated 109 00:17:13,800 --> 00:17:23,720 or not appreciated process in the whole mitochondria. And that's the creation of water. Now I ran 110 00:17:23,720 --> 00:17:30,520 through the first processes to get to this point fairly quickly and I did not highlight 111 00:17:30,520 --> 00:17:37,280 the elements or the molecules that's being produced, the amount of them and essentially 112 00:17:37,280 --> 00:17:46,400 I didn't mention the reasons. However, we are here for these reasons right now. One 113 00:17:46,400 --> 00:17:53,760 is to get to cytochrome C oxidase as fast as possible and two there are obviously lots 114 00:17:53,760 --> 00:17:59,680 of molecules and atomic processes going on here. I want to be mindful of the podcast. 115 00:17:59,680 --> 00:18:06,680 I want to be mindful of the information regarding autism because you might think we haven't 116 00:18:06,680 --> 00:18:16,680 even talked about autism. However, I would hold off on that thought. So cytochrome C 117 00:18:16,680 --> 00:18:23,560 oxidase. Remember this has four red light chromophores from the cause of autism episode 118 00:18:23,560 --> 00:18:34,560 from 620 to 860 nanometer light. This process creates water. The electrons we've been transferring 119 00:18:34,560 --> 00:18:43,880 and creating and the oxygen that's being created into water. Light. Remember the light story 120 00:18:43,880 --> 00:18:55,040 the whole purpose of this topic. Light charge separates water. Water equals H plus the hydrogen 121 00:18:55,040 --> 00:19:06,960 and oxygen and two electrons. So how does light create more water? We've established light 122 00:19:06,960 --> 00:19:19,200 is electromagnetic. Understand it? We've established autism is a light story. Low electrons, low 123 00:19:19,200 --> 00:19:28,680 melanin is a modern human phenomena. Also we've established isolated light, especially blue 124 00:19:28,680 --> 00:19:38,440 light, dehydrates cells. Well this is it. This is where the damage is in the lipid rafts 125 00:19:38,440 --> 00:19:47,200 of the process of exchanging these molecules from smaller molecules and transferring them 126 00:19:47,200 --> 00:19:53,880 down the process. And here is a big takeaway because we've now explained the creation of 127 00:19:53,880 --> 00:20:03,280 water and the mitochondria. Not all water is equal. It changes its physics based on 128 00:20:03,280 --> 00:20:13,000 the environment it's in. Mitochondria is the reverse process of photosynthesis. Instead 129 00:20:13,000 --> 00:20:21,800 of producing oxygen and sugar like the photosynthesis of a plant, the mitochondria produces carbon 130 00:20:21,800 --> 00:20:33,160 dioxide and water. This water is an electromagnetic capacitor. It is a battery. An old car battery 131 00:20:33,160 --> 00:20:43,640 uses this process. A key note here is water is a dipole, meaning the electrons has negative 132 00:20:43,640 --> 00:20:52,480 charges and protons as positive charges. You know that we are creating electrons and 133 00:20:52,480 --> 00:21:01,280 protons which are crucial ingredients to this process. Now you can understand that the 134 00:21:01,280 --> 00:21:10,640 iron and some oxygen and water, the magnetic properties of these elements are crucial. 135 00:21:10,640 --> 00:21:18,840 In addition, water is a paradoxity, meaning it is very responsible for the clock timing 136 00:21:18,840 --> 00:21:27,880 mechanisms occurring within this mitochondrial matrix. Our clock timed mechanisms are crucial 137 00:21:27,880 --> 00:21:35,320 and that begins in the SCN. We've discussed the SCN. How and when are all of these elements 138 00:21:35,320 --> 00:21:44,160 and these biological ingredients functioning are critical. And another note about the water 139 00:21:44,160 --> 00:21:51,840 here in the mitochondria and just water in general. Water is very heat tolerant and we 140 00:21:51,840 --> 00:21:58,560 want our mitochondria to be this heat and dissipative structure. We want massive amounts 141 00:21:58,560 --> 00:22:08,800 of energy and production here. Mother Nature chose water. It uses water accurately here. 142 00:22:08,800 --> 00:22:18,360 It's by design. Water with heat tolerant, it can endure so much and be very reliable. 143 00:22:18,360 --> 00:22:25,240 You can also remember melanin from the cause of autism episode. How melanin is also very 144 00:22:25,240 --> 00:22:33,840 enduring and can absorb all frequencies of light. The light which is, you know, a vast 145 00:22:33,840 --> 00:22:40,680 component of this story and also within melanin being that neuroprotective. We've discussed 146 00:22:40,680 --> 00:22:50,000 that neuroprotective role here. It keeps this process functioning. Different light has different 147 00:22:50,000 --> 00:22:58,400 effects on water, has different effects on our electron transport chain. Light has different 148 00:22:58,400 --> 00:23:07,240 effects on the glucose getting to the cytoplasm released from the organs. Light, remember the 149 00:23:07,240 --> 00:23:15,000 pom-C story. Remember now that we've discussed glycolysis and remember the previous conversations 150 00:23:15,000 --> 00:23:25,200 about pom-C. Pro, opioid, malano, cortin and how cortisol and alpha malano site stimulating 151 00:23:25,200 --> 00:23:32,760 hormones, the melanin found throughout the body on the surface and deep inside of us 152 00:23:32,760 --> 00:23:41,640 and tissues and organs are implicated from the light source. Melanin here is a different 153 00:23:41,640 --> 00:23:50,920 story. Melanin and light takes the water and is the semi-conductive properties. It uses 154 00:23:50,920 --> 00:24:01,320 this in a dissipative structure. In other words, it is a method of creating more energy 155 00:24:01,320 --> 00:24:12,680 and remember the pom-C and how insulin is generated from here, from CLIP, CLIP. If glucose 156 00:24:12,680 --> 00:24:22,640 is affected and insulin sensitivity is infected, the process getting to the mitochondria for 157 00:24:22,640 --> 00:24:31,960 glycolysis are implicated. Remember the blue light, our modern light now, about 440 to 480 158 00:24:31,960 --> 00:24:41,360 nanometer light. That's modern LED and tech light. Most, nearly all of the light exposure 159 00:24:41,360 --> 00:24:50,080 humans get now falls within this range and this dehydrates cells. Now maybe you can understand 160 00:24:50,080 --> 00:24:59,240 why. We've talked about cytochrome c-oxidase. These dehydrated cells, the implications to 161 00:24:59,240 --> 00:25:07,600 water production from cytochrome c-oxidase will cause hetero plasma which is a decrease 162 00:25:07,600 --> 00:25:19,120 of water and this is where disease manifests in the body. This is lower dissipative ability. 163 00:25:19,120 --> 00:25:29,560 Meaning as we age, water production drops. Okay, so there's an understanding that humans 164 00:25:29,560 --> 00:25:38,520 are roughly 70% water or so. I don't know what the paradigm suggests but at birth we 165 00:25:38,520 --> 00:25:47,320 are about 80% water and that is shown to be we decrease water about 10% every decade. 166 00:25:47,320 --> 00:25:54,600 Now Doug Wallace is a good source of this and so is Jack Cruz. As we age and reduce our 167 00:25:54,600 --> 00:26:03,160 water production we need to increase the electrons getting to the mitochondria level to produce 168 00:26:03,160 --> 00:26:12,360 more water. We have to supplement our aging and the decrease of electrons with proper, 169 00:26:12,360 --> 00:26:21,240 that's key here, proper electromagnetic fields. The melanin story which is frequently discussed 170 00:26:21,240 --> 00:26:27,040 or mentioned at least throughout the several episodes of the podcast. This is underrated 171 00:26:27,040 --> 00:26:35,160 here too. Melanin charge separates water like no other element or molecule in the human 172 00:26:35,160 --> 00:26:43,200 body and lastly on the cytochrome c-oxidase for now. I mentioned there are four red light 173 00:26:43,200 --> 00:26:52,280 chromophores and this one protein. Why are there four red light chromophores and cytochrome 174 00:26:52,280 --> 00:27:06,240 c-oxidase? Why and how are humans using this? Especially with our modern light. Based on 175 00:27:06,240 --> 00:27:13,520 some information from a decentralized neuro surgeon, he has over 10,000 surgeries in his 176 00:27:13,520 --> 00:27:24,000 career. He suggests that the red light chromophores and cytochrome c-oxidase where water is produced 177 00:27:24,000 --> 00:27:35,000 links the entire mitochondrial matrix including the protein metabolism, the TCA cycle glycolysis 178 00:27:35,000 --> 00:27:44,680 and the red light chromophores. Red light is what spins the FO head and ATP synthase 179 00:27:44,680 --> 00:27:54,160 which is the fifth and final cytochrome. Now you can understand maybe you can kind of attach 180 00:27:54,160 --> 00:28:03,160 the rates of autism follows almost identically with the sources of light. One, the timing 181 00:28:03,160 --> 00:28:09,680 of artificial light that we are under beginning back in the 1930s with an incandescent type 182 00:28:09,680 --> 00:28:18,640 all the way up through the LED production and the shift to LED and now technology, technology 183 00:28:18,640 --> 00:28:27,280 follows essentially every single human being especially around the ages of 6 to 8. I guess 184 00:28:27,280 --> 00:28:34,160 maybe closer to 8 to 10 people are getting cell phones now and autism is a generational 185 00:28:34,160 --> 00:28:44,320 issue. With this light exposure people's water production is decreasing and our melanin 186 00:28:44,320 --> 00:28:54,800 inside of us is decreasing. This is why light and melanin are the key candidates for the 187 00:28:54,800 --> 00:29:06,720 cause of autism. The light exposure follows identically the rates of autism. And second 188 00:29:06,720 --> 00:29:15,880 thing we need to consider is that power source the sun spectra at 280 to 3100 nanometers our 189 00:29:15,880 --> 00:29:24,760 biology is missing those components. Okay so we make water and now let's get to the 190 00:29:24,760 --> 00:29:35,480 cytochrome 5 which is ATP synthase ATPase. The hydrogen charge separated in cytochrome 191 00:29:35,480 --> 00:29:46,360 c-oxidase to produce water that charge separation or protons. The protons are H plus ions, 192 00:29:46,360 --> 00:29:56,720 positive charged ions this is hydrogen. On the ATPase is an FO head. FO is a proton 193 00:29:56,720 --> 00:30:07,720 channel. In ATPase the head spins 9000 to 12000 times per second and every 3 or 4 spins 194 00:30:07,720 --> 00:30:16,680 creates 1 ATP. Okay so here's some more magnetic properties here the FO head with that spinning 195 00:30:16,680 --> 00:30:25,560 that rapid spinning creates a magnetic field. This is a quantum nano rotary engine that 196 00:30:25,560 --> 00:30:34,840 works on red light. Where are modern humans getting red light? Remember the rant just 197 00:30:34,840 --> 00:30:43,720 a couple of minutes ago the sun is 43 to 47 percent red but it requires humans to spend 198 00:30:43,720 --> 00:30:54,000 time under it and remember our photosynthesis. Okay so why the red light? You remember from 199 00:30:54,000 --> 00:31:00,400 the cause of autism episode and probably some other episodes that red light penetrates the 200 00:31:00,400 --> 00:31:09,480 body deeper than any other specter of light including bones. Red light penetrates bones 201 00:31:09,480 --> 00:31:17,520 and remember the antioxidant effect here with the with the cancer treatment. Red light 202 00:31:17,520 --> 00:31:28,000 is very powerful against carcinoma and tumors and that is shown in many many articles in 203 00:31:28,000 --> 00:31:35,520 PubMed. In addition what people might fail to understand is our mitochondria is where 204 00:31:35,520 --> 00:31:47,320 95 percent of our melatonin is generated. Melatonin is a light hormone that works at night the 205 00:31:47,320 --> 00:31:56,920 absence of light and this is our number one antioxidant. So this is all from longer wavelengths 206 00:31:56,920 --> 00:32:04,280 of light on one side of the sun spectra but also you can kind of come together here and 207 00:32:04,280 --> 00:32:12,160 understand that this is more and more of the light story light water magnetism with the 208 00:32:12,160 --> 00:32:19,560 light story it doesn't just include those longer wavelengths of light vitamin D receptors 209 00:32:19,560 --> 00:32:28,520 are involved. Okay so more sun this is UVB remember the biosynthesis discussed in autism 210 00:32:28,520 --> 00:32:38,240 and gastrointestinal problems it goes the biosynthesis it goes pre vitamin D2 and D3 211 00:32:38,240 --> 00:32:48,400 is 216 nanometer light. Tachysterol the next process is 280 nanometer light and then pro 212 00:32:48,400 --> 00:32:55,920 vitamin D3 is 293 nanometer light and then we get to vitamin D the full synthesis of 213 00:32:55,920 --> 00:33:04,840 vitamin D is 312 nanometer light. The VDR blocks electron transport chain but that's 214 00:33:04,840 --> 00:33:11,760 okay here that just means we don't need to eat as much when we are outside if you've 215 00:33:11,760 --> 00:33:16,560 ever noticed that maybe you don't eat as much whenever you're outside in the sun that's 216 00:33:16,560 --> 00:33:25,960 because that glucose used during glycolysis is kind of supplemented here with the VDR 217 00:33:25,960 --> 00:33:34,920 structures. Our photobiomodulation and the mitochondria as dissipative structures in 218 00:33:34,920 --> 00:33:43,360 the sense of nonlinear optics used in human biology. Healthy human biology is built in 219 00:33:43,360 --> 00:33:52,000 mechanism to create energy and we do this we've discussed pom-C and that release of 220 00:33:52,000 --> 00:34:01,480 cortisol and that coincides with glucose this is what it's all about we evolved under 221 00:34:01,480 --> 00:34:11,600 the sun and this natural electromagnetic fields we've taken the electrons from the 222 00:34:11,600 --> 00:34:22,800 sun and used it for energy production inside of us inside the so-called powerhouse of the 223 00:34:22,800 --> 00:34:33,680 cell. Modern humans and all of our chronic diseases are electron deficient. Most ATP 224 00:34:33,680 --> 00:34:43,400 from the cell happens from sun on cytochrome c-oxidase and ATPase from infrared and UV 225 00:34:43,400 --> 00:34:55,040 on VDR receptors. Now you can begin to understand the obesity epidemic. Now you can understand 226 00:34:55,040 --> 00:35:03,120 type 2 diabetes. Remember how we've mentioned the insulin sensitivity and the release of 227 00:35:03,120 --> 00:35:12,640 glucose and metabolizing all of this energy production. Obesity is a cause of people 228 00:35:12,640 --> 00:35:20,880 losing energy to the environment. It's not all cases of calories in versus calories 229 00:35:20,880 --> 00:35:28,920 out food intake and the lack of movement and exercise. Now the lack of movement and exercise 230 00:35:28,920 --> 00:35:34,920 could be explained here too because people don't have energy because they're not they're 231 00:35:34,920 --> 00:35:42,960 not producing water. For the autism story now you can even understand the roles of autism 232 00:35:42,960 --> 00:35:54,800 and metabolism and autism and inflammation. Cells and our biology are not adapted to our 233 00:35:54,800 --> 00:36:05,280 new environments. You understanding this? We are adapting but these are not healthy adaptations. 234 00:36:05,280 --> 00:36:14,920 Autism is neuroplasticity to our light and energy change. Research and people's beliefs 235 00:36:14,920 --> 00:36:25,440 are in the wrong place. There are all of these autism and XYZ. I am tired of autism and XYZ. 236 00:36:25,440 --> 00:36:35,240 I am tired quite frankly of autism and allergies or autism and eczema or autism and gastrointestinal 237 00:36:35,240 --> 00:36:43,720 problems. Autism and dyspraxia. Autism has a higher rate of higher chance of Alzheimer's 238 00:36:43,720 --> 00:36:50,360 and Parkinson's. On that note you ought to be able to understand a little bit better 239 00:36:50,360 --> 00:36:58,840 now the role of light and these rapid cognitive declines that we are now seeing. And I've 240 00:36:58,840 --> 00:37:07,720 said Alzheimer's is a reverse process of autism. Hopefully you can kind of make sense 241 00:37:07,720 --> 00:37:17,040 of this. Now as we discussed the cell metabolism, the way that the cell is functioning, the 242 00:37:17,040 --> 00:37:25,520 powerhouse with autism you know the problems exist on the cellular level and the synaptic 243 00:37:25,520 --> 00:37:35,800 level. The cellular level here is explained. This is why cells aren't developing. Also 244 00:37:35,800 --> 00:37:45,600 to note that remember our genes response to the environment. In other words our environmental 245 00:37:45,600 --> 00:37:55,280 signals informs the genes how to respond. The environmental signals are the cues for 246 00:37:55,280 --> 00:38:04,960 DNA sequencing and guess what? In the cell nucleus the organelle of DNA sequencing and 247 00:38:04,960 --> 00:38:13,320 mitochondria are closely related. Genetic studies receives much attention. There's a 248 00:38:13,320 --> 00:38:23,360 lot of money thrown at GWAS studies. This genome sequencing and genome-wide understanding 249 00:38:23,360 --> 00:38:31,280 and with autism there are over 100 so-called risk genes. Now what this is saying is there 250 00:38:31,280 --> 00:38:38,840 are many complicated factors here. There are many genes involved that might cause autism 251 00:38:38,840 --> 00:38:46,260 or might not cause autism. This because you have duplications or deletions, copy number 252 00:38:46,260 --> 00:38:54,280 variants and so forth of this gene. Well it might mean autism. In my opinion autism 253 00:38:54,280 --> 00:39:00,880 research because of the amount of funding and attention thrown at it. But the genes 254 00:39:00,880 --> 00:39:08,040 has reached a dead end and at the dead end it takes bulldozers and just kind of barrels 255 00:39:08,040 --> 00:39:16,120 through trying to find some sort of hidden treasure. And this is all wrong. The genes 256 00:39:16,120 --> 00:39:26,160 of humans the DNA is vastly different than the mitochondria genes. Mitochondria has 257 00:39:26,160 --> 00:39:36,080 its own DNA. There are only 37 total for mitochondria. Now this is a huge difference and with everything 258 00:39:36,080 --> 00:39:42,720 we've just discussed you ought to understand that huh mitochondria is very important to 259 00:39:42,720 --> 00:39:54,800 the cell health, to our life. Not only is it just 37 genes but the cytochromes, the powerhouses, 260 00:39:54,800 --> 00:40:01,880 the source of energy processing these electrons and protons and creating water and creating 261 00:40:01,880 --> 00:40:13,320 ATP. There are only 13 DNA responsible of the mitochondria for this function. This meaning 262 00:40:13,320 --> 00:40:24,560 13 genes that we can study to really find out some more information about. What is autism? 263 00:40:24,560 --> 00:40:29,400 If you are listening to the podcast or listening to the episode please feel free to leave a 264 00:40:29,400 --> 00:40:37,200 review or rating. In podcasting reviews, ratings and downloads are crucial and I very much 265 00:40:37,200 --> 00:40:47,880 appreciate your feedback. You can contact me on X at RPS 47586. We can have discussions 266 00:40:47,880 --> 00:40:56,680 about autism and especially the cause of autism. These atomic molecular levels. You can email 267 00:40:56,680 --> 00:41:17,960 me info.fromthespectrum.com. Thank you for listening to From the Spectrum podcast.