WEBVTT 00:00:00.000 --> 00:00:02.779 Prepare to have your health questions answered 00:00:02.779 --> 00:00:06.740 here on Safe, Effective, Natural Solutions with 00:00:06.740 --> 00:00:10.119 Dr. Todd Binkley, owner of Binkley Healing Center 00:00:10.119 --> 00:00:15.180 in downtown Ventura. Now, here's Dr. Todd. Good 00:00:15.180 --> 00:00:17.280 afternoon. I'm Dr. Todd Bankley, board certified 00:00:17.280 --> 00:00:19.600 doctor of non -force chiropractic and clinical 00:00:19.600 --> 00:00:22.120 nutritionist. Thanks for tuning in today. We're 00:00:22.120 --> 00:00:24.739 going to talk about a continuation of three in 00:00:24.739 --> 00:00:27.160 a row now, a series on Alzheimer's and dementia. 00:00:27.339 --> 00:00:29.519 I got more than the usual number of questions 00:00:29.519 --> 00:00:31.500 after last week's show and the week before that, 00:00:31.559 --> 00:00:34.320 but especially after last week's about creatine, 00:00:34.420 --> 00:00:36.740 how to use it, where to get it, et cetera. I'm 00:00:36.740 --> 00:00:38.320 going to talk a little bit more about where to 00:00:38.320 --> 00:00:40.920 get more information about creatine and its effects 00:00:40.920 --> 00:00:42.659 on dementia here in a little bit. But before 00:00:42.659 --> 00:00:44.899 I do that, as always, when I start any discussion 00:00:44.899 --> 00:00:48.000 about alzheimer's and dementia the focus is always 00:00:48.000 --> 00:00:50.479 has to be on prevention and sometimes people 00:00:50.479 --> 00:00:52.320 get tired of me talking about that because most 00:00:52.320 --> 00:00:55.219 people want a solution well certainly a lot of 00:00:55.219 --> 00:00:58.880 people uh who knows what most of us or many of 00:00:58.880 --> 00:01:01.259 us at least probably most of us tell me if i'm 00:01:01.259 --> 00:01:04.260 wrong know someone who has suffered or still 00:01:04.260 --> 00:01:06.900 is suffering the devastating effects of dementia 00:01:06.900 --> 00:01:10.920 and you know it's it's a it's a kind of inevitable 00:01:10.920 --> 00:01:13.799 for some people But it is not inevitable for 00:01:13.799 --> 00:01:16.519 everyone. And the difference between that is 00:01:16.519 --> 00:01:18.620 often genetic. We're going to talk about the 00:01:18.620 --> 00:01:23.409 APOE gene again. But for many of us, one of the 00:01:23.409 --> 00:01:25.569 reasons, the main reason probably that it's so 00:01:25.569 --> 00:01:28.909 common is because the same process that causes 00:01:28.909 --> 00:01:30.849 heart disease, one of the number one diseases 00:01:30.849 --> 00:01:34.629 in America, the number one and two causes of 00:01:34.629 --> 00:01:37.269 death are always heart disease and cancer. And 00:01:37.269 --> 00:01:39.329 they kind of trade places once in a while. But 00:01:39.329 --> 00:01:41.549 all of the same processes that result in loss 00:01:41.549 --> 00:01:44.689 of circulation, hardening of the arteries, formation 00:01:44.689 --> 00:01:47.129 of plaques that can cause heart attacks and strokes, 00:01:47.269 --> 00:01:49.489 all of these effects. on your cardiovascular 00:01:49.489 --> 00:01:52.750 system, which are mostly preventable, mostly 00:01:52.750 --> 00:01:55.189 the result of lifestyle, mostly the result of 00:01:55.189 --> 00:01:57.250 not eating enough good food and too much bad 00:01:57.250 --> 00:02:00.189 food that causes inflammation, that drives the 00:02:00.189 --> 00:02:03.010 formation of tears in the lining of your vessels 00:02:03.010 --> 00:02:05.650 that then start the process of plaque formation. 00:02:06.390 --> 00:02:09.389 That inflammatory diet and stressful lifestyles 00:02:09.389 --> 00:02:12.909 causes and at least dramatically accelerates 00:02:12.909 --> 00:02:15.990 the progress of cardiovascular disease. All those 00:02:15.990 --> 00:02:20.039 same processes, dramatically increase your risk 00:02:20.039 --> 00:02:22.800 of dementia. The same process that causes a lack 00:02:22.800 --> 00:02:25.479 of circulation and little clots to form and blockages 00:02:25.479 --> 00:02:30.139 of microvessels in the brain causes loss of brain 00:02:30.139 --> 00:02:33.080 tissue, which causes ultimately the symptoms, 00:02:33.219 --> 00:02:37.960 memory loss and other symptoms. So prevention 00:02:37.960 --> 00:02:40.680 is key. And here's a really interesting study 00:02:40.680 --> 00:02:44.639 that just came out in May of 2025 to bring that 00:02:44.639 --> 00:02:47.539 home. The title is Risk Factors for Alzheimer's 00:02:47.539 --> 00:02:50.240 Disease and Cognitive Function Before Middle 00:02:50.240 --> 00:02:53.180 Age. and a United States representative population. 00:02:53.360 --> 00:02:55.340 So this is published in Lancet Regional Health. 00:02:55.520 --> 00:02:58.180 This is kind of an American version of the British 00:02:58.180 --> 00:03:00.979 Journal. So Lancet Regional Health America is 00:03:00.979 --> 00:03:03.819 May 2025. Study on young Americans published 00:03:03.819 --> 00:03:07.020 in a British Journal. Key factors for Alzheimer's 00:03:07.020 --> 00:03:10.400 are linked to cognitive function as early as 00:03:10.400 --> 00:03:15.219 ages 24 to 44. So that's a broad range, but 24 00:03:15.219 --> 00:03:18.650 to 44. Wow, most people don't notice the symptoms 00:03:18.650 --> 00:03:21.849 until much later. And if you do, and it's called 00:03:21.849 --> 00:03:25.349 early onset dementia. So this is highlighting, 00:03:25.569 --> 00:03:29.590 really highlighting and bringing home why people 00:03:29.590 --> 00:03:32.349 need to focus on prevention in the U .S. and 00:03:32.349 --> 00:03:36.250 elsewhere. So data from this U .S. National Longitudinal 00:03:36.250 --> 00:03:39.270 Study of Adolescent Adult Health. That's the 00:03:39.270 --> 00:03:41.509 original study that they analyzed. 15 ,000 participants 00:03:41.509 --> 00:03:44.659 enrolled in 95. They were enrolled in the years 00:03:44.659 --> 00:03:48.520 1994 to 1995 when they were in junior high and 00:03:48.520 --> 00:03:51.099 high school, grades 7 through 12. And then they 00:03:51.099 --> 00:03:54.819 were followed through 2018. So 15 ,000 young 00:03:54.819 --> 00:03:59.819 Americans began this study in 1994 and 1995 when 00:03:59.819 --> 00:04:01.900 they were in seventh grade and it followed through 00:04:01.900 --> 00:04:04.530 graduation from high school. which was in the 00:04:04.530 --> 00:04:08.830 year 2018 on average. And again, ages 10 through 00:04:08.830 --> 00:04:13.389 18 were followed up at ages 24 through 34, and 00:04:13.389 --> 00:04:18.170 again from ages 34 to 44. So there was multiple 00:04:18.170 --> 00:04:20.569 overlapping studies. That's why there's no one 00:04:20.569 --> 00:04:22.769 starting date and ending date, but they were 00:04:22.769 --> 00:04:25.910 averaging. participants from a number of years 00:04:25.910 --> 00:04:29.730 and, you know, collating the information from 00:04:29.730 --> 00:04:32.089 that. So the important thing is this is the first 00:04:32.089 --> 00:04:35.189 study to systematically examine Alzheimer's disease 00:04:35.189 --> 00:04:38.750 risk factors in a large sample of generally healthy 00:04:38.750 --> 00:04:42.360 individuals. aged 24 to 44 in the U .S., and 00:04:42.360 --> 00:04:45.199 they targeted this range specifically to identify 00:04:45.199 --> 00:04:49.759 the earliest associations between known key Alzheimer's 00:04:49.759 --> 00:04:53.259 disease risk factors and cognitive function patterns 00:04:53.259 --> 00:04:56.879 before midlife. And so the findings of this study 00:04:56.879 --> 00:04:59.379 suggest that risk profiles for Alzheimer's emerge 00:04:59.379 --> 00:05:03.300 long before middle age, revealing early manifestations 00:05:03.300 --> 00:05:05.720 of cognitive patterns that may predict the decline 00:05:05.720 --> 00:05:08.779 typically observed. In older populations. So 00:05:08.779 --> 00:05:11.259 what does that mean? The diabetes risk factors 00:05:11.259 --> 00:05:14.920 included cardiovascular risk factors, amyloid, 00:05:14.920 --> 00:05:17.600 what they call the ATN biomarkers, which are 00:05:17.600 --> 00:05:22.339 biomarkers for amyloid, tau proteins, and neurodegeneration. 00:05:22.379 --> 00:05:24.560 So these are tests that have been around for 00:05:24.560 --> 00:05:27.939 a while. Under a microscope, damaged brain tissue, 00:05:28.079 --> 00:05:31.339 when they do an autopsy on people with Alzheimer's, 00:05:31.379 --> 00:05:33.259 they have consistently shown that people with 00:05:33.259 --> 00:05:36.389 Alzheimer's have a huge buildup. proteins in 00:05:36.389 --> 00:05:38.230 the brain that are really scar tissue in the 00:05:38.230 --> 00:05:40.850 brain. They're the result of a chronic inflammatory 00:05:40.850 --> 00:05:45.649 process that has gone in overdrive, produced 00:05:45.649 --> 00:05:47.550 way too much. So it's a normal process is the 00:05:47.550 --> 00:05:51.389 point. There's normally amyloid proteins and 00:05:51.389 --> 00:05:54.629 tau proteins in the brain, but it gets accelerated. 00:05:55.439 --> 00:05:57.699 And the acceleration of the formation of scar 00:05:57.699 --> 00:05:59.899 tissue anywhere in the body is almost always 00:05:59.899 --> 00:06:02.319 the result of some kind of chronic inflammatory 00:06:02.319 --> 00:06:05.579 process. And that's important because chronic 00:06:05.579 --> 00:06:09.220 inflammatory processes are largely preventable. 00:06:09.259 --> 00:06:12.139 You can eat food that is less inflammatory. You 00:06:12.139 --> 00:06:15.240 can take nutrients that help control inflammation. 00:06:15.420 --> 00:06:17.939 You can reduce your stress that helps control 00:06:17.939 --> 00:06:20.939 inflammation. Long before you end up with a permanent 00:06:20.939 --> 00:06:23.740 irreversible degenerative condition. and long 00:06:23.740 --> 00:06:25.959 before you need to take anti -inflammatory drugs 00:06:25.959 --> 00:06:28.279 like corticosteroids, etc. So anyway, the risk 00:06:28.279 --> 00:06:30.540 factors for Alzheimer's disease that they're 00:06:30.540 --> 00:06:33.379 looking at in this study are cardiovascular risk 00:06:33.379 --> 00:06:35.620 factors, standard blood tests that measure your 00:06:35.620 --> 00:06:37.579 cardiovascular risk because they know that is 00:06:37.579 --> 00:06:40.800 directly associated with your level of disease 00:06:40.800 --> 00:06:43.879 risk for dementia, and then the amyloid proteins, 00:06:44.180 --> 00:06:47.319 tau proteins, and other neurodegeneration markers, 00:06:47.459 --> 00:06:50.040 so these are known as the ATN biomarkers, as 00:06:50.040 --> 00:06:52.819 well as immune. measures of your immune system 00:06:52.819 --> 00:06:54.980 function. For those of you who want to know more 00:06:54.980 --> 00:06:56.720 specific details and aren't going to rush out 00:06:56.720 --> 00:06:58.680 and look up this study online, in addition to 00:06:58.680 --> 00:07:01.839 age, education, sex, systolic blood pressure, 00:07:01.899 --> 00:07:04.759 and body mass index, they measured cholesterol, 00:07:05.060 --> 00:07:08.500 physical activity, the APOE gene, which we're 00:07:08.500 --> 00:07:11.259 going to talk about more, and also total tau 00:07:11.259 --> 00:07:15.089 and neurofilament light. which are the talent 00:07:15.089 --> 00:07:17.129 amyloid proteins I mentioned before, high sensitivity 00:07:17.129 --> 00:07:20.910 CRP, which is a measure of systemic inflammation 00:07:20.910 --> 00:07:24.470 anywhere in the body, as well as immune system 00:07:24.470 --> 00:07:27.810 related interleukins, which are the things that 00:07:27.810 --> 00:07:29.589 show up in your bloodstream when you have a lot 00:07:29.589 --> 00:07:32.009 of inflammation happening. So they measured IL 00:07:32.009 --> 00:07:36.149 -beta, IL -6, IL -8, and IL -10. Those are all 00:07:36.149 --> 00:07:38.310 interleukins that are associated with inflammatory 00:07:38.310 --> 00:07:41.730 reactions produced by the immune system, as well 00:07:41.730 --> 00:07:45.220 as tumor necrosis factor. Alpha, another one 00:07:45.220 --> 00:07:48.680 of those markers for inflammation. And they were 00:07:48.680 --> 00:07:50.699 surprised to find that these were elevated in 00:07:50.699 --> 00:07:54.620 younger populations. In addition to these biomarkers, 00:07:54.620 --> 00:07:57.259 home interviewers conducted cognitive assessments 00:07:57.259 --> 00:08:01.459 among all the participants of things like word 00:08:01.459 --> 00:08:04.790 recall. Delayed word recall and backward digit 00:08:04.790 --> 00:08:07.230 span, counting backwards. They were read a 15 00:08:07.230 --> 00:08:09.629 -word list for word recall and asked to recall 00:08:09.629 --> 00:08:12.329 as many of the 15 words as possible. And then 00:08:12.329 --> 00:08:15.029 their cognitive scores were standardized and 00:08:15.029 --> 00:08:18.370 analyzed to associate with higher memory function. 00:08:18.920 --> 00:08:22.019 The study goes on to list many, many pages of 00:08:22.019 --> 00:08:24.699 really specific technical data that is of interest 00:08:24.699 --> 00:08:27.819 to neurologists with sentences like this. Among 00:08:27.819 --> 00:08:30.759 adults aged 24 to 34, each one point increase 00:08:30.759 --> 00:08:34.840 in the CAIDE score was associated with a 0 .03 00:08:34.840 --> 00:08:37.259 standard deviation decrease in the average backward 00:08:37.259 --> 00:08:40.980 digit span score adjusted for covariates. So 00:08:40.980 --> 00:08:42.639 if you thought that sounded like dense reading, 00:08:42.799 --> 00:08:44.779 good, because that's why I'm not going to read 00:08:44.779 --> 00:08:47.210 any more of that. or refer to any more of that. 00:08:47.289 --> 00:08:48.990 So it's important that they're doing all that 00:08:48.990 --> 00:08:51.049 because it's specific and detailed and reproducible, 00:08:51.210 --> 00:08:53.110 and that is the things that they measure when 00:08:53.110 --> 00:08:55.210 you do studies like these. But the easy way to 00:08:55.210 --> 00:08:58.570 think about it is that their findings show that 00:08:58.570 --> 00:09:00.970 Alzheimer's disease risk factors, measurable 00:09:00.970 --> 00:09:04.090 disease risk factors, which have been known about 00:09:04.090 --> 00:09:07.870 for a long time, are measurable in early adulthood 00:09:07.870 --> 00:09:12.389 in the U .S. population over two to four decades. 00:09:13.070 --> 00:09:15.370 Earlier than previously thought, the several 00:09:15.370 --> 00:09:18.350 key risk factors for Alzheimer's disease associated 00:09:18.350 --> 00:09:21.490 with standard measures of cognition in 24 to 00:09:21.490 --> 00:09:26.149 44 -year -olds show that these things are already 00:09:26.149 --> 00:09:28.490 being expressed and measurable with standard 00:09:28.490 --> 00:09:33.649 tests as early as age 25. 24 and very common, 00:09:33.789 --> 00:09:36.149 relatively much more common than previously thought 00:09:36.149 --> 00:09:40.529 in 34 and especially 44 -year -olds. So the signs 00:09:40.529 --> 00:09:42.710 of cognitive decline, the signs of damage to 00:09:42.710 --> 00:09:45.389 the brain, the signs of measurable loss in function 00:09:45.389 --> 00:09:48.950 are showing up in U .S. adults in their 30s. 00:09:49.289 --> 00:09:53.970 That's so and so important because anyone can 00:09:53.970 --> 00:09:55.809 do the things that I'm talking about all the 00:09:55.809 --> 00:09:57.690 time to prevent that, to dramatically reduce 00:09:57.690 --> 00:10:00.149 your risk of basically just taking care of your 00:10:00.149 --> 00:10:02.250 health. Eating good food, actually the things 00:10:02.250 --> 00:10:03.809 you hear about all the time, maybe you get tired 00:10:03.809 --> 00:10:06.370 of hearing about, this is proving that it will 00:10:06.370 --> 00:10:08.409 actually work, dramatically reduce your risk 00:10:08.409 --> 00:10:10.830 of dementia if you just take care of your health 00:10:10.830 --> 00:10:13.149 and take care of your heart. Exercise, eat good 00:10:13.149 --> 00:10:16.799 food. reduce stress, and get tested for the things 00:10:16.799 --> 00:10:18.379 that you can measure, like these cardiovascular 00:10:18.379 --> 00:10:20.620 risk factors that they measured in these 20 and 00:10:20.620 --> 00:10:22.500 30, or anybody can measure those right now, standard 00:10:22.500 --> 00:10:25.019 blood tests. Unfortunately, most doctors don't 00:10:25.019 --> 00:10:27.879 do those tests routinely. You have to spend a 00:10:27.879 --> 00:10:29.659 little money out of pocket to order some of those 00:10:29.659 --> 00:10:31.879 extra tests, like C -reactive protein, some other 00:10:31.879 --> 00:10:34.379 markers of inflammation, some more sophisticated 00:10:34.379 --> 00:10:37.720 markers of stress on the heart, apart from just 00:10:37.720 --> 00:10:39.940 cholesterol. But these are all things that you 00:10:39.940 --> 00:10:42.340 can measure now. which may then, when you see 00:10:42.340 --> 00:10:45.259 your results, motivate you to take a little bit 00:10:45.259 --> 00:10:46.860 better care of yourself or someone you love. 00:10:47.019 --> 00:10:48.659 You know, a lot of listeners are thinking about 00:10:48.659 --> 00:10:50.419 people that they want to help in their lives, 00:10:50.519 --> 00:10:53.399 and I'd love to help you do that if you have 00:10:53.399 --> 00:10:56.299 somebody that you love, your father, your uncle, 00:10:56.419 --> 00:10:58.960 your sister, your cousin, somebody that you know, 00:10:59.000 --> 00:11:01.820 maybe you strongly suspect that could use some 00:11:01.820 --> 00:11:03.980 help, and maybe they're a little reluctant. Maybe 00:11:03.980 --> 00:11:05.860 they don't want to. They don't want to. They 00:11:05.860 --> 00:11:08.480 think they're fine. Everyone thinks they're fine 00:11:08.480 --> 00:11:10.899 until symptoms start. But maybe they've started 00:11:10.899 --> 00:11:12.539 to get a couple of symptoms and you think, man, 00:11:12.559 --> 00:11:14.519 this is a good time. Let's see if we can get 00:11:14.519 --> 00:11:17.200 them to maybe take a couple of steps to improve 00:11:17.200 --> 00:11:20.000 their health. I'd love an opportunity to help 00:11:20.000 --> 00:11:22.899 you help that person. And one of the ways that 00:11:22.899 --> 00:11:25.679 that is made possible is just by simply getting 00:11:25.679 --> 00:11:27.600 them to come in one time. Come into the office, 00:11:27.700 --> 00:11:30.299 get the workup, get the blood tests. Just tell 00:11:30.299 --> 00:11:33.399 them to come check it out. Find out what's really 00:11:33.399 --> 00:11:36.340 happening on the inside with their health right 00:11:36.340 --> 00:11:38.279 now. They don't have to make any grand decisions. 00:11:38.460 --> 00:11:40.480 Maybe they're not going to do anything differently 00:11:40.480 --> 00:11:43.460 at all. Just tell them to get it checked out. 00:11:43.580 --> 00:11:45.320 It's amazing what you can find out on tests. 00:11:45.519 --> 00:11:47.840 And then when you see those numbers, Numbers 00:11:47.840 --> 00:11:50.759 staring you in the face with your number at the 00:11:50.759 --> 00:11:53.139 top of that, your name at the top of that report. 00:11:53.240 --> 00:11:55.360 You know, now you know something's going on, 00:11:55.379 --> 00:11:58.120 something that is worth spending a little time 00:11:58.120 --> 00:12:01.639 investing a little bit in your health now. I'm 00:12:01.639 --> 00:12:03.919 Dr. Todd Binkley. You're listening to Safe, Effective, 00:12:03.919 --> 00:12:06.559 Natural Solutions to Almost Any Health Challenge. 00:12:07.159 --> 00:12:09.460 Today we're talking about how to identify earlier 00:12:09.460 --> 00:12:12.480 signs of risk for dementia, for cardiovascular 00:12:12.480 --> 00:12:14.720 disease, which is always associated with that. 00:12:14.820 --> 00:12:18.000 Common tests that most doctors don't do, but 00:12:18.000 --> 00:12:21.519 which may motivate you and people you love to 00:12:21.519 --> 00:12:23.259 take better care of themselves to prevent the 00:12:23.259 --> 00:12:25.940 risk of this devastating disease. disease called 00:12:25.940 --> 00:12:28.460 Alzheimer's. So one of the other most important 00:12:28.460 --> 00:12:30.940 tests that anyone can do, if you can get your 00:12:30.940 --> 00:12:33.059 doctor to order it, great. If you can't, I can 00:12:33.059 --> 00:12:36.620 order it for you. And that is the APOE gene. 00:12:36.919 --> 00:12:42.500 So the APOE gene, alpo -lipoprotein E, has several 00:12:42.500 --> 00:12:45.980 different forms, E2, 3, and 4. You have two of 00:12:45.980 --> 00:12:48.720 each. It's a little bit technical, but the bottom 00:12:48.720 --> 00:12:50.539 line is if you get that gene test, you can tell 00:12:50.539 --> 00:12:53.840 whether or not you have two twos, two threes, 00:12:53.840 --> 00:12:56.379 two fours, or a combination of a two and a three 00:12:56.379 --> 00:12:59.080 or three and a four. The worst is to have a three 00:12:59.080 --> 00:13:02.179 and a four or two fours, which dramatically increase 00:13:02.179 --> 00:13:05.419 your risk of dementia and further makes your 00:13:05.419 --> 00:13:09.919 risk of getting severe dementia. 25 -fold increased 00:13:09.919 --> 00:13:12.620 risk if you have a head injury, even a mild head 00:13:12.620 --> 00:13:15.559 injury. So one of the things that I always recommend 00:13:15.559 --> 00:13:18.679 that people do when they get this APOE gene test 00:13:18.679 --> 00:13:22.240 and find out that they have the highest tier 00:13:22.240 --> 00:13:27.100 risk factors, three and four, is anytime you 00:13:27.100 --> 00:13:29.700 get even a mild bump on the head, immediately 00:13:29.700 --> 00:13:32.899 take an Advil. or some curcumin, some kind of 00:13:32.899 --> 00:13:35.139 natural anti -inflammatory, or even if nothing 00:13:35.139 --> 00:13:37.500 else is available, even take some ibuprofen to 00:13:37.500 --> 00:13:39.600 immediately blunt that inflammation. Because 00:13:39.600 --> 00:13:42.600 the research has shown that a tiny amount of 00:13:42.600 --> 00:13:45.039 inflammation to your brain, when you have that 00:13:45.039 --> 00:13:48.539 gene profile, dramatically, 25 -fold increased 00:13:48.539 --> 00:13:52.419 risk of developing Alzheimer's. Here's another 00:13:52.419 --> 00:13:54.120 study that just came out, published in May of 00:13:54.120 --> 00:13:58.059 2025, in Alzheimer's and Dementia. where researchers 00:13:58.059 --> 00:14:01.799 did a systematic review of primary studies, genetic 00:14:01.799 --> 00:14:05.019 studies of neuropsychiatric symptoms, mild cognitive 00:14:05.019 --> 00:14:07.659 impairment, and or Alzheimer's dementia, and 00:14:07.659 --> 00:14:11.019 they did genome -wide association studies, G 00:14:11.019 --> 00:14:15.639 -W -A -S, genome -wide association studies, performed 00:14:15.639 --> 00:14:19.100 for psychosis and affective symptoms in Alzheimer's 00:14:19.100 --> 00:14:21.179 dementia with significant associations found 00:14:21.179 --> 00:14:24.340 for psychosis. So what does that mean? Well, 00:14:24.440 --> 00:14:28.110 they're not only... using this data and, you 00:14:28.110 --> 00:14:32.009 know, broad expanses collating a number of different 00:14:32.009 --> 00:14:35.509 studies to just find the risk factors that we've 00:14:35.509 --> 00:14:36.889 been talking about already on this show. But 00:14:36.889 --> 00:14:39.529 they're also looking specifically for things 00:14:39.529 --> 00:14:42.070 that cause an increased risk of some of the most 00:14:42.070 --> 00:14:44.330 devastating effects. Alzheimer's is often worse. 00:14:45.500 --> 00:14:48.860 often, very often worse for the caregivers, not 00:14:48.860 --> 00:14:51.000 for the person who has the dementia so much as 00:14:51.000 --> 00:14:53.179 the person who has to take care of that person. 00:14:53.200 --> 00:14:55.679 When you have to take care of your father or 00:14:55.679 --> 00:14:58.240 your mother or your sister or brother, and they 00:14:58.240 --> 00:15:00.639 don't even know your name anymore, that's the 00:15:00.639 --> 00:15:04.120 worst part. But if they're, that's bad enough, 00:15:04.120 --> 00:15:06.360 even if they don't remember you, but it's so 00:15:06.360 --> 00:15:09.340 much worse if they're agitated and anxious and 00:15:09.340 --> 00:15:13.100 have delusions and hallucinations. So this test 00:15:13.100 --> 00:15:17.159 is showing that this APOE gene, certain variants 00:15:17.159 --> 00:15:19.460 of it, are strongly associated with increased 00:15:19.460 --> 00:15:24.120 risk of agitation, anxiety, apathy, where they 00:15:24.120 --> 00:15:26.799 just don't feel like doing anything, delusions 00:15:26.799 --> 00:15:29.279 and hallucinations, and mild cognitive impairment, 00:15:29.539 --> 00:15:32.820 the early form, and full -blown. Alzheimer's 00:15:32.820 --> 00:15:36.360 dementia. So all of these most devastating effects 00:15:36.360 --> 00:15:40.919 of Alzheimer's are strongly associated with APOE 00:15:40.919 --> 00:15:44.740 gene status. So last time I checked, I can get 00:15:44.740 --> 00:15:50.559 that test for you through LabCorp for $337. And 00:15:50.559 --> 00:15:53.259 some people just don't want to even consider 00:15:53.259 --> 00:15:57.759 it, but I still recommend it. The 23andMe gene 00:15:57.759 --> 00:15:59.860 test. Why do we recommend it? Isn't that a little 00:15:59.860 --> 00:16:02.879 bit scary given some corporation, your DNA, who 00:16:02.879 --> 00:16:05.539 knows what they're going to do with it? As of 00:16:05.539 --> 00:16:08.279 this recording, the company is still in bankruptcy 00:16:08.279 --> 00:16:10.919 proceedings, but there also is rumor. The website 00:16:10.919 --> 00:16:15.879 is still up. You can still order the test. mumblings 00:16:15.879 --> 00:16:17.539 that someone is going to buy it, perhaps even 00:16:17.539 --> 00:16:19.399 the person that originally developed the technology 00:16:19.399 --> 00:16:22.700 that they use. So hopefully it will stick around. 00:16:23.179 --> 00:16:26.019 Hopefully someone will be responsible and maintain 00:16:26.019 --> 00:16:29.100 the privacy of that data and not just exploit 00:16:29.100 --> 00:16:31.190 it like everything else, but I don't know. There's 00:16:31.190 --> 00:16:33.269 so much of that going on right now that we don't 00:16:33.269 --> 00:16:36.590 even know about. And I'm focused on what's beneficial 00:16:36.590 --> 00:16:39.730 to people that I see in my practice right now. 00:16:39.789 --> 00:16:43.629 And for $150, you can get the APOE gene and a 00:16:43.629 --> 00:16:46.629 dozen other really important gene tests for your 00:16:46.629 --> 00:16:49.490 health for $149. So if you've got an unlimited 00:16:49.490 --> 00:16:52.070 budget, you can spend thousands of dollars to 00:16:52.070 --> 00:16:54.070 get the useful information from those tests. 00:16:54.129 --> 00:16:56.029 They are available through other labs, but it's 00:16:56.029 --> 00:16:57.710 just a wealth of information that you can get 00:16:57.710 --> 00:17:02.690 for $149. from 23andMe, including this APOE gene 00:17:02.690 --> 00:17:05.450 test. And if it comes back that your APOE gene 00:17:05.450 --> 00:17:09.210 test status is you have APOE2, variant number 00:17:09.210 --> 00:17:13.190 two, two of those, or one number two and one 00:17:13.190 --> 00:17:15.849 number three, then it means that you have lower 00:17:15.849 --> 00:17:18.569 risk of the worst forms of Alzheimer's. Conversely, 00:17:18.589 --> 00:17:22.250 if you have two fours, two four variants of that 00:17:22.250 --> 00:17:24.730 gene, then you have the highest probability of 00:17:24.730 --> 00:17:27.410 developing dementia and having the worst time 00:17:27.410 --> 00:17:31.220 of it if you do. That's why I love having people 00:17:31.220 --> 00:17:33.720 do this test because when you know that, this 00:17:33.720 --> 00:17:35.920 is well -established research, when you know 00:17:35.920 --> 00:17:39.700 that, and you get it as early as possible in 00:17:39.700 --> 00:17:42.279 your 30s and 40s, hopefully some people will 00:17:42.279 --> 00:17:44.019 be listening or tell somebody earlier because 00:17:44.019 --> 00:17:45.960 most of the people don't even pay any attention 00:17:45.960 --> 00:17:48.799 to dementia until they're in their 60s or 70s 00:17:48.799 --> 00:17:51.319 or 80s. Anyone can get this test now and start 00:17:51.319 --> 00:17:54.359 doing things. Be motivated to do things early 00:17:54.359 --> 00:17:56.440 to reduce your risk because none of it is inevitable. 00:17:56.640 --> 00:17:58.039 The gene doesn't mean that you're definitely 00:17:58.039 --> 00:18:00.289 going to get these. things, it means you're likely 00:18:00.289 --> 00:18:02.950 to, if you're just a member of the standard population 00:18:02.950 --> 00:18:05.589 that eats the standard crappy American diet and 00:18:05.589 --> 00:18:08.029 doesn't exercise that much and has a lot of stress. 00:18:08.089 --> 00:18:10.910 When you see these studies of populations, remember, 00:18:11.170 --> 00:18:13.970 that's studies of general population that don't 00:18:13.970 --> 00:18:16.390 do anything, most of whom don't do anything to 00:18:16.390 --> 00:18:18.809 take care of their health. So if you know that 00:18:18.809 --> 00:18:21.569 you have that gene component of those risk factors, 00:18:21.710 --> 00:18:24.170 then you can motivate yourself and folks that 00:18:24.170 --> 00:18:26.349 you love to take better care of your health and 00:18:26.349 --> 00:18:29.930 beat those odds. I'm Dr. Todd Bankley. You're 00:18:29.930 --> 00:18:31.849 listening to Safe, Effective, Natural Solutions 00:18:31.849 --> 00:18:34.609 to almost any health challenge. I had a few more 00:18:34.609 --> 00:18:37.210 questions after last week's show asking about 00:18:37.210 --> 00:18:39.410 creatine. Where can I find out more information 00:18:39.410 --> 00:18:42.529 about creatine? Well, here's a good source, the 00:18:42.529 --> 00:18:44.789 Mayo Clinic. If you go to the Mayo Clinic and 00:18:44.789 --> 00:18:47.150 just search for creatine, they will tell you 00:18:47.150 --> 00:18:49.049 that creatine is a compound that comes from three 00:18:49.049 --> 00:18:51.109 amino acids. It's found mostly in your body's 00:18:51.109 --> 00:18:53.529 muscles as well as in the brain. And that most 00:18:53.529 --> 00:18:56.920 people get creatine from seafood. and red meat, 00:18:57.059 --> 00:19:00.059 though most people get it at levels far below 00:19:00.059 --> 00:19:05.099 those found in synthetically made creatine supplements. 00:19:05.579 --> 00:19:07.740 Well, you can get creatine supplements that are 00:19:07.740 --> 00:19:09.839 not synthetically made, that are extracted from 00:19:09.839 --> 00:19:12.339 beef, but a lot of people don't like that idea. 00:19:12.579 --> 00:19:15.220 And this is one of the occasions where synthetically 00:19:15.220 --> 00:19:17.380 making it is just a combination of amino acids. 00:19:17.400 --> 00:19:20.259 It's not voodoo science or anything that has 00:19:20.259 --> 00:19:23.599 any problems associated with it. synthetically 00:19:23.599 --> 00:19:25.460 made creatine supplements are vegan. So even 00:19:25.460 --> 00:19:28.119 if you're worried about eating beef or animal 00:19:28.119 --> 00:19:31.000 products, you're fine just to get a powdered 00:19:31.000 --> 00:19:33.240 supplement. The body's liver, pancreas, and kidneys 00:19:33.240 --> 00:19:37.529 can also make about a gram of creatine. And your 00:19:37.529 --> 00:19:40.049 body stores creatine as phosphocreatine, primarily 00:19:40.049 --> 00:19:42.329 in muscles where it's used for energy, which 00:19:42.329 --> 00:19:44.730 is why it's so popular with athletes. People 00:19:44.730 --> 00:19:48.029 also use oral creatine to treat certain brain 00:19:48.029 --> 00:19:50.930 disorders, neuromuscular conditions, congestive 00:19:50.930 --> 00:19:56.190 heart failure, and other conditions. If you look 00:19:56.190 --> 00:19:58.089 up creatine on the Mayo Clinic website, a good 00:19:58.089 --> 00:20:00.529 source of general health information, they also 00:20:00.529 --> 00:20:04.789 remind us that proper hydration is crucial when 00:20:04.789 --> 00:20:07.569 using creatine supplements to minimize the risk 00:20:07.569 --> 00:20:12.230 of dehydration and muscle cramps. If you have 00:20:12.230 --> 00:20:13.910 any other questions about creatine, where to 00:20:13.910 --> 00:20:15.509 get it, what kind to take, how much to take, 00:20:15.569 --> 00:20:17.450 what does it do for you, what should you take 00:20:17.450 --> 00:20:19.549 with it or not with it, or anything that related 00:20:19.549 --> 00:20:21.930 to that or any other aspect of your health, as 00:20:21.930 --> 00:20:25.670 always, please email me your questions at drbinkley 00:20:25.670 --> 00:20:29.670 at binkleyhealingcenter .com. My website is binkleyhealingcenter 00:20:29.670 --> 00:20:33.450 .com. The email is drbinkley. at binkleyhealingcenter 00:20:33.450 --> 00:20:35.829 .com, which is where you can see all, listen 00:20:35.829 --> 00:20:38.609 to all of the past episodes of this show, as 00:20:38.609 --> 00:20:41.490 well as on Apple Podcasts, Spotify, and YouTube. 00:20:41.569 --> 00:20:43.490 You can also text me. I'll give you my cell phone. 00:20:43.710 --> 00:20:46.670 Just be aware that my ringer is always off. That's 00:20:46.670 --> 00:20:48.690 how I'm able to give my cell phone out on air 00:20:48.690 --> 00:20:51.210 because I never answer my phone. If you want 00:20:51.210 --> 00:20:52.450 to talk on the phone, you'll have to leave a 00:20:52.450 --> 00:20:54.029 message and I'd be happy to call you back. But 00:20:54.029 --> 00:20:55.910 you can text me anytime. You won't bother me 00:20:55.910 --> 00:20:57.990 because I'll see the screen light up. And if 00:20:57.990 --> 00:20:59.990 I'm not busy, I'll answer it right away. That's 00:20:59.990 --> 00:21:01.289 the way, that's the fastest way to get a response. 00:21:01.289 --> 00:21:07.430 My cell phone is 805 -218 -3939. Text me your 00:21:07.430 --> 00:21:10.369 questions. I'd be happy to answer them. Finally 00:21:10.369 --> 00:21:13.250 today, there's another great study that came 00:21:13.250 --> 00:21:15.549 out. This is really, I don't know, maybe it should 00:21:15.549 --> 00:21:17.609 be surprising. It's actually not that surprising 00:21:17.609 --> 00:21:20.230 to me because I test toxins in a lot of people. 00:21:20.549 --> 00:21:22.869 A lot of people have heard about the effects 00:21:22.869 --> 00:21:25.410 of toxins. A lot of people have educated themselves 00:21:25.410 --> 00:21:28.390 to become really concerned about it. And then, 00:21:28.430 --> 00:21:31.089 you know, most of us think, well, toxins are 00:21:31.089 --> 00:21:32.390 everywhere. What are you going to do? How do 00:21:32.390 --> 00:21:34.710 I even know if they're impacting me? Well, how 00:21:34.710 --> 00:21:37.670 you know is you get tested. You can measure your 00:21:37.670 --> 00:21:40.509 body's burden of heavy metals like lead, mercury, 00:21:40.730 --> 00:21:43.450 arsenic, cadmium, and uranium by doing a hair 00:21:43.450 --> 00:21:46.369 test. This stuff is excreted through your sweat 00:21:46.369 --> 00:21:49.109 glands and hair follicles. It accumulates in 00:21:49.109 --> 00:21:50.930 your hair as it grows out, which can be collected 00:21:50.930 --> 00:21:53.009 and sent into a lab. That's why they use hair 00:21:53.009 --> 00:21:55.210 for drug testing, similar mechanism. And you 00:21:55.210 --> 00:21:57.470 can also do a urine test to measure your body. 00:21:57.390 --> 00:21:59.890 body burden of heavy metals, they don't show 00:21:59.890 --> 00:22:02.369 up on blood tests so well. If you have heavy 00:22:02.369 --> 00:22:04.630 metals showing up in a blood test, then that 00:22:04.630 --> 00:22:06.150 usually means you've had a really significant 00:22:06.150 --> 00:22:09.809 or ongoing recent exposure or an ongoing exposure, 00:22:09.910 --> 00:22:12.069 which is really bad. But lots of people show 00:22:12.069 --> 00:22:17.319 low or below range. tests for those heavy metals 00:22:17.319 --> 00:22:19.200 on a blood test. And yet when you take those 00:22:19.200 --> 00:22:21.440 same people and do a hair test or a specific 00:22:21.440 --> 00:22:24.619 type of urine test, you'll find that these things, 00:22:24.660 --> 00:22:27.440 because they're stored in fat cells and not circulating 00:22:27.440 --> 00:22:30.140 in your blood, that people have more than they 00:22:30.140 --> 00:22:31.640 know about it. And when you find that out, you 00:22:31.640 --> 00:22:33.740 can do something to release it. So here's a study 00:22:33.740 --> 00:22:36.640 that was published in JAMA, Journal of the American 00:22:36.640 --> 00:22:40.019 Medical Association, living within one mile of 00:22:40.019 --> 00:22:43.000 a golf course. was associated with double the 00:22:43.000 --> 00:22:45.299 odds of developing Parkinson's disease. So we've 00:22:45.299 --> 00:22:47.880 been talking about Alzheimer's, but Parkinson's 00:22:47.880 --> 00:22:50.880 disease is another neurodegenerative condition, 00:22:51.019 --> 00:22:52.640 obviously a completely different disease, but 00:22:52.640 --> 00:22:55.079 when it comes to the things you can do to prevent. 00:22:56.029 --> 00:22:58.009 neuro -generative conditions, there's a lot of 00:22:58.009 --> 00:23:00.269 overlap. So all the things that you can do to 00:23:00.269 --> 00:23:03.130 reduce your risk of Alzheimer's disease will 00:23:03.130 --> 00:23:05.529 also tend to reduce your risk of Parkinson's. 00:23:05.549 --> 00:23:08.750 And that includes avoiding exposure to these 00:23:08.750 --> 00:23:12.849 toxins. So the odds of living within a mile of 00:23:12.849 --> 00:23:15.930 a golf course because of the pesticides and other 00:23:15.930 --> 00:23:18.549 toxic chemicals they put on the grass to keep 00:23:18.549 --> 00:23:20.470 that lawn so pretty and clean. Living within 00:23:20.470 --> 00:23:22.009 a mile of a golf course is more than double the 00:23:22.009 --> 00:23:23.950 odds of developing Parkinson's disease compared 00:23:23.950 --> 00:23:26.670 with living six miles. So just the difference 00:23:26.670 --> 00:23:28.809 between two miles away and six miles away of 00:23:28.809 --> 00:23:31.950 a golf course doubles your risk of developing 00:23:31.950 --> 00:23:35.150 Parkinson's disease. This is published by Dr. 00:23:35.509 --> 00:23:40.410 Brittany Krzyzewski. PhD of the Barrow Neurological 00:23:40.410 --> 00:23:42.950 Institute in Phoenix, reported in JAMA this past 00:23:42.950 --> 00:23:46.150 month, May of 2025. It was a study done in Minnesota 00:23:46.150 --> 00:23:50.829 involving 419 Parkinson's cases and over 5 ,000 00:23:50.829 --> 00:23:54.410 controls, median age 72. This was done over several 00:23:54.410 --> 00:23:58.049 years, from 1991 to 2015. They collected data 00:23:58.049 --> 00:24:03.269 from 139 golf courses and 224 water services 00:24:03.269 --> 00:24:06.569 areas. So the odds of getting Parkinson's disease. 00:24:07.610 --> 00:24:11.710 decreased by 9 % for every mile increase in the 00:24:11.710 --> 00:24:15.329 distance from a golf course up to 18 miles. Wow, 00:24:15.450 --> 00:24:17.549 that's pretty eye -opening. I got so entranced 00:24:17.549 --> 00:24:19.430 with it that I didn't just realize we're about 00:24:19.430 --> 00:24:21.730 out of time. So do something this week to be 00:24:21.730 --> 00:24:24.529 healthier than you were last week. Have a wonderful 00:24:24.529 --> 00:24:27.890 weekend. You've been listening to Safe, Effective 00:24:27.890 --> 00:24:31.220 Natural Solutions with Dr. Todd Binkley. If you 00:24:31.220 --> 00:24:33.180 have a health question you want discussed on 00:24:33.180 --> 00:24:36.559 the show, email your health questions to drbinkley 00:24:36.559 --> 00:24:40.559 at binkleyhealingcenter .com. Take advantage 00:24:40.559 --> 00:24:43.359 of this opportunity to ask questions for yourself 00:24:43.359 --> 00:24:46.940 and for your loved ones because our health matters. 00:24:47.180 --> 00:24:51.799 Join him next Friday at 2 p .m. for Safe, Effective 00:24:51.799 --> 00:24:56.039 Natural Solutions here on 98 .3 FM, The Word.