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Prepare to have your health questions answered here on Safe, Effective, Natural Solutions

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with Dr. Todd Binkley, owner of Binkley Healing Center in downtown Ventura.

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Now here's Dr. Todd.

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Good afternoon.

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I'm Dr. Todd Binkley, board certified non-force doctor of chiropractic and practitioner of

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functional medicine.

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Functional medicine means using standard diagnostic tests to identify conditions that other doctors

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have missed.

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The last couple of episodes we were talking a lot about the microbiome.

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This is something that actually affects today's topic, but the focus is going to be, and it's

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kind of complex, but a lot of people are concerned about dementia, cognitive decline, cognitive

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impairment, Alzheimer's disease, etc.

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So the title for today's talk is Dementia, Diabetes, and Cardiovascular Disease Inextricably

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Linked.

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You can't have one without the other.

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They go together.

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And the sad thing is most people wait until they have severe signs of cognitive decline,

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memory loss, dementia, before they consider doing anything about it.

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So how do you know if you really need, you know, ideally everyone should start doing

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something about it in their 30s.

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And that's just probably never going to happen.

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You definitely don't want to wait until your 70s or your 80s, especially if you already

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have a familial history of risk for, you know, if one of your parents had severe dementia,

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then there's a hint to start earlier identifying risk factors, things that can be mitigated

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in advance.

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Here's something that anyone can do.

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The APOE gene test, apolipoprotein E gene test.

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There's three different versions that are the result from the test, two, three, or four.

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And we have two, we have a pair of each.

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So the results are going to say that you have, you know, APOE two and two, three and three,

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four and four, two and four, two and three, three and four, et cetera.

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You get, you have two and they're, each of them is either going to be two, three, or

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four.

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So it's a little tricky, but the thing, the takeaway is folks who have APOE two, fours,

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two examples of the APOE four gene test are at the highest risk of dementia.

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So it's really important to know if you're one of those people, because your risk is

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dramatically increased and it would behoove you, hopefully motivate you to do some things

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earlier to reduce your risk.

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So that test used to cost seven or $800.

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I just checked today, it's down to $340 now through LabCorp, which is still pretty expensive

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for one gene test.

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Some people are a little reluctant to do 23andMe gene testing for a host of reasons, but you

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know, I figure, yeah, you've got to worry about how they're going to protect your data,

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but they've done a pretty good job of it so far.

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And I think if they ever abuse it, that someone could run and win a Senate campaign to crack

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down on any transgressions they might have made.

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So that's a little bit of diversion.

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23andMe, what's great about this health test, not the hereditary, where do your ancestors

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come from, but 23andMe offers for $149 a whole slate of gene tests that individually cost

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hundreds of dollars each.

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So it's thousands of dollars worth of gene tests that are really useful, including the

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Alzheimer's gene, blood clotting factors, hemochromatosis, iron overload, a whole host

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of other genes.

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You can look them up on their website.

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And it's just a huge bargain for $149.

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And when I test people, when I do people's blood tests or when they come in with certain

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conditions, I often ask them, have you done the 23andMe gene test?

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Because that can provide some information that we can use.

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Is this a genetic condition for you or just the result of your diet or your lifestyle?

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So that's really helpful.

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And one of the reasons that's helpful is outlined in a study that just came out last week and

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published in the Journal of the American Medical Association, showing the benefits of taking

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fish oil supplements to reduce your risk of brain damage that causes cognitive decline.

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So this was just published August 1st in JAMA, Journal of the American Medical Association,

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older adults with lower intake and tissue levels of these two main omega-3 fatty acids,

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EPA and DHA, that you can only get from fish oil.

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The people they tested that had, they gave a certain amount of this, and I'll get back

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to that, had more, who didn't have adequate levels of this, had more white matter, brain

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white matter lesions, which is associated with small vessel ischemic disease, basically

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loss of blood flow to the tissue of the brain so that it can heal and repair itself.

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And that is a major contributor to the development of dementia, including Alzheimer's disease.

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And this study showed may be preventable through treatment with omega-3 fatty acids from fish

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oil.

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So the people who tested with two APOE4 genes, carriers of that gene pattern, had significant

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reductions in neuronal integrity breakdown over three years by supplementing with fish

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oil.

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And these were participants with an average age of 81 years old that already had white

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matter lesions on their MRI, the early signs that you can see on a scan of the damage to

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the brain that causes dementia.

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And it was a pretty modest intake of fish oil that this study used, 1.65 grams, a little

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more than a gram and a half, a little more than 1,650 milligrams specifically, of combined EPA and DHA,

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the two important omega-3 fatty acids that you can only get from fish oil.

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You can't get any significant amount of EPA or DHA from any vegetable source, from chia

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seeds or flax seed oil or any of these other vegetable-based oils.

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You can get it from algae, but it's very expensive, two and a half times the cost of getting it

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from fish oil.

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So the easiest way to get EPA and DHA, these brain-protective omega-3 fatty acids, is from

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eating fish, oily fish like sardines and chauvis, salmon and tuna.

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But the problem is with salmon and tuna, eating too much tuna, unless you're getting small

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pole-caught smaller fish that are tested to be lower in mercury, which you can get in

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a can.

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The brands that you can get in cans in stores, vans or standard stores, Wild Planet and Safe

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Cats you can get tuna, which is a great source of omega-3s and has lower mercury than eating

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tuna in a restaurant or getting the chicken of the sea canned tuna or basically any other

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kind of tuna.

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Even fresh-caught fish, if it's a big fish, it's going to be high in mercury.

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And so salmon also has a lot of omega-3s in it, but unfortunately most of the salmon that

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we eat is farm-raised and that has a host of other problems as well.

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So if you get fresh-caught salmon, which you can often get frozen in stores or some restaurants

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serve wild-caught salmon, that's also an excellent source.

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It's always great to get everything you can from food, but it's so difficult for most

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people to get enough omega-3 fatty acids from ocean-based foods that I recommend almost

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everyone supplement fish oil to get the omega-3s they need to protect their brain, also to

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protect their heart and a whole host of other inflammatory-based conditions.

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For years it's been difficult to tell if you have early onset dementia or document the

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state of your brain as regards the degradation that causes dementia and there's a new blood

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test out from, it's called the Perclivity A-D2 blood test, which includes an algorithm

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that measures your level of the damaging tissues in the brain, things like amyloid plaque and

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neurofibular tangles.

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It's a little technical, but basically it measures these things in the blood and several

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things and then measures the level of them compared to a standard.

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And this is a test that's been out for a while and the results of its use was recently published

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at the Alzheimer's Association International Conference, a study presented by Oskar Hansson,

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MD, PhD from Skein University in Sweden and it was also published in the Journal of the

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American Medical Association.

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So this blood test had a diagnostic accuracy of 91% compared with 61% diagnostic accuracy

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after standard clinical evaluations by primary care physicians and compared to 73% accuracy

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after evaluations by dementia specialists, usually neurologists.

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So this is a very exciting test.

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It is available now at Perclivity Labs by C2N Diagnostics.

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I just went on their website earlier today to find out pricing.

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I haven't heard back from them yet, but I hope to have pricing for this soon.

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It's probably not cheap, but like all tests like this, they become less expensive as time

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goes by.

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And just based on the fact that it has a diagnostic accuracy of 91% compared with 61% to 73% with

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standard methods that most physicians are using now and the amount of money that could

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be saved by potentially treating this earlier, argues that it could probably become a standard

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test that's available through insurance eventually.

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But things like this can take a few years for that to happen.

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So stay tuned.

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I'll let you know as soon as I know what the pricing is on that.

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Here's another really exciting test.

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Intermittent fasting may improve memory and executive function.

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So these are measures, obviously measures of things that have to do with dementia.

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So what is intermittent fasting?

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Intermittent fasting means usually trying to avoid eating more than a certain number

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of hours per day.

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So there are lots of different kinds of fasts where people don't eat all day, sometimes

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even for days at a time.

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This is not that.

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The intermittent means regularly not eating for 16 hours a day, for example, trying to

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get whatever meals you're going to have in an eight hour period, sometimes a little bit

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longer.

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For example, just eating breakfast and lunch.

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Unfortunately, it's more common for people to skip breakfast and only eat lunch and dinner.

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But the one meal that you need the least is the one that you eat right before you go to

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bed.

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So if you're eating dinner at five o'clock and lunch at 12, then that's not a bad way

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to do it.

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But if you're eating lunch at 12 or one and dinner at eight, that's not such a great way

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because you don't need food to sleep.

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So there's lots of information available on the internet about intermittent fasting.

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And this trial that's exciting because of the effects it has on improving memory and

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executive function.

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These are two markers for brain health.

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It was an eight week randomized clinical trial, a small trial of 40 overweight cognitively

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normal older adults with insulin resistance.

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And they basically did one of two things.

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Half of them were on a quote unquote healthy living diet based on portion controlling calorie

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restrictions.

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So basically just on a low calorie standard weight loss diet.

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The other half was on the same diet for five days a week and just two days a week.

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Only two days a week they did two meal replacement shakes, 480 calories a day.

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And the rest of the five days they did the same diet as the other group.

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So just two days out of a week doing this calorie restricted meal intermittent fasting

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to two meal replacement shakes per day had a significant difference in improved executive

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function and memory.

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And the intermittent fasting showed better results on cognitive measures.

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This test was done by the by a reported by Demetrios Kapogiannis, MD of the National

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Institutes on Aging and John Hopkins University School of Medicine in Baltimore and presented

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at the Alzheimer's Association International Conference.

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It was also published in Selmitasinolent Tabulism.

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So it was a small study and then obviously, well I would imagine lots of other studies

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have given us reason to believe that a more typical intermittent fasting program where

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you're most days, not just two days a week, but most days restricting the two meals a

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day that you eat or you know a number of smaller meals to an eight hour window and then not

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eating for 16 hours to let your body break down and digest and assimilate all of that

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food has a huge impact on your health including your brain.

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I'm Dr. Todd Binkley.

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You've been listening to safe effective natural solutions to almost any health challenge.

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Today we're talking about dementia, diabetes and cardiovascular disease and how these three

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are inextricably linked.

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You can't have one without the other.

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So you know we're all familiar, hopefully we're all familiar with the causes of diabetes,

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eating too much sugar, not exercising enough, obesity and you know the causes of cardiovascular

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disease are pretty familiar to most people.

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Not enough exercise, not enough healthy food to keep your heart strong, some of the lesser

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common causes of cardiovascular.

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One of the things that most people hear about for cardiovascular disease is high cholesterol.

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Everyone needs to take a statin drug to keep their cholesterol down.

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Not true.

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I've talked about that over and over and over again but these three things are linked and

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there are some uncommon causes of heart disease and diabetes that you may not have heard of.

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So just recently this came out in the medical literature, the effect of heavy metals predicting

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risk of heart disease.

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So cadmium, tungsten, uranium, cobalt, copper and zinc.

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Increasing levels of these six metals on urine testing were associated with 29% more cardiovascular

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disease and 66% all cause mortality after accounting for demographic lifestyle and other

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clinical risk factors.

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And cadmium and copper showed a direct relationship with both cardiovascular disease and mortality.

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This is reported by Irene Martinez Morata, MD, PhD of Columbia University and the School

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of Public Health in New York City.

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Reported in the journal Circulation.

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So quote, this is her quoting, our findings support the fact that urinary metals are a

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robust predictor of cardiovascular risk and all cause mortality and these associations

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with these clinical events, heart attacks, etc., are consistent with a previous finding

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that these same six metals were associated with higher levels of coronary artery calcification,

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supporting the idea that atherosclerosis, hardening of the arteries, is a major underlying

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pathway explaining the association between metals and heart disease.

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So let's just review that again.

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This is a major journal.

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Circulation is a very prestigious journal for cardiology and they're finding that these

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heavy metals that we're all constantly exposed to increase cardiovascular disease, all causes

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of mortality and specifically coronary artery calcification, the hardening of the arteries

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that underlies most heart attacks and can cause strokes.

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So these heavy metals, cadmium and uranium, are two really common toxic metals that have

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been known, the effects of these are well known, have been tested.

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Four years prior, studies have established that arsenic, cadmium, and lead, are contaminant

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metals and exposure to them, are now considered a cardiovascular risk factor by the American

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Heart Association.

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Functional practitioners like myself have long known that the big five heavy metals

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we're always looking for when we test for heavy metals are lead, mercury, arsenic, cadmium,

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and uranium.

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So we're all exposed to those to varying degrees and most of us never test for those things

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and have no idea how much of those we're carrying in our bodies.

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The only way you know is to test.

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They don't necessarily cause any symptoms until they get really bad.

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So it's important, it's really a good idea for everybody to get tested for heavy metals

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and the test for that is either a hair test or a urine test.

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Check out my past episodes.

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If I haven't already, I should remind everyone that all the past episodes of this show are

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available as podcasts.

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You can listen to them anytime you want.

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You can find them on my website, binkleyhealingcenter.com.

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They're right on the homepage, easy to find.

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If you use Apple podcasts or Spotify, they're there.

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Just Google my name, Binkley, and they usually come up or the title of the show, Safe Effective

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Natural Solutions.

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The past episodes are also on YouTube.

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If you search for my name or Safe Effective Natural Solutions.

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They're not always in order on YouTube and there's no video.

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It's just they make a little video of a bouncing this or that, but you can listen to them there

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as well.

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So anyway, previously I've talked a lot about heavy metal toxicities and this is a relatively

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new study that just came out talking about the connection between our exposure to toxic

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heavy metals like cadmium, uranium, and cardiovascular health.

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So they also mentioned cobalt, which is in vitamin B12, copper, and zinc.

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So these are essential minerals that we depend on for life, but like iron, you can get too

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much of them.

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And these are also urine tests without any kind of a provocation or a chelating agent

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to draw them out.

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And again, that's a little technical, but the authors of this study are saying in this

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study, they say, well, it's right here, the copper, zinc, and cobalt authors explained

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that these essential metals are tightly regulated in the body and elevated levels in the urine

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may just represent early cardiometabolic dysregulation.

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So they may just represent a diseased state.

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Your body's increased amount of these things being flushed out is a result of disease,

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not necessarily the cause.

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Whereas toxic heavy metals like cadmium, uranium, and arsenic are well known to cause these

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diseases.

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One of the most common sources of cadmium, which is a known carcinogen, is smoking.

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Smoking tobacco is full of cadmium, but it's in ceramics and certain industrial chemicals.

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There's Google sources of cadmium.

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It's in a lot of things.

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It's possible to avoid all of these things.

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We're exposed to them to greater or lesser degrees.

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Cadmium also affects the kidneys and the liver and the lungs.

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So I was surprised to hear about tungsten.

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So tungsten is on the test.

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It's not something that's been in the research for a long time, but similar evidence of harm,

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according to this article, is some things that are commonly exposed.

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People in the US are commonly exposed to all of these from drinking water, food, air pollution,

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and indoor dust.

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So heavy metals are an lesser known contributor to cardiovascular disease that is becoming

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the significance of which is becoming better known and better documented.

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And anything that causes heart disease causes dementia.

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There's several different types of dementia that have been identified by neurologists

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and pharmaceutical companies that are trying to come up with different drugs to attack

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these different various types.

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Maybe it's important to make the, well, it's apparently important to make those distinctions.

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Louie, do you have Louie body dementia or frontal lobe dementia or classical Alzheimer's

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or vascular dementia?

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For the purposes of healing yourself and providing nutrients to heal your brain, the solution

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is the same.

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Anything that helps prevent heart disease helps prevent brain disease.

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All forms of dementia are in part, if not mostly, vascular disease.

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Your brain loses, tissue is damaged, cells are lost, scar tissue builds up to replace

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that damaged tissue from inflammation and lack of nutrients because of vascular disease,

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the same vascular disease that cause heart attacks and strokes.

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The calcification that builds up and clogs the arteries and prevents adequate nutrition

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to the brain is mainly what causes the slow decay and loss of brain cells in the tissue

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that leads to dementia.

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So anything that causes heart disease will contribute to loss of brain cells and neurodegenerative

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diseases like Alzheimer's and Parkinson's and any other neurodegenerative disorder in

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the brain.

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Here's another unusual, so most people know the causes of diabetes, eating too much lousy

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food, especially sugar laden foods, but artificial sweeteners are often used by some people as

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an alternative to sugar.

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Here's an article that just came out.

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Do artificial sweeteners really help people with diabetes?

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A recent review led by researchers in Mexico concluded that sucralose, which is Splenda

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is the brand name, is associated with various adverse health effects.

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Despite being considered safe in previous studies, the recent research suggests possible

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links to systemic inflammation, metabolic diseases, meaning diabetes mainly, disruptions

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in the gut microbiome, liver damage, and toxic effects at the cellular level.

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Quote, it is crucial to highlight the persistence of sucralose Splenda in the body and its ability

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to cross the placenta and its presence in breast milk, raising concerns about prenatal

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and neonatal exposure.

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Well, this is really important because a lot of women get gestational diabetes.

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They get diabetes when they're pregnant and they may be using these, using sucralose and

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these other alternative sweeteners that are not healthy to reduce their sugar intake.

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So there's better ways to do that.

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We're going to run out of time here to get into all of those things.

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But there's a whole other article here that I'll come to.

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I thought I had it here, but I'll have to come back to that.

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But xylitol is a sugar alcohol that is in a lot of alternative sugar-free things.

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It's in toothpaste.

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The small amounts in toothpaste are not really a big deal, but I'll try and find that and

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talk about it on another episode.

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Xylitol, you don't want to consume lots of that either.

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So the takeaway is anything that causes heart disease, diabetes contributes to heart disease.

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Alzheimer's is often now being called type 3 diabetes because the high blood sugar that

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damages blood vessels to the brain also dramatically contributes to dementia.

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So send me your questions about this and any other subject that we've talked about or any

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other health concern that you have.

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I really appreciate you tuning in.

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And you can reduce your risk of heart disease, diabetes and dementia by eating better food,

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getting a little bit better exercise.

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If it's hard for you to exercise, get the relief from pain that you need.

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Contact me about that as well.

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I am a non-force chiropractor.

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I can help with pain as well.

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And I'd love to help you or someone you love get back to feeling the way they should.

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See if you can do something this week to be healthier than you were last week.

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Have a fantastic weekend.

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You've been listening to Safe Effective Natural Solutions with Dr. Todd Binkley.

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If you have a health question you want discussed on the show, email your health questions to

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drbinkley at binkleyhealingcenter.com.

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Take advantage of this opportunity to ask questions for yourself and for your loved

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ones because our health matters.

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Join him next Friday at 4 p.m. for Safe Effective Natural Solutions right here on 98.3 The

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Word KDAR.

