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Prepare to have your health questions answered here on Safe, Effective, Natural Solutions

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with Dr. Todd Binkley, owner of Binkley Healing Center in downtown Ventura.

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Now, here's Dr. Todd.

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Good afternoon.

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I'm Dr. Todd Binkley, board certified doctor of non-force chiropractic and practitioner

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of functional medicine.

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Functional medicine means using the same tests all doctors use, but instead of using tests

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to diagnose and treat disease that you already have, practitioners of functional medicine

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use the same tests, usually more of them, and a different yardstick, a better way of

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measuring for normal health, for places where normal function has started to fail, where

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things are no longer working as they should.

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Guess what?

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When things aren't working as they should, you don't feel the way you should feel, and

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the reasons for that are identifiable with standard testing, but with measuring for different

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levels of certain things on those tests where normal function is lost.

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Not bad enough to require a prescription or a referral to a specialist or a scan, but

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just things that aren't the way they used to be when you were in your 20s, when you

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were teens, when everything is working perfectly, that can be remedied with better food, exercise,

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and supplements.

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One of the most important realms of human health and healing and disease where this

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is just hugely applicable and can make such a big difference is with hormones.

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So today we're going to talk about hormones.

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I'm going to present a really exciting case about a 58-year-old female with overwhelming

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stress and fatigue and brain fog and irritability.

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These were her main symptoms.

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There were several others, and she got amazing results.

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Once we did comprehensive testing to identify the things that needed support in her body.

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We're also going to talk about the most appropriate forms of testing for hormones in particular.

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Gold standard for most tests is blood.

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Blood tests are the gold standard for most conditions, but there are important exceptions.

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Intestinal pathogens don't show up on a blood test.

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Metallic toxicities, mold exposure, heavy metal toxicities, and importantly, hormones,

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especially estrogen, progesterone, and testosterone.

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These hormones for menopausal symptoms for men with low testosterone and women with perimenopause,

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menopause, and postmenopause.

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The best way to often, the best way to test for these is not with a blood test.

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Your hormones in your blood, your serum levels, you're actually measuring serum levels.

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And these, if you look at a graph of serum levels of estrogen and progesterone, they're

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up and down, up and down, up and down, all day long, every 10 minutes for six hours.

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I'm looking at this graph and it's just up and down.

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It's all over the place.

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So when you do a serum test of that, you're getting a snapshot in time of something that's

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constantly changing.

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So it's better for women with menopausal symptoms to test for their hormones with a saliva test.

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And there's a lot of great things about that.

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Number one, you don't have to get a blood draw.

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Saliva test is measuring an average of your levels of these hormones throughout the entire

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day.

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And if you're going to address any deficiencies in these hormone levels with transdermal creams

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or oils, other transdermal remedies, which is the most common way to do it, then it's

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much better to measure the levels that you have currently with the salivary test because

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that will also show how you're responding to the treatment.

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When you treat hormones with transdermal therapies, the levels that show up in serum do not accurately

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reflect what's happening in your body, whereas a salivary test does.

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So we'll talk about that a little bit later.

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But first I want to dive into a headline in the medical literature that came out this

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week.

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Two, the headline is ovarian cancer risk doubled by estrogen only HRT.

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Hormone replacement therapy.

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So estrogen only without progesterone, hormone replacement therapy doubles the risk of ovarian

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cancer risk.

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This is from two decades after the landmark women's health initiative, which changed the

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way clinicians thought about hormone replacement therapy and cancer from two of the WHO's

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randomized trials, which found that estrogen alone in women with prior hysterectomy significantly

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increased ovarian cancer incidence and mortality in post menopausal women.

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So estrogen and progesterone together did not increase ovarian cancer risk and significantly

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reduced the risk of endometrial cancer.

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So this is by Dr. Rowan Chablowski and presented these results at the annual meeting of the

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American Society of Clinical Oncology.

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Rowan Chablowski, MD, PhD, presented these findings at the American Society of Clinical

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Oncology and he and his colleagues conducted an analysis from two randomized placebo controlled

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trials which between 1993 and 1998 enrolled nearly 28,000 post menopausal women aged 50

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to 79 years without prior cancer from 40 centers across the United States.

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From one of these trials, 17,000 women with a uterus were given equine estrogen plus synthetic

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progesterone standard hormone replacement therapy, Premprote.

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So horse urine plus synthetic progestin.

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This was the standard hormone replacement therapy for decades.

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And another trial, 11,000 women with a hysterectomy were given estrogen alone or a placebo.

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Both trials were stopped early because the estrogen only trial caused an increased stroke

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risk and the combined therapy of horse urine, estrogen, and synthetic progestin caused an

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increased risk of breast cancer and cardiovascular disease.

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So 20 years later, 20 years follow up, this is what they just did, the mortality information

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available suggested that ovarian cancer doubled among the women who had taken estrogen alone.

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Conjugated equine estrogen, horse urine, estrogen, Dr. Chablowski reminded everyone at his presentation

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in Chicago, was introduced in the US clinical practice in 1943 and used for over half a

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century.

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So the question of its influence on endometrial and ovarian cancer, he says, remains unsettled.

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Endometrial cancer and ovarian cancer are the fourth and fifth leading causes of cancer

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deaths in women and horse urine, estrogen reduces the risk of one and increases the

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other.

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Well, to add to confusion oncologist Eleanor Tepelinsky, MD of Valley Mount Sinai Comprehensive

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Cancer Care in New Jersey said that 20 years ago, the women's health initiative showed

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that hormone replacement therapy increases breast cancer risk.

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So everyone stopped taking hormone replacement therapy.

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And now people are pushing back and saying, wait a second, it was estrogen plus progesterone

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that increased breast cancer, not estrogen alone.

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So what's the problem with this?

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Well, the problem is many doctors are more likely now to prescribe estrogen only and

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unopposed estrogen, estrogen without adequate progesterone to balance it out, creates a

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lot of problems.

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It is one of the main things a functional practitioner is looking for when we test your

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hormone levels.

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Progesterone reduces the risk of ovarian cancer and the increased risk of breast cancer, even

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when taking synthetic progestin, progestin, synthetic progestin instead of natural progesterone

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was always minimal.

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The risk, the increased risk in breast cancer of taking even the horse urine, pro, pro,

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prem pro.

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Premorin is horse urine.

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That was the brand name for horse urine estrogen and prem pro was the brand name of the combination

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of horse urine estrogen and synthetic progestin.

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Even when taking that, the increased risk of breast cancer was minimal, equivalent to

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the increased risk of drinking one or two glasses of wine per night, equivalent to the

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risk of inactivity or just being overweight.

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So if there's this much confusion among mainstream doctors, whatever primary care provider may

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be your regular doctor, your internist or your gynecologist or gastroenterologist, let

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alone endocrinologist, how are you, if the doctors are this confused about it, how are

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you supposed to figure out what's best for you?

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Well, before we get to that, here's another excellent article that just came out, headline,

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don't fear hormone replacement therapy, but prescribe it correctly.

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So this is Dr. Dr. Rachel Rubin MD, urologist and sexual medicine specialist.

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She says menopausal complaints are not just hot flashes and night sweats.

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We see so many sexual health problems, genitourinary syndrome of menopause, low libido, pain with

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sex, arousal disorders, orgasm disorders.

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And so she interviewed Stephanie Goubian, director of the Mayo Clinic, women's health

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and medical director for the Menopause Society.

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And so Dr. Fabiana, the Mayo Clinic says the women's health initiative came out, study

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this women's health initiative study, the one I was talking about a little bit earlier

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came out in 2002.

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And after that, we quote, really left women with few choices about what to do, how to

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manage their symptoms, which created a huge vacuum.

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Basically after that clinicians decided they no longer needed to worry about being educated

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about menopause because there was really nothing to do for menopause.

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And we weren't going to use hormone replacement therapy.

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And where we've come is now women are having symptoms.

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They're having a problem.

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I'm still quoting Dr. Stephanie Fabiana of the Mayo Clinic.

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It's affecting all aspects of their lives, their relationships, their quality of life,

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their ability to work.

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And they're saying, Hey, this isn't right.

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We need to do something about this.

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There's still very little research in this area.

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We have a lot more to do and they're demanding answers as they should.

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So says Stephanie Fobion, director of the Mayo Clinic for Women's Health and medical

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director of the Menopause Society.

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And she's being interviewed in this article by Dr. Rachel Rubin.

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So Dr. Rubin says we have a lot of tools in our toolbox that are evidence-based that really

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work and help people.

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We can help these people.

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I always say to my patients, you have a generation of clinicians who were not taught how to do

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this well.

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Hormones are not all good or all bad, all right or all wrong, but they require some

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understanding of when to use them and how to safely use them.

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Because women are being underserved.

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Menopause is not just about hot flashes.

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There's sleep disturbance, mood symptoms, irritability, just not feeling right.

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She talks a lot about one of the main complaints of women, postmenopausal and postmenopausal

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women walking into her office.

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One of the main things they always say is, I just don't feel right or I feel anxious.

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And joint aches also enter the picture quite frequently.

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So it's important, she's saying it's important to remember that estrogen affects every tissue

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and organ system in the body.

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And when you lose it, you have effects in pretty much every system and organ tissue

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in the body, which is really important because we're speaking to the primary care world.

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This is Dr. Rubin, I'm still quoting Dr. Rubin.

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The way medicine is set up, you're allowed to have one problem.

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But menopause is never one problem.

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These women are getting diagnosed with a mental health condition, with fibromyalgia, with

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dry eyes, with sexual dysfunction, with depression or anxiety.

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They're getting 10 diagnoses for what is actually one underlying hypogonadal problem, a lack

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of hormones.

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So Dr. Fabian from the Mayo Clinic says, at the Mayo Clinic, a physician came to see me

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as a patient.

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An internist traveled across the country because she's gaining weight, she's losing her hair,

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she's sweating.

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She thinks there's something horribly wrong with her, like she must have cancer or something.

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But when you put it all together, the palpitations and the rest, it was all menopause.

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Think of the expense to come to the Mayo Clinic and be evaluated for that.

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But no one, including this practicing physician, had put together that all of these symptoms

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were related to menopause.

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Dr. Rubin goes on to say that primary care physicians were raised on the idea that hormones

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cause cancer.

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Well, what are the data in 2024?

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Am I going to die if I take hormone replacement therapy?

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Am I going to risk blood clots and horrible cancers?

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Dr. Fabian of the Mayo Clinic replies, when it comes down to cancer risk, the Women's

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Health Initiative found that if you have a uterus and you're taking both estrogen and

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progesterone, specifically horse urine and synthetic progesterone, the risk for breast

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cancer was slightly increased.

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And when I say slightly, I'm talking about the increased risk of, I mentioned this before,

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this doctor from the Mayo Clinic suggests that that slight increased risk was really

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equivalent to drinking a couple glasses of wine a night or being overweight.

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One case per thousand women per year after about five years of hormone therapy.

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So it was a very small increased risk.

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In contrast, the data showed that the risk for breast cancer did not appear to be increased

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in women who did not have a uterus.

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And the blood clot risk associated with estrogen hormone therapy can be minimized with transdermal

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preparations of estrogen, particularly with low doses.

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So I'm going to come back on that.

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That's a really important point.

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All of these risk factors are from the Women's Health Initiative are studying the effects

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of horse urine estrogen and synthetic progestin, which is not, it's not even the same chemical

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as progesterone.

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So when you do transdermal therapies of plant-based estrogens and progesterone, most of these

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risks go away, especially when you're using really low doses, which often work better

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than the high doses of standard hormone replacement therapy, as most people know it.

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So Dr. Rubin goes on, we can learn new things, right?

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By adding back hormones, maybe we can keep muscles around, keep mental health better,

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keep bones stronger because osteoporosis and fractures kill more people than breast cancer

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does.

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So as a primary care clinician, how can we learn to write prescriptions for hormone therapy?

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How can we learn to counsel patients properly?

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Do we have to go back and take a fellowship?

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Do I have to, how do I learn to integrate the evidence into my practice?

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So how astounding is that?

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This is a public, public paper published by Dr. Rubin talking to a fellow clinician admitting

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basically that most doctors are not well-educated to address and deal with the problems that

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menopausal women walk into their offices with every day.

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So Dr. Fabian replies, it's an easy thing to gain confidence, an easy thing to do is

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to take a course.

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The Menopause Society has this annual meeting in Chicago.

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We do a Menopause 101 course for clinicians there.

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She says, I put out my plea to primary colleagues in internal medicine and family medicine,

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you need to do this.

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Think about it.

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You're already an expert on brain health and bone health and heart health.

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You should be most comfortable in dealing with hormone therapy that has effects throughout

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the entire body.

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It's important for us as primary care providers to really have a handle on this and to be

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effectively managing menopause for women in midlife.

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Dr. Rubin replies, I couldn't agree more.

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My clinic is full of 50 something women who came back and said, sex is good.

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My relationship is good.

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I'm kicking butt at work.

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I have a patient who just started law school because she feels good, so good.

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And she says, I'm keeping up with the 20 year olds.

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It's incredible to see women who feel terrible and then watch them blossom and get better.

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Dr. Fabian replies, we know a lot of women who are missing work, not taking a promotion

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or avoiding a leadership role because of their menopausal symptoms.

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Women should never be in the position of compromising their work lives because of menopause symptoms.

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So Dr. Rubin finally says, our big takeaway is believe your patients when they've driven

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and parked and arranged childcare and showed up to your office and waited to see you when

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they're telling you they have all these symptoms and they're not feeling like themselves.

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Maybe before you jump straight to prescribing them a serotonin reuptake inhibitor Prozac

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for their depression and anxiety or just saying do some yoga and deep breathing.

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Instead of that, maybe really dive into the menopause literature and understand the pros

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and cons and the risks and benefits of hormone therapy.

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Wow.

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So these are prominent physicians interviewing, discussing this subject with one another in

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a medical paper that was just published.

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And sure, it's encouraging to see prominent physicians having discussions like this because

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hopefully many other mainstream traditional doctors will listen to them and give more

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women the care they need.

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But think about it.

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These prominent physicians are admitting in public that there's a huge gap in effective

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care that's happening for women all across the country on their watch.

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These doctors, these mainstream physicians come to these experts for their continuing

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education.

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They consult with them for difficult cases.

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And these experts are saying that most doctors aren't doing a good job with women who show

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up with multiple symptoms, all of which are often related to menopause.

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This is huge, mainly because among other reasons, apart from that horrible lack of getting the

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care that these women need is that this type of care has been available for years if you

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know where to find it.

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This is standard practice among functional medicine practitioners.

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This is a classic example of an instance where functional medicine can change someone's life

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doing comprehensive testing to identify all areas of your body where normal function has

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gone by the wayside, where support is needed and using better food, exercise, and supplements

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to restore normal function to all of your organs and tissues and systems, including

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your endocrine system that makes your hormones with safe plant-based and often very low dose

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transdermal hormone therapy can change your life or the life of someone you love.

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I'm Dr. Todd Bankley.

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You're listening to Safe, Effective Natural Solutions to Almost Any Health Challenge.

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I promised I was going to talk about a specific case of mine.

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This is a 58-year-old female who came in with overwhelming stress, fatigue, brain fog, and

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irritability, and I did a comprehensive salivary hormone test, salivary hormones.

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Instead of a blood test measuring hormones that are going up and down, up and down, all

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day long, we did an average.

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We did four, she spit, basically the test is you spit into four little tubes and it

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measures four readings of your cortisol levels, your adrenal function throughout the day,

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a half hour before you wake up, lunchtime, dinnertime, and bedtime because there's a

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natural curve in your adrenal gland activity.

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And then the lab, Doctors' Data, the preeminent lab for this type of testing in the country,

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makes a fifth tube with an average with a little bit from each of those four tubes to

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get an average throughout the day to measure your three estrogens, your progesterone, testosterone,

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and DHEA, a precursor for estrogen and testosterone.

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So anyway, this 58-year-old female's adrenal hormones were basically flatlined, just low,

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all of them were super, super low, and her estrogens were all super, super low as well.

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Her progesterone was okay, her testosterone was okay.

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So I put her on some supplements to build up her adrenal function back up and a little

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bit of estrogen support.

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Six months later, her overwhelming stress, she's still working, she's still doing her

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life, her stress is probably never going to be gone, but her stress is now tolerable,

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from overwhelming to tolerable.

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That was huge for her.

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She has dramatically less fatigue at work.

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The brain fog is gone.

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And when I asked her, what about her irritability?

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She says, well, I'm no longer irritating.

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Other people are still irritating, but my irritability is gone.

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That's the way she phrased it.

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So hormones are a huge topic.

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We're not going to get to all of it today.

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I'm going to come back and probably talk about this again next week.

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But just to close out, common symptoms of low estrogen are hot flashes, mood swings,

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anxiety, insomnia, irritability, vaginal dryness, depression, night sweats.

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Most people are familiar with those, but they may not be familiar with some of these.

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Varicose veins, urinary tract infections are symptoms of low estrogen, panic attacks, palpitations,

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flutter in the heart, loss of sexual interest, hair loss, osteoporosis, strange dreams, memory

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lapses, weight gain, hair growth on the face.

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Weight gain is always important to people.

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A lot of people don't realize that low estrogen also increases your risk of osteoporosis.

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So we're going to talk more about this next week.

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Benefits of estrogen.

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Increased metabolism helps regulate your body temperature better, prevents muscle damage,

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increases blood flow, improves sleep.

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These are benefits of estrogen.

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Decreased arterial plaque, maintain collagen in the skin, decrease blood pressure, improved

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mood, decreases bad cholesterol.

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Hormones are really important.

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Are you getting this?

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Benefits of estrogen reduce risk of heart disease, decrease wrinkles, enhanced energy, better

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bone density, increased sexual interest, better cholesterol, decreased risk of colon cancer,

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helps maintain memory.

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If you're not getting this already, hormones affect literally every part of your body.

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So who should get a saliva hormone test?

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Well, any woman who's unsatisfied, who's already on conventional hormone replacement therapy

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and is unsatisfied with the results or worried about side effects.

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Women you know who have fatigue and depression and chronic inflammation.

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Anyone that you know with heart health issues or memory loss, osteoporosis.

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And I keep talking about women because most of the people that come to me for this are

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women.

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It's mostly menopausal women that benefit the most from this.

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But men have manopause, right?

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So low testosterone affects the heart health and memory loss in men.

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And several of those other symptoms that I mentioned that you think of in women also

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affect men with low testosterone.

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And there are even normal levels of estrogen and progesterone that men need as well.

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And the only way that you know if you have enough is to get comprehensive testing.

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So we'll talk more about this next week.

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Email me your questions.

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I'd love to help someone you love get the care they need so that they can feel the way

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they should.

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Have a fantastic weekend.

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You've been listening to Safe, Effective Natural Solutions with Dr. Todd Binkley.

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If you have a health question you want discussed on the show, email your health questions to

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drbinkley at binkleyhealingcenter.com.

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Take advantage of this opportunity to ask questions for yourself and for your loved

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ones because our health matters.

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Join him next Friday at 4 p.m. for Safe, Effective Natural Solutions right here on 98.3 The Word,

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KDAR.

