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Thanks for joining. Before we get started, please make sure that you have subscribed

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and are following us on all of the various platforms that we're publishing on, whether

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here on the podcast, on YouTube, through Substack, as well as the Quick Takes being posted onto

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Instagram and onto threads. And if you're enjoying what is getting published, please

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make sure you're leaving that five star rating and sharing out with everybody that you know.

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And with that said, let's go ahead and get started. The following is an introduction

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to a section of the upcoming book, Diet Dogmas. There is a general desire to have a quick

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and simple fix that we can make to our diet that someone's going to make us, quote, lean

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and sexy, end quote, or quote, fit and healthy, end quote, a change where we can fall prey

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to quick messages, to personalities, where we almost want to follow the tenants, the

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guides, the dogmas, as if we're following a new religion. One such movement that seems

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to have taken hold over the last decade or so is the movement that we should avoid sugars

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at all costs and are constantly being told about how bad sugars are and that we need

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to get rid of sugars from our diet. Done so by following a, quote, keto diet or a, quote,

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paleo diet, or maybe even the, quote, carnivore diet. But are these the best diets for me

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to follow in order to lose weight and in order to get healthy? Well, let's talk about that.

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Warning. The following presentation contains information that might contradict what you

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have previously heard or believed to be true about how the human body works and contains

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material that is not suitable for close minded individuals. Enjoy.

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Let's go ahead and let's talk about ketogenic and paleo diets. What are the pros? What are

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the cons? What does the sign say in a quick overview? Once again, we'll be getting much

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more details within the book. And this is simply just an overview to the chapter that

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I'll shout not eat carbohydrates. So let's go ahead and let's talk about paleo and let's

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talk about keto diets. And so paleo diets, what is it? What it isn't? And should I use

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it? So what is the paleo diet? The paleo diet is a dietary philosophy that is focused on

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what we think a paleolithic human would have eaten for their diet. Based off of the idea

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that we're going to be eating a lot of raw or natural things such as fish, steak, shellfish,

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poultry, vegetables, nuts, fruits, berries, and eggs. The idea is, is that this type of

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diet is going to counteract a lot of the nutritional deficiencies that might come about through

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eating a modern diet or eating from fast food restaurants that can lead to a host of problems

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such as obesity issues, along with metabolic issues coming about through the consumption

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of various types of fast food or processed foods. But what does the evidence say? What

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is the idea that surrounds the paleo diet or the paleo diet, sometimes we're just the

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caveman diet and does it actually hold true when we start looking at the evidence? Which

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remembers that most of the recommendations that we are going to be providing from a paleo

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diet is coming from analysis of modern hunter and gatherer associations, hunter and gatherer

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groups, not necessarily what might have been consumed during paleolithic time. We also

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have to remember that a lot of the foods that we're going to consider to be paleo are actually

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modern in their derivations. A lot of the benefits that we're going to look at are not

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universal and there is some question as to whether or not the benefits that we see coming

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from the diets are coming from the diet or coming from other things. So what do we know

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that comes out in terms of benefits? We do know that there is some benefits that come

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about from following a paleolithic dietary practice or paleo diet or a caveman diet.

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A lot of these benefits are similar to the benefits that we see coming from things like

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intermittent fasting, a very low carbohydrate diet, as well as with a plant rich diet, things

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like increased insulin sensitivity and neuroplasticity within the nervous system and a reduction

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in ROS gamut, an increase in metabolic flexibility and increase in insulin sensitivity and increase

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in lipolysis, breakdown of lipids and an increase in an anabolism, growing of tissues within

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the musculoskeletal system. Within the cardiovascular system, this is where we start seeing a lot

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of differences that might come about where we don't see universally one direction in

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terms of changes, where we will see a change in compliance, a change in cardiac function,

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a change in atherosclerosis and a change in inflammation that is highly questionable in

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terms of its root benefit coming from the diet as opposed to other lifestyle changes.

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In adipose tissue, we do see an increase in insulin sensitivity, an increase in lipolysis,

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the breakdown of lipids, as well as a change in adipokine signaling and macrophage signaling.

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Changes in adipokine signaling changes in the hormone signals coming from the adipose

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tissue as well as changes in macrophage activation lead to changes in inflammation that may lead

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to the reduction in ROS damage and the reduction in inflammation that we see throughout the

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body for people who follow a Paleolithic diet. In terms of pancreas functions, we do see

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a normalization of insulin and glutagon levels for those individuals who happen to have metabolic

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issues, metabolic syndrome or type 2 diabetes that follow a Paleo diet. But once again,

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it is not universal and may be associated with changes in activity as well as other

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lifestyle intervention. In terms of liver functions, once again, we do see some questionable

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responses coming out of liver functions. However, for those who follow a Paleo diet that has

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the reduction in or reduces the consumption of a lot of the sugars and a lot of the grains,

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we will see an increase in ketone formation due to a change in metabolic functions towards

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lipid utilization and ketogenic processes. As with all the other insulin sensitive tissues,

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we will see an increase in insulin sensitivity due to the reduction in sugar loads and in

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carbohydrate loads. We will see an increase in ROS clearance as well as a change in the

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non-alcoholic fatty acid liver issues within the liver for people who have metabolic issues

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and change diet to follow a Paleo diet. Well, that's all well and good. What about the entirety

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of the research? We did say that there was some questionable and some responses that

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were not universally found. And so the question comes about is, does it automatically mean

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a healthier food in our diet? Is our diet automatically healthier because we are going

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to be eating more unprocessed foods, at least that's the claim, or eating things that are

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more in line with what we would have had in Paleolithic times, closer to what some people

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refer to as ancestral human diets. The problem is that a lot of the claims about ancestral

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human diet is going to ignore a lot of the evolutionary processes that have happened

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within human history. And so if we look at a lot of the evidences out there, is it actually

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safer? Do we actually have evidence to show that the Paleo diet is worth all of the hype

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that we tend to attribute to it? And this is where once again, just like with all the

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other diets, we have to go back and say, well, we're going to have deficiencies and we're

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going to have deficiencies because we're going to be cutting out things from the diet.

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Based off of how we go about setting up the Paleo diet, we could be deficient in various

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vitamins such as vitamin B, in particular folate, as well as vitamin C and vitamin D,

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as well as some other antioxidants. We could have ion deficiencies, ion deficiencies such

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as calcium, iron, iodine, magnesium, psyllium and sodium. Notice there's a question mark

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on the sodium deficiency and that depends upon what type of meats we're going to be

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eating and how we go about seasoning the meats. However, with the reduction in dairy consumption,

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we do run the risk of having calcium deficiency as well as vitamin D deficiency. With the

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reduction in grain consumption, we do risk having vitamin B deficiencies coming about

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in particular the folate, but also with the niacin. We will also see a change in psychological

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drive for food more in a Paleo diet than in many of the other diets simply because of

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the excessive labeling of good food versus bad food. Because of the lower consumption

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of vegetables in some of the diets, this is going to be very similar to what we see with

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a very low carbohydrate ketogenic diet, we do run the risk of diet induced metabolic

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acidosis. The other thing that to worry about based off of the type of foods that we're

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eating in terms of getting our proteins, our fats and our carbohydrates is an excessive

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load of animal saturated fat, animal antigens and cholesterol issues. The animal antigen

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and cholesterol issues can lead to an actual increase in atherosclerosis, hardening of

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the arteries as well as cardiovascular disease. Based off of the type of animals that we're

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going to be eating within the Paleo diet, we could see a hyper saturation of saturated

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fats, meaning we're going to have large amounts of saturated fats relative to our polyunsaturated

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fats or MUFAs and our monounsaturated fats or MUFAs. Based off of the source of the animal

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protein, we could see altered fat metabolism and fat absorption taking place as well as

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altered cholesterol metabolism within the liver, which could lead to increased levels

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of circulating LDLs within the body. So one of the things we have to address within

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the idea about the Paleo diet is, is it actually truly close to the Paleolithic diet? That

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is, is it actually historically close to what we would think of as a Paleolithic diet? And

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once again, what we're looking at is we're looking at dietary practices that are closer

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to hunter gatherer practices than actual Paleolithic practices, mainly because the foods that we're

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eating have evolved with us evolving. The other thing is that a lot of the ideas around

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the Paleolithic diet kind of goes to the, to the GIF at the very beginning of the discussion

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in terms of the Flintstones is that we misrepresent what actually is historically accurate in

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terms of our dietary practices, 10, 20, 30, 40,000 years ago. As we were doing a lot of

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cultivating, we're doing a lot of agricultural cultivation and domestication taking place,

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which means a lot of the foods that we think about as being modern aren't actually modern,

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they're more Paleolithic than we actually attribute in terms of their sourcing. But

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the other thing is, is that just like with all other diets, we start having mass produced

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issues. We start having things that are becoming processed, things that are having chemical

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additives within it, things that can and do act like metabolic disruptors, which means

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that we run the risk of having metabolic disruption taking place from following a Paleo diet,

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very similar to following a lot of the other diets that we think about as having health

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benefits to it based off of the way in which it's being sold to us. And so if we start

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looking at the underlying issues coming into the Paleolithic diet, it's not as clear cut

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as what we would hope it would be based off of how the chemicals and how the nutrients

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and how all of the processing takes place, particularly for the mass produced Paleo labeled

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foods. If we're to follow a Paleo diet based off of the use of meats and vegetables and

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nuts and berries and fruits without purchasing the mass produced foods, we will lower the

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risk of having metabolic disruption within there, based off of the percentages that we

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see in terms of consumption, where there is a wide range in what is being advertised or

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advised in terms of consumption of macronutrient, we could still have metabolic disruption taking

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place based off of following a Paleo diet. One such type of diet that we might have is

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that keto diet, where we're going to skip the carbs, eat the fat, eat the protein, stuff

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that has become very popular. So what is the ketogenic diet? The ketogenic diet is a

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diet that is meant to eliminate a lot of the sugars and starches and replace them with

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fats and proteins. Depending upon what type of ketogenic diet you might follow, you'll

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see a different type of breakdown in terms of fats versus protein. But the idea here

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is to by eliminating a lot of the sugars and by eliminating a lot of the fast foods that

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we might consume within our diet, we're able to eliminate a lot of the metabolic diseases

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that are facing us currently, a lot of the over fatness and hyperadiposity that affects

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us both aesthetically as well as metabolically, as well as in terms of our health. And so

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what's the evidence say? What do we know about ketogenic diet that is going to lead to some

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of the health benefits that get reported as relates to the ketogenic diet? Well, a lot

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of it has to do with changes in metabolism based off of changes in our energy utilization,

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where we're going to change the fuel sources that we're going to follow to get the ATP

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within the body, where instead of using a lot of carbohydrates, while we will still

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use some carbohydrate, the majority of energy metabolism is going to focus on fat utilization

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through most of the activities that we're going to have. By changing the use of sugars

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to use of fats, we're going to change a lot of hormone actions that might take place.

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Some actions that will lead to changes in various types of sensitivity, as well as various

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types of masses that we might see within the body, as it's going to change our relative

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body compositional ratio. Within our adipose tissue, because we're going to change our

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dietary practices, we're going to end up increasing the utilization of fat and increasing hormone

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changes that will increase the amount of fat breakdown we might see within adipose tissue.

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This is going to be accompanied by a change in insulin sensitivity, a change in hormone

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signaling, and a change in macrophage signaling from the macrophages from the immune cells

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that we see within the fat masses of the body. Changes in metabolism at the fat cells is

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going to lead to changes in hormone signaling coming away from the pancreas, which is going

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to lead to normalization of insulin and glucagon, particularly for people who have insulin and

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glucagon issues, metabolic issues, due to overfatness. At the liver, we're going to

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see an increase in gluconeogenesis, making of glucose from glucose metabolites, as well

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as an increase in ketone formation due to the restriction that we might have in total

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amount of carbohydrates that we're going to consume. What we have to remember is that

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we need 120 grams of carbohydrates minimum in order to have proper neuron function. And

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in order to meet that glucose need, the liver is going to produce more glucose for the body

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through gluconeogenesis. Because of the change in fat metabolism, we will see an increase

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in insulin sensitivity is going to come about due to changes in normalization of insulin

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and glucagon signaling, as well as an increase in ROS clearance due to changes in metabolism

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is going to reduce the total amount of ROS that we might see within the body due to changes

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in inflammation. In the nervous system, we're going to see changes in insulin sensitivity

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that's going to lead to neuroplasticity. The changes in insulin sensitivity, along with

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a reduction in ROS inflammation damage has been attributed to the changes that we might

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see within neurodegenerative diseases for people who follow a ketogenic diet. There

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is some reported benefit for people who have seizure disorders, where following a ketogenic

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diet will reduce the total number of seizures and the total level of seizure that might

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be experienced if one would one would experience a seizure. Within the musculoskeletal system,

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we will see various changes in metabolic flexibility, we will change what fuel sources we might

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use for energy purposes. We will see an increase in insulin sensitivity, we will see a change

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in fat mass utilization, fat mass utilization for energy purposes, which means we're going

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to see an increase in lipolysis and fatty acid oxidation. We may see an increase in

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protein utilization. However, that increase in protein utilization for energy purposes

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will be offset by increase in anabolic responses, growth responses, as well as the retention

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of skeletal mass and skeletal muscle mass that is bone and skeletal muscle tissue being

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retained during weight loss period. In terms of cardiovascular benefit, this is where we

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see a lot of variability based off of how we measure changes within the systems based

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off of the ketogenic diet. Where due to a reduction in inflammation, we may see changes

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in atherosclerosis and change in cardiac functions. However, this is not universally seen for

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everybody following a ketogenic diet based off of the ability to metabolize fats within

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the body. So all that sounds great, but then we got to think, wait, is it too good to be

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true? Is it a panacea? Is it something that is going to be a cure all? This is where we

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have to start looking at what does the evidence say? Just eating keto doesn't mean being healthier.

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There is some indication that following a high fat diet can hurt exercise performance

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and can hurt athletic performance. But how true is that? Well, if we look into the research,

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there is some evidence to support that eating keto is not necessarily automatically healthier

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and following a high fat diet may impact my exercise performance, particularly in explosive

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exercises as well as in long duration exercises, which is interesting given the fact that when

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we do long duration exercise or long duration activities, we tend to utilize more fats than

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we do carbohydrates. But the problem is, is that changes in fat utilization following

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a ketogenic diet may lead to a reduction in explosive muscle contraction capability because

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of the reduction in glycogen and glycogen stores within the muscles. So what else might

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we have to worry about as it relates to ketogenic diet deficiencies? Just like with any other

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diet that we might follow, if we are not eating what we should be eating, we have to worry

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about micronutrient deficiencies and macronutrient deficiencies. In this case here, because of

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the restriction on types of foods that we might be eating, people who follow a ketogenic

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diet that do not eat large amounts of vegetables, in particular, low glycemic vegetables may

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have fiber deficiencies because of the increased use of fat or fuel source. People who follow

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a ketogenic diet may have a carnitine deficiency. There is some evidence to support due to metabolic

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use, vitamin B deficiencies. Once again, because of the type of foods that are being consumed,

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we might have a vitamin C deficiency. Along with deficiencies in vitamins and in some

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of our amino acids and some of our protein sources, we will also see some cation electrolyte

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deficiency. There is some evidence to support that we might have a deficiency in iron, might

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see a deficiency in magnesium and selenium, might see a deficiency in potassium and sodium

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based off of following a ketogenic diet. Now, a lot of people might say, well, I'm going

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to be eating large amounts of meat, so why am I going to have an iron deficiency when

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we know that people who eat animal protein will automatically have higher amounts of

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iron in their diet relative to people who don't eat animal protein? Well, based off

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of the foods that we're eating following a ketogenic diet, we may have competition for

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transport of a lot of these cations. At the same time, because I'm not consuming large

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amounts of starches and large amounts of sugars, I do not have the ability to absorb a lot

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of these cations due to current flow across the membranes of the intestine. A lot of the

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ions that we see listed here are moving with water and water movement. It goes hand in

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hand, particularly with sodium, as well as with a lot of the starches that we might have,

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carbohydrates that we might have within our diet, where if I restrict the carbohydrates,

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I may also restrict the movement of these cations. Because of the implicit and explicit

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good food versus bad food idea, there is a change in psychological drive for foods that

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may lead to various types of food cravings, but there's also a lot of social exclusion

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going on within the ketogenic diet. The good food, bad food, and the social exclusion leads

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to a very restrictive diet that can cause social exclusionary behaviors to take place

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that may limit the likelihood of following the diet for long periods of time. There is

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a chance based off of how we establish the ketogenic diet to induce a metabolic acidosis

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within the person who follows the ketogenic diet due to the large amounts of animal protein

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or protein in general, as well as the amount of fat within the diet. Speaking of fat, the

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higher amounts of saturated fat and lower amounts of polyunsaturated fat and monounsaturated

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fat, as well as an imbalance in the ratio between all the saturated fat and monounsaturated

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fat, as well as the ratio in between our omegas, omega threes and omega sixes, can lead to

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an altered fat absorption and metabolism taking place within the body. For some people, because

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of genetic issues, they may have an altered ability to metabolize the cholesterol that's

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being consumed, which may lead to an increase in LDL levels for individuals who are trying

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to follow the ketogenic diet. Along with that, we might also have issues that come about

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because of the fact that just because I am following a ketogenic diet, we tend to think

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of the fact that we're following a natural food consumption. What we have to remember

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is that a lot of these foods are going to be mass produced foods. And a lot of times

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we're going to be consuming a lot of non-nutritive sweeteners. Non-nutritive sweeteners have

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recently come into having a negative ideal about them as relates to increased risk for

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cancer, increases for cardiovascular disease, increased risk for homeostasis as relates

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to body weight issues and glucose metabolism, where the over consumption of a lot of these

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non-nutritive sweeteners can act like metabolic disruptor. Now we have to have a caveat on

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this because a lot of the evidence that we have is within animal models that do not in

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100% way correlate with humans in terms of how we physiologically function and metabolically

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function. However, over consumption of artificial sweeteners, non-nutritive sweeteners has been

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linked with increased food intake, has been linked with abnormal insulin secretions, has

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been linked with cardiovascular disease, has been linked with abnormal growth signals within

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skeletal muscles, all mimicking what we might have already seen with people who exhibit

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metabolic syndrome and over fatness, even though we're consuming these non-nutritive

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sweeteners in an attempt to reduce caloric intake. And once again indicates that changes

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in nutrition and changes in diet as relates to body weight, body composition and overall

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health is not about calories. It's about the nutrients that are being consumed. Along with

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this non-nutritive sweeteners tend to taste sweeter than normal sugar in terms of their

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level of sweetness and our bliss point, which may lead to an over consumption of food in

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an attempt to get the bliss point of consumption that we are attempting to get from food consumption,

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which may lead to an increase in nutrient balance towards the consumption side that

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can lead to increase in fat mass that we are attempting to combat by following the ketogenic

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diet.

