1 00:00:00,000 --> 00:00:02,500 Welcome to the, your mom on drugs podcast. 2 00:00:02,540 --> 00:00:07,500 You've got me, Josh Klaus, the son and the mom, Jennifer Seltzer. 3 00:00:07,980 --> 00:00:08,940 Hi everybody. 4 00:00:09,580 --> 00:00:09,900 Yeah. 5 00:00:09,940 --> 00:00:13,640 Uh, this is a podcast basically about drugs. 6 00:00:13,640 --> 00:00:18,080 Um, usually the kind that you take over the counter, um, or the ones prescribed 7 00:00:18,080 --> 00:00:22,420 to you by your medical professional, um, or by your local pharmacist. 8 00:00:22,820 --> 00:00:26,460 And, uh, we just thought it would be a really good idea just to talk about, you 9 00:00:26,460 --> 00:00:29,940 know, when you put something into your body, like what's actually going on. 10 00:00:29,940 --> 00:00:32,940 And one of the best times to put that thing into your body. 11 00:00:33,500 --> 00:00:39,780 Um, and so we just wanted my mom is a doctor of pharmacy and she always gave 12 00:00:39,780 --> 00:00:41,300 me a great pharmaceutical advice. 13 00:00:41,300 --> 00:00:44,920 And so I always thought it'd be a really great idea, uh, to share 14 00:00:44,920 --> 00:00:46,820 her knowledge, uh, with the world. 15 00:00:47,140 --> 00:00:51,220 And so here we are sharing the knowledge, uh, with the world, and we 16 00:00:51,220 --> 00:00:52,700 hope that you find it useful. 17 00:00:52,700 --> 00:00:57,220 Um, and today we're going to be talking about allergies, which is a huge topic. 18 00:00:57,220 --> 00:00:58,140 It's very broad. 19 00:00:58,860 --> 00:01:04,180 We're going to be talking about a couple of specific, um, allergic conditions. 20 00:01:04,460 --> 00:01:07,340 Um, but we're going to give a broad overview first. 21 00:01:07,340 --> 00:01:11,580 And so I'm going to turn it over, uh, to my dear mother, who's going to kind 22 00:01:11,580 --> 00:01:13,340 of give an overview of allergies. 23 00:01:13,340 --> 00:01:17,980 So mom, if you had to describe allergies to someone on the street, someone like 24 00:01:17,980 --> 00:01:20,540 me, how would you describe allergies? 25 00:01:20,540 --> 00:01:28,980 I think just generally a person needs to realize that an allergy is a particular 26 00:01:29,380 --> 00:01:34,580 person or their body's response to something that's normally considered harmless. 27 00:01:35,220 --> 00:01:39,340 So, and we don't necessarily know initially to expect that we're going 28 00:01:39,340 --> 00:01:41,420 to have an allergic reaction to something. 29 00:01:41,780 --> 00:01:48,980 I mean, it's an exaggerated immune response to something that's kind of benign. 30 00:01:48,980 --> 00:01:54,300 Um, and it's an, actually, I thought this was really interesting as I did my research. 31 00:01:54,620 --> 00:01:57,020 It's really the immune response. 32 00:01:57,020 --> 00:02:03,500 It's our body's response to that and what we call an antigen or the allergen, but 33 00:02:03,500 --> 00:02:07,420 it's not the actual allergen that's harmful to the person. 34 00:02:07,980 --> 00:02:08,660 Oh, okay. 35 00:02:08,660 --> 00:02:15,260 So, so I know a lot of people complain of things like pet dander or in here in Texas, 36 00:02:15,260 --> 00:02:19,100 we have Cedar fever, which is something that people really complain about. 37 00:02:19,580 --> 00:02:24,180 Um, so it's not the actual thing that you're breathing in or touching 38 00:02:24,180 --> 00:02:25,540 that's causing the problem. 39 00:02:25,660 --> 00:02:26,540 It's something else. 40 00:02:26,780 --> 00:02:27,300 It's right. 41 00:02:27,300 --> 00:02:29,540 It's your body's response to it. 42 00:02:30,220 --> 00:02:30,700 Okay. 43 00:02:30,740 --> 00:02:31,300 Okay. 44 00:02:31,460 --> 00:02:35,900 I wish I thought that was really interesting because if you have known anyone 45 00:02:35,900 --> 00:02:40,740 that's had an allergy to something and you talk to several people, their 46 00:02:40,780 --> 00:02:43,220 symptoms can be varied, you know. 47 00:02:43,220 --> 00:02:48,740 Based on the way that their body is responding to that particular antigen or allergen. 48 00:02:48,940 --> 00:02:49,460 Gotcha. 49 00:02:49,460 --> 00:02:54,060 And a couple of episodes before we've talked about things like the common cold, 50 00:02:54,060 --> 00:02:58,900 and we've talked about conjunctivitis AKA pink guy, and these are things 51 00:02:58,900 --> 00:03:05,620 caused by things like bacteria and viruses, which normally when someone is 52 00:03:05,620 --> 00:03:11,020 infected with a virus or a bacteria, it usually affects the same type of, I 53 00:03:11,020 --> 00:03:15,460 would say most people in a similar way, like for someone to get a common cold. 54 00:03:15,940 --> 00:03:19,460 She's going to affect people in a similar way, but not everyone who 55 00:03:19,460 --> 00:03:23,740 breathes in pet dander is going to get a severe allergic reaction. 56 00:03:23,860 --> 00:03:24,620 Absolutely right. 57 00:03:24,620 --> 00:03:28,380 It's going to be dependent on a couple of things in your own body that are 58 00:03:28,380 --> 00:03:30,500 going to be responsible for this reaction. 59 00:03:30,700 --> 00:03:32,180 Yes, that is true. 60 00:03:32,420 --> 00:03:37,900 So, um, what are some of the things that are going on inside of your body? 61 00:03:37,900 --> 00:03:41,420 Um, I, I, I remember reading too, I think that there are a couple of 62 00:03:41,420 --> 00:03:44,340 different types of, of allergic reactions. 63 00:03:44,340 --> 00:03:51,420 I remember there's one that's associated with this, um, this chemical called IgE. 64 00:03:51,660 --> 00:03:56,820 Um, and that stands for immunoglobulin, which is, uh, essentially it's an 65 00:03:56,820 --> 00:04:02,820 immune mediator, um, it is globulin kind of, if you can picture something 66 00:04:02,820 --> 00:04:07,740 almost like a globe and immunosending for, uh, you know, the immune system. 67 00:04:08,340 --> 00:04:11,940 And then there are many different types of these, and this happens to be type E. 68 00:04:12,260 --> 00:04:15,340 Um, you've also got IgG running around IgA. 69 00:04:15,580 --> 00:04:16,580 There's IgA. 70 00:04:17,060 --> 00:04:18,460 Um, IgM. 71 00:04:18,460 --> 00:04:22,140 I don't know how they name these things, but they got their names. 72 00:04:22,300 --> 00:04:28,180 And, um, so IgG IgE is associated with allergic reactions. 73 00:04:28,180 --> 00:04:30,380 And there's also other types of IgE. 74 00:04:30,380 --> 00:04:34,100 And those are things like, um, topical, uh, dermatitis. 75 00:04:34,140 --> 00:04:37,500 So like things like poison ivy, like you actually don't get a lot of 76 00:04:37,500 --> 00:04:39,740 IgE released in those reactions. 77 00:04:39,980 --> 00:04:43,940 So I think today we're going to probably focus on things happening with IgE, 78 00:04:43,980 --> 00:04:48,020 the stuff that happens inside of your body rather than on the top of your skin. 79 00:04:48,420 --> 00:04:51,740 Um, so mom, you want to fill in any more information? 80 00:04:51,740 --> 00:04:54,300 I'm going to, I'm going to try to like briefly cut out the 81 00:04:54,300 --> 00:04:56,220 things that are happening inside of your body. 82 00:04:56,220 --> 00:04:58,700 So I'm going to, I'm going to try to, I'm going to try to, I'm going to 83 00:04:58,700 --> 00:05:02,780 try to like briefly cover, you know, all the different types of allergic 84 00:05:02,780 --> 00:05:07,180 reactions that can happen, but we're really going to focus more on what we 85 00:05:07,180 --> 00:05:13,700 label, um, immediate hypersensitivity reactions or allergic reactions and 86 00:05:13,700 --> 00:05:16,380 delayed hypersensitivity reactions. 87 00:05:16,420 --> 00:05:16,620 Yeah. 88 00:05:16,620 --> 00:05:20,460 So something can happen right away or it can happen a few days later, 89 00:05:20,500 --> 00:05:21,940 hours to a few days later. 90 00:05:22,420 --> 00:05:22,780 Yeah. 91 00:05:23,220 --> 00:05:28,380 So let me just kind of dive in a little bit as far as kind of how an allergy 92 00:05:28,380 --> 00:05:29,220 can happen. 93 00:05:29,820 --> 00:05:37,540 Um, when, when your body comes into contact with what we call the allergen 94 00:05:37,540 --> 00:05:39,980 or we call it the antigen as well too. 95 00:05:39,980 --> 00:05:42,940 So it's going to be the thing that comes into your body that maybe 96 00:05:42,940 --> 00:05:49,540 your body has not seen before it can sensitize or prime your immune system 97 00:05:49,580 --> 00:05:54,540 because it's your immune system that is going to give you the response if 98 00:05:54,540 --> 00:05:56,660 you're going to have an allergic reaction. 99 00:05:56,660 --> 00:06:03,660 So then if you get exposed to that same allergen or antigen again, that's 100 00:06:03,660 --> 00:06:06,460 when you're going to see the allergic reaction. 101 00:06:07,100 --> 00:06:13,100 Um, so sometimes it may happen in seconds, minutes to hours, where other 102 00:06:13,100 --> 00:06:17,060 times it could take hours to days to see that reaction. 103 00:06:17,820 --> 00:06:22,540 Um, the one that when we see that immediate reaction, as Josh was 104 00:06:22,540 --> 00:06:28,340 talking about is usually the one that has IgE, um, that we see those levels raised. 105 00:06:28,660 --> 00:06:31,540 They can be your anaphylactic reactions too. 106 00:06:32,260 --> 00:06:36,540 Um, you know, where you, you know, they can sometimes be life threatening 107 00:06:36,540 --> 00:06:38,460 and we'll get into that in just a minute. 108 00:06:38,860 --> 00:06:46,620 Um, and, um, so what happens is that IgE will bind to things in your immune 109 00:06:46,620 --> 00:06:50,460 system called mast cells and basophils. 110 00:06:50,460 --> 00:06:55,860 And they will release what we call mediators such as things like histamine. 111 00:06:55,860 --> 00:06:58,380 Everybody's heard of histamine or antihistamines. 112 00:06:58,620 --> 00:07:01,300 And so when you get a bunch of histamine released, then you can 113 00:07:01,300 --> 00:07:03,060 start having some symptoms. 114 00:07:03,980 --> 00:07:04,140 Yeah. 115 00:07:04,140 --> 00:07:07,980 And some of those symptoms as people who maybe have experienced an allergic 116 00:07:07,980 --> 00:07:13,420 reaction before is that you can get some vasodilation, which means more blood 117 00:07:13,420 --> 00:07:16,460 rushing to an area, which means it kind of means like swelling. 118 00:07:16,460 --> 00:07:18,780 So you might feel some uncomfortable pressure. 119 00:07:18,780 --> 00:07:22,420 Or you might get some bronchoconstriction, which makes it a little bit harder to 120 00:07:22,420 --> 00:07:22,980 breathe. 121 00:07:23,620 --> 00:07:27,740 Um, also some mucus production being increased as well. 122 00:07:27,780 --> 00:07:28,140 Right. 123 00:07:28,180 --> 00:07:31,860 Runny nose and, um, redness, you know, and stuff. 124 00:07:31,860 --> 00:07:35,100 And I know y'all worth, we're throwing a lot of information out there and we just 125 00:07:35,100 --> 00:07:38,940 want to let you know that, you know, this is to our best understanding and to any 126 00:07:38,940 --> 00:07:42,260 scientists best understanding, this is not a definitive answer. 127 00:07:42,740 --> 00:07:46,340 Um, you know, basically the immune system is very complicated. 128 00:07:46,340 --> 00:07:51,460 Imagine when let's imagine you're ordering something on Amazon and you 129 00:07:51,460 --> 00:07:55,340 click, I want to buy this toothbrush and you click buying the toothbrush and all 130 00:07:55,340 --> 00:07:56,860 of a sudden the toothbrush appears. 131 00:07:57,380 --> 00:08:01,780 Do you think the only two steps involved for you clicking that button and then 132 00:08:01,780 --> 00:08:02,860 toothbrush appearing? 133 00:08:03,180 --> 00:08:04,100 Absolutely not. 134 00:08:04,420 --> 00:08:07,780 There's tons of stuff happening behind the scenes that you're probably 135 00:08:07,780 --> 00:08:11,300 unaware of the person driving to work, the person going to pick up the 136 00:08:11,300 --> 00:08:14,660 toothbrush from the bin, the person putting that toothbrush in the bin. 137 00:08:14,660 --> 00:08:17,500 The person putting that toothbrush in the truck, et cetera. 138 00:08:17,700 --> 00:08:18,460 You know what I mean? 139 00:08:18,900 --> 00:08:28,020 So anytime you have a stimulus, AKA the, the allergen and the response, which is 140 00:08:28,020 --> 00:08:33,900 feeling the allergic reaction, there might be one, two, or hundreds of steps 141 00:08:34,140 --> 00:08:35,700 that happen in between. 142 00:08:36,420 --> 00:08:40,380 And sometimes understanding those steps is really important to understand what 143 00:08:40,380 --> 00:08:44,420 type of therapy you might need, whether it's pharmaceutical, whether it's life 144 00:08:44,420 --> 00:08:48,140 style change, whether it's even something in your house, such as like a better 145 00:08:48,140 --> 00:08:50,740 filter to filter out more antigens. 146 00:08:51,500 --> 00:08:54,820 Because mom, I was going to say like, you know, I've been hanging around 147 00:08:54,820 --> 00:08:58,380 pets all my life and I've never gotten a pet allergy. 148 00:08:58,580 --> 00:09:03,220 So it seems to be that certain people, maybe with elevated IgE levels, just 149 00:09:03,220 --> 00:09:07,260 due to genetics or sometimes even bad luck, like sometimes this cascade can 150 00:09:07,260 --> 00:09:11,620 just be triggered and they can get allergic reactions, correct? 151 00:09:11,740 --> 00:09:12,260 Right. 152 00:09:12,820 --> 00:09:13,540 That's right. 153 00:09:13,540 --> 00:09:15,180 So there's something really interesting. 154 00:09:15,180 --> 00:09:17,980 Sorry to, I'm then I'm going to let my mom continue on. 155 00:09:17,980 --> 00:09:23,940 There's something out there called the hygiene hypothesis, which is, um, as 156 00:09:24,460 --> 00:09:30,380 countries, especially in the West places like Britain, Denmark, the US, et cetera, 157 00:09:31,020 --> 00:09:36,580 as we've gotten cleaner and richer, we've basically removed ourselves from the 158 00:09:36,580 --> 00:09:41,700 outside world that we've cohabited with for, you know, tens of thousands of years. 159 00:09:41,700 --> 00:09:46,140 And things like parasites and different bacteria that normally live in our 160 00:09:46,140 --> 00:09:47,820 body don't live in our body anymore. 161 00:09:47,860 --> 00:09:51,060 So our immune system isn't used to fighting something off. 162 00:09:51,940 --> 00:09:56,220 And so in absence of that, instead of twiddling its thumbs, it's thinking, 163 00:09:56,220 --> 00:09:57,500 well, what can I attack? 164 00:09:57,540 --> 00:10:02,940 And it basically attacks things like peanuts or the, or it's something like 165 00:10:02,940 --> 00:10:07,140 pet dander, things that are normally harmless in an environment, but in such 166 00:10:07,140 --> 00:10:11,540 a clean, pristine environment, your immune system is not going to be 167 00:10:11,540 --> 00:10:13,100 able to do anything to protect you. 168 00:10:13,100 --> 00:10:17,420 And so you're going to have to be able to do something to protect yourself. 169 00:10:17,420 --> 00:10:23,060 And so, and I think that's a really good example of how our immune system 170 00:10:23,060 --> 00:10:27,220 isn't smart enough to say, oh, that's foreign or that's good. 171 00:10:27,580 --> 00:10:29,860 It is literally just ready and prime to go. 172 00:10:30,140 --> 00:10:35,340 So there's actually current literature out there that actually exposing kids 173 00:10:35,380 --> 00:10:41,260 or young, you know, young people to a various array of, of substances that are 174 00:10:41,260 --> 00:10:42,220 into your adulthood. 175 00:10:42,660 --> 00:10:43,820 So I just wanted to put that out there. 176 00:10:43,820 --> 00:10:46,420 The hygiene hypothesis is a really interesting one. 177 00:10:47,220 --> 00:10:50,820 The idea that we've just become a little too clean, but there's 178 00:10:50,820 --> 00:10:51,820 trade-offs for everything. 179 00:10:51,820 --> 00:10:58,140 Cause we also don't have to deal with river blindness or dengue fever, for example. 180 00:10:58,380 --> 00:11:04,300 So I would much rather trade dengue fever for maybe some hay fever, if that's the 181 00:11:04,300 --> 00:11:06,180 case, but I also don't have to deal with hay fever. 182 00:11:06,220 --> 00:11:08,060 So maybe I'm speaking in a turn. 183 00:11:08,060 --> 00:11:10,380 Sorry for anybody out there who's dealing with hay fever. 184 00:11:10,380 --> 00:11:12,660 So enough with me talking. 185 00:11:12,660 --> 00:11:13,860 So mom, would you continue on? 186 00:11:13,860 --> 00:11:17,820 You were talking about mass cells and histamine and being released in your body. 187 00:11:17,820 --> 00:11:18,060 Right. 188 00:11:18,060 --> 00:11:21,860 And that was really part of what we call the immediate or sometimes the 189 00:11:21,900 --> 00:11:24,300 anaphylactic allergic reaction. 190 00:11:24,660 --> 00:11:29,300 There's also a delayed allergic or hypersensitivity reaction. 191 00:11:29,540 --> 00:11:32,780 And that is really T cell mediated. 192 00:11:32,780 --> 00:11:35,780 We have T cells inside of our immune system as well. 193 00:11:35,780 --> 00:11:41,100 And they are going to activate what we call interleukins, which are really 194 00:11:41,100 --> 00:11:44,780 powerful mediators of an allergic response. 195 00:11:45,100 --> 00:11:48,900 And so again, we had the IgE with an immediate allergic reaction. 196 00:11:48,900 --> 00:11:52,740 We've got T cells and a delayed reaction and it just takes them a little 197 00:11:52,740 --> 00:11:54,300 bit longer to get activated. 198 00:11:54,500 --> 00:11:58,660 That's why it can be hours to days before you see an allergic reaction with 199 00:11:58,660 --> 00:12:01,140 a T cell mediated allergic reaction. 200 00:12:01,460 --> 00:12:01,660 Yeah. 201 00:12:01,660 --> 00:12:05,140 Just to give you an idea, T cells are actually cells. 202 00:12:05,140 --> 00:12:09,540 And so they're much larger than IgE, which is just a protein. 203 00:12:09,980 --> 00:12:13,900 So sometimes it just takes a longer time for that T cell to move to where 204 00:12:13,900 --> 00:12:16,420 it needs to go, just due to physics and size. 205 00:12:16,540 --> 00:12:17,060 Yes. 206 00:12:17,260 --> 00:12:23,860 And so just let me give you two other, just for completeness, let me give you 207 00:12:23,860 --> 00:12:31,500 two other types of hypersensitivity or allergic reactions, but we're not 208 00:12:31,500 --> 00:12:33,540 going to spend a lot of time on these. 209 00:12:33,540 --> 00:12:37,380 One is called cytotoxic hypersensitivity. 210 00:12:37,660 --> 00:12:43,820 And this occurs when the antibody directed at those antigens or allergens 211 00:12:43,860 --> 00:12:48,500 of the cell membrane, they act activate our compliment system. 212 00:12:48,740 --> 00:12:53,260 And so this is going to cause a, it's called what a, a membrane attack 213 00:12:53,260 --> 00:12:57,220 complex, or it's kind of like cytotoxicity where the cells are kind of 214 00:12:57,220 --> 00:12:59,380 attacking, you know, the body and stuff. 215 00:12:59,380 --> 00:13:02,500 So, um, and they'll literally attack their own tissue. 216 00:13:02,580 --> 00:13:02,980 Right. 217 00:13:02,980 --> 00:13:03,580 Right. 218 00:13:03,620 --> 00:13:09,020 And so, I mean, you can see this in some drug, um, allergic reactions, 219 00:13:09,060 --> 00:13:14,860 and you can also see it too in some, uh, if there's some things happen, um, when 220 00:13:14,860 --> 00:13:20,020 you get certain infections, like, um, you could get hemolytic anemia and that, 221 00:13:20,340 --> 00:13:22,460 that you can get hemolytic anemia. 222 00:13:22,460 --> 00:13:27,060 And, um, and that would be due to this cytotoxic hypersensitivity. 223 00:13:27,260 --> 00:13:29,260 We're not going to spend a lot of time on that though. 224 00:13:29,940 --> 00:13:30,220 Yes. 225 00:13:30,220 --> 00:13:31,300 And you said there was one more. 226 00:13:31,300 --> 00:13:35,020 One more is called immune complex hypersensitivity. 227 00:13:35,420 --> 00:13:40,460 And this is when that antigen antibody complex causes an 228 00:13:40,460 --> 00:13:42,740 inflammatory response in tissues. 229 00:13:43,060 --> 00:13:49,860 So the difference between that cytotoxic, um, hypersensitivity reaction and this 230 00:13:49,860 --> 00:13:58,540 immune complex cytotoxic, um, uh, hypersensitivity reaction is that with the first one, 231 00:13:58,540 --> 00:14:03,660 the, the allergen is bound to a part of the cellular membrane. 232 00:14:04,180 --> 00:14:08,700 Um, but in the type three, I mean, I'm sorry, but within the immune complex 233 00:14:08,700 --> 00:14:13,580 hypersensitivity reaction, the, the allergens are freely circulating. 234 00:14:13,580 --> 00:14:18,740 So they can go, you know, in different places and that particular type of allergic 235 00:14:18,740 --> 00:14:26,700 reaction is, um, is going to be commonly seen in maybe more complicated things 236 00:14:26,700 --> 00:14:35,340 that we see like serum sickness or, um, um, just other more serious things and stuff. 237 00:14:35,340 --> 00:14:38,180 So just for completeness, I wanted to mention those as well. 238 00:14:38,220 --> 00:14:38,740 That's good. 239 00:14:38,740 --> 00:14:39,140 Okay. 240 00:14:39,140 --> 00:14:43,380 So we have immediate allergic reactions, which deals with IgG. 241 00:14:43,620 --> 00:14:43,780 Yeah. 242 00:14:43,780 --> 00:14:44,220 IgE. 243 00:14:44,220 --> 00:14:44,780 IgE. 244 00:14:44,780 --> 00:14:45,340 Thank you. 245 00:14:45,620 --> 00:14:51,100 Then we have long-term or basically delayed allergic, which deals with your T cells. 246 00:14:51,140 --> 00:14:51,620 Yes. 247 00:14:51,620 --> 00:14:59,340 And then we have, um, we have the cytotoxic, which deals with, uh, it's 248 00:14:59,340 --> 00:15:03,740 an internal problem, which causes cells to essentially attack other cells or your 249 00:15:03,740 --> 00:15:04,220 tissues. 250 00:15:04,220 --> 00:15:08,540 So for example, they might attack lung tissue, for an example, cause they get 251 00:15:08,540 --> 00:15:11,780 confused and they might attack the lung tissue and cause damage there. 252 00:15:11,940 --> 00:15:12,340 Yeah. 253 00:15:12,540 --> 00:15:18,940 Or you have the, um, the, the immunocomplex, which is the, the idea. 254 00:15:18,940 --> 00:15:20,300 So it's not local. 255 00:15:20,300 --> 00:15:25,220 It basically spreads through serum AKA blood and in lymph and other fluids. 256 00:15:25,620 --> 00:15:26,020 Yes. 257 00:15:26,020 --> 00:15:30,580 And causes some sort of an inflammatory, you know, reaction things like histamines. 258 00:15:30,580 --> 00:15:33,980 And so they'll be get carried around the whole body because they're 259 00:15:33,980 --> 00:15:35,260 going to be in the bloodstream. 260 00:15:35,740 --> 00:15:36,100 Okay. 261 00:15:36,100 --> 00:15:41,060 But I'm thinking the ones that we, as you know, our cells would deal with most 262 00:15:41,100 --> 00:15:45,220 commonly, we're are going to be those immediate hypersensitivity reactions or 263 00:15:45,220 --> 00:15:47,820 those delayed hypersensitivity reactions. 264 00:15:47,820 --> 00:15:52,780 So, and again, the things, somebody might be thinking, well, what all causes 265 00:15:52,820 --> 00:15:54,100 allergic reactions? 266 00:15:54,420 --> 00:15:58,780 And there's a list and this won't be an uncommon, I mean, this'll be a familiar 267 00:15:58,780 --> 00:15:59,700 list to most people. 268 00:15:59,700 --> 00:16:07,540 So pollen, big, big one mold, animal dander, dust or dust mites, which people are 269 00:16:07,540 --> 00:16:12,300 certainly aware of latex, anybody that's had a latex allergy, that's definitely 270 00:16:12,300 --> 00:16:13,540 part of an allergic reaction. 271 00:16:13,540 --> 00:16:18,460 That's been a kind of a newer allergic reaction, I'd say though, it's probably 272 00:16:18,460 --> 00:16:21,980 now 25 or 30 years old, but it's definitely a newer one. 273 00:16:22,660 --> 00:16:30,900 Medications, insect stings and bites, foods, different foods such as shellfish, 274 00:16:31,340 --> 00:16:36,620 eggs, milk, tree nuts, peanuts and wheat. 275 00:16:36,820 --> 00:16:38,140 Those are the common ones. 276 00:16:38,140 --> 00:16:43,420 Chemical irritants can also cause an allergic reaction and things like poison 277 00:16:43,420 --> 00:16:45,580 ivy, poison oak and poison sumac. 278 00:16:45,940 --> 00:16:50,580 So those are, that's the, the pretty much the common list of allergic, allergens 279 00:16:50,580 --> 00:16:51,940 that cause allergic reaction. 280 00:16:51,940 --> 00:16:52,940 Those are the low hanging fruit. 281 00:16:52,940 --> 00:16:54,500 They might affect most people. 282 00:16:54,540 --> 00:16:55,060 Right. 283 00:16:55,340 --> 00:17:01,980 There's a stat out there, the 25% of people experience some type of allergic 284 00:17:01,980 --> 00:17:04,420 reaction and that's 25%. 285 00:17:04,420 --> 00:17:09,100 I believe that's either America or that's of the world, but if you use America 286 00:17:09,100 --> 00:17:13,780 as a sample population, then, you know, it's 25% of almost 8 billion people. 287 00:17:13,820 --> 00:17:16,180 So that's about 2 billion people, which is pretty amazing. 288 00:17:16,860 --> 00:17:17,380 There you go. 289 00:17:17,380 --> 00:17:22,700 So let's, let's, let's talk about an example, because I think a lot of people, 290 00:17:24,460 --> 00:17:26,700 maybe either have these allergies or they don't. 291 00:17:27,220 --> 00:17:29,940 I think a common one is hay fever. 292 00:17:29,940 --> 00:17:33,580 And so I think you're going to be talking about that, right? 293 00:17:33,580 --> 00:17:34,300 I let, yes. 294 00:17:34,340 --> 00:17:36,060 Let me, there's just a few other little details. 295 00:17:36,060 --> 00:17:37,220 I just wanted to throw in here. 296 00:17:37,460 --> 00:17:42,420 First of all is when we talk about those immediate hypersensitivity or allergic 297 00:17:42,420 --> 00:17:47,820 reactions, the things that can commonly cause those immediate type reactions are 298 00:17:47,820 --> 00:17:53,980 things like pollen, different foods, bee venom, and medications. 299 00:17:53,980 --> 00:17:55,420 So those are common for that allergic. 300 00:17:55,420 --> 00:17:56,980 They're common for people with allergies. 301 00:17:56,980 --> 00:18:00,060 And medications, so those are common for that allergic. 302 00:18:00,060 --> 00:18:02,620 And that's going to come, that's going to come into play in just a minute. 303 00:18:02,620 --> 00:18:03,820 As I talk about symptoms. 304 00:18:03,820 --> 00:18:07,820 And by immediate, we mean within minutes, minutes to hours, minutes to hours. 305 00:18:08,100 --> 00:18:13,860 Whereas those delayed hypersensitivity reactions may be more commonly caused by 306 00:18:13,900 --> 00:18:19,380 bacteria, fungi, chemicals, or plants. 307 00:18:19,700 --> 00:18:20,180 Okay. 308 00:18:20,860 --> 00:18:25,300 So you think, you think, well, how do I know if I'm having an allergic reaction? 309 00:18:25,300 --> 00:18:33,260 So the common symptoms that you see are going to be sneezing, a runny nose, maybe 310 00:18:33,260 --> 00:18:38,060 obstruction of your nasal passages, itchy, watery eyes. 311 00:18:38,980 --> 00:18:40,980 You can have eyelids swelling. 312 00:18:41,620 --> 00:18:45,300 You could have itching, just all body, all over, all over body itching. 313 00:18:45,460 --> 00:18:49,420 Interestingly too, you could have stomach pain or diarrhea to go along with an 314 00:18:49,420 --> 00:18:51,180 allergic reaction as well. 315 00:18:51,180 --> 00:18:57,180 And so those are typically manageable on your own, but the things, the ones that 316 00:18:57,180 --> 00:19:00,700 you want to be worried about are the ones that get more serious. 317 00:19:01,020 --> 00:19:07,740 So anytime that you have been exposed to some sort of an allergen and you have 318 00:19:07,740 --> 00:19:14,380 anything like difficulty breathing or your lips or your tongue starts swelling, 319 00:19:14,780 --> 00:19:20,140 or you have hives all over, or you start having pale, cool, or you have a 320 00:19:20,140 --> 00:19:26,460 pale, cool, damp skin, or you've got a fast or pounding heartbeat, you have 321 00:19:26,460 --> 00:19:32,500 significant nausea and vomiting, or you feel drowsy or confused or you faint, 322 00:19:32,540 --> 00:19:34,540 you're going to probably want to get some help. 323 00:19:34,820 --> 00:19:39,540 Sometimes it's a 911 call, especially if somebody's having difficulty breathing. 324 00:19:39,740 --> 00:19:44,260 So you need to be aware of that, you know, and sometimes people need to wear 325 00:19:44,620 --> 00:19:49,180 medical alert bracelets that tell, you know, anybody else that you've got an 326 00:19:49,180 --> 00:19:52,580 allergic reaction, a severe allergic reaction to something. 327 00:19:52,820 --> 00:19:53,340 Okay. 328 00:19:54,180 --> 00:19:59,100 Um, yeah, that's tough to say because if you don't know you're allergic to 329 00:19:59,100 --> 00:20:02,420 something, you're going to find out in that moment, which is crummy. 330 00:20:02,460 --> 00:20:02,780 Yeah. 331 00:20:02,820 --> 00:20:08,700 But there are some ways to diagnose allergies, you know, especially when 332 00:20:08,700 --> 00:20:14,060 they're not that severe, but you can, um, certainly by symptoms, you can tell 333 00:20:14,060 --> 00:20:15,580 whether or not you're allergic to something. 334 00:20:15,580 --> 00:20:20,660 If, if you had never been fine and all of a sudden you do something and you 335 00:20:20,660 --> 00:20:25,060 have some of these symptoms, you can feel pretty certain that maybe that was 336 00:20:25,060 --> 00:20:25,860 the cause of it. 337 00:20:26,140 --> 00:20:32,180 You can also, um, see an allergist and do things like the skin prick test where 338 00:20:32,180 --> 00:20:37,780 they will, they will, um, give you small little, you know, substances. 339 00:20:37,820 --> 00:20:42,020 Usually I think they do it on your back and see whether or not your body reacts 340 00:20:42,020 --> 00:20:46,100 to them to help you figure out whether you are allergic to cats, you know, or 341 00:20:46,100 --> 00:20:52,260 you are allergic to, uh, uh, pollen from cedar, you know, and that, that kind of 342 00:20:52,260 --> 00:20:52,620 thing. 343 00:20:52,940 --> 00:20:57,060 Um, you can also do, if it's foods that you're having issues with, you can either 344 00:20:57,060 --> 00:21:01,300 do a food elimination diet, or you can do a food challenge test as well too. 345 00:21:01,820 --> 00:21:02,020 Yeah. 346 00:21:02,020 --> 00:21:03,540 What's a food elimination diet? 347 00:21:03,980 --> 00:21:09,020 I think it's going to be when, um, you, if you've noticed something that you feel 348 00:21:09,020 --> 00:21:12,580 like might be causing something, you take it out of your diet and see whether or 349 00:21:12,580 --> 00:21:14,140 not your symptoms get better. 350 00:21:14,460 --> 00:21:17,900 Um, that can be kind of touch and go and kind of hit or miss and stuff. 351 00:21:17,900 --> 00:21:23,540 So, um, I think that you can also involve those in some of those, um, skin prick 352 00:21:23,540 --> 00:21:26,940 test type things as well too, like peanuts, you know, or something like that, 353 00:21:26,980 --> 00:21:30,260 you know, cause you, I would, if you have a severe reaction to peanuts, you 354 00:21:30,260 --> 00:21:34,900 wouldn't want to necessarily do a food challenge test with it, you know, and 355 00:21:34,900 --> 00:21:35,180 stuff. 356 00:21:35,180 --> 00:21:35,420 So, 357 00:21:35,420 --> 00:21:36,140 but I know what you mean. 358 00:21:36,140 --> 00:21:40,060 Like if you think that you might have a, uh, a wheat sensitivity as opposed to 359 00:21:40,060 --> 00:21:45,860 celiac disease, it's easier to cut wheat out of your diet, see how you feel from 360 00:21:45,860 --> 00:21:50,620 maybe a couple of weeks, um, or, you know, sugar or milk, milk as another one as 361 00:21:50,620 --> 00:21:51,620 well, dairy type things. 362 00:21:51,620 --> 00:21:52,980 And so, yes, absolutely. 363 00:21:53,300 --> 00:21:57,020 And a lot, a lot of times, you know, it's, it's, you know, there's so many things 364 00:21:57,020 --> 00:21:58,980 that could potentially be inside of you. 365 00:21:59,060 --> 00:22:04,460 That's a, that, that could be causing you malady, uh, which is why keeping, 366 00:22:04,460 --> 00:22:07,660 you know, don't rely too much on your intuition. 367 00:22:07,660 --> 00:22:12,500 Like your intuition should inform you how you feel, like I feel bad or I feel good. 368 00:22:12,500 --> 00:22:17,580 Obviously you feel things, but then, you know, go through the, keep proper 369 00:22:17,580 --> 00:22:22,700 documentation, find a good template of a food elimination diet so that you can be 370 00:22:22,700 --> 00:22:28,500 pretty rigorous about it because it's easy to draw conclusions, um, without 371 00:22:28,500 --> 00:22:29,500 being rigorous. 372 00:22:29,500 --> 00:22:35,220 So for example, um, you could eliminate, let's say you're feeling bad after eating 373 00:22:35,220 --> 00:22:38,820 a piece of bread, but you failed to include that you also drank a glass of 374 00:22:38,820 --> 00:22:40,780 wine with that piece of bread. 375 00:22:41,260 --> 00:22:46,420 So if you continue to eat, just cut out bread, if you don't often drink wine, 376 00:22:46,580 --> 00:22:50,500 then you might come to the conclusion that it was the bread that was causing 377 00:22:50,500 --> 00:22:51,620 you to feel that way. 378 00:22:52,180 --> 00:22:55,340 But then upon drinking wine again, maybe you only drink it with bread. 379 00:22:56,140 --> 00:22:58,540 You'll then conclude, Oh, it must be the bread. 380 00:22:58,540 --> 00:22:59,940 But really it was the red wine. 381 00:23:00,260 --> 00:23:05,020 So really keep in mind that you have, you might have certain biases 382 00:23:05,060 --> 00:23:06,140 towards certain foods. 383 00:23:06,300 --> 00:23:11,220 Um, I know, uh, bread out there is, is a common culprit for, for being, uh, fairly 384 00:23:11,220 --> 00:23:15,300 demonized and who wants to demonize red wine, uh, cause it's quite delicious. 385 00:23:15,700 --> 00:23:20,300 But if you're really wanting to figure out what's going on with you, you also 386 00:23:20,300 --> 00:23:24,620 have to be aware of your biases and also biases that have been thrown at you. 387 00:23:24,620 --> 00:23:29,340 Um, but my popular media, and I'm not saying that you might not have a gluten 388 00:23:29,340 --> 00:23:33,140 sensitivity or, um, but if you really want to know what's going on with your 389 00:23:33,140 --> 00:23:39,580 body, um, you have to highlight even the foods that aren't highlighted by a lot 390 00:23:39,580 --> 00:23:43,260 of publications, um, you know, there's, there's a lot of things out there that 391 00:23:43,260 --> 00:23:45,140 could potentially be a potential allergen. 392 00:23:45,660 --> 00:23:51,260 Um, we also talked about the food challenge, which I assume, I assume is 393 00:23:51,260 --> 00:23:56,980 similar, um, a type of way of figuring out, you know, what foods are, are good 394 00:23:56,980 --> 00:24:01,060 for you and which aren't the problem is with a lot of these is that they're, 395 00:24:01,180 --> 00:24:06,380 they're difficult to do because food is so delicious and we eat so much of 396 00:24:06,500 --> 00:24:08,620 different types of food at a meal. 397 00:24:09,060 --> 00:24:12,820 So in order to really do this fairly scientifically, you would basically 398 00:24:12,820 --> 00:24:14,580 need to eat one food. 399 00:24:14,740 --> 00:24:18,380 You, one way I've heard about doing this is that you eliminate all foods from your 400 00:24:18,380 --> 00:24:22,900 diet, you almost go on a fast for a couple of days and then you reintroduce 401 00:24:22,900 --> 00:24:27,860 foods one at a time, um, into your diet, either days or week at a time. 402 00:24:28,660 --> 00:24:33,340 And then once you get to the one that causes you discomfort, then you kind of 403 00:24:33,340 --> 00:24:37,140 have a semblance of an idea is like, Oh, okay, it's this one that, that 404 00:24:37,140 --> 00:24:39,100 caused me the problem, but that's really hard to do. 405 00:24:39,140 --> 00:24:43,180 It's really hard to just eat kale and then do kale and broccoli and new kale 406 00:24:43,180 --> 00:24:44,700 and Brussels sprouts, et cetera. 407 00:24:44,700 --> 00:24:49,060 But on the whole, um, one thing to really keep in mind is like, if you are going 408 00:24:49,060 --> 00:24:54,060 to eat food, um, other than things that can cause like anaphylactic shock, like 409 00:24:54,060 --> 00:24:59,020 peanuts and things like that, um, tend to eat foods that aren't processed, um, 410 00:24:59,020 --> 00:25:04,180 try to eat a lot more colors, you know, Brussels sprouts and sweet potatoes on 411 00:25:04,180 --> 00:25:04,820 your plate. 412 00:25:05,220 --> 00:25:08,180 And if you are going to get meat, you know, make sure it's sustainably 413 00:25:08,180 --> 00:25:13,540 sourced, um, because a lot of those, a lot of these, um, you know, you're 414 00:25:13,540 --> 00:25:18,220 going to get a lot of those, a lot of these additives, um, even, even though 415 00:25:18,220 --> 00:25:22,540 they might be safe for the whole of the population, they could be causing a harm 416 00:25:22,540 --> 00:25:25,740 for you and they might be that trigger. 417 00:25:25,900 --> 00:25:30,060 So diminishing the number of ingredients might also diminish the probability of 418 00:25:30,060 --> 00:25:31,500 having some of these allergic reactions. 419 00:25:31,980 --> 00:25:35,220 Let me add just a couple of other little points about food challenge tests. 420 00:25:35,220 --> 00:25:38,820 It does seem to, as I've done a little bit of additional research that they're 421 00:25:38,820 --> 00:25:42,980 actually done in a controlled environment, like, like maybe an allergist's office. 422 00:25:42,980 --> 00:25:47,820 Because I think if you did have a severe reaction, then there is medical personnel 423 00:25:47,860 --> 00:25:53,020 readily available to help you, but you will determine to see whether or not 424 00:25:53,020 --> 00:25:57,460 you've got something going on with that particular food, um, under a 425 00:25:57,460 --> 00:25:58,700 controlled environment. 426 00:25:58,820 --> 00:26:02,980 Um, it may be that you eat small amounts and then you have gradually increasing 427 00:26:02,980 --> 00:26:05,540 amounts to see what kind of a reaction you have. 428 00:26:06,060 --> 00:26:06,500 Um, 429 00:26:06,540 --> 00:26:10,700 yeah, I know that's been done with infants who have a note because be having 430 00:26:10,700 --> 00:26:13,380 peanut allergy is, is fairly genetic. 431 00:26:13,460 --> 00:26:19,100 And sometimes you get tested for it as an infant and by dosing small amounts of 432 00:26:19,100 --> 00:26:22,580 the peanut protein that causes the allergic reaction, you can actually 433 00:26:22,580 --> 00:26:24,020 diminish the response. 434 00:26:24,540 --> 00:26:29,540 Um, it's almost kind of like an inoculation, you know, to this type of antigen 435 00:26:29,620 --> 00:26:30,660 or this allergen. 436 00:26:31,140 --> 00:26:34,500 And so if you have kids out there and you're worried about them getting 437 00:26:34,540 --> 00:26:38,020 allergies later in life, I would strongly do some research into the hygiene 438 00:26:38,020 --> 00:26:41,540 hypothesis and let your kids play outside and get dirty. 439 00:26:41,540 --> 00:26:46,340 And, um, because it really does wonder for their immune system and training 440 00:26:46,340 --> 00:26:49,860 it and how to moderate itself because if it doesn't moderate itself, it can 441 00:26:49,860 --> 00:26:50,900 kind of go crazy. 442 00:26:51,380 --> 00:26:55,100 Um, so if you want to kind of delay some of these allergic responses down the 443 00:26:55,100 --> 00:26:59,460 road, I would highly recommend you let your kids roll in the mud a bit within 444 00:26:59,460 --> 00:26:59,860 reason. 445 00:27:00,340 --> 00:27:04,420 Um, I think too, also just an additional fact about the food challenge. 446 00:27:04,420 --> 00:27:08,900 It seems that food challenge tests are done when you've looked at other types 447 00:27:08,900 --> 00:27:13,580 of tests, maybe like skin allergy tests and, um, maybe a medical history and 448 00:27:13,580 --> 00:27:15,300 things seem to be inconclusive. 449 00:27:15,300 --> 00:27:18,700 So it's going to be kind of a down the line type of a test as well too. 450 00:27:18,820 --> 00:27:19,220 Okay. 451 00:27:19,420 --> 00:27:19,980 That's great. 452 00:27:20,380 --> 00:27:20,700 Okay. 453 00:27:20,700 --> 00:27:24,140 So we've talked about some of the ways that you can prevent allergies. 454 00:27:24,140 --> 00:27:26,420 We've talked about how allergies can form. 455 00:27:26,860 --> 00:27:29,420 Now let's imagine I'm having an allergic reaction. 456 00:27:29,620 --> 00:27:30,860 I'm going through it. 457 00:27:31,260 --> 00:27:32,980 I've got, you know, puffy eyes. 458 00:27:32,980 --> 00:27:34,860 I've got shortness of breath, et cetera. 459 00:27:34,860 --> 00:27:38,780 What can I do to alleviate, uh, my pain? 460 00:27:39,580 --> 00:27:44,740 Um, so, so there's a couple of things that are, are there's a couple, a couple 461 00:27:44,740 --> 00:27:52,140 of, um, I guess, or there's a, I guess, treatment options for people with allergies. 462 00:27:52,180 --> 00:27:57,740 First thing, uh, it kind of seems like a, you know, of course is that if you are 463 00:27:57,740 --> 00:28:02,740 aware of something that causes you to have an allergic reaction, you might try 464 00:28:02,740 --> 00:28:07,740 avoiding that thing, like if cats are the thing that caused you to be absolutely 465 00:28:07,740 --> 00:28:11,460 miserable, that you can't breathe, your eyes are itching and your nose is runny 466 00:28:11,460 --> 00:28:15,660 all the time, you may not be able to own a cat, you know, that kind of thing. 467 00:28:16,020 --> 00:28:19,940 Um, so you're going to try to avoid something that might get a hairless cat. 468 00:28:20,020 --> 00:28:20,660 Yes. 469 00:28:21,100 --> 00:28:25,460 You could get a hairless cat or let's, let's talk about dust or dust mites in 470 00:28:25,460 --> 00:28:28,980 your house, you know, which is in everyone's home, no matter how clean you are. 471 00:28:28,980 --> 00:28:33,060 I mean, so there might be some certain types of filters that you could put in 472 00:28:33,060 --> 00:28:38,860 your ventilation system, um, in order to filter out the dust and dust mites and 473 00:28:38,860 --> 00:28:44,660 stuff so that you might see an improvement in your, um, in your, um, uh, 474 00:28:44,860 --> 00:28:48,860 allergic symptoms, if that happens to be the thing that's causing you problems. 475 00:28:49,620 --> 00:28:56,180 Um, if you, uh, you know, for, for dust and stuff as well, too, keeping your house 476 00:28:56,180 --> 00:28:59,780 clean, you know, making sure that you don't have carpets in your house, 477 00:29:00,700 --> 00:29:05,380 you keeping your, no carpet in the home because dust, dust, dust mites like to 478 00:29:05,380 --> 00:29:06,340 live in the carpet. 479 00:29:06,380 --> 00:29:11,700 So, you know, hardwood floors or tile, you know, something that, a linoleum, 480 00:29:11,740 --> 00:29:15,460 you know, something that's not carpet would be good for that circumstance. 481 00:29:15,980 --> 00:29:21,460 Um, sometimes you also want to, um, encase your mattress and box springs and 482 00:29:21,460 --> 00:29:25,300 pillows in what they call mite impermeable materials. 483 00:29:25,300 --> 00:29:27,460 And also then wash your bedding every week. 484 00:29:27,700 --> 00:29:31,500 Um, again, this is talking about somebody who might be more sensitive to dust 485 00:29:31,500 --> 00:29:32,700 mites and others and stuff. 486 00:29:33,380 --> 00:29:35,580 Um, you know, you can also be allergic to cockroaches. 487 00:29:35,980 --> 00:29:40,180 Um, so you want to keep your house clean and you want to keep your food tightly 488 00:29:40,180 --> 00:29:44,580 sealed and stored properly and then treat infested areas for, if you have 489 00:29:44,580 --> 00:29:45,780 problems with cockroaches. 490 00:29:46,020 --> 00:29:50,980 I know one time I lived in a, in a city that rained a whole lot more than where 491 00:29:50,980 --> 00:29:51,780 I live now. 492 00:29:51,780 --> 00:29:56,100 And so cockroaches were definitely a problem, regardless of how clean I kept 493 00:29:56,100 --> 00:29:56,740 my home. 494 00:29:56,740 --> 00:30:00,780 So again, it's just, it's not always implying that you are not a good 495 00:30:00,780 --> 00:30:01,580 housekeeper and stuff. 496 00:30:01,580 --> 00:30:04,780 It's just, sometimes it's environmental problems and stuff. 497 00:30:05,060 --> 00:30:05,300 Yeah. 498 00:30:05,300 --> 00:30:08,460 Is it something that the cockroach is excrete that you're allergic to? 499 00:30:08,500 --> 00:30:09,100 I believe it is. 500 00:30:09,100 --> 00:30:09,380 Okay. 501 00:30:09,420 --> 00:30:10,380 That's really interesting. 502 00:30:10,540 --> 00:30:11,020 Yes. 503 00:30:11,580 --> 00:30:18,900 Um, so I mean, those, those, um, what you've seen in this store, I've talked 504 00:30:18,900 --> 00:30:22,700 to, I talked about putting filters into your, you know, ventilation system. 505 00:30:22,980 --> 00:30:24,500 They're called HEPA filters. 506 00:30:24,700 --> 00:30:30,460 HEPA stands for high efficiency particulate air or HEPA filter. 507 00:30:30,820 --> 00:30:36,460 Um, and so they're going to help try to remove pollen and mold spores and cat 508 00:30:36,460 --> 00:30:41,500 allergens from your household air, but they can't remove the fecal materials 509 00:30:41,500 --> 00:30:42,940 from house dust mites. 510 00:30:43,100 --> 00:30:45,420 That's what you're allergic from, from dust mites. 511 00:30:45,420 --> 00:30:49,380 And it, it's just too small to be filtered and that's why they don't work for, 512 00:30:49,460 --> 00:30:49,980 for dust mites. 513 00:30:49,980 --> 00:30:52,020 And that's why you recommend washing your bedding. 514 00:30:52,020 --> 00:30:52,340 Right. 515 00:30:52,340 --> 00:30:54,380 Or sometimes you may have to encase it and stuff. 516 00:30:54,380 --> 00:30:54,700 Yes. 517 00:30:54,740 --> 00:30:55,900 And mites are very small. 518 00:30:55,900 --> 00:30:57,580 I don't think you'll be able to see them with the naked eye. 519 00:30:57,580 --> 00:30:57,900 Right. 520 00:30:57,900 --> 00:30:58,300 Correct. 521 00:30:58,500 --> 00:30:59,060 Right. 522 00:30:59,380 --> 00:31:04,340 Uh, sometimes those filters are pretty expensive and so that can be costly and 523 00:31:04,340 --> 00:31:06,940 stuff and so, and they may not be effective for all patients. 524 00:31:07,180 --> 00:31:12,140 Also too, you can, your vacuum cleaner can also have a HEPA filter on it as well too. 525 00:31:12,140 --> 00:31:15,580 So it just depends on what you need that you can try some of those things. 526 00:31:16,140 --> 00:31:22,260 Um, if you need some medication therapy, then the categories that you're going to 527 00:31:22,260 --> 00:31:29,340 see used most commonly are going to be antihistamines, decongestants. 528 00:31:29,980 --> 00:31:33,420 You might see some intranasal corticosteroids used. 529 00:31:33,860 --> 00:31:39,420 Um, there is a drug called Iprotropium that is an anticholinergic, so it can dry, 530 00:31:39,420 --> 00:31:42,940 it can cause your, your nasal passages to constrict. 531 00:31:42,940 --> 00:31:46,740 So you don't have as much of a runny nose if you really suffer with that. 532 00:31:47,260 --> 00:31:53,700 Um, sometimes, uh, if you, uh, like for little kiddos that are too young to 533 00:31:53,700 --> 00:31:58,140 receive some of these prescription therapies, if you use, um, salt water, 534 00:31:58,140 --> 00:32:03,140 normal saline, saline, uh, intranasal solutions or washes that can sometimes 535 00:32:03,140 --> 00:32:04,140 help wash things out. 536 00:32:04,140 --> 00:32:04,740 Like a neti pot. 537 00:32:04,780 --> 00:32:05,300 Right. 538 00:32:05,300 --> 00:32:09,580 Um, and sometimes people might even need oral corticosteroids as well too. 539 00:32:09,580 --> 00:32:10,620 That's not as common. 540 00:32:11,420 --> 00:32:17,900 So the other thing too, that you'll see, um, in, um, for certain circumstances 541 00:32:17,940 --> 00:32:21,820 is going to be, um, what we call allergen immunotherapy. 542 00:32:22,220 --> 00:32:26,420 So you can either take, there are some oral therapies or you've got, it's 543 00:32:26,420 --> 00:32:29,460 when you see, hear about people getting allergy shots. 544 00:32:29,820 --> 00:32:34,660 So they're going to give you some of that thing that's subject to 545 00:32:34,660 --> 00:32:38,380 that substance that you're allergic to and small amounts so that you can, 546 00:32:38,380 --> 00:32:43,740 your body can build up a reaction to it so that when you get exposed to the real 547 00:32:43,740 --> 00:32:47,060 thing, you'll have a much less of a response to it as well. 548 00:32:47,340 --> 00:32:52,500 You'll see that a lot when you get the, when you, um, if it's, uh, you know, uh, 549 00:32:52,540 --> 00:32:56,340 uh, pollen, you know, grass, that type of thing and stuff. 550 00:32:56,340 --> 00:32:58,580 So, yeah, that's, that's really well said. 551 00:32:58,580 --> 00:33:04,460 I actually think that advice not only goes towards getting tested for allergies. 552 00:33:04,460 --> 00:33:06,260 It's just good life advice in general. 553 00:33:06,260 --> 00:33:11,060 I think this is straying off topic a little bit, but the idea that things 554 00:33:11,060 --> 00:33:15,220 should always be perfect all the time and that you should never suffer 555 00:33:15,220 --> 00:33:17,420 from anything, um, is a misnomer. 556 00:33:17,420 --> 00:33:24,260 I think sometimes learning how to suffer is, uh, is a great way to live through 557 00:33:24,260 --> 00:33:27,860 life feeling also laughing through suffering is, is quite good. 558 00:33:27,860 --> 00:33:32,900 I remember there was a, um, there was a politician who used to, uh, he was 559 00:33:32,900 --> 00:33:38,220 a Navy seal and, um, Afghanistan and he, unfortunately got hit with an IUD and 560 00:33:38,220 --> 00:33:39,300 then knocked his eye out. 561 00:33:39,820 --> 00:33:45,140 Um, and, uh, and when his friend, you know, his rest of his crew came in and he 562 00:33:45,140 --> 00:33:48,260 basically said, oh, it's a good thing they left me the other one, you know, as 563 00:33:48,940 --> 00:33:56,260 this immediately after getting hit with a, an IUD, um, so this idea that there's 564 00:33:56,260 --> 00:33:59,340 going to be this time where things are going to function perfectly and you're 565 00:33:59,340 --> 00:34:02,540 going to get your house clean enough and your body is going to feel like it did 566 00:34:02,540 --> 00:34:07,380 when you were, you know, 10, if you're listening and you're older than 10 is 567 00:34:07,380 --> 00:34:11,940 not good, but it's definitely working towards getting to a place where you feel 568 00:34:11,940 --> 00:34:15,740 like that you're making incremental incremental process, uh, progress. 569 00:34:15,780 --> 00:34:22,100 There's no, there's no, um, Oh, what's the word I'm thinking of the cure all. 570 00:34:22,300 --> 00:34:23,100 What's the word? 571 00:34:23,700 --> 00:34:24,060 Yeah. 572 00:34:24,060 --> 00:34:26,660 There's no panacea out there that does not exist. 573 00:34:26,660 --> 00:34:27,500 It's all trade-offs. 574 00:34:27,500 --> 00:34:32,740 So if you have an allergic reaction to something, essentially you are then 575 00:34:32,740 --> 00:34:37,060 working to just reduce symptoms and, um, some things are better than others. 576 00:34:37,300 --> 00:34:40,860 Um, there's actually, I remember listening to this other podcast I listened 577 00:34:40,860 --> 00:34:48,580 to called radio lab about this man who, uh, went to, uh, Cameroon and he walked 578 00:34:48,580 --> 00:34:49,780 around in the latrines. 579 00:34:49,860 --> 00:34:54,340 If you don't know what a latrine is, uh, don't look up images, but it's essentially 580 00:34:54,340 --> 00:34:56,460 where people go to the restroom collectively. 581 00:34:56,460 --> 00:34:57,820 And it's no, there's no plumbing. 582 00:34:57,860 --> 00:35:00,100 It's just a pit that everyone goes to. 583 00:35:00,100 --> 00:35:02,660 And he walked through that pit barefoot. 584 00:35:03,260 --> 00:35:10,060 Um, the purpose was to get infected with this, um, certain parasite called a hook 585 00:35:10,060 --> 00:35:15,740 worm and a hook worm usually goes into your body and actually attached to your 586 00:35:15,740 --> 00:35:21,900 small intestine, um, it actually can cause some pretty, um, I don't know about 587 00:35:21,900 --> 00:35:26,980 painful, but it can cause some severe, um, digestional problems, but in the proper 588 00:35:26,980 --> 00:35:33,580 dose, what it did for him at least is that he had severe hay fever and he's from 589 00:35:33,580 --> 00:35:35,740 England and the hay fever was quite bad. 590 00:35:35,740 --> 00:35:38,060 And, um, we also call that allergic rhinitis. 591 00:35:38,620 --> 00:35:43,940 And when he went back to England after infecting himself, his allergic rhinitis 592 00:35:43,940 --> 00:35:48,220 had gone away because, but based on what I said earlier about the hygiene 593 00:35:48,220 --> 00:35:52,220 hypothesis, his immune system had bigger problems to worry about, which was the 594 00:35:52,220 --> 00:35:56,500 hook worms and the allergens that they were secreting in his small intestine. 595 00:35:57,340 --> 00:36:03,100 And it didn't have time to worry about, um, the allergens coming 596 00:36:03,100 --> 00:36:04,940 from the pollen from the plants. 597 00:36:05,140 --> 00:36:06,300 So there's some wisdom there. 598 00:36:06,300 --> 00:36:07,340 This is this idea. 599 00:36:07,340 --> 00:36:11,380 Can we coexist with parasites or can we maybe extract the chemical from the 600 00:36:11,380 --> 00:36:14,540 parasite and find a way to dampen our immune system? 601 00:36:14,580 --> 00:36:17,180 I think it'll be, it's going to be really interesting to figure out because I 602 00:36:17,180 --> 00:36:20,780 think a lot of people suffer from allergies, especially in richer countries. 603 00:36:20,780 --> 00:36:23,900 And it would be really nice way to diminish some of their suffering. 604 00:36:24,380 --> 00:36:29,180 So I just wanted to bring that in the idea that we're all just kind of figuring 605 00:36:29,180 --> 00:36:30,940 out the best solution here. 606 00:36:31,420 --> 00:36:35,220 Um, and don't think that things are just going to automatically just be a hundred 607 00:36:35,220 --> 00:36:35,820 percent better. 608 00:36:35,860 --> 00:36:38,620 We're all just progressing towards some standard that we can live with. 609 00:36:39,220 --> 00:36:40,940 I think you can still have our rich life. 610 00:36:40,940 --> 00:36:44,300 If you'd suffer, suffer from an allergy though, because we've got a lot of 611 00:36:44,300 --> 00:36:48,540 options to help people to feel better. 612 00:36:48,860 --> 00:36:53,180 Um, just one extra caveat about immune therapy or immunotherapy. 613 00:36:53,420 --> 00:36:58,420 Um, it can take several months to, and if you're taking either these immune 614 00:36:58,460 --> 00:37:03,460 therapy tablets, pills, or you're getting an allergy shots, sometimes can take a 615 00:37:03,460 --> 00:37:05,540 couple of months before you start seeing results. 616 00:37:05,540 --> 00:37:08,780 So don't think immediate, you know, for that either and stuff. 617 00:37:08,780 --> 00:37:11,180 So, yeah, we live in a world of instant gratification. 618 00:37:11,180 --> 00:37:14,180 Uh, biology works much slower, so give it some time. 619 00:37:14,620 --> 00:37:18,140 Um, and so just a couple of takeaways that I just wanted to just leave you 620 00:37:18,140 --> 00:37:24,860 with as far as treatments for allergies, um, and, and the symptoms that happen, 621 00:37:25,100 --> 00:37:29,940 you know, from them, uh, a lot of, I know a lot of these, as far as things like 622 00:37:29,940 --> 00:37:34,060 decongestants, nanohistamines, we're talking about things like, you know, itchy 623 00:37:34,060 --> 00:37:39,020 watery eyes and runny nose, those types of things rather than more serious allergic 624 00:37:39,020 --> 00:37:44,860 reactions, but, you know, uh, so a decongestant is going to be the type of 625 00:37:45,100 --> 00:37:51,340 medication that is most prompt is going to be most commonly used to manage those 626 00:37:51,340 --> 00:37:52,500 types of symptoms. 627 00:37:52,940 --> 00:38:02,140 Um, and, um, you, you know, again, are going to, um, um, if you're going to use 628 00:38:02,140 --> 00:38:07,180 a decongestant though, if you have some underlying diseases, like, um, if you 629 00:38:07,180 --> 00:38:14,300 have high blood pressure, um, or, um, glaucoma, um, even diabetes, sometimes 630 00:38:14,300 --> 00:38:18,700 the medications that are used to treat that can be harmful to those diseases. 631 00:38:18,700 --> 00:38:22,220 So it's definitely something to talk with your healthcare provider about first. 632 00:38:22,460 --> 00:38:26,060 I would not, um, just go ahead and take it because you could end up with some 633 00:38:26,060 --> 00:38:30,460 other issues if you don't, um, talk with them about, you know, how to take those 634 00:38:30,460 --> 00:38:31,820 and stuff with those conditions. 635 00:38:31,820 --> 00:38:39,740 Um, if you, um, have some other diseases that show up along with your allergy 636 00:38:39,740 --> 00:38:45,740 symptoms, let's say your ears start hurting or, um, you start feeling running 637 00:38:45,740 --> 00:38:52,460 a fever, um, you know, then, um, or your, um, you feel, you know, your use to have 638 00:38:52,460 --> 00:38:57,260 an awful cough chest pain in your, in your, as you cough and stuff that could, 639 00:38:57,260 --> 00:39:01,900 that those are all some, all indicators that maybe something more serious is 640 00:39:01,900 --> 00:39:02,620 going on. 641 00:39:02,780 --> 00:39:05,740 And again, you'd need to see a healthcare provider for those well too. 642 00:39:06,460 --> 00:39:07,500 That's good advice. 643 00:39:07,580 --> 00:39:07,900 Yeah. 644 00:39:07,900 --> 00:39:12,860 I remember y'all with side effects, you're, you're putting a chem, especially 645 00:39:12,860 --> 00:39:17,180 when you take medication or anything for that matter, even food, that it's going 646 00:39:17,180 --> 00:39:21,980 all over your body and wherever there is a receptor that will take that thing 647 00:39:21,980 --> 00:39:25,820 that you put into your body, it will fit in there like a lock and key. 648 00:39:25,820 --> 00:39:30,220 And it will basically start the mechanism that it was designed to do. 649 00:39:31,020 --> 00:39:37,980 And so when these drugs are designed, you, you're, you're trying to target an 650 00:39:37,980 --> 00:39:41,980 area to alleviate suffering, AKA let's use the decongestant. 651 00:39:41,980 --> 00:39:49,260 You want to reduce congestion, but upon doing the clinical trials, they also 652 00:39:49,260 --> 00:39:51,340 found out that there were other side effects. 653 00:39:51,340 --> 00:39:54,620 So they have to disclose these side effects and it wasn't purposeful that 654 00:39:54,620 --> 00:39:57,500 these drug companies, you know, pick these side effects. 655 00:39:57,500 --> 00:39:59,340 They just happen to happen inside of the body. 656 00:39:59,340 --> 00:40:03,900 And so you tell them to the patients and say, just as a risk, be like, Hey, we 657 00:40:03,900 --> 00:40:06,140 know you're suffering from deep, from congestion. 658 00:40:06,860 --> 00:40:09,820 Just want to let you know, if you have high blood pressure, it might not be 659 00:40:09,820 --> 00:40:14,060 worth the risk to take it because the side effects from this might be worse 660 00:40:14,060 --> 00:40:14,940 than the congestion. 661 00:40:15,740 --> 00:40:19,660 So that's why it's really good to know where you are at personally. 662 00:40:19,900 --> 00:40:23,660 So that when you take drugs, you kind of can do your own risk reward. 663 00:40:23,660 --> 00:40:26,700 Calculation, because sometimes it might not be worth it. 664 00:40:26,700 --> 00:40:31,020 So even though being congested, isn't fun, it's also not fun to deal with, you 665 00:40:31,020 --> 00:40:33,260 know, blood pressure problems that might come as a side effect. 666 00:40:33,740 --> 00:40:38,860 Or you might be a patient that would then benefit from an intranasal corticosteroid 667 00:40:38,860 --> 00:40:42,940 rather than taking a decongestant because there's other options that can be used 668 00:40:42,940 --> 00:40:44,700 as well to manage that symptom. 669 00:40:45,420 --> 00:40:46,140 That's well said. 670 00:40:46,140 --> 00:40:51,500 One other thing that I just, I neglected to say to you, if you, if you are 671 00:40:51,500 --> 00:40:58,300 identified as having a pretty significant allergic reaction to, let's say peanuts 672 00:40:59,180 --> 00:41:06,380 or some other type of an allergen, sometimes you will be prescribed what 673 00:41:06,380 --> 00:41:08,540 they call an emergency kit. 674 00:41:08,540 --> 00:41:13,340 And usually it has epinephrine in it, which is something that will help to 675 00:41:13,340 --> 00:41:19,420 counter the allergen response as far as causing the significant vasodilation 676 00:41:19,420 --> 00:41:23,580 because epinephrine is going to cause things to constrict up and stuff. 677 00:41:23,900 --> 00:41:28,940 And so, um, make sure that you have that available and make sure that you 678 00:41:28,940 --> 00:41:30,380 check the expiration date on it. 679 00:41:30,700 --> 00:41:31,020 Yeah. 680 00:41:31,020 --> 00:41:35,180 And we should mention epinephrine is a hormone that naturally occurs in your 681 00:41:35,180 --> 00:41:35,660 body. 682 00:41:36,460 --> 00:41:41,020 So it is very readily used and biodegraded in your body. 683 00:41:41,660 --> 00:41:45,180 So it's essentially there, just like my mom said, to counter the effects. 684 00:41:45,180 --> 00:41:49,500 So this is a, this is not a foreign, uh, pharmaceutical that was created. 685 00:41:49,500 --> 00:41:52,940 It was something that was extracted from the human body and then concentrated. 686 00:41:53,420 --> 00:41:55,740 And let me also add an extra point to that as well, too. 687 00:41:55,740 --> 00:41:59,180 If, if you have a situation where you do need to use the epinephrine, then you 688 00:41:59,180 --> 00:42:03,100 need to contact your healthcare professional either, I mean, healthcare 689 00:42:03,100 --> 00:42:07,420 professional as well to let them know, you know, that you had to give it or 690 00:42:07,420 --> 00:42:11,260 that you gave it to your child or you're on your way to the emergency room or 691 00:42:11,260 --> 00:42:13,740 you need to call 911, you know, as well, too. 692 00:42:13,740 --> 00:42:17,340 If you're, if you're seeing really like somebody's having really difficulty 693 00:42:17,340 --> 00:42:21,660 breathing, um, have a really crazy heart rate or whatever and need some help as 694 00:42:21,660 --> 00:42:22,140 well too. 695 00:42:22,620 --> 00:42:26,300 So when you walk out, you know, you'll have your keys, wallet, phone, and your 696 00:42:26,300 --> 00:42:28,940 EpiPen, which is one thing to add to your repertoire. 697 00:42:29,180 --> 00:42:29,500 Right. 698 00:42:29,500 --> 00:42:30,140 Absolutely. 699 00:42:30,700 --> 00:42:32,380 So, well, fantastic. 700 00:42:32,380 --> 00:42:34,220 I was, I was just do a little overview. 701 00:42:34,220 --> 00:42:39,580 So we've got, um, allergies, which are caused by allergens getting into your 702 00:42:39,580 --> 00:42:40,060 body. 703 00:42:40,540 --> 00:42:42,380 And normally they would do nothing. 704 00:42:42,380 --> 00:42:46,060 But every now and then they're going to cause a little haywire, whether that's, 705 00:42:46,460 --> 00:42:52,300 you know, essentially causing your immune system to kick into gear and, um, cause 706 00:42:52,300 --> 00:42:55,260 some of the effects that the immune system would normally do when fighting an 707 00:42:55,260 --> 00:43:00,060 infection from a bacteria and virus, which is causing vasodilation, which 708 00:43:00,060 --> 00:43:04,460 causes swelling or even releasing histamines, which do the similar thing, 709 00:43:04,540 --> 00:43:09,180 bruh, bronchoconstriction, which causes your tightening of your chest and also 710 00:43:09,420 --> 00:43:11,180 increasing mucus production. 711 00:43:11,180 --> 00:43:13,100 Which can cause you to feel quite stuffy. 712 00:43:13,500 --> 00:43:18,540 Um, and also sometimes even swelling in your eyes or even in your ears or, and 713 00:43:18,540 --> 00:43:21,900 sometimes it even worse cases, like mom said, you can develop hives all 714 00:43:21,900 --> 00:43:25,740 throughout your body or sometimes the, you know, your throat can close up so 715 00:43:25,740 --> 00:43:27,740 much that you might even suffocate. 716 00:43:27,900 --> 00:43:30,140 Um, and that's, and we call that anaphylactic shock. 717 00:43:30,460 --> 00:43:33,100 Um, when the, when the allergy is really bad. 718 00:43:33,820 --> 00:43:38,540 So, uh, in order to avoid this, like my mom said, you want to avoid the 719 00:43:38,540 --> 00:43:41,260 allergen altogether if you know it. 720 00:43:41,260 --> 00:43:44,780 Um, and that can be done by, like you said, it has to do with pets, don't 721 00:43:44,940 --> 00:43:47,500 have pets or try to limit your exposure to them. 722 00:43:48,300 --> 00:43:54,780 And if you have to be exposed to them, um, it might be good to have a filter 723 00:43:54,780 --> 00:43:58,860 in your house that can filter out some of this dander and also maybe potentially 724 00:43:58,860 --> 00:44:02,700 find a way to, um, expose yourself slowly to this dander. 725 00:44:02,700 --> 00:44:05,180 So maybe you can build up an immune tolerance. 726 00:44:05,500 --> 00:44:07,100 Uh, there's no guarantees there. 727 00:44:07,100 --> 00:44:10,700 Um, it definitely helps if you're younger, um, because your immune system 728 00:44:10,700 --> 00:44:11,740 is more adaptable. 729 00:44:12,380 --> 00:44:16,220 Uh, but if you're older, it might be good to try to build up some tolerance there. 730 00:44:16,940 --> 00:44:20,220 So, but when you have the allergic reaction, when you're actually suffering 731 00:44:20,220 --> 00:44:25,820 through something, it's good to, um, take things like decongestants, antihistamines, 732 00:44:25,980 --> 00:44:29,900 and sometimes even things like Tylenol, uh, because some of the swelling can be 733 00:44:29,900 --> 00:44:35,020 caused by prostaglandins, which if you want to take, uh, Tylenol, it can reduce, 734 00:44:35,020 --> 00:44:39,580 um, the prevalence of those prostaglandins and reduce some of the pain, um, that is 735 00:44:39,580 --> 00:44:40,940 happening inside of your body. 736 00:44:41,340 --> 00:44:46,940 Um, Professor Seltzer, did I gather everything that you said, or do you 737 00:44:46,940 --> 00:44:47,740 have anything to add? 738 00:44:48,220 --> 00:44:51,500 Yeah, I'm not sure that let me just double check. 739 00:44:51,660 --> 00:44:56,380 I mean, you could take something like ibuprofen to reduce prostaglandins, but I 740 00:44:56,380 --> 00:44:59,180 think Tylenol has a different mechanism. 741 00:44:59,180 --> 00:44:59,660 You're right. 742 00:44:59,660 --> 00:45:00,940 It's not really for pain. 743 00:45:00,940 --> 00:45:03,180 Tylenol is just blocks the, the nerve. 744 00:45:03,180 --> 00:45:06,860 Right. And ibuprofen is, is the prostaglandin. 745 00:45:06,860 --> 00:45:07,340 Thank you. 746 00:45:07,340 --> 00:45:08,300 I appreciate the correction. 747 00:45:08,300 --> 00:45:08,540 Yes. 748 00:45:08,540 --> 00:45:11,100 See, it's good to be wrong because then you find out what's right. 749 00:45:11,340 --> 00:45:17,580 So, um, and also to just add another, and one extra little caveat is that, you 750 00:45:17,580 --> 00:45:21,820 know, there are, there are now two kinds of classes of antihistamines. 751 00:45:21,820 --> 00:45:25,980 Those first generation antihistamines cause a lot more sedation, but we have 752 00:45:25,980 --> 00:45:29,580 the newer non-sedating antihistamines things that you're really familiar with, 753 00:45:29,580 --> 00:45:30,540 things like Allegra. 754 00:45:30,540 --> 00:45:33,340 Or Claritin. 755 00:45:33,340 --> 00:45:37,900 Um, and, uh, if you need to function during the day, I would suggest a 756 00:45:37,900 --> 00:45:41,980 non-sedating antihistamine and save those sedating antihistamines if you 757 00:45:41,980 --> 00:45:43,500 need to use them in the evening time. 758 00:45:43,660 --> 00:45:44,220 That's good to know. 759 00:45:44,220 --> 00:45:48,060 And do you suggest any decongestions that, that you prefer that you like? 760 00:45:48,300 --> 00:45:52,700 Um, I think that all of the, I mean, I, you know, probably, you know, 761 00:45:52,700 --> 00:45:56,460 Afrin or the Afrin generics are, are just fine. 762 00:45:56,460 --> 00:45:57,740 You know, any of those in that. 763 00:45:57,740 --> 00:46:00,780 Area are just going to be fine. 764 00:46:00,780 --> 00:46:03,740 And you would look on the back of the box and look for Afrin if you're looking for 765 00:46:03,740 --> 00:46:04,300 a decongestion. 766 00:46:04,300 --> 00:46:11,100 Well, I think that the, uh, the generic name for Afrin is oxymetazoline. 767 00:46:11,100 --> 00:46:12,460 I think, let me just double check that. 768 00:46:12,940 --> 00:46:13,660 Hold on. 769 00:46:14,220 --> 00:46:14,780 Yes. 770 00:46:14,780 --> 00:46:18,140 Ox, oxymetazoline is, uh, I'm sorry. 771 00:46:18,700 --> 00:46:22,220 Oxymetazoline is the generic name for Afrin. 772 00:46:22,220 --> 00:46:22,860 Okay. 773 00:46:22,860 --> 00:46:25,260 So if I see oxymetazoline, right. 774 00:46:25,260 --> 00:46:27,260 Then that's a, that's a generic name. 775 00:46:27,260 --> 00:46:28,380 That's a decongestion. 776 00:46:28,380 --> 00:46:29,660 That is a decongestion. 777 00:46:29,660 --> 00:46:30,060 Yes. 778 00:46:30,060 --> 00:46:30,460 And stuff. 779 00:46:30,460 --> 00:46:35,260 So it's, you, it's over the counter, you know, in, in the grocery stores and 780 00:46:35,260 --> 00:46:36,460 pharmacies and stuff. 781 00:46:36,460 --> 00:46:37,180 So, okay. 782 00:46:37,180 --> 00:46:38,540 Is that different than mucinex? 783 00:46:39,180 --> 00:46:39,500 Yes. 784 00:46:39,500 --> 00:46:41,180 Mucinex is totally different. 785 00:46:41,180 --> 00:46:44,620 Mucinex is for cough. 786 00:46:45,740 --> 00:46:49,500 It has a, an expectorant in it. 787 00:46:49,500 --> 00:46:53,340 And if it, if the dextromethorphan is in it, then it's got a cough suppressant. 788 00:46:53,340 --> 00:46:54,540 It's totally for cough. 789 00:46:54,540 --> 00:46:55,260 Gotcha. 790 00:46:55,260 --> 00:46:55,820 Okay. 791 00:46:55,820 --> 00:46:57,420 That's great. 792 00:46:57,420 --> 00:47:02,620 Um, well, y'all, this has been a lot and there's a lot to learn about allergies 793 00:47:02,620 --> 00:47:06,060 and, um, how your immune system, um, interacts. 794 00:47:06,060 --> 00:47:08,220 It's not very straightforward. 795 00:47:08,220 --> 00:47:12,940 Um, so we hope that you don't mind us not giving very straightforward answers. 796 00:47:12,940 --> 00:47:14,940 The mechanism can be so different. 797 00:47:14,940 --> 00:47:18,460 Like we said, there's four different mechanisms for, um, you know, allergic 798 00:47:18,460 --> 00:47:23,980 responses, uh, but to treat the conditions, um, is, is fairly consistent. 799 00:47:23,980 --> 00:47:26,860 Um, so we hope that some of this information is super helpful to y'all. 800 00:47:27,340 --> 00:47:29,980 Um, and we hope that you get some relief, especially when you're going 801 00:47:29,980 --> 00:47:33,100 through an allergy season or an allergy episode. 802 00:47:33,740 --> 00:47:37,740 Um, so until next time, um, my name is Josh Klaus. 803 00:47:38,860 --> 00:47:40,380 And I'm Jennifer Seltzer. 804 00:47:40,380 --> 00:47:54,380 And thanks for listening to another episode of Your Mom on Drugs.