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What's up guys? It's been a minute since I got to put an episode up here on all of these

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podcasting platforms but if you haven't heard yet, we're over on Facebook live. Head over

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to Facebook live. We're trying to do as much on there as possible and monetize on there.

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And then we're going to swing back around all these podcasting platforms. Finish season

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three, get some more guests on the show. Line up season four. And yeah, we're going to have

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some good guests. So today we got the interview with Anna Schwabbe and she's a doctor. So

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hope you guys enjoy this. Talk soon. Tell me a little about yourself. Tell me a little

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about what you do. Hey, Ryan. Yeah, it was good to speak with you the other day. So I'm

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Dr. Anna Schwabbe. I got nicknamed Dr. Anibis about three years ago, which I think is pretty

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funny and I just kind of ran with it. But I have a PhD in cannabis genetics. It's a pretty

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interesting and lengthy story, but basically I got interested. Well, I've always been interested

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in cannabis ever since, you know, probably high school. But I really got into cannabis

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and kind of thinking about cannabis research when I was working at the Denver Botanic Gardens

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back in, let's see, this was 2012 to 2015. Thinking about various questions that were

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coming up after the legalization for adult use in Colorado. And the number one thing

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that stuck out to me was people saying that if they go to different dispensaries and buy

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the same kind of flower, the same strain, they didn't have the same effects. And I thought

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that was really strange because, you know, if it's got a name, like if it's a Granny

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Smith apple, you should be the same, we're relatively the same with a little bit of variation,

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you know, because it's a plant, no matter where you get it. And so that's kind of where

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my interest started. And I brought it up to my to my mentor that I had for my master's

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degree and the school, the University of Northern Colorado, we were able to kind of

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figure out a way for me to get some research done with high THC type cannabis, which is

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basically not a thing at universities here in the United States. Most of the cannabis

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research is is limited to hemp research, because TAC type cannabis is still federally

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illegal. And so a lot of universities don't, they don't want to touch it. So I kind of

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was in this really unique position where I was able to get a PhD in cannabis genetics

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with high TTC type cannabis from dispensaries answering questions that really were consumer

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driven, consumer focused. So I was going into dispensaries and buying weed just like anybody

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would and then conducting experiments, not partnering with a cultivator or partnering

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with a lab, like it was all just kind of like super secret off the shelf testing kind of

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stuff to answer some of these really crazy questions. And it was awesome. And it took

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me four years, I could have done it quicker, but they wanted me to slow down, pump the

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brakes. But I think I got five publications out of that, which a lot of people would be

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familiar with. You know, the big one is that, you know, strains aren't always what they

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say they are. And then the other one is the TAC inflation that everybody's talking about

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these days. That was another one that was very popular. And then the other one was that

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the cannabis used for research, the research grade marijuana from the University of Mississippi

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is more closely related to hemp than it is to anything that any consumers, patients or

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recreational have access to, which is really odd. But yeah, so that's that's who I am.

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That's what I've done. And what I'm doing now is looking for a job.

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We had spoke about that. And that's very, that's very unfortunate. And what's your

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we're going to we're going to hop back to that in a second here. But the the blue dream,

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I believe you're talking about and how it's you were ever you compared it to a Granny

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Smith apple and how you would assume since they are all blue dream that you know, there

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might be, you know, they should all have the same taste. You know, you know, a Granny

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Smith apple to have like that sweet tart taste to it, right? You know, a little bit south.

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Yeah, there's a there's like a level of expectation that a Granny Smith should be it should be

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green. It should be round. It should be tart. Depending on where they're grown, though, I

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mean, they are going to be differences, right? So a Tasmanian, if you know where Tasmania

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is, it's a state in Australia, the little bottom island of Australia. So they're really

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well known for their apples, actually, but a Granny Smith grown in Tasmania might be

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different from a Granny Smith grown in California. But they have they have various features that

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that make them a Granny Smith, like you would never you would never confuse a Granny Smith

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with a golden delicious apple, right? They're they're they're different. And if the thing

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with like, you know, lots of things like dogs, like I have Docsons, all three look different,

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but there is a set of traits that hold them together as and make them identifiable as

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Docsons, right? You would never look at a Docson to be like, that's a great thing.

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Right.

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So you're like, hot dog, because hot dog dog. Yeah. And I had like one short hair, red

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Docson, one short haired black and dappled Docson. And then I have a long hair double

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dappled Docson. And they all look really different, but they all still are very identifiable

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as Docsons. And so when I'm talking about Blue Dream, for example, like, there should

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be something similar about Blue Dream, no matter where you get it. And the consumers

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really don't have any information other than the name on the package and potentially the

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TTC content to tell you that it's Blue Dream. And it's not only consumers, right? So if

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you're a cultivator and you order seeds of Blue Dream, which isn't a thing because Blue

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Dream was not ever stabilized, it should be a clone only. But let's say you order some

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clones, you have to go off there, the person who's supplying you with that, those clones

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that they are giving you Blue Dream and that they had received Blue Dream to make cuts

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from. So like there's this whole thing all the way down the chain of command where there's

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no, there's literally no checks. And what do I want to say? There's no way to check that

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you have the thing that you think you're getting, you just have to kind of trust it, trust

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the process. And mask up in a certain sense, because they're

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they're always talking about regulation and there's all these rules and like just the

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future is definitely coming together. It's just having these extra things like, for example,

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you were talking about the stabilization of the of Blue Dream. And I'm thinking, including

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myself, I would not, I really wouldn't have known that it's, you know, Blue Dream, you

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mentioned that being not being stabilized. What exactly does that mean?

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So to stabilize your genetic line, what you need to do is basically breed out all the

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variation. So it takes multiple generations of putting to like, and it might be easier

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for people to think of two dogs. Okay, so you get you go to the pound, you pick up two

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dogs, and you're hoping to make a new breed. Those two dogs are muts and they have a combination

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of multiple different types of dogs in them. You breed them together. That first letter

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is going to have a whole lot of variation in it. So then you're going to take a couple

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of the puppies and breed them together and try to start breeding it, reading, choosing

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the traits that you want, and getting rid of the traits that you don't. So you're going

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to pick the perfect, the, you know, the two perfect, or you can even back cross to one

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of the parents. And you're going to start breeding and eliminating individuals that

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have traits that are undesirable and keeping it and in breeding for the traits that you

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are looking for. And we all, you know, have been conditioned to know that inbreeding is

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a bad thing, right? When you inbreed, especially people and you get, you get some things that

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come along with that, you know, certain diseases and things like that. But that's, that's how

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we get stable lines is we inbreed until, you know, when you breed two toxins together,

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you get all baby toxins, you won't get an accidental dalmatian out of a litter of toxins

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that have been bred from purebred toxins. So really what, what that stabilization is

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doing is, is creating non variable traits, right? That makes sense. No, you're definitely

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not going to get a dalmatian by breeding two. That's how, that's how, that's how you make

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a cultivar, right? So cultivars, there's this whole ongoing debate about, we shouldn't

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say the word strain, we should use cultivar, right? But a cultivar is something that has

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been bred and selected for and is stable, for the most part. I mean, there's, there's

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a couple of exceptions, like if it's, you know, propagated through clone only, you know,

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it has to be novel, distinct in uniform, and stable, like those are just the things that

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a cultivar has to be. So I kind of think about it, like a lot of things on the market, including

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blue dream, they're not stable. Like if you put two different blue dream plants together,

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you're still going to have a lot of variation in that offspring. And that's why they say

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it's clone only is because you're not going to get those, that set of traits that you

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were looking for, if you breed blue dream from seed, right? So that's what clone only

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means. But there's lots, there's quite, there's a few, there's a few cannabis varieties out

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there that, you know, would be considered cultivars that they've been around for years,

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that you know what you're going to get when you grow them from seed. But the problem with

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cannabis is that again, it's federally illegal. So there's no way to register, register new

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cultivars really at this time. And so it just makes a lot more sense if you find something

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that you like, you know, you, you, you put two things together, you get offspring, you

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like this, it's just easier to grow up a plant and then, and then clone it instead of going

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through all of that, that whole process of breeding out all of the undesirable traits,

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which takes a lot of time, a lot of resources, a lot of, you know, like it's, it's a long

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process. And it's just easier to cut off bits of the plant and start growing new plants.

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Right? Yeah. So I think that's, and it's pretty unique to cannabis because it has been illegal

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for so long that, you know, creating cultivars and breeding out undesirable traits just isn't

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really worth it for most people. It's just like, oh, let's find something we like, and

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then we'll just clone it. So it's kind of, and then people will, you know, breed it with

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something else or, or they'll self like they'll create feminized seeds, which is fine. You

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can, you can do that and create a pretty, pretty good stable seeds and they'll be female,

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which is great. But it's like this mishmash patchwork of everything out there. I don't

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know if that makes sense. No, it is. It's a, it's definitely a thorough, very thorough

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long process. I'm not a breeder, but I've done some research. You've done a lot of research.

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A lot of it. I don't think how long have you been doing this for? Because this is, this

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is very, people need to know this perspective. How long have you been doing this?

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Well, my interest in cannabis started in about 1993, where I tried to grow some cannabis,

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but my parents caught me and I got in trouble. But I started seriously researching cannabis

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in 2015. So almost, it's so nine years. And that's, that's like day in, day out. That's

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my job is to sit, you know, through grad school was doing experiments on cannabis, reading

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everything, reading every book, every paper, everything that I possibly get my hands on

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to learn everything that I possibly could. And, and that's just in one like facet of

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cannabis, you know, I don't know much about like extracts, extractions and things like

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that. Like there's a whole not that there's so many arms in the cannabis industry. And

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I just am in one little bubble of it. But yeah, nine years of me, you know, working

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40 plus hours on just cannabis.

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I'm telling you, there are, I would say four out of five people, three out of five people

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ish right now would be like, wow, I really want her job. I would really have liked to

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do that.

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You know,

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I don't have

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right. We're about to jump into that next year. Because you were doing, you were doing

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some, some work where we were not we were you were planting hemp in sort in like forested

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areas. So give me a give me a little background on that.

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Yeah. So, well straight out of grad school, I actually worked for a company called mile

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high labs in Colorado, and I was doing some research stuff with them. My title was research

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coordinator and we were trying to get some research set up to do like pre clinical stuff

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on various minor cannabinoids, which there's not a lot of research out there. People always

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ask me, what does CBG do? What does CBN do? And I'm like, well, you know, we don't know

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very much. But that job, that job got that was only a short lived position because the

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company kind of imploded. But then I was picked up by a company in New Jersey, a startup

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company called shore organics slash 420 organics. And they moved me out to New Jersey and they

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have a hemp farm where they use aquaponics methods to grow CBD type hemp that will eventually

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go for extraction. But yeah, it's out in the forest in New Jersey. And we were, we had

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fish that poop, and then that poop would get processed through various biological filters,

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shrimp and microbes and things like that. And then when we'd use that nitrate rich water

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to feed the plants. And it's all organic, we didn't add anything else like no, no other

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amendments to the soil was a living soil situation as well. So yeah, so that's what we were doing.

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Pretty cool stuff. I was with that company for three and a half years up until just about

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three weeks ago, they had to let me go because they had run out of money, which is, you know,

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one of the, one of the things that comes with working for a startup in cannabis, probably

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in any industry really startups are sometimes they don't work out. So hopefully this company

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will keep going. I really like what they're doing. And they're, they're planning to expand

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into the THC market as well. They've got the licenses. It's just been a really slow, long

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process here in New Jersey. The regulators are just dicking around and you got to deal

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with townships and whatnot. But I hope that they keep going and I hope that they do well.

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They haven't, they haven't totally like thrown in the towel yet. So I'm some funding, find

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someone, find some investors, you know, as this sounds like something you would like

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to be part of. I'm going to include Anna's information here in the website description,

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I mean the website, the episode description. So there'll be a link to her website where

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you'll be able to learn a little bit more about her and contact her if you have any

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questions and if she can point you in the right direction. You know, this is something

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that both Anna and I love to do is talk cannabis, be around cannabis. And a lot of the things

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going forward matter about what people like Anna are doing, trying to do, are going to

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do. So we are coming to a day where there's a lot of things changing, a lot of laws that

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are changing. There's been a farm bill, which has garnered a lot of attention. So I kind

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of wanted to get your opinion on that. Proposals looking like that it's going to go disapproving

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or not disapproving, but kind of making like HHC, which is a naturally occurring cannabinoid

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in the plant in some variations. HHC does not occur in the plant at all. It's the plant,

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no, no, no. Nope. Nope. Nope. What I had read is it said that in some African strains

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that HHC no pops up as a semi occurring or something of that nature. I would love to

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see that. I have never heard that and I've never seen that. And I talked to a lot of

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people who do a lot of testing. There are some African strains that have TACV, but HHC

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is not a naturally occurring cannabinoid. And there's, it has to be done in a lab. Just

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the nature of the molecule doesn't occur in nature.

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Yeah. I had read in a couple of places that HHC was found in veer, like we're talking

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semi microscopic amounts in African strains. It was something I had seen, but that's probably

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subjective to the type of testing that's been going on or something. I don't know. I know

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that it's a hydrogenated version of TACV, how that could happen in a plant. It was fascinating

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to me, but like CBN, CBD, CBG, CBDC or CBC or whatnot, kind of leaves a lot of questions

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in the air of what's going to happen.

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So yeah, so let's talk. So the plant technically doesn't even make Delta 9 THC or CBD or CBG

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or CBC. The plant makes the acidic versions of those, right? So we have CBGA, which is

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cannabinorolic acid.

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I'll say that. So technically, the plant makes the acidic compounds. So we have CBGA is the

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first compound that's made in the cascade of molecules and that's cannabinorolic acid.

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And then the synthases, the enzymes that convert that to THCA, CBDA and CBCA are in the plant.

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So that's what the plant makes is those acidic molecules. The plant doesn't actually make

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Delta 9 THC or CBD or CBC. Those acidic molecules have to be decarboxylated in order for those

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to occur. The plant would not be in any sort of conditions where any of those molecules

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would be decarboxylated in any respectable levels, right? So any plant that you grow,

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if it's got, if it even the THC dominant plants, there's going to be very low levels

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of Delta 9 THC because the plant doesn't make that. It takes an outside source heat or acid

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or UV or something for that decarboxylation of that acidic molecule to happen. So that

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being said, with the Farm Bill, what they're trying to do is address these intoxicating

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hemp derived cannabinoids. So some of them are naturally occurring. They naturally can

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decarboxylate or all you have to add is heat and they will naturally carboxylate or they

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will degrade. Delta 8 and CBN are a natural degradance of Delta 9. So those might show

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up in very small quantities. If the plant has been not stored well or in a jar on your

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windowsill for a couple months, then you're going to start seeing those levels go up, but

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the plant doesn't make those, but they are naturally occurring. The ones that are not,

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things like THC, THCO, Delta 10, I can't even think of, there's like a whole bunch of them,

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right? THCP is naturally occurring, but again, not in any kind of respectable amounts, very

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micro quantities such that you wouldn't be able to grow enough hemp or to get any kind

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of decent quantity of THCP to sell or to put into whatever. So that is also made in a lab

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and what they do is they take CBD, like so they take the CBD, make it into CBD, extract,

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do the extracts, make an isolate and they take the isolate and then they make it into other

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things. So they're taking, the problem, there's a couple of different problems. CBD is an

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approved drug by the FDA for Epidiolex. So what they're doing really is taking an approved

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drug ingredient and making other things that are not approved, they're not regulated, they're

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not anything. And when they do this, when a lot of people do this, not only are the compounds

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that they're trying to make are made, but there's a lot of byproducts that are also

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made. We don't even have names for them. We don't know what they are. They show up on

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the mass spec chromatogram and you can see all these peaks, but we don't know what they

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are. They're not even named yet. They're not described. We have no idea what they are.

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We don't know if they're safe or anything like that. And then also when people do these

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chemical reactions, a lot of Delta 9 THC can be made. So these products can also have more

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Delta 9 THC than they're supposed to in order to be hemp. And there are some companies that

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are doing it right, but there's a whole lot of people that are just making it to make

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money. And the thing about the Farm Bill, so the Farm Bill in 2018 clarified some language.

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There was the interim rules and then the final rules which came out and were in effect

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in 2021. They clarified that hemp is anything below 0.3% total THC, not just Delta 9, but

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total THC. That and the Farm Bill only regulates up until that pre-harvest compliance test.

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Then depending on which state you're in, you've got 15 to 30 day window to which you have to

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harvest. So 30 days is the maximum amount of time that you have from that test that is

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compliant to harvest that plant. And there's no THC dominant plant in the world that is

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going to go from less than 0.3% total THC to 20% plus THC in 30 days. It just won't happen.

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Like you won't be able to pass that compliance test anyway. So the issue is that now there's

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a bunch of stuff that's called THC-A hemp, right? Because it's got very little Delta

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9 THC and a lot of THC-A. But that's any cannabis plant that has is THC dominant. They're all

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going to be like that because that's what the plant is until you heat it up and do things

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with it. And those products, THC-A hemp is not regulated. It's not tested for pesticides

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because the only test that you have to do when you're growing hemp is that compliance test.

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They don't care because hemp was never meant to be a consumable product. So you don't have

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to do microbials. You don't have to do terpenes. You don't have to do heavy metals. You don't

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have to do mycotoxins. You don't have to do any of those tests that you have to do if

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you're in the regulated marijuana market, right? So where is all this THC-A hemp coming

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from? Because it's not coming from the hemp cultivators. So it's either coming from illicit

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grows or there's another theory out there that it's coming from failed marijuana cultivations.

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Like they failed pesticides or mycotoxins or molds and instead of destroying it, they're

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like, well, we'll just slap a label on it and call it THC-A hemp because it's still below

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0.3% delta 9, which is the CSA, the controlled substances act still says 0.3% delta 9 THC.

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So technically it falls under hemp for the controlled substances act, which is what the

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DEA enforces. If you read the CSA further down from where it gives the definition of

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hemp, it does say hemp according to the USDA definition. And then you go to the USDA final

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rules which say total THC. So I don't know. There's a lot of, there's gray area. And in

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terms of making all of these compounds from CBD, the definition does say any part of the

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plant growing or not with a less than delta 9 concentration of 0.3 plus all of its isomer

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salts, blah, blah, blah, blah, blah, derivatives. And technically those are all derivatives.

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So lawyers are fighting about it. And there's people making money off of this and it could

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all be solved if we just legalized cannabis. Why would we have all these weirdo things

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for people to enjoy if it was, I think people would choose to plant over these weirdo Frankenstein

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chemically lab made things. But a lot of states still don't have access to that, right? But

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nonetheless, we have this and you know back in 2018, 2019, the market was flooded. Everybody

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thought, oh, we can grow hemp. Growing hemp is going to be amazing. Let's grow lots of

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hemp. Lots of farmers grew hemp. The market was flooded with CBD. And the price tanked

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and then a lot of people were left holding a shit ton of CBD isolate and they couldn't

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sell it. So I think it's really innovative that people were able to, you know, figure

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out a way to do what they needed to do with the CBD they had converted into other things

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that people could use. People really like it. I don't fault anybody for doing that. But

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you know, here we are. And I don't think that the farm bill, so the farm bill has to be,

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it's supposed to be revisited every four to five years. And so 2018 was the last revision.

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The final rules went into effect in 2021. But 2018, we're well overdue for a revisit

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of the farm bill. And the farm bill is huge. It doesn't just cover hemp. It covers, you

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know, everything. It's a very large piece of legislation. That being said, you know,

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is it Mary Miller proposal that you ban everything, blah, blah, blah, people are freaking out.

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We have to remember that the farm bill really only applies to cultivators. It's a USDA

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thing. If you're manufacturing products post harvest, the farm bill doesn't really apply

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to you. So putting that stuff in the farm bill doesn't, it's not going to affect cultivators

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at all. They're still beholden to the less than 0.3% total THC they have since 2021.

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So everybody who's freaking out about it is on the other side of the cultivation, on the

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other side of harvest. So I don't know what's going to happen with that. But people seem

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to forget that. Yeah, there's, there's a lot of you had, you had alluded to look like

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the THCA for example. I myself buying product when I, when I first started getting, because

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we do hemp extracts, we do like CBD, CBD, and I say hemp extracts, I mean, by definition

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of the current word hemp, which is 0.3, because it's basically just a made up word for cannabis

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in relation to our laws. But so we were doing a lot of those products when it first started

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to get out. And initially we had found that some of the THCA did have some mold on it.

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But we weren't, we had just thought, we had just thought of that as like a one time something

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like really messed up happened, like specifically isolated incident to us. It wasn't, it was

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something that had happened to multiple companies. It was something that, so you are, you are

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right. That is not, that's not something to be taken lightly or, you know, to mess around

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with under that would be really messed up. And that's what was going on. That's very

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interesting. Yeah. And, you know, it's awesome that, you know, you can get THCA flower in

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states where cannabis is not legal. You know, I have a friend who lives in Texas, for example,

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and she's like, I can't get, I can't, I can't get it anyway. She's like, I can't wear my

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own, and I don't want to bring it across state lines. Like, I don't know where to, I need

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cannabis and I don't know where to get it. And I'm like, babe, THCA hemp is, is what

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you're looking for. That's just weed. It's just weed. It's just weed. Go buy that. And

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she's like, you know, she didn't, she, she doesn't know a lot about cannabis. She just

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knows that she needs it all day, every day to function. She's got pretty severe ADHD,

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among other things. But yeah, she was like, dude, this is totally just weed. I'm like,

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I know, it's totally just weed. Totally. Just totally is just. It totally is just weed.

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You know, but, but buyer beware, right? So if you're using it for medicine, or if you

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are immunocompromised or whatever the case, you do need to be careful of these products

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because they are unregulated. We don't know where they came from. They haven't been through

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the rigorous testing requirements that the adult use and medical use industries are,

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are beholden to. Maybe there are some companies that are doing full panel tests, but they

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don't have to. And also, there are all kinds of COAs that are just fudged or, you know,

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made up or not for that product, because these are, again, the track and trace system isn't

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there anymore. Not that that track and track. If the track and trace system actually worked,

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we wouldn't, you know, have all of this going on. But, and, you know, I mean, it's, we don't

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need more regulations. We just need the regulations to be enforced. You know, it seems like the

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regulators, they got one job and that's to regulate and nothing, it seems, is being

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regulated. We've got THC inflation. We've got off the shelf testing flower that's failing

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mold and yeast and pesticides and heavy like, what are the regulators doing? Why did they

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come up? Why did they spend all this time coming up with all these rules if they're

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not actually going to enforce them and make sure that people are putting out safe products?

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I don't know. I don't get it. Maybe they need to hire me. Yes. Yes. Exactly what they need

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to do. Consistency would be nice. Consistency is the key of the, you know, we just all need

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to really like just know what we're working with at this point and move forward from that.

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And it would be nice to just kind of bypass all that and let's just legalize it. And it

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would make things a hell of a lot easier, especially for both of us. It would make things

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a lot easier for both of us. But I don't want us to get cut off from our, our meeting today

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or chat today. I like your earrings, by the way. I didn't notice what they were. Oh,

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oh yeah, these are fantastic. Yeah, these are my little black dress of my cannabis earrings.

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They're from a company called High on Plants, which is Alice Moon. She's pretty well known

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in the cannabis community, but she just started this company, I don't know, like a year ago.

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I have every single color they put out. And they even, they did a tie dye one for a Pride

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Month. And then I suggested they do a leopard print one. And they did. And they are fricking

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awesome. So if you want their leather, their leather, which is really cool, because a lot

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of the metal ones are super pokey and not super comfortable, especially if you end up

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eating them like taking a nap and then you end up with like your holes in your face, but

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they're leather. So they're really soft. And I love them. I get a lot of compliments. Highly

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recommend looking them up. Maybe not for you, but if you know any females in your life that

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like cannabis jewelry, High on Plants is the name of the company.

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Thank you. High on Plants. People will definitely hear that on the podcast. So check that website.

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I'm going to put your website here in the description. And we're going to have to schedule

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another talk soon. I enjoy talking with you. I definitely learn things when I talk with

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you helps me out. And yeah, we could do a part two, we could even do a whole series.

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We should. We should probably do really well, actually.

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Well, I'd be happy to. I love, I love, I love talking about weed is my favorite thing to

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do. And I have a lot to say in case you didn't notice. So

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all right, I appreciate everybody for listening today. This is a prerecorded episode. Check

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in and the next 48 hours, I'll have another podcast episode available on Facebook live.

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So go to only the best herbs podcast community and store. Join our community. You'll see

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the lives posted there. You can follow me. You'll definitely see the lives posted there.

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And yeah, I appreciate everybody. Talk soon.

